Skip to main content
Erschienen in: Endocrine Pathology 1/2013

01.03.2013

Isolated Multiple Bilateral Thyroid Metastases from Prostatic Adenocarcinoma: Case Report and Literature Review

verfasst von: Nader M. Albsoul, Fatima N. Obeidat, Azmy M. Hadidy, Mohammad N. AlZoubi, Abtehag A. Taib, Awni D. Shahait

Erschienen in: Endocrine Pathology | Ausgabe 1/2013

Einloggen, um Zugang zu erhalten

Abstract

Solitary metastasis from prostate adenocarcinoma to thyroid gland is very rare and usually associated with other distal metastasis. This report describes for the first time isolated multiple bilateral thyroid metastasis from prostatic adenocarcinoma. A 67-year-old man who is known as a case of prostatic adenocarcinoma was admitted to a hospital as a case of a multinodular goiter on the basis of clinical and CT scan findings. Total thyroidectomy was performed and histopathology result showed adenomatous goiter containing bilateral metastatic prostatic adenocarcinoma. This is the first report of isolated multiple bilateral thyroid gland metastasis from prostatic adenocarcinoma without other distal metastasis. Such lesions are very rare and can be misdiagnosed, so high index of suspicion for thyroid metastasis should be always maintained in all oncology patients with isolated thyroid mass because early resection and thyroidectomy will change the prognosis for patient.
Literatur
2.
3.
Zurück zum Zitat Chen H, Nicol TL, Udelsman R (1999) Clinically significant, isolated metastatic disease to the thyroid gland. World J Surg 23 (2):177–180; discussion 181PubMedCrossRef Chen H, Nicol TL, Udelsman R (1999) Clinically significant, isolated metastatic disease to the thyroid gland. World J Surg 23 (2):177–180; discussion 181PubMedCrossRef
5.
Zurück zum Zitat Bubendorf L, Schopfer A, Wagner U, Sauter G, Moch H, Willi N, Gasser TC, Mihatsch MJ (2000) Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum Pathol 31 (5):578–583PubMedCrossRef Bubendorf L, Schopfer A, Wagner U, Sauter G, Moch H, Willi N, Gasser TC, Mihatsch MJ (2000) Metastatic patterns of prostate cancer: an autopsy study of 1,589 patients. Hum Pathol 31 (5):578–583PubMedCrossRef
6.
Zurück zum Zitat Ro JY, Guerrieri C, el-Naggar AK, Ordonez NG, Sorge JG, Ayala AG (1994) Carcinomas metastatic to follicular adenomas of the thyroid gland. Report of two cases. Arch Pathol Lab Med 118 (5):551–556PubMed Ro JY, Guerrieri C, el-Naggar AK, Ordonez NG, Sorge JG, Ayala AG (1994) Carcinomas metastatic to follicular adenomas of the thyroid gland. Report of two cases. Arch Pathol Lab Med 118 (5):551–556PubMed
7.
Zurück zum Zitat Michelow PM, Leiman G (1995) Metastases to the thyroid gland: diagnosis by aspiration cytology. Diagn Cytopathol 13 (3):209–213PubMedCrossRef Michelow PM, Leiman G (1995) Metastases to the thyroid gland: diagnosis by aspiration cytology. Diagn Cytopathol 13 (3):209–213PubMedCrossRef
8.
Zurück zum Zitat Momma T, Kimura S, Saito S, Onoda N (1998) [Prostate cancer with high serum level of CEA and CA19-9: a case report]. Hinyokika Kiyo 44 (3):187–191PubMed Momma T, Kimura S, Saito S, Onoda N (1998) [Prostate cancer with high serum level of CEA and CA19-9: a case report]. Hinyokika Kiyo 44 (3):187–191PubMed
9.
Zurück zum Zitat Bayram F, Soyuer I, Atmaca H, Demirci D, Gokce C, Canoz O, Unluhizarci K, Kelestimur F (2004) Prostatic adenocarcinoma metastasis in the thyroid gland. Endocr J 51 (4):445–448. PubMedCrossRef Bayram F, Soyuer I, Atmaca H, Demirci D, Gokce C, Canoz O, Unluhizarci K, Kelestimur F (2004) Prostatic adenocarcinoma metastasis in the thyroid gland. Endocr J 51 (4):445–448. PubMedCrossRef
10.
Zurück zum Zitat Selimoglu H, Duran C, Saraydaroglu O, Guclu M, Kiyici S, Ersoy C, Eren MA, Tuncel E, Imamoglu S (2007) Prostate cancer metastasis to thyroid gland. Tumori 93 (3):292–295PubMed Selimoglu H, Duran C, Saraydaroglu O, Guclu M, Kiyici S, Ersoy C, Eren MA, Tuncel E, Imamoglu S (2007) Prostate cancer metastasis to thyroid gland. Tumori 93 (3):292–295PubMed
12.
Zurück zum Zitat Nakhjavani M, Gharib H, Goellner JR, Heerden JA (1999) Direct extension of malignant lesions to the thyroid gland from adjacent organs: report of 17 cases. Endocr Pract 5 (2):69–71. PubMed Nakhjavani M, Gharib H, Goellner JR, Heerden JA (1999) Direct extension of malignant lesions to the thyroid gland from adjacent organs: report of 17 cases. Endocr Pract 5 (2):69–71. PubMed
