01.12.2021 | Research | Ausgabe 1/2021
Open Access
Accelerated versus standard initiation of renal replacement therapy for critically ill patients with acute kidney injury: a systematic review and meta-analysis of RCT studies
Heng-Chih Pan, Ying-Ying Chen, I-Jung Tsai, Chih-Chung Shiao, Tao-Min Huang, Chieh-Kai Chan, Hung-Wei Liao, Tai-Shuan Lai, Yvonne Chueh, Vin-Cent Wu, Yung-Ming Chen
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Venoarterial extracorporeal membrane oxygenation induces early immune alterations
Aurélien Frerou, Mathieu Lesouhaitier, Murielle Gregoire, Fabrice Uhel, Arnaud Gacouin, Florian Reizine, Caroline Moreau, Aurélie Loirat, Adel Maamar, Nicolas Nesseler, Amedeo Anselmi, Erwan Flecher, Jean-Philippe Verhoye, Yves Le Tulzo, Michel Cogné, Mikael Roussel, Karin Tarte, Jean-Marc Tadié
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Mechanical power during extracorporeal membrane oxygenation and hospital mortality in patients with acute respiratory distress syndrome
Li-Chung Chiu, Shih-Wei Lin, Li-Pang Chuang, Hsin-Hsien Li, Pi-Hua Liu, Feng-Chun Tsai, Chih-Hao Chang, Chen-Yiu Hung, Chung-Shu Lee, Shaw-Woei Leu, Han-Chung Hu, Chung-Chi Huang, Huang-Pin Wu, Kuo-Chin Kao
01.12.2021 | Research | Ausgabe 1/2021
Open Access
The immune modulatory effects of mitochondrial transplantation on cecal slurry model in rat
Jung Wook Hwang, Min Ji Lee, Tae Nyoung Chung, Han A. Reum Lee, Jung Ho Lee, Seo Yoon Choi, Ye Jin Park, Chul Hee Kim, Isom Jin, Seong Hoon Kim, Hyo-Bum Kwak, Jun-Won Heo, Kwangmin Na, Sangchun Choi, Yong-Soo Choi, Kyuseok Kim
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Alveolar compartmentalization of inflammatory and immune cell biomarkers in pneumonia-related ARDS
Inès Bendib, Asma Beldi-Ferchiou, Frédéric Schlemmer, Mathieu Surenaud, Bernard Maitre, Anne Plonquet, Guillaume Carteaux, Keyvan Razazi, Veronique Godot, Sophie Hüe, Armand Mekontso Dessap, Nicolas de Prost
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Burden of pneumococcal pneumonia requiring ICU admission in France: 1-year prognosis, resources use, and costs
Claire Dupuis, Ayman Sabra, Juliette Patrier, Gwendoline Chaize, Amine Saighi, Céline Féger, Alexandre Vainchtock, Jacques Gaillat, Jean-François Timsit
01.12.2021 | COVID-19 | Research | Ausgabe 1/2021
Open Access
Ventilator-associated pneumonia in critically ill patients with COVID-19
Mailis Maes, Ellen Higginson, Joana Pereira-Dias, Martin D. Curran, Surendra Parmar, Fahad Khokhar, Delphine Cuchet-Lourenço, Janine Lux, Sapna Sharma-Hajela, Benjamin Ravenhill, Islam Hamed, Laura Heales, Razeen Mahroof, Amelia Solderholm, Sally Forrest, Sushmita Sridhar, Nicholas M. Brown, Stephen Baker, Vilas Navapurkar, Gordon Dougan, Josefin Bartholdson Scott, Andrew Conway Morris
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Duration of diaphragmatic inactivity after endotracheal intubation of critically ill patients
Michael Chaim Sklar, Fabiana Madotto, Annemijn Jonkman, Michela Rauseo, Ibrahim Soliman, L. Felipe Damiani, Irene Telias, Sebastian Dubo, Lu Chen, Nuttapol Rittayamai, Guang-Qiang Chen, Ewan C. Goligher, Martin Dres, Remi Coudroy, Tai Pham, Ricard M. Artigas, Jan O. Friedrich, Christer Sinderby, Leo Heunks, Laurent Brochard
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Incidence, prognostic factors, and outcomes of venous thromboembolism in critically ill patients: data from two prospective cohort studies
