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Erschienen in:
01.04.2014 | Images That Teach
Left atrial metastasis of Hürthle-cell thyroid carcinoma mimicking myxoma
Erschienen in: Journal of Nuclear Cardiology | Ausgabe 2/2014
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A 52-year-old male patient affected by a Hürthle-cell thyroid carcinoma treated with thyroidectomy and radiometabolic therapy with Iodine-131 (I-131) underwent fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-18-FDG PET/CT) for restaging due to increased serum thyroglobulin levels (10 ng·mL−1) and negative I-131 whole-body scan (Figure 1A, B).
Figure 1
Iodine-131 whole-body scans in anterior (A) and posterior view (B) showing no areas of abnormal tracer uptake in a patient affected by Hürthle-cell thyroid carcinoma treated with thyroidectomy and subsequent radiometabolic therapy. Axial F-18-FDG PET image (C) showing an area of increased radiopharmaceutical uptake (SUVmax: 8) corresponding to a 2.5-cm lesion located in the left atrium at MRI (D), as demonstrated by fused PET/MRI image (E). Hematoxylin and eosin stain (F) demonstrated a neoplastic lesion surrounded by a cap of fibrin (asterisk) and constituted by eosinophilic cells with granular cytoplasm mixed up with lymphocytes (arrows). The immunohistochemical stain with thyroid transcription factor-1 antibody showed intense nuclear expression (G) consistent with metastatic Hürthle-cell thyroid carcinoma
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