13.
Zurück zum Zitat Shimaoka K, Sokal JE, Pickren JW (1962) Metastatic neoplasms in the thyroid gland. Pathological and clinical findings. Cancer 15:557–565PubMedCrossRef Shimaoka K, Sokal JE, Pickren JW (1962) Metastatic neoplasms in the thyroid gland. Pathological and clinical findings. Cancer 15:557–565PubMedCrossRef
14.
Zurück zum Zitat Zirkin HJ, Tovi F (1984) Tracheal carcinoma presenting as a thyroid tumor. J Surg Oncol 26 (4):268–271PubMedCrossRef Zirkin HJ, Tovi F (1984) Tracheal carcinoma presenting as a thyroid tumor. J Surg Oncol 26 (4):268–271PubMedCrossRef
16.
Zurück zum Zitat Stevens TM, Richards AT, Bewtra C, Sharma P (2011) Tumors metastatic to thyroid neoplasms: a case report and review of the literature. Patholog Res Int 2011:238693. doi:10.4061/2011/238693 PubMed Stevens TM, Richards AT, Bewtra C, Sharma P (2011) Tumors metastatic to thyroid neoplasms: a case report and review of the literature. Patholog Res Int 2011:238693. doi:10.​4061/​2011/​238693 PubMed
17.
Zurück zum Zitat Escudero RM, Amo FH, Martinez MC, Jimenez JT, Alonso AH, Pinies GO, Fernandez CH (2011) Metastatic prostate cancer on the thyroid cartilage: unusual symptoms of prostatic adenocarcinoma. Case report. Arch Esp Urol 64 (2):132–135PubMed Escudero RM, Amo FH, Martinez MC, Jimenez JT, Alonso AH, Pinies GO, Fernandez CH (2011) Metastatic prostate cancer on the thyroid cartilage: unusual symptoms of prostatic adenocarcinoma. Case report. Arch Esp Urol 64 (2):132–135PubMed
18.
Zurück zum Zitat Kabeer MA, Lloyd-Davies E, Maskell G, Hohle R, Mathew J (2007) Metastatic prostate cancer masquerading clinically and radiologically as a primary caecal carcinoma. World J Surg Oncol 5:2. doi:10.1186/1477-7819-5-2 PubMedCrossRef Kabeer MA, Lloyd-Davies E, Maskell G, Hohle R, Mathew J (2007) Metastatic prostate cancer masquerading clinically and radiologically as a primary caecal carcinoma. World J Surg Oncol 5:2. doi:10.​1186/​1477-7819-5-2 PubMedCrossRef
19.
Zurück zum Zitat Gerges AS, Shehata SR, Gouda IA (2006) Metastasis to the thyroid gland; unusual site of metastasis. J Egypt Natl Canc Inst 18 (1):67–72PubMed Gerges AS, Shehata SR, Gouda IA (2006) Metastasis to the thyroid gland; unusual site of metastasis. J Egypt Natl Canc Inst 18 (1):67–72PubMed
20.
Zurück zum Zitat McCabe DP, Farrar WB, Petkov TM, Finkelmeier W, O'Dwyer P, James A (1985) Clinical and pathologic correlations in disease metastatic to the thyroid gland. Am J Surg 150 (4):519–523. PubMedCrossRef McCabe DP, Farrar WB, Petkov TM, Finkelmeier W, O'Dwyer P, James A (1985) Clinical and pathologic correlations in disease metastatic to the thyroid gland. Am J Surg 150 (4):519–523. PubMedCrossRef
21.
Zurück zum Zitat A R Gamble JAB, J E Ronan, D Pearson, and I O Ellis (1993) Use of tumour marker immuno-reactivity to identify primary site of metastatic cancer. BMJ 306:295–298CrossRef A R Gamble JAB, J E Ronan, D Pearson, and I O Ellis (1993) Use of tumour marker immuno-reactivity to identify primary site of metastatic cancer. BMJ 306:295–298CrossRef
22.
Zurück zum Zitat Papi G, Fadda G, Corsello SM, Corrado S, Rossi ED, Radighieri E, Miraglia A, Carani C, Pontecorvi A (2007) Metastases to the thyroid gland: prevalence, clinicopathological aspects and prognosis: a 10-year experience. Clin Endocrinol (Oxf) 66 (4):565–571. doi:10.1111/j.1365-2265.2007.02773.x Papi G, Fadda G, Corsello SM, Corrado S, Rossi ED, Radighieri E, Miraglia A, Carani C, Pontecorvi A (2007) Metastases to the thyroid gland: prevalence, clinicopathological aspects and prognosis: a 10-year experience. Clin Endocrinol (Oxf) 66 (4):565–571. doi:10.​1111/​j.​1365-2265.​2007.​02773.​x
Metadaten
Titel
Isolated Multiple Bilateral Thyroid Metastases from Prostatic Adenocarcinoma: Case Report and Literature Review
verfasst von
Nader M. Albsoul
Fatima N. Obeidat
Azmy M. Hadidy
Mohammad N. AlZoubi
Abtehag A. Taib
Awni D. Shahait
Publikationsdatum
01.03.2013
Verlag
Springer US
Erschienen in
Endocrine Pathology / Ausgabe 1/2013
Print ISSN: 1046-3976
Elektronische ISSN: 1559-0097
DOI
https://doi.org/10.1007/s12022-013-9232-4

