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01.08.2010 | Head and Neck

Evaluation of real-time qualitative sonoelastography of focal lesions in the parotid and submandibular glands: applications and limitations

verfasst von: Kunwar S. S. Bhatia, Darshana D. Rasalkar, Yim-Ping Lee, Ka-Tak Wong, Ann D. King, Hok-Yuen Yuen, Anil T. Ahuja

Erschienen in: European Radiology | Ausgabe 8/2010

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Abstract

Objective

To evaluate qualitative ultrasound elastography for focal salivary gland masses identified during routine clinical practice.

Methods

Sixty-five parotid or submandibular masses in 61 patients underwent real-time qualitative ultrasound elastography and were scored on colour-scaled elastograms in terms of their stiffness relative to adjacent normal salivary parenchyma from ES 1 (soft) to ES 4 (stiff). This was correlated with diagnosis from aspiration cytology or histology.

Results

There were 29 Warthin’s tumours (WTs), 23 pleomorphic adenomas (PAs), 2 adenoid cystic carcinomas, 1 adenosquamous carcinoma, 1 nodal metastasis from nasopharyngeal carcinoma, 1 lymphoma (2 deposits), 3 Kuttner tumours and 4 cases of Kimura’s disease. ES scores showed clustering according to pathological condition. In this respect, PAs were firmer than WTs (P < 0.004, Fisher’s exact test). Nine, 19, 14 and 17 of the benign masses and 0, 1, 2 and 3 of the malignant masses were ES 1, 2, 3 and 4 respectively. All three primary salivary malignancies were ES 4 compared with 1/29 WTs and 16/23 PAs.

Conclusion

These preliminary findings suggest that qualitative real-time ultrasound elastography, although an ancillary technique to conventional ultrasound in the salivary glands, is likely to have a poor ability to discriminate benign lesions (particularly PAs) from malignant disease.

Alam F, Naito K, Horiguchi J, Fukuda H, Tachikake T, Ito K (2008) Accuracy of sonographic elastography in the differential diagnosis of enlarged cervical lymph nodes: comparison with conventional B-mode sonography. AJR Am J Roentgenol 191:604–610. doi:10.2214/AJR.07.3401 CrossRefPubMed

Garra BS (2007) Imaging and estimation of tissue elasticity by ultrasound. Ultrasound Q 23:255–268. doi:10.1097/ruq.0b013e31815b7ed6 CrossRefPubMed

Itoh A, Ueno E, Tohno E et al (2006) Breast disease: clinical application of US elastography for diagnosis. Radiology 239:341–350. doi:10.1148/radiol.2391041676 CrossRefPubMed

Janssen J, Schlorer E, Greiner L (2007) EUS elastography of the pancreas: feasibility and pattern description of the normal pancreas, chronic pancreatitis, and focal pancreatic lesions. Gastrointest Endosc 65:971–978. doi:10.1016/j.gie.2006.12.057 CrossRefPubMed

Lyshchik A, Higashi T, Asato R et al (2007) Cervical lymph node metastases: diagnosis at sonoelastography–initial experience. Radiology 243:258–267. doi:10.1148/radiol.2431052032 CrossRefPubMed

Saftoiu A, Vilmann P, Hassan H, Gorunescu F (2006) Analysis of endoscopic ultrasound elastography used for characterisation and differentiation of benign and malignant lymph nodes. Ultraschall Med 27:535–542. doi:10.1055/s-2006–927117 CrossRefPubMed

Taylor LS, Rubens DJ, Porter BC et al (2005) Prostate cancer: three-dimensional sonoelastography for in vitro detection. Radiology 237:981–985. doi:10.1148/radiol.2373041573 CrossRefPubMed

Thomas A, Kummel S, Gemeinhardt O, Fischer T (2007) Real-time sonoelastography of the cervix: tissue elasticity of the normal and abnormal cervix. Acad Radiol 14:193–200. doi:10.1016/j.acra.2006.11.010 CrossRefPubMed

Zhi H, Ou B, Luo BM, Feng X, Wen YL, Yang HY (2007) Comparison of ultrasound elastography, mammography, and sonography in the diagnosis of solid breast lesions. J Ultrasound Med 26:807–815PubMed

10.

Asteria C, Giovanardi A, Pizzocaro A et al (2008) US-elastography in the differential diagnosis of benign and malignant thyroid nodules. Thyroid 18:523–531. doi:10.1089/thy.2007.0323 CrossRefPubMed

11.

Hong Y, Liu X, Li Z, Zhang X, Chen M, Luo Z (2009) Real-time ultrasound elastography in the differential diagnosis of benign and malignant thyroid nodules. J Ultrasound Med 28:861–867PubMed

12.

Lyshchik A, Higashi T, Asato R et al (2005) Thyroid gland tumour diagnosis at US elastography. Radiology 237:202–211. doi:10.1148/radiol.2363041248 CrossRefPubMed

13.

