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Erschienen in: European Radiology 5/2021

13.10.2020 | Emergency Radiology

Imaging strategies for patients with suspicion of uncomplicated colic pain: diagnostic accuracy and management assessment

verfasst von: Claire Faget, Ingrid Millet, Mustapha Sebbane, Rodolphe Thuret, Cécile Verheyden, Fernanda Curros-Doyon, Nicolas Molinari, Patrice Taourel

Erschienen in: European Radiology | Ausgabe 5/2021

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Abstract

Objective

Compare different imaging scenarios in the diagnosis of uncomplicated renal colic due to urolithiasis (URCU).

Materials and methods

A total of 206 prospectively included patients had been admitted with suspected URCU and had undergone abdominal plain film (APF), US and unenhanced CT after clinical STONE score evaluation. CT was the reference standard. We assessed sensitivity (Se), specificity (Spe) and Youden index for colic pain diagnosis, percentage of patients managed by urologic treatment with stone identified, percentage of alternative diagnoses (AD) and exposure to radiation, according to single imaging approaches, strategies driven by patient characteristics and conditional imaging strategies after APF and US.

Results

One hundred (48.5%) patients had a final diagnosis of URCU and 19 underwent urologic treatment. The conditional strategy, i.e. CT in patients who had no stone identified at US, had a perfect sensitivity and specificity. This enabled diagnosis of all stones requiring urology management while decreasing the number of CT exams by 22%. The strategy whereby CT was used when there was neither direct or indirect APF + US finding of colic pain nor alternative diagnoses in patients with a STONE score ≥ 10 had a sensitivity of 0.95 and a specificity of 0.99, identified 84% of stones managed by urologic treatment and decreased the number of CT examinations by 76%.

Conclusion

In patients with clinical findings consistent with URCU, the use of ultrasound as first-line imaging modality, with CT restricted to patients with negative US and a STONE score ≥ 10, led to a sensitivity and specificity of above 95%, identified 84% of stones requiring urological management and reduced the number of CT scans needed by fourfold.

