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Current Hematologic Malignancy Reports

Current Hematologic Malignancy Reports OnlineFirst articles

18.03.2019 | Acute Lymphocytic Leukemias (K Ballen and M Keng, Section Editors)

Relapsed T Cell ALL: Current Approaches and New Directions

T cell acute lymphoblastic leukemia (T-ALL) accounts for approximately 15% of ALL cases and is twice as common in males than females [ 1 ]. Historically, newly diagnosed T-ALL was associated with substantially worse outcomes compared to B cell ALL …


Recent Advances in Adult Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) is an aggressive neoplasm of lymphoid progenitor cells. The annual incidence of ALL is 1.7 cases per 100,000 people in the USA [ 1 ]. In 2018, the estimated number of new cases was 5960 and the estimated number of …

08.03.2019 | T-Cell and Other Lymphoproliferative Malignancies (J Zain, Section Editor)

Development and Significance of Mouse Models in Lymphoma Research

Research into the molecular mechanisms of cancer pathogenesis and progression and the discovery of novel anti-cancer therapeutics has long relied on the evolution and use of animal models. From drosophila, zebrafish, canine, feline, equine …

04.03.2019 | Stem Cell Transplantation (R Maziarz, Section Editor) Open Access

Autologous Haematopoietic Stem Cell Transplantation in Multiple Sclerosis: a Review of Current Literature and Future Directions for Transplant Haematologists and Oncologists

Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS). MS typically presents as a relapsing-remitting illness. A relapse is a discrete, self-limiting episode of neurological dysfunction, which is caused by …

28.02.2019 | Multiple Myeloma (P Kapoor, Section Editor)

Challenges and Strategies in the Management of Multiple Myeloma in the Elderly Population

Multiple myeloma (MM) is a plasma cell proliferative disorder, accounting for approximately 1.8% of all newly diagnosed malignancies in the USA [ 1 ]. The median age at diagnosis of MM is 69 years, with approximately two-thirds of the patients …

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Current Hematologic Malignancy Reports provides in-depth review articles contributed by international experts on the most significant developments in the field. By presenting clear, insightful, balanced reviews that emphasize recently published papers of major importance, the journal elucidates current and emerging approaches to the diagnosis, treatment, management, and prevention of conditions associated with hematologic malignancy.

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