Skip to main content
Erschienen in: Surgical and Radiologic Anatomy 9/2020

07.05.2020 | Original Article

Evaluation of olfactory bulbus volume and olfactory sulcus depth by 3 T MR

verfasst von: Neşat Çullu, İbrahim Önder Yeniçeri, Bünyamin Güney, Murat Yunus Özdemir, İlkay Koşar

Erschienen in: Surgical and Radiologic Anatomy | Ausgabe 9/2020

Einloggen, um Zugang zu erhalten

Abstract

Objective

The aim of this study was to evaluate olfactory bulbus volume (OBV) and olfactory sulcus depth (OSD) according to age and sex with 3 T MRI in a healthy Turkish population.

Materials and methods

In the current study, 200 patients who had cranial MRI were retrospectively evaluated. They were divided into the following groups to examine the effects of age: group 1: 18–30 years old; group 2: 31–40 years old; group 3: 41–50 years old; group 4: 51–60 years old; and group 5: >60 years old. OBV and OSD measurements were performed on coronal T2-weighted brain MR images. The mean right and left olfactory bulb volume and sulcus depths were used for evaluation.

Results

The mean age was 46.5 ± 18.1 (range 18-86) years. The mean OBV value of both sides was 91.17 ± 7.8 mm 3 in all patients. The mean OSD value of both sides was 8.62 ± 0.84 mm in all patients. There was no statistically significant difference in OBV and OSD between sexes (P < 0.236; P < 0.482). Group 5 (>60 years old) was found to have significantly lower OBV and OSD values than the other groups (all P < 0.001).

