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CardioVascular and Interventional Radiology

Erschienen in:

01.12.2012 | Clinical Investigation

Incidence and Cause of Hypertension During Adrenal Radiofrequency Ablation

verfasst von: Koichiro Yamakado, Haruyuki Takaki, Tomomi Yamada, Takashi Yamanaka, Junji Uraki, Masataka Kashima, Atsuhiro Nakatsuka, Kan Takeda

Erschienen in: CardioVascular and Interventional Radiology | Ausgabe 6/2012

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Abstract

Purpose

To evaluate the incidence and cause of hypertension prospectively during adrenal radiofrequency ablation (RFA).

Methods

For this study, approved by our institutional review board, written informed consent was obtained from all patients. Patients who received RFA for adrenal tumors (adrenal ablation) and other abdominal tumors (nonadrenal ablation) were included in this prospective study. Blood pressure was monitored during RFA. Serum adrenal hormone levels including epinephrine, norepinephrine, dopamine, and cortisol levels were measured before and during RFA. The respective incidences of procedural hypertension (systolic blood pressure >200 mmHg) of the two patient groups were compared. Factors correlating with procedural systolic blood pressure were evaluated by regression analysis.

Results

Nine patients underwent adrenal RFA and another 9 patients liver (n = 5) and renal (n = 4) RFA. Asymptomatic procedural hypertension that returned to the baseline by injecting calcium blocker was found in 7 (38.9%) of 18 patients. The incidence of procedural hypertension was significantly higher in the adrenal ablation group (66.7%, 6/9) than in the nonadrenal ablation group (11.1%, 1/9, P < 0.0498). Procedural systolic blood pressure was significantly correlated with serum epinephrine (R ² = 0.68, P < 0.0001) and norepinephrine (R ² = 0.72, P < 0.0001) levels during RFA. The other adrenal hormones did not show correlation with procedural systolic blood pressure.

Conclusion

Hypertension occurs frequently during adrenal RFA because of the release of catecholamine.

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Titel: Incidence and Cause of Hypertension During Adrenal Radiofrequency Ablation
verfasst von: Koichiro Yamakado
Haruyuki Takaki
Tomomi Yamada
Takashi Yamanaka
Junji Uraki
Masataka Kashima
Atsuhiro Nakatsuka
Kan Takeda
Publikationsdatum: 01.12.2012
Verlag: Springer-Verlag
Erschienen in: CardioVascular and Interventional Radiology / Ausgabe 6/2012
Print ISSN: 0174-1551
Elektronische ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-012-0348-6

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Incidence and Cause of Hypertension During Adrenal Radiofrequency Ablation