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Erschienen in: Heart Failure Reviews 6/2010

01.11.2010

Left ventricular non-compaction and its cardiac and neurologic implications

verfasst von: Josef Finsterer

Erschienen in: Heart Failure Reviews | Ausgabe 6/2010

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Abstract

Left ventricular non-compaction, also known as left ventricular hypertrabeculation (LVHT), is a morphological abnormality of the left ventricular myocardium, characterised by a meshwork of myocardial strings, interlacing, and orderless in arrangement. LVHT is most frequently located in the apex and the lateral wall and may occur with or without other congenital or acquired cardiac abnormalities. LVHT is believed to be congenital in the majority of the cases but may develop during life in single cases (acquired LVHT). Congenital LVHT is believed to result from defective late-stage embryonic development of the myocardial architecture. The pathogenesis of acquired LVHT remains speculative. LVHT is most frequently found on transthoracic echocardiography and cardiac MRI but may be visualised also with other imaging techniques. In the majority of the cases, LVHT is associated with hereditary cardiac, neuromuscular, non-cardiac/non-muscle disease, or chromosomal aberrations. In the majority of the cases, LVHT is complicated by ventricular arrhythmias, systolic dysfunction, cardiac embolism, or sudden cardiac death. LVHT per se does not require a specific treatment. Only in case of complications, such as ventricular arrhythmias, cardioembolism, or systolic dysfunction, adequate therapy is indicated. Though initially assessed as poor, the prognosis of LVHT has meanwhile improved, most likely due to the increased awareness for the abnormality and the timely administration of adequate therapy.
Literatur
1.
Zurück zum Zitat Engberding R, Yelbuz TM, Breithardt G (2007) Isolated noncompaction of the left ventricular myocardium—a review of the literature two decades after the initial case description. Clin Res Cardiol 96:481–488PubMedCrossRef Engberding R, Yelbuz TM, Breithardt G (2007) Isolated noncompaction of the left ventricular myocardium—a review of the literature two decades after the initial case description. Clin Res Cardiol 96:481–488PubMedCrossRef
2.
Zurück zum Zitat Finsterer J (2009) Cardiogenetics, neurogenetics, and pathogenetics of left ventricular hypertrabeculation/noncompaction. Pediatr Cardiol 30:659–681PubMedCrossRef Finsterer J (2009) Cardiogenetics, neurogenetics, and pathogenetics of left ventricular hypertrabeculation/noncompaction. Pediatr Cardiol 30:659–681PubMedCrossRef
3.
Zurück zum Zitat Breckenridge RA, Anderson RH, Elliott PM (2007) Isolated left ventricular non-compaction: the case for abnormal myocardial development. Cardiol Young 17:124–129PubMedCrossRef Breckenridge RA, Anderson RH, Elliott PM (2007) Isolated left ventricular non-compaction: the case for abnormal myocardial development. Cardiol Young 17:124–129PubMedCrossRef
4.
Zurück zum Zitat Dusek J, Ostádal B, Duskova M (1975) Postnatal persistence of spongy myocardium with embryonic blood supply. Arch Pathol 99:312–317PubMed Dusek J, Ostádal B, Duskova M (1975) Postnatal persistence of spongy myocardium with embryonic blood supply. Arch Pathol 99:312–317PubMed
5.
Zurück zum Zitat Engberding R, Bender F (1984) Identification of a rare congenital anomaly of the myocardium by two-dimensional echocardiography: persistence of isolated myocardial sinusoids. Am J Cardiol 53:1733–1734PubMedCrossRef Engberding R, Bender F (1984) Identification of a rare congenital anomaly of the myocardium by two-dimensional echocardiography: persistence of isolated myocardial sinusoids. Am J Cardiol 53:1733–1734PubMedCrossRef
6.
Zurück zum Zitat Finsterer J, Stöllberger C, Wegmann R, Jarius C, Janssen B (2001) Left ventricular hypertrabeculation in myotonic dystrophy type 1. Herz 26:287–290PubMedCrossRef Finsterer J, Stöllberger C, Wegmann R, Jarius C, Janssen B (2001) Left ventricular hypertrabeculation in myotonic dystrophy type 1. Herz 26:287–290PubMedCrossRef
7.
Zurück zum Zitat Bellet S, Gouley BA (1932) Congenital heart disease with multiple cardiac anomalies: report of a case showing aortic atresia, fibrous scar in myocardium and embryonal sinusoidal remains. Am J Med Sci 183:458–465CrossRef Bellet S, Gouley BA (1932) Congenital heart disease with multiple cardiac anomalies: report of a case showing aortic atresia, fibrous scar in myocardium and embryonal sinusoidal remains. Am J Med Sci 183:458–465CrossRef
8.