Conclusion

The normal values of OBV and OSD should be established according to age to determine decreased OBV and OSD values.
Literatur
1.
Zurück zum Zitat Asal N, Muluk NB, Inal M, Şahan MH, Doğan A, Buturak SV (2018) Olfactory bulbus volume and olfactory sulcus depth in psychotic patients and patients with anxiety disorder/depression. Eur Arch Otorhinolaryngol 275:3017–3024CrossRef Asal N, Muluk NB, Inal M, Şahan MH, Doğan A, Buturak SV (2018) Olfactory bulbus volume and olfactory sulcus depth in psychotic patients and patients with anxiety disorder/depression. Eur Arch Otorhinolaryngol 275:3017–3024CrossRef
2.
Zurück zum Zitat Attems J, Walker L, Jellinger KA (2015) Olfaction and aging: a mini-review. Gerontology 61:485–490CrossRef Attems J, Walker L, Jellinger KA (2015) Olfaction and aging: a mini-review. Gerontology 61:485–490CrossRef
3.
Zurück zum Zitat Buschhüter D, Smitka M, Psuchmann S et al (2008) Correlation between olfactory bulb volume and olfactory function. Neuroimage 42:498–502CrossRef Buschhüter D, Smitka M, Psuchmann S et al (2008) Correlation between olfactory bulb volume and olfactory function. Neuroimage 42:498–502CrossRef
4.
Zurück zum Zitat Chung MS, Choi WR, Jeong HY, Lee JH, Kim JH (2018) MRI maging-based evaluations of olfactory bulb atrophy in patients with olfactory dysfunction. Am J Neuroradiol 39:532–537CrossRef Chung MS, Choi WR, Jeong HY, Lee JH, Kim JH (2018) MRI maging-based evaluations of olfactory bulb atrophy in patients with olfactory dysfunction. Am J Neuroradiol 39:532–537CrossRef
5.
Zurück zum Zitat Doğan A, Muluk NB, Asal N, Şahan MH, Inal M, Gündüz Ö, Arıkan OK (2018) Olfactory bulb volume and olfactory sulcus depth in patients with Behçet’s diseas. J Laryngol Otol 132:1088–1092CrossRef Doğan A, Muluk NB, Asal N, Şahan MH, Inal M, Gündüz Ö, Arıkan OK (2018) Olfactory bulb volume and olfactory sulcus depth in patients with Behçet’s diseas. J Laryngol Otol 132:1088–1092CrossRef
6.
Zurück zum Zitat Hang W, Liu G, Han T, Zhang J, Zhang Q (2015) A correlation study on olfactory bulb volumes with ages and olfactory function in healthy adults. Chinese J Otorhinolaryngol Head Neck Surg 50:744–748 Hang W, Liu G, Han T, Zhang J, Zhang Q (2015) A correlation study on olfactory bulb volumes with ages and olfactory function in healthy adults. Chinese J Otorhinolaryngol Head Neck Surg 50:744–748
7.
Zurück zum Zitat Held P, Seitz J, Fründ R, Nitz WR, Haffke T, Hees H, Bonkowsky V (2000) MRI detection of olfactory bulb and tract. J Neuroradiol 27:112–118PubMed Held P, Seitz J, Fründ R, Nitz WR, Haffke T, Hees H, Bonkowsky V (2000) MRI detection of olfactory bulb and tract. J Neuroradiol 27:112–118PubMed
8.
Zurück zum Zitat Hummel T, Urbig A, Huart C, Duprez T, Rombaux P (2015) Volume of olfactory bulb and depth of olfactory sulcus in 378 consecutive patients with olfactory loss. J Neurol 262:1046–1051CrossRef Hummel T, Urbig A, Huart C, Duprez T, Rombaux P (2015) Volume of olfactory bulb and depth of olfactory sulcus in 378 consecutive patients with olfactory loss. J Neurol 262:1046–1051CrossRef
9.
Zurück zum Zitat Hummel T, Smitka M, Puschmann S, Gerber JC, Schaal B, Buschhüter D (2011) Correlation between olfactory bulb volume and olfactory function in children and adolescents. Exp Brain Res 214:285–291CrossRef Hummel T, Smitka M, Puschmann S, Gerber JC, Schaal B, Buschhüter D (2011) Correlation between olfactory bulb volume and olfactory function in children and adolescents. Exp Brain Res 214:285–291CrossRef
10.
Zurück zum Zitat Kass MD, Czarnecki LA, McGann JP (2018) Stable olfactory sensory neuron in vivo physiology during normal aging. Neurobiol Aging 69:33–37CrossRef Kass MD, Czarnecki LA, McGann JP (2018) Stable olfactory sensory neuron in vivo physiology during normal aging. Neurobiol Aging 69:33–37CrossRef
11.
Zurück zum Zitat Leboucq N, Champfleur N, Champfleur S, Bonafé A (2013) The olfactory systems. Diagn Int Imaging 94:985–991CrossRef Leboucq N, Champfleur N, Champfleur S, Bonafé A (2013) The olfactory systems. Diagn Int Imaging 94:985–991CrossRef
12.
Zurück zum Zitat Mueller A, Rodewald A, Reden J, Gerber J, von Kummer R, Hummel T (2005) Reduced olfactory bulb volume in post-traumatic and post-infectious olfactory dysfunction. Neuro Report 16:475–478 Mueller A, Rodewald A, Reden J, Gerber J, von Kummer R, Hummel T (2005) Reduced olfactory bulb volume in post-traumatic and post-infectious olfactory dysfunction. Neuro Report 16:475–478
