Erschienen in:
04.01.2018 | Breast
Does patient age affect the PPV3 of ACR BI-RADS Ultrasound categories 4 and 5 in the diagnostic setting?
verfasst von:
Yue Hu, Yaping Yang, Ran Gu, Liang Jin, Shiyu Shen, Fengtao Liu, Hongli Wang, Jingsi Mei, Xiaofang Jiang, Qiang Liu, Fengxi Su
Erschienen in:
European Radiology
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Ausgabe 6/2018
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Abstract
Objectives
To calculate the positive predictive value of biopsies performed (PPV3) of the Ultrasound section of the American College of Radiology Breast Imaging Reporting and Data System (ACR BI-RADS US) atlas categories 4 and 5 in different age groups and to determine whether patient age influences the PPV3 of each category in the diagnosis of breast lesions.
Methods
We identified 2,433 ACR BI-RADS US categories 4 and 5 lesions with a known pathological diagnosis in 2,433 women. The patients were classified into three age groups (<35, 35–50, and >50 years). The age-related PPV3 of each category in the three age groups were calculated based on the pathological diagnoses and compared using the chi-squared test.
Results
The overall PPV3 of each category was within the reference range provided by the ACR in 2013. PPV3 gradually increased with increasing age in patients with category 4 lesions. PPV3 in the oldest group with subcategories 4A and 4B lesions were close to or exceeded the reference values.
Conclusions
PPV3 and age were significantly associated in patients with category 4 lesions according to the newest edition of ACR BI-RADS US in the diagnostic setting. Closer attention should be given to older patients when assigning a final assessment category.
Key points
• In patients with category 4 lesions , the likelihood of malignancy is associated with age.
• In patients with category 5 lesions, the association is not definite.
• Closer attention should be given to older patients in applying the ACR BI-RADS US.