Rago T, Santini F, Scutari M, Pinchera A, Vitti P (2007) Elastography: new developments in ultrasound for predicting malignancy in thyroid nodules. J Clin Endocrinol Metab 92:2917–2922. doi:10.1210/jc.2007–0641 CrossRefPubMed

14.

Dimitriu D (2008) Ultrasound elastography features of major salivary gland tumours. Radiological Society of North America 94th scientific assembly and annual meeting, Chicago. Abstract available via http://www.hitachi-medical-systems.eu/fileadmin/hitachi/onPage/hi-rte/lymph_nodes.pdf. Accessed 16 December 2009

15.

Ahuja AT, Evans R, Vlantis AC (2003) Salivary gland cancer. In: Ahuja A (ed) Imaging in head and neck cancer: apractical approach. Greenwich Medical Media, London, pp 114–142

16.

Ahuja AT, Richards PS, Wong KT et al (2003) Kuttner tumour (chronic sclerosing sialadenitis) of the submandibular gland: sonographic appearances. Ultrasound Med Biol 29:913–919CrossRefPubMed

17.

Ching AS, Tsang WM, Ahuja AT, Metreweli C (2002) Extranodal manifestation of Kimura's disease: ultrasound features. Eur Radiol 12:600–604. doi:10.1007/s003300100961 PubMed

18.

Ahuja AT, Loke TK, Mok CO, Chow LT, Metreweli C (1995) Ultrasound of Kimura's disease. Clin Radiol 50:170–173CrossRefPubMed

19.

Gritzmann N, Rettenbacher T, Hollerweger A, Macheiner P, Hubner E (2003) Sonography of the salivary glands. Eur Radiol 13:964–975. doi:10.1007/s00330–002–1586–9 PubMed

20.

Som PM, Brandwein MS (2003) Salivary glands: anatomy and pathology. In: Som PM, Brandwein M (eds) Head and neck imaging. Mosby, St. Louis, pp 2005–2133

21.

Bozzato A, Zenk J, Greess H et al (2007) Potential of ultrasound diagnosis for parotid tumours: analysis of qualitative and quantitative parameters. Otolaryngol Head Neck Surg 137:642–646. doi:10.1016/j.otohns.2007.05.062 CrossRefPubMed

22.

Torske K (2006) Benign neoplasms of the salivary glands. In: Thompson LDR (ed) Head and neck pathology. Churchill Livingstone, Philadelphia, pp 295–320

23.

Gnepp DR, Brandwein MS, Henley JD (2001) Salivary and lacrimal glands. In: Gnepp DR (ed) Diagnostic and surgical pathology of the head and neck. W.B. Saunders Company, Philadelphia, pp 325–430

24.

Stewart CJ, MacKenzie K, McGarry GW, Mowat A (2000) Fine-needle aspiration cytology of salivary gland: a review of 341 cases. Diagn Cytopathol 22:139–146. doi:10.1002/(SICI)1097–0339(20000301)22:3<139::AID-DC2>3.0.CO;2-A CrossRefPubMed

25.

Klijanienko J, Vielh P (1997) Fine-needle sampling of salivary gland lesions. IV. Review of 50 cases of mucoepidermoid carcinoma with histologic correlation. Diagn Cytopathol 17:92–98. doi:10.1002/(SICI)1097–0339(199708)17:2<92::AID-DC3>3.0.CO;2-Q CrossRefPubMed

26.

Frable MA, Frable WJ (1991) Fine-needle aspiration biopsy of salivary glands. Laryngoscope 101:245–249. doi:10.1288/00005537–199103000–00005 CrossRefPubMed

27.

Cohen MB, Reznicek MJ, Miller TR (1992) Fine-needle aspiration biopsy of the salivary glands. Pathol Annu 27(Pt 2):213–245PubMed

28.

Jayaram G, Verma AK, Sood N, Khurana N (1994) Fine needle aspiration cytology of salivary gland lesions. J Oral Pathol Med 23:256–261CrossRefPubMed

29.

Verma K, Kapila K (2002) Role of fine needle aspiration cytology in diagnosis of pleomorphic adenomas. Cytopathology 13:121–127CrossRefPubMed

30.

Dighe M, Bae U, Richardson ML, Dubinsky TJ, Minoshima S, Kim Y (2008) Differential diagnosis of thyroid nodules with US elastography using carotid artery pulsation. Radiology 248:662–669. doi:10.1148/radiol.2482071758 CrossRefPubMed

Titel: Evaluation of real-time qualitative sonoelastography of focal lesions in the parotid and submandibular glands: applications and limitations
verfasst von: Kunwar S. S. Bhatia
Darshana D. Rasalkar
Yim-Ping Lee
Ka-Tak Wong
Ann D. King
Hok-Yuen Yuen
Anil T. Ahuja
Publikationsdatum: 01.08.2010
Verlag: Springer-Verlag
Erschienen in: European Radiology / Ausgabe 8/2010
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-010-1756-0

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Evaluation of real-time qualitative sonoelastography of focal lesions in the parotid and submandibular glands: applications and limitations