Correction to: Vaschetto Crit Care (2021) 25:189 https://doi.org/10.1186/s13054-021-03595-5
Following publication of the original article [1], the authors identified an error in Table 1. The correct Table is given hereafter.
Table 1
Characteristics of the randomized control trials included in qualitative synthesis
Study | Setting | Primary endpoint | Secondary endpoints | Number of patients included in the original paper | Baseline characteristics of patients at entry into the study | Number of excluded patients and reasons | Number of patients potentially to be analyzed | Number of patients analyzed |
|---|---|---|---|---|---|---|---|---|
Ferrer et al. 2003 | 2 Spanish hospitals | The decrease of the duration of invasive ventilation defined as positive pressure ventilation delivered through orotracheal intubation or tracheotomy, in the NIV group. | 1. Total period of ventilatory support 2. ICU length of stay 3. Hospital length of stay 4. Reintubation 5. Main causes of reintubation -Severe persistent hypoxemia -Severe dyspnoea -Inability to manage secretions -Hemodynamic instability 6. Tracheotomy 7. ICU survival 8. Causes of death within 90d after entry in the study -Septic shock/MOF -Refractory hypoxemia -Cardiac arrest -Pneumothorax -Stroke -Pulmonary embolism | 43 patients 21 NIV 22 Control | 1. Age 2. Sex 3. Current or former smoker 4. Current of former alcohol abuse 5. APACHE II 6. Duration of ICU stay 7. Duration of mechanical ventilation 8. Number of comorbidities per patient 9. White blood cells 10. Haematocrit 11. Patients with chronic pulmonary disorders 12. Causes of mechanical ventilation -Exacerbation of chronic pulmonary disorders -Congestive heart failure -Community-acquired pneumonia -Hospital-acquired pneumonia -Postoperative respiratory failure -Acute lung injury -Thoracic trauma -Haemoptysis -Cardiac arrest | 17 acute-on-chronic exacerbation COPD 9 acute cardiogenic pulmonary oedema 3 severe asthma 8 chronic pulmonary disorder | 6 patients 4 Intervention 2 Control | 6 patients 4 Intervention 2 Control |
Trevisan et al. 2008 | Single-centre Brazil | To evaluate the use of bi-level NIV for patients who fail weaning from i-MV | 1. ICU length of stay 2. Hospital length of stay 3. otal length of stay in hospital 4. ICU death 5. Ward death 6. Mechanical ventilation time after randomization 7. Total mechanical ventilation time 8. Complications -Pneumonia -Sepsis -Congestive heart failure -Tracheotomy -Return to IMV -Skin necrosis | 65 patients 28 NIV 37 Control | 1. Age 2. Sex 3. APACHE-II 4. Duration of mechanical ventilation 5. Causes of mechanical ventilation -COPD aggravation and -Asthma -Heart diseases -Respiratory diseases -Post-surgery respiratory failure -Acute pulmonary lesion -Pneumonia -Tuberculosis -Thoracic trauma | 23 acute-on-chronic exacerbation COPD and asthma 11 acute cardiogenic pulmonary oedema 5 PaCO2 >50 mmHg and pH >7.35 2 age <18 years old | 24 patients 10 Intervention 14 Control | 24 patients 10 Intervention 14 Control |
Vaschetto et al. 2012 | Single-centre Italy | Duration of i-MV | 1. ICU length of stay 2. ICU mortality 3. Hospital mortality 4. Extubation failure 5. i-MV before T0 6. i-MV AFTER T0 7. 28-i-MV free days 8. 28-MV free days 9. Weaning 10. Side effects/complications of i-MV -Tracheotomy -Continuous i.v. sedation | 20 patients 10 NIV 10 Control | 1. Age 2. Sex 3. APACHE II 4. Causes of mechanical ventilation -Pancreatitis -Pneumonia -Thoracic trauma -Bowel obstruction | None | 20 patients 10 Intervention 10 Control | 20 patients 10 Intervention 10 Control |