Weitere Artikel der Ausgabe 1/2013

Endocrine Pathology 1/2013 Zur Ausgabe

Neu im Fachgebiet Pathologie

Molekularpathologische Untersuchungen im Wandel der Zeit

Open Access Biomarker Leitthema

Um auch an kleinen Gewebeproben zuverlässige und reproduzierbare Ergebnisse zu gewährleisten ist eine strenge Qualitätskontrolle in jedem Schritt des Arbeitsablaufs erforderlich. Eine nicht ordnungsgemäße Prüfung oder Behandlung des …

Vergleichende Pathologie in der onkologischen Forschung

Pathologie Leitthema

Die vergleichende experimentelle Pathologie („comparative experimental pathology“) ist ein Fachbereich an der Schnittstelle von Human- und Veterinärmedizin. Sie widmet sich der vergleichenden Erforschung von Gemeinsamkeiten und Unterschieden von …

Gastrointestinale Stromatumoren

Open Access GIST CME-Artikel

Gastrointestinale Stromatumoren (GIST) stellen seit über 20 Jahren ein Paradigma für die zielgerichtete Therapie mit Tyrosinkinaseinhibitoren dar. Eine elementare Voraussetzung für eine mögliche neoadjuvante oder adjuvante Behandlung bei …

Personalisierte Medizin in der Onkologie

Aufgrund des erheblichen technologischen Fortschritts in der molekularen und genetischen Diagnostik sowie zunehmender Erkenntnisse über die molekulare Pathogenese von Krankheiten hat in den letzten zwei Jahrzehnten ein grundlegender …