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01.07.2014 | Cardiac

Feasibility of prospectively ECG-triggered high-pitch coronary CT angiography with 30 mL iodinated contrast agent at 70 kVp: initial experience

verfasst von: Long Jiang Zhang, Li Qi, Jing Wang, Chun Xiang Tang, Chang Sheng Zhou, Xue Man Ji, James V. Spearman, Carlo Nicola De Cecco, Felix G. Meinel, U. Joseph Schoepf, Guang Ming Lu

Erschienen in: European Radiology | Ausgabe 7/2014

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Abstract

Objectives

To evaluate the feasibility, image quality and radiation dose of prospectively ECG-triggered high-pitch coronary CT angiography (CCTA) with 30 mL contrast agent at 70 kVp.

Methods

Fifty-eight patients with suspected coronary artery disease, a body mass index (BMI) of less than 25 kg/m², sinus rhythm and a heart rate (HR) of less than 70 beats per minute (bpm) were prospectively enrolled in this study. Thirty mL of 370 mg I/mL iodinated contrast agent was administrated at a flow rate of 5 mL/s. All patients underwent prospectively ECG-triggered high-pitch CCTA on a second-generation dual-source CT system at 70 kVp using automated tube current modulation.

Results

Fifty-six patients (96.6 %) had diagnostic CCTA images and two patients (3.4 %) had one vessel with poor image quality each rated as non-diagnostic. No significant effects of HR, HR variability and BMI on CCTA image quality were observed (all P > 0.05). Effective dose was 0.17 ± 0.02 mSv and the size-specific dose estimate was 1.03 ± 0.13 mGy.

Conclusion

Prospectively ECG-triggered high-pitch CCTA at 70 kVp with 30 mL of contrast agent can provide diagnostic image quality at a radiation dose of less than 0.2 mSv in patients with a BMI of less than 25 kg/m² and an HR of less than 70 bpm.

Key points

• Prospectively ECG-triggered high-pitch CCTA at 70 kVp/30 mL contrast agent is feasible.

• Diagnostic image quality can be obtained at a radiation dose of less than 0.2 mSv.

• This protocol is suitable for normal-weight patients with slow heart rate.

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Titel: Feasibility of prospectively ECG-triggered high-pitch coronary CT angiography with 30 mL iodinated contrast agent at 70 kVp: initial experience
verfasst von: Long Jiang Zhang
Li Qi
Jing Wang
Chun Xiang Tang
Chang Sheng Zhou
Xue Man Ji
James V. Spearman
Carlo Nicola De Cecco
Felix G. Meinel
U. Joseph Schoepf
Guang Ming Lu
Publikationsdatum: 01.07.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 7/2014
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-014-3157-2

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Feasibility of prospectively ECG-triggered high-pitch coronary CT angiography with 30 mL iodinated contrast agent at 70 kVp: initial experience