Carron et al. 2014 | Single-centre Italy | Weaning success/failure rate | 1. Duration of i-MV 2. Duration of ventilator support for weaning 3. Duration of total ventilator support 4. Weaning failure 5. Reintubation -Refractory hypoxemia -Bronchial hypersecretion -Transient ischemic attack -Hypercapnia 6. Conventional weaning after reintubation with/without percutaneous dilatational tracheostomy 7. Main complication after entry in the study -VAP -Catheter-related pneumonia -Septic shock -Multiple-organ Failure -Disseminated intravascular coagulation -Cardiogenic
shock -Cardiac arrest 8. ICU length of stay 9. Hospital length of stay 10. ICU survival 11. Hospital survival | 64 patients 32 NIV 32 Control | 1. Age 2. Sex 3. Weight 4. APACHE II 5. ARF hypoxemic hypercapnic (n. of patients) -Exacerbation of chronic pulmonary disease -Asthma -Community-acquired bronchopneumonia -Hospital acquired-bronchopneumonia 6. ARF hypoxemic (n. of patients) -Postoperative respiratory failure -Community-acquired bronchopneumonia -Hospital acquired-bronchopneumonia -Acute cardiogenic pulmonary oedema -Congestive heart failure -Acute pulmonary embolism -Acute pancreatitis -Acute lung injury following ab ingestis -Thoracic trauma -Burn | 17 acute-on-chronic exacerbation COPD 1 Asthma 5 acute cardiogenic pulmonary oedema 4 BMI ≥30 10 PaCO2 >50 mmHg and Ph >7.35 | 27 patients 14 Intervention 13 Control | 27 patients 14 Intervention 13 Control |
Perkins et al. 2018 | 41 hospitals UK | Time from randomization to successful liberation from all forms of mechanical ventilation | 1. Mortality at 30, 90, 180 days 2. Duration of i-MV 3. Duration of total ventilation 4. Time to meeting ICU discharge criteria (defines as no further requirement for level 2/3 care) 5. Reintubation rates 6. Tracheostomy 7. Adverse events and serious adverse events | 364 patients 182 NIV 182 Control | 1. Age 2. Sex 3. Evidence of delirium 4. Body mass index 5. Duration of ventilation prior to randomization 6. Antibiotics for respiratory 7. Infections 8. APACHE II 9. Admission diagnosis -Pneumonia/respiratory infection -Post-surgery respiratory failure -Cardiac -Non-respiratory infection -Neuromuscular -COPD/asthma exacerbation -Traumatic injuries -GIT bleeding -Pancreatitis -Stroke | 15 neuromuscular patients 14 COPD/asthma exacerbation 33 acute cardiogenic pulmonary oedema 48 PaCO2 >50 mmHg and pH >7.35 | 254 patients 130 Intervention 124 Control | 254 patients 130 Intervention 124 Control |
Vaschetto et al. 2019 | 6 hospitals China 3 hospitals Italy | 1. Days of i-MV Overall Medical Surgical 2. ICU length of stay Overall Medical Surgical | 1. Treatment failure 2. Severe events 3. Tracheostomy 4. VAT 5. VAP 6. Use of sedatives 7. Hospital length of stay 8. ICU mortality 9. Hospital mortality | 130 patients 65 NIV 65 Control | 1. Main causes of i-MV -ARDS -Pneumonia -Septic shock -Polytrauma -Postoperative abdominal surgery -Postoperative vascular surgery -Postoperative thoracic surgery -GIT bleeding -Cerebral bleeding -Pancreatitis 2. Days of i-MV pre-protocol 3. Days of NIV pre-protocol | 2 PaCO2 >50 mmHg and pH >7.35 | 128 patients 65 Intervention 63 Control | 128 patients 65 Intervention 63 Control |
All the changes that were requested are implemented in this correction and the original article [1] has been corrected.
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