Key Points

• For diagnosis, the use of APF + US as first-line imaging, with CT restricted to patients with both a normal APF + US and a STONE score ≥ 10, provides both a sensitivity and specificity superior or equal to 95% and reduces the number of CT scans necessary by fourfold.
• For management, the use of APF + US as first-line imaging, with CT restricted to patients with both a normal APF + US and a STONE score ≥ 10, maintains a 84% stone identification rate in urology-treated patients.
Literatur
1.
Zurück zum Zitat Fwu CW, Eggers PW, Kimmel PL, Kusek JW, Kirkali Z (2013) Emergency department visits, use of imaging, and drugs for urolithiasis have increased in the United States. Kidney Int 83:479–486CrossRef Fwu CW, Eggers PW, Kimmel PL, Kusek JW, Kirkali Z (2013) Emergency department visits, use of imaging, and drugs for urolithiasis have increased in the United States. Kidney Int 83:479–486CrossRef
2.
Zurück zum Zitat Smith RC, Verga M, McCarthy S, Rosenfield AT (1996) Diagnosis of acute flank pain: value of unenhanced helical CT. AJR Am J Roentgenol 166:97–101CrossRef Smith RC, Verga M, McCarthy S, Rosenfield AT (1996) Diagnosis of acute flank pain: value of unenhanced helical CT. AJR Am J Roentgenol 166:97–101CrossRef
3.
Zurück zum Zitat Coursey CA, Casalino DD, Remer EM et al (2012) ACR appropriateness criteria(R) acute onset flank pain--suspicion of stone disease. Ultrasound Q 28:227–233CrossRef Coursey CA, Casalino DD, Remer EM et al (2012) ACR appropriateness criteria(R) acute onset flank pain--suspicion of stone disease. Ultrasound Q 28:227–233CrossRef
4.
Zurück zum Zitat Westphalen AC, Hsia RY, Maselli JH, Wang R, Gonzales R (2011) Radiological imaging of patients with suspected urinary tract stones: national trends, diagnoses, and predictors. Acad Emerg Med 18:699–707CrossRef Westphalen AC, Hsia RY, Maselli JH, Wang R, Gonzales R (2011) Radiological imaging of patients with suspected urinary tract stones: national trends, diagnoses, and predictors. Acad Emerg Med 18:699–707CrossRef
5.
Zurück zum Zitat Lumbreras B, Donat L, Hernandez-Aguado I (2010) Incidental findings in imaging diagnostic tests: a systematic review. Br J Radiol 83:276–289CrossRef Lumbreras B, Donat L, Hernandez-Aguado I (2010) Incidental findings in imaging diagnostic tests: a systematic review. Br J Radiol 83:276–289CrossRef
7.
Zurück zum Zitat Poletti PA, Platon A, Rutschmann OT, Schmidlin FR, Iselin CE, Becker CD (2007) Low-dose versus standard-dose CT protocol in patients with clinically suspected renal colic. AJR Am J Roentgenol 188:927–933CrossRef Poletti PA, Platon A, Rutschmann OT, Schmidlin FR, Iselin CE, Becker CD (2007) Low-dose versus standard-dose CT protocol in patients with clinically suspected renal colic. AJR Am J Roentgenol 188:927–933CrossRef
8.
Zurück zum Zitat Fowler KA, Locken JA, Duchesne JH, Williamson MR (2002) US for detecting renal calculi with nonenhanced CT as a reference standard. Radiology 222:109–113CrossRef Fowler KA, Locken JA, Duchesne JH, Williamson MR (2002) US for detecting renal calculi with nonenhanced CT as a reference standard. Radiology 222:109–113CrossRef
9.
Zurück zum Zitat Catalano O, Nunziata A, Altei F, Siani A (2002) Suspected ureteral colic: primary helical CT versus selective helical CT after unenhanced radiography and sonography. AJR Am J Roentgenol 178:379–387CrossRef Catalano O, Nunziata A, Altei F, Siani A (2002) Suspected ureteral colic: primary helical CT versus selective helical CT after unenhanced radiography and sonography. AJR Am J Roentgenol 178:379–387CrossRef
10.
Zurück zum Zitat Smith-Bindman R, Aubin C, Bailitz J et al (2014) Ultrasonography versus computed tomography for suspected nephrolithiasis. N Engl J Med 371:1100–1110CrossRef Smith-Bindman R, Aubin C, Bailitz J et al (2014) Ultrasonography versus computed tomography for suspected nephrolithiasis. N Engl J Med 371:1100–1110CrossRef
11.
Zurück zum Zitat Moore CL, Bomann S, Daniels B et al (2014) Derivation and validation of a clinical prediction rule for uncomplicated ureteral stone--the STONE score: retrospective and prospective observational cohort studies. BMJ 348:g2191CrossRef Moore CL, Bomann S, Daniels B et al (2014) Derivation and validation of a clinical prediction rule for uncomplicated ureteral stone--the STONE score: retrospective and prospective observational cohort studies. BMJ 348:g2191CrossRef
12.
Zurück zum Zitat Wang RC, Rodriguez RM, Moghadassi M et al (2016) External validation of the STONE score, a clinical prediction rule for ureteral stone: an observational multi-institutional study. Ann Emerg Med 67:423-432.e422 Wang RC, Rodriguez RM, Moghadassi M et al (2016) External validation of the STONE score, a clinical prediction rule for ureteral stone: an observational multi-institutional study. Ann Emerg Med 67:423-432.e422