Zurück zum Zitat Anderson RH (2008) Ventricular non-compaction—a frequently ignored finding? Eur Heart J 29:10–11PubMedCrossRef Anderson RH (2008) Ventricular non-compaction—a frequently ignored finding? Eur Heart J 29:10–11PubMedCrossRef
9.
Zurück zum Zitat Pfammatter JP, Paul T, Flik J, Drescher J, Kallfelz HC (1995) Q-fever associated myocarditis in a 14-year-old boy. Z Kardiol 84:947–950PubMed Pfammatter JP, Paul T, Flik J, Drescher J, Kallfelz HC (1995) Q-fever associated myocarditis in a 14-year-old boy. Z Kardiol 84:947–950PubMed
10.
Zurück zum Zitat Stöllberger C, Finsterer J, Blazek G, Bittner RE (1996) Left ventricular non-compaction in a patient with Becker’s muscular dystrophy. Heart 76:380PubMedCrossRef Stöllberger C, Finsterer J, Blazek G, Bittner RE (1996) Left ventricular non-compaction in a patient with Becker’s muscular dystrophy. Heart 76:380PubMedCrossRef
11.
Zurück zum Zitat Ritter M, Oechslin E, Sütsch G, Attenhofer C, Schneider J, Jenni R (1997) Isolated noncompaction of the myocardium in adults. Mayo Clin Proc 72:26–31PubMedCrossRef Ritter M, Oechslin E, Sütsch G, Attenhofer C, Schneider J, Jenni R (1997) Isolated noncompaction of the myocardium in adults. Mayo Clin Proc 72:26–31PubMedCrossRef
12.
Zurück zum Zitat Chin TK, Perloff JK, Williams RG, Jue K, Mohrmann R (1990) Isolated noncompaction of left ventricular myocardium. A study of eight cases. Circulation 82:507–513PubMed Chin TK, Perloff JK, Williams RG, Jue K, Mohrmann R (1990) Isolated noncompaction of left ventricular myocardium. A study of eight cases. Circulation 82:507–513PubMed
13.
Zurück zum Zitat Tavli V, Kayhan B, Okur FF, Kozan M, Kirman M, Bakiler AR, Tekdoğan M (2001) Noncompaction of the right ventricle following Senning repair. Turk J Pediatr 43:261–263PubMed Tavli V, Kayhan B, Okur FF, Kozan M, Kirman M, Bakiler AR, Tekdoğan M (2001) Noncompaction of the right ventricle following Senning repair. Turk J Pediatr 43:261–263PubMed
14.
Zurück zum Zitat Oechslin EN, Attenhofer Jost CH, Rojas JR, Kaufmann PA, Jenni R (2000) Long-term follow-up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis. J Am Coll Cardiol 36:493–500PubMedCrossRef Oechslin EN, Attenhofer Jost CH, Rojas JR, Kaufmann PA, Jenni R (2000) Long-term follow-up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis. J Am Coll Cardiol 36:493–500PubMedCrossRef
15.
Zurück zum Zitat Stöllberger C, Blazek G, Winkler-Dworak M, Finsterer J (2008) Sex differences in left ventricular noncompaction in patients with and without neuromuscular disorders. Rev Esp Cardiol 61:130–136PubMed Stöllberger C, Blazek G, Winkler-Dworak M, Finsterer J (2008) Sex differences in left ventricular noncompaction in patients with and without neuromuscular disorders. Rev Esp Cardiol 61:130–136PubMed
16.
Zurück zum Zitat Pignatelli RH, McMahon CJ, Dreyer WJ, Denfield SW, Price J, Belmont JW, Craigen WJ, Wu J, El Said H, Bezold LI, Clunie S, Fernbach S, Bowles NE, Towbin JA (2003) Clinical characterization of left ventricular noncompaction in children: a relatively common form of cardiomyopathy. Circulation 108:2672–2678PubMedCrossRef Pignatelli RH, McMahon CJ, Dreyer WJ, Denfield SW, Price J, Belmont JW, Craigen WJ, Wu J, El Said H, Bezold LI, Clunie S, Fernbach S, Bowles NE, Towbin JA (2003) Clinical characterization of left ventricular noncompaction in children: a relatively common form of cardiomyopathy. Circulation 108:2672–2678PubMedCrossRef
17.
Zurück zum Zitat Ali SK, Godman MJ (2004) The variable clinical presentation of, and outcome for, noncompaction of the ventricular myocardium in infants and children, an under-diagnosed cardiomyopathy. Cardiol Young 14:409–416PubMedCrossRef Ali SK, Godman MJ (2004) The variable clinical presentation of, and outcome for, noncompaction of the ventricular myocardium in infants and children, an under-diagnosed cardiomyopathy. Cardiol Young 14:409–416PubMedCrossRef
18.
Zurück zum Zitat Stöllberger C, Finsterer J (2004) Left ventricular hypertrabeculation/noncompaction. J Am Soc Echocardiogr 17:91–100PubMedCrossRef Stöllberger C, Finsterer J (2004) Left ventricular hypertrabeculation/noncompaction. J Am Soc Echocardiogr 17:91–100PubMedCrossRef
19.
Zurück zum Zitat He T, Zeng HS, Le WB, Li XH, Lu ZY (2007) Clinical characterization and outcome of patients with noncompaction of ventricular myocardium]. Zhonghua Xin Xue Guan Bing Za Zhi 35:548–551PubMed He T, Zeng HS, Le WB, Li XH, Lu ZY (2007) Clinical characterization and outcome of patients with noncompaction of ventricular myocardium]. Zhonghua Xin Xue Guan Bing Za Zhi 35:548–551PubMed
20.
Zurück zum Zitat Kohli SK, Pantazis AA, Shah JS, Adeyemi B, Jackson G, McKenna WJ, Sharma