Ruben J. Eck, Lisa Hulshof, Renske Wiersema, Chris H. L. Thio, Bart Hiemstra, Niels C. Gritters van den Oever, Reinold O. B. Gans, Iwan C. C. van der Horst, Karina Meijer, Frederik Keus
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Serum neurofilament measurement improves clinical risk scores for outcome prediction after cardiac arrest: results of a prospective study
Sabina Hunziker, Adrian Quinto, Maja Ramin-Wright, Christoph Becker, Katharina Beck, Alessia Vincent, Kai Tisljar, Giulio Disanto, Pascal Benkert, David Leppert, Hans Pargger, Stephan Marsch, Raoul Sutter, Nils Peters, Jens Kuhle
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Bedside POCUS during ward emergencies is associated with improved diagnosis and outcome: an observational, prospective, controlled study
Laurent Zieleskiewicz, Alexandre Lopez, Sami Hraiech, Karine Baumstarck, Bruno Pastene, Mathieu Di Bisceglie, Benjamin Coiffard, Gary Duclos, Alain Boussuges, Xavier Bobbia, Sharon Einav, Laurent Papazian, Marc Leone
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Association between perioperative fluid administration and postoperative outcomes: a 20-year systematic review and a meta-analysis of randomized goal-directed trials in major visceral/noncardiac surgery
Antonio Messina, Chiara Robba, Lorenzo Calabrò, Daniel Zambelli, Francesca Iannuzzi, Edoardo Molinari, Silvia Scarano, Denise Battaglini, Marta Baggiani, Giacomo De Mattei, Laura Saderi, Giovanni Sotgiu, Paolo Pelosi, Maurizio Cecconi
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Incidence and management of metabolic acidosis with sodium bicarbonate in the ICU: An international observational study
Tomoko Fujii, Andrew A. Udy, Alistair Nichol, Rinaldo Bellomo, Adam M. Deane, Khaled El-Khawas, Naorungroj Thummaporn, Ary Serpa Neto, Hannah Bergin, Robert Short-Burchell, Chin-Ming Chen, Kuang-Hua Cheng, Kuo-Chen Cheng, Clemente Chia, Feng-Fan Chiang, Nai-Kuan Chou, Timothy Fazio, Pin-Kuei Fu, Victor Ge, Yoshiro Hayashi, Jennifer Holmes, Ting-Yu Hu, Shih-Feng Huang, Naoya Iguchi, Sarah L. Jones, Toshiyuki Karumai, Shinshu Katayama, Shih-Chi Ku, Chao-Lun Lai, Bor-Jen Lee, Wen-Jinn Liaw, Chelsea T. W. Ong, Lisa Paxton, Chloe Peppin, Owen Roodenburg, Shinjiro Saito, John D. Santamaria, Yahya Shehabi, Aiko Tanaka, Ravindranath Tiruvoipati, Hsiao-En Tsai, An-Yi Wang, Chen-Yu Wang, Yu-Chang Yeh, Chong-Jen Yu, Kuo-Ching Yuan, for the SODA-BIC investigators
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Acute cholangitis in intensive care units: clinical, biological, microbiological spectrum and risk factors for mortality: a multicenter study
Jean-Rémi Lavillegrand, Emmanuelle Mercier-Des-Rochettes, Elodie Baron, Frédéric Pène, Damien Contou, Raphael Favory, Sébastien Préau, Arnaud Galbois, Chloé Molliere, Arnaud-Félix Miailhe, Jean Reignier, Mehran Monchi, Claire Pichereau, Sara Thietart, Thibault Vieille, Gael Piton, Gabriel Preda, Idriss Abdallah, Marine Camus, Eric Maury, Bertrand Guidet, Guillaume Dumas, Hafid Ait-Oufella
01.12.2021 | COVID-19 | Research | Ausgabe 1/2021
Open Access
Static compliance of the respiratory system in COVID-19 related ARDS: an international multicenter study
Benoit Vandenbunder, Stephan Ehrmann, Michael Piagnerelli, Bertrand Sauneuf, Nicolas Serck, Thibaud Soumagne, Julien Textoris, Christophe Vinsonneau, Nadia Aissaoui, Gauthier Blonz, Giuseppe Carbutti, Romain Courcelle, Alain D’hondt, Stephane Gaudry, Julien Higny, Geoffroy Horlait, Sami Hraiech, Laurent Lefebvre, Francois Lejeune, Andre Ly, Jean-Baptiste Lascarrou, David Grimaldi, for the COVADIS study group