13.
14.
Zurück zum Zitat Green SM, Schriger DL (2016) The sinking STONE: what a failed validation can teach us about clinical decision rules. Ann Emerg Med 67:433–436CrossRef Green SM, Schriger DL (2016) The sinking STONE: what a failed validation can teach us about clinical decision rules. Ann Emerg Med 67:433–436CrossRef
15.
Zurück zum Zitat Turk C, Petrik A, Sarica K et al (2016) EAU guidelines on diagnosis and conservative management of urolithiasis. Eur Urol 69:468–474CrossRef Turk C, Petrik A, Sarica K et al (2016) EAU guidelines on diagnosis and conservative management of urolithiasis. Eur Urol 69:468–474CrossRef
16.
Zurück zum Zitat Bredemeyer M (2016) ACR appropriateness criteria for acute onset of flank pain with suspicion of stone disease. Am Fam Physician 94:575–576PubMed Bredemeyer M (2016) ACR appropriateness criteria for acute onset of flank pain with suspicion of stone disease. Am Fam Physician 94:575–576PubMed
17.
Zurück zum Zitat Daniels B, Gross CP, Molinaro A et al (2016) STONE PLUS: evaluation of emergency department patients with suspected renal colic, using a clinical prediction tool combined with point-of-care limited ultrasonography. Ann Emerg Med 67:439–448CrossRef Daniels B, Gross CP, Molinaro A et al (2016) STONE PLUS: evaluation of emergency department patients with suspected renal colic, using a clinical prediction tool combined with point-of-care limited ultrasonography. Ann Emerg Med 67:439–448CrossRef
18.
Zurück zum Zitat Lukasiewicz A, Bhargavan-Chatfield M, Coombs L et al (2014) Radiation dose index of renal colic protocol CT studies in the United States: a report from the American College of Radiology National Radiology Data Registry. Radiology 271:445–451CrossRef Lukasiewicz A, Bhargavan-Chatfield M, Coombs L et al (2014) Radiation dose index of renal colic protocol CT studies in the United States: a report from the American College of Radiology National Radiology Data Registry. Radiology 271:445–451CrossRef
19.
Zurück zum Zitat Finnerty NM, Rodriguez RM, Carpenter CR et al (2015) Clinical decision rules for diagnostic imaging in the emergency department: a research agenda. Acad Emerg Med 22:1406–1416CrossRef Finnerty NM, Rodriguez RM, Carpenter CR et al (2015) Clinical decision rules for diagnostic imaging in the emergency department: a research agenda. Acad Emerg Med 22:1406–1416CrossRef
20.
Zurück zum Zitat Jendeberg J, Geijer H, Alshamari M, Cierzniak B, Liden M (2017) Size matters: the width and location of a ureteral stone accurately predict the chance of spontaneous passage. Eur Radiol 27:4775–4785CrossRef Jendeberg J, Geijer H, Alshamari M, Cierzniak B, Liden M (2017) Size matters: the width and location of a ureteral stone accurately predict the chance of spontaneous passage. Eur Radiol 27:4775–4785CrossRef
21.
Zurück zum Zitat Dropkin BM, Moses RA, Sharma D, Pais VM Jr (2015) The natural history of nonobstructing asymptomatic renal stones managed with active surveillance. J Urol 193:1265–1269CrossRef Dropkin BM, Moses RA, Sharma D, Pais VM Jr (2015) The natural history of nonobstructing asymptomatic renal stones managed with active surveillance. J Urol 193:1265–1269CrossRef
22.
Zurück zum Zitat Kim HY, Choe HS, Lee DS, Yoo JM, Lee SJ (2017) Transient renal impairment in the absence of pre-existing chronic kidney disease in patients with unilateral ureteric stone impaction. Urolithiasis 45:249–254 Kim HY, Choe HS, Lee DS, Yoo JM, Lee SJ (2017) Transient renal impairment in the absence of pre-existing chronic kidney disease in patients with unilateral ureteric stone impaction. Urolithiasis 45:249–254
23.
Zurück zum Zitat den Harder AM, Willemink MJ, van Doormaal PJ et al (2018) Radiation dose reduction for CT assessment of urolithiasis using iterative reconstruction: a prospective intra-individual study. Eur Radiol 28:143–150CrossRef den Harder AM, Willemink MJ, van Doormaal PJ et al (2018) Radiation dose reduction for CT assessment of urolithiasis using iterative reconstruction: a prospective intra-individual study. Eur Radiol 28:143–150CrossRef
24.
Zurück zum Zitat Albert JM (2013) Radiation risk from CT: implications for cancer screening. AJR Am J Roentgenol 201:W81–W87CrossRef Albert JM (2013) Radiation risk from CT: implications for cancer screening. AJR Am J Roentgenol 201:W81–W87CrossRef
26.
Zurück zum Zitat Nery DR, Costa YB, Mussi TC, Baroni RH (2018) Epidemiological and imaging features that can affect the detection of ureterolithiasis on ultrasound. Radiol Bras 51:287–292CrossRef Nery DR, Costa YB, Mussi TC, Baroni RH (2018) Epidemiological and imaging features that can affect the detection of ureterolithiasis on ultrasound. Radiol Bras 51:287–292CrossRef
