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Erschienen in: Intensive Care Medicine 5/2015

01.05.2015 | Systematic Review

Impact of follow-up consultations for ICU survivors on post-ICU syndrome: a systematic review and meta-analysis

verfasst von: J. F. Jensen, T. Thomsen, D. Overgaard, M. H. Bestle, D. Christensen, I. Egerod

Erschienen in: Intensive Care Medicine | Ausgabe 5/2015

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Abstract

Purpose

To evaluate the impact of routine follow-up consultations versus standard of care for intensive care unit (ICU) survivors.

Methods

Systematic literature review from five databases (Cochrane CENTRAL, MEDLINE, EMBASE, PsycINFO, CINAHL), reference lists, citation tracking, and ongoing/unpublished trials. Randomized controlled trials investigating post-ICU consultations in adults with outcomes such as quality of life (QOL), anxiety, depression, posttraumatic stress disorder (PTSD), physical ability, cognitive function, and return to work were included. Two reviewers extracted data and assessed quality independently. The mean differences, risk ratios, and 95 % confidence intervals were calculated depending on outcome measures.

Results

From 1544 citations, five trials were included (855 patients). The overall risk of bias was low in two trials, unclear in two trials, and high in one trial. The overall quality of evidence was low. The trials assessed follow-up interventions defined as consultations informing survivors about their ICU stay. One trial found no effect on QOL. Pooling data from two trials (n = 374) showed a protective effect on risk of new onset PTSD at 3–6 months after ICU (risk ratio 0.49, 95 % CI 0.26–0.95). There was no effect on other outcomes.

Conclusions

The evidence indicates that follow-up consultations might reduce symptoms of PTSD at 3–6 months after ICU discharge in ICU survivors, but without affecting QOL and other outcomes investigated. This review highlights that planning of future RCTs should aim to standardize interventions and outcome measures to allow for comparisons across studies.
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Metadaten
Titel
Impact of follow-up consultations for ICU survivors on post-ICU syndrome: a systematic review and meta-analysis
verfasst von
J. F. Jensen
T. Thomsen
D. Overgaard
M. H. Bestle
D. Christensen
I. Egerod
Publikationsdatum
01.05.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
Intensive Care Medicine / Ausgabe 5/2015
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-015-3689-1

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