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Renal dysfunction improves risk stratification and may call for a change in the management of intermediate- and high-risk acute pulmonary embolism: results from a multicenter cohort study with external validation
Romain Chopard, David Jimenez, Guillaume Serzian, Fiona Ecarnot, Nicolas Falvo, Elsa Kalbacher, Benjamin Bonnet, Gilles Capellier, François Schiele, Laurent Bertoletti, Manuel Monreal, Nicolas Meneveau
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Automated detection and quantification of reverse triggering effort under mechanical ventilation
Tài Pham, Jaume Montanya, Irene Telias, Thomas Piraino, Rudys Magrans, Rémi Coudroy, L. Felipe Damiani, Ricard Mellado Artigas, Matías Madorno, Lluis Blanch, Laurent Brochard, the BEARDS study investigators
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Monitoring circulating dipeptidyl peptidase 3 (DPP3) predicts improvement of organ failure and survival in sepsis: a prospective observational multinational study
Alice Blet, Benjamin Deniau, Karine Santos, Dirk P. T. van Lier, Feriel Azibani, Xavier Wittebole, Benjamin G. Chousterman, Etienne Gayat, Oliver Hartmann, Joachim Struck, Andreas Bergmann, Massimo Antonelli, Albertus Beishuizen, Jean-Michel Constantin, Charles Damoisel, Nicolas Deye, Salvatore Di Somma, Thierry Dugernier, Bruno François, Stephane Gaudry, Vincent Huberlant, Jean-Baptiste Lascarrou, Gernot Marx, Emmanuelle Mercier, Haikel Oueslati, Peter Pickkers, Romain Sonneville, Matthieu Legrand, Pierre-François Laterre, Alexandre Mebazaa, AdrenOSS-1 Study Investigators
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Impact of treating iron deficiency, diagnosed according to hepcidin quantification, on outcomes after a prolonged ICU stay compared to standard care: a multicenter, randomized, single-blinded trial
Sigismond Lasocki, Pierre Asfar, Samir Jaber, Martine Ferrandiere, Thomas Kerforne, Karim Asehnoune, Philippe Montravers, Philippe Seguin, Katell Peoc’h, Soizic Gergaud, Nicolas Nagot, Thibaud Lefebvre, Sylvain Lehmann, the Hepcidane study group
01.12.2021 | COVID-19 | Research | Ausgabe 1/2021
Open Access
Deploying unsupervised clustering analysis to derive clinical phenotypes and risk factors associated with mortality risk in 2022 critically ill patients with COVID-19 in Spain
Alejandro Rodríguez, Manuel Ruiz-Botella, Ignacio Martín-Loeches, María Jimenez Herrera, Jordi Solé-Violan, Josep Gómez, María Bodí, Sandra Trefler, Elisabeth Papiol, Emili Díaz, Borja Suberviola, Montserrat Vallverdu, Eric Mayor-Vázquez, Antonio Albaya Moreno, Alfonso Canabal Berlanga, Miguel Sánchez, María del Valle Ortíz, Juan Carlos Ballesteros, Lorena Martín Iglesias, Judith Marín-Corral, Esther López Ramos, Virginia Hidalgo Valverde, Loreto Vidaur Vidaur Tello, Susana Sancho Chinesta, Francisco Javier Gonzáles de Molina, Sandra Herrero García, Carmen Carolina Sena Pérez, Juan Carlos Pozo Laderas, Raquel Rodríguez García, Angel Estella, Ricard Ferrer, on behalf of COVID-19 SEMICYUC Working Group
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Prevalence of post-intensive care syndrome among Japanese intensive care unit patients: a prospective, multicenter, observational J-PICS study