13.
Zurück zum Zitat Paschen L, Schmidt N, Wolff S, Cnyrim C, van Eimeren T, Zeuner KE, Deuschl G, Witt K (2015) The olfactory bulb volume in patients with idiopathic Parkinson’s disease. Eur J Neurol 22:1068–1073CrossRef Paschen L, Schmidt N, Wolff S, Cnyrim C, van Eimeren T, Zeuner KE, Deuschl G, Witt K (2015) The olfactory bulb volume in patients with idiopathic Parkinson’s disease. Eur J Neurol 22:1068–1073CrossRef
14.
Zurück zum Zitat Rombaux Ph, Duprez T, Hummel T (2009) Olfactory bulb volume in the clinical assessment of olfactory dysfunction. Rhinology 47:3–9PubMed Rombaux Ph, Duprez T, Hummel T (2009) Olfactory bulb volume in the clinical assessment of olfactory dysfunction. Rhinology 47:3–9PubMed
15.
Zurück zum Zitat Rottstaedt F, Weidner K, Hummel T, Croy I (2018) Pre-aging of the olfactory bulb in major depression with high comorbidity of mental disorders. Front Aging Neurosci 10:354CrossRef Rottstaedt F, Weidner K, Hummel T, Croy I (2018) Pre-aging of the olfactory bulb in major depression with high comorbidity of mental disorders. Front Aging Neurosci 10:354CrossRef
16.
Zurück zum Zitat Seubert J, Freiherr J, Frasnelli J, Hummel T, Lundström JN (2013) Orbitofrontal cortex and olfactory bulb volume predict distinct aspects of olfactory performance in healthy subjects. Cereb Cortex 23:2448–2456CrossRef Seubert J, Freiherr J, Frasnelli J, Hummel T, Lundström JN (2013) Orbitofrontal cortex and olfactory bulb volume predict distinct aspects of olfactory performance in healthy subjects. Cereb Cortex 23:2448–2456CrossRef
17.
Zurück zum Zitat Wang JH, You JF, Liu DF, Ni DF, Zhang ZX, Guan J (2011) Association of olfactory bulb volume and olfactory sulcus depth with olfactory function in patients with parkinson disease. Am J Neuroradiol 32:677–681CrossRef Wang JH, You JF, Liu DF, Ni DF, Zhang ZX, Guan J (2011) Association of olfactory bulb volume and olfactory sulcus depth with olfactory function in patients with parkinson disease. Am J Neuroradiol 32:677–681CrossRef
18.
Zurück zum Zitat Wang J, You H, Zhang ZX, Guan J, Chen XM, Liu JF, Yang DH, Shang YY, Zhu YY, Zou QJ, Gao ZQ, Ni DF (2009) MRI features of olfactory bulb volume in healthy middle and oldaged persons. Chinese J Otorhinolaryngol Head Neck Surg 44:1006–1009 Wang J, You H, Zhang ZX, Guan J, Chen XM, Liu JF, Yang DH, Shang YY, Zhu YY, Zou QJ, Gao ZQ, Ni DF (2009) MRI features of olfactory bulb volume in healthy middle and oldaged persons. Chinese J Otorhinolaryngol Head Neck Surg 44:1006–1009
19.
Zurück zum Zitat Yu H, Hang W, Zhang J, Liu G (2015) Olfactory function in patients with Alzheimer’ disease. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 29:444–447PubMed Yu H, Hang W, Zhang J, Liu G (2015) Olfactory function in patients with Alzheimer’ disease. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 29:444–447PubMed
20.
Zurück zum Zitat Zhang Q, Liu G, Hang W (2014) Olfactory bulb volume and depth of olfactory sulcus in patients with allergic rhinitis. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 28:1956–1960PubMed Zhang Q, Liu G, Hang W (2014) Olfactory bulb volume and depth of olfactory sulcus in patients with allergic rhinitis. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 28:1956–1960PubMed
Metadaten
Titel
Evaluation of olfactory bulbus volume and olfactory sulcus depth by 3 T MR
verfasst von
Neşat Çullu
İbrahim Önder Yeniçeri
Bünyamin Güney
Murat Yunus Özdemir
İlkay Koşar
Publikationsdatum
07.05.2020
Verlag
Springer Paris
Erschienen in
Surgical and Radiologic Anatomy / Ausgabe 9/2020
Print ISSN: 0930-1038
Elektronische ISSN: 1279-8517
DOI
https://doi.org/10.1007/s00276-020-02484-w

Weitere Artikel der Ausgabe 9/2020

Surgical and Radiologic Anatomy 9/2020 Zur Ausgabe

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

S3-Leitlinie zu Pankreaskrebs aktualisiert

23.04.2024 Pankreaskarzinom Nachrichten

Die Empfehlungen zur Therapie des Pankreaskarzinoms wurden um zwei Off-Label-Anwendungen erweitert. Und auch im Bereich der Früherkennung gibt es Aktualisierungen.

Fünf Dinge, die im Kindernotfall besser zu unterlassen sind

18.04.2024 Pädiatrische Notfallmedizin Nachrichten

Im Choosing-Wisely-Programm, das für die deutsche Initiative „Klug entscheiden“ Pate gestanden hat, sind erstmals Empfehlungen zum Umgang mit Notfällen von Kindern erschienen. Fünf Dinge gilt es demnach zu vermeiden.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.