27.
Zurück zum Zitat Schoenfeld EM, Poronsky KE, Elia TR, Budhram GR, Garb JL, Mader TJ (2015) Young patients with suspected uncomplicated renal colic are unlikely to have dangerous alternative diagnoses or need emergent intervention. West J Emerg Med 16:269–275CrossRef Schoenfeld EM, Poronsky KE, Elia TR, Budhram GR, Garb JL, Mader TJ (2015) Young patients with suspected uncomplicated renal colic are unlikely to have dangerous alternative diagnoses or need emergent intervention. West J Emerg Med 16:269–275CrossRef
28.
Zurück zum Zitat Gervaise A, Gervaise-Henry C, Pernin M, Naulet P, Junca-Laplace C, Lapierre-Combes M (2016) How to perform low-dose computed tomography for renal colic in clinical practice. Diagn Interv Imaging 97(4):393–400CrossRef Gervaise A, Gervaise-Henry C, Pernin M, Naulet P, Junca-Laplace C, Lapierre-Combes M (2016) How to perform low-dose computed tomography for renal colic in clinical practice. Diagn Interv Imaging 97(4):393–400CrossRef
29.
Zurück zum Zitat Masselli G, Derme M, Bernieri MG et al (2014) Stone disease in pregnancy: imaging-guided therapy. Insights Imaging 5:691–696CrossRef Masselli G, Derme M, Bernieri MG et al (2014) Stone disease in pregnancy: imaging-guided therapy. Insights Imaging 5:691–696CrossRef
30.
Zurück zum Zitat Moore CL, Carpenter CR, Heilbrun ML et al (2019) Imaging in suspected renal colic: systematic review of the literature and multispecialty consensus. J Urol 202(3):475–483CrossRef Moore CL, Carpenter CR, Heilbrun ML et al (2019) Imaging in suspected renal colic: systematic review of the literature and multispecialty consensus. J Urol 202(3):475–483CrossRef
31.
Zurück zum Zitat European Commission. European guidelines on quality criteria for computed tomography. Report EUR 16262. Brussels, Belgium: European Commission, 1999 European Commission. European guidelines on quality criteria for computed tomography. Report EUR 16262. Brussels, Belgium: European Commission, 1999
32.
Zurück zum Zitat (2007) The 2007 Recommendations of the International Commission on Radiological Protection. ICRP publication 103. Ann ICRP 37:1–332 (2007) The 2007 Recommendations of the International Commission on Radiological Protection. ICRP publication 103. Ann ICRP 37:1–332
33.
Zurück zum Zitat Schoenfeld EM, Pekow PS, Shieh MS, Scales CD Jr, Lagu T, Lindenauer PK (2017) The diagnosis and management of patients with renal colic across a sample of US hospitals: high CT utilization despite low rates of admission and inpatient urologic intervention. PLoS One 12:e0169160CrossRef Schoenfeld EM, Pekow PS, Shieh MS, Scales CD Jr, Lagu T, Lindenauer PK (2017) The diagnosis and management of patients with renal colic across a sample of US hospitals: high CT utilization despite low rates of admission and inpatient urologic intervention. PLoS One 12:e0169160CrossRef
34.
Zurück zum Zitat Thompson RJ, Wojcik SM, Grant WD, Ko PY (2011) Incidental findings on CT scans in the Emergency Department. Emerg Med Int 2011:1–4 Thompson RJ, Wojcik SM, Grant WD, Ko PY (2011) Incidental findings on CT scans in the Emergency Department. Emerg Med Int 2011:1–4
35.
Zurück zum Zitat Schoenfeld E, Poronsky K, Elia T, Budhram G, Garb J, Mader T (2015) Young patients with suspected uncomplicated renal colic are unlikely to have dangerous alternative diagnoses or need emergent intervention. West J Emerg Med 16(2):269–275 Schoenfeld E, Poronsky K, Elia T, Budhram G, Garb J, Mader T (2015) Young patients with suspected uncomplicated renal colic are unlikely to have dangerous alternative diagnoses or need emergent intervention. West J Emerg Med 16(2):269–275
36.
Zurück zum Zitat Schoenfeld EM, Pekow PS, Shieh MS, Scales CD, Lagu T, Lindenauer PK (2017) The Diagnosis and Management of Patients with Renal Colic across a Sample of US Hospitals: High CT Utilization Despite Low Rates of Admission and Inpatient Urologic Intervention. PLoS One 12 (1):e0169160 Schoenfeld EM, Pekow PS, Shieh MS, Scales CD, Lagu T, Lindenauer PK (2017) The Diagnosis and Management of Patients with Renal Colic across a Sample of US Hospitals: High CT Utilization Despite Low Rates of Admission and Inpatient Urologic Intervention. PLoS One 12 (1):e0169160
Metadaten
Titel
Imaging strategies for patients with suspicion of uncomplicated colic pain: diagnostic accuracy and management assessment
verfasst von
Claire Faget
Ingrid Millet
Mustapha Sebbane
Rodolphe Thuret
Cécile Verheyden
Fernanda Curros-Doyon
Nicolas Molinari
Patrice Taourel
Publikationsdatum
13.10.2020
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 5/2021
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-020-07264-z

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