Daisuke Kawakami, Shigeki Fujitani, Takeshi Morimoto, Hisashi Dote, Mumon Takita, Akihiro Takaba, Masaaki Hino, Michitaka Nakamura, Hiromasa Irie, Tomohiro Adachi, Mami Shibata, Jun Kataoka, Akira Korenaga, Tomoya Yamashita, Tomoya Okazaki, Masatoshi Okumura, Takefumi Tsunemitsu
01.12.2021 | COVID-19 | Research | Ausgabe 1/2021
Open Access
Markers of endothelial and epithelial pulmonary injury in mechanically ventilated COVID-19 ICU patients
Savino Spadaro, Alberto Fogagnolo, Gianluca Campo, Ottavio Zucchetti, Marco Verri, Irene Ottaviani, Tanushree Tunstall, Salvatore Grasso, Valentina Scaramuzzo, Francesco Murgolo, Elisabetta Marangoni, Francesco Vieceli Dalla Sega, Francesca Fortini, Rita Pavasini, Paola Rizzo, Roberto Ferrari, Alberto Papi, Carlo Alberto Volta, Marco Contoli
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Role of endothelial microRNA 155 on capillary leakage in systemic inflammation
Valerie Etzrodt, Temitayo O. Idowu, Heiko Schenk, Benjamin Seeliger, Antje Prasse, Kristina Thamm, Thorben Pape, Janina Müller-Deile, Matijs van Meurs, Thomas Thum, Ankita Garg, Robert Geffers, Klaus Stahl, Samir M. Parikh, Hermann Haller, Sascha David
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Use and impact of high intensity treatments in patients with traumatic brain injury across Europe: a CENTER-TBI analysis
Jilske A. Huijben, Abhishek Dixit, Nino Stocchetti, Andrew I. R. Maas, Hester F. Lingsma, Mathieu van der Jagt, David Nelson, Giuseppe Citerio, Lindsay Wilson, David K. Menon, Ari Ercole, the CENTER-TBI investigators and participants
01.12.2021 | COVID-19 | Research | Ausgabe 1/2021
Open Access
Helmet CPAP to treat hypoxic pneumonia outside the ICU: an observational study during the COVID-19 outbreak
Andrea Coppadoro, Annalisa Benini, Robert Fruscio, Luisa Verga, Paolo Mazzola, Giuseppe Bellelli, Marco Carbone, Giacomo Mulinacci, Alessandro Soria, Beatrice Noè, Eduardo Beck, Riccardo Di Sciacca, Davide Ippolito, Giuseppe Citerio, Maria Grazia Valsecchi, Andrea Biondi, Alberto Pesci, Paolo Bonfanti, Davide Gaudesi, Giacomo Bellani, Giuseppe Foti
01.12.2021 | COVID-19 | Research | Ausgabe 1/2021
Open Access
Computed tomography assessment of PEEP-induced alveolar recruitment in patients with severe COVID-19 pneumonia
Lorenzo Ball, Chiara Robba, Lorenzo Maiello, Jacob Herrmann, Sarah E. Gerard, Yi Xin, Denise Battaglini, Iole Brunetti, Giuseppe Minetti, Sara Seitun, Antonio Vena, Daniele Roberto Giacobbe, Matteo Bassetti, Patricia R. M. Rocco, Maurizio Cereda, Lucio Castellan, Nicolò Patroniti, Paolo Pelosi, GECOVID (GEnoa COVID-19) group
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Predicting neurological outcome after out-of-hospital cardiac arrest with cumulative information; development and internal validation of an artificial neural network algorithm
Peder Andersson, Jesper Johnsson, Ola Björnsson, Tobias Cronberg, Christian Hassager, Henrik Zetterberg, Pascal Stammet, Johan Undén, Jesper Kjaergaard, Hans Friberg, Kaj Blennow, Gisela Lilja, Matt P. Wise, Josef Dankiewicz, Niklas Nielsen, Attila Frigyesi
01.12.2021 | Research | Ausgabe 1/2021
Open Access
Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts
Yasser Sakr, Bruno François, Jordi Solé-Violan, Katarzyna Kotfis, Ulrich Jaschinski, Angel Estella, Marc Leone, Stephan M. Jakob, Xavier Wittebole, Luis E. Fontes, Miguel de Melo Gurgel, Thais Midega, Jean-Louis Vincent, V. Marco Ranieri, the SOAP and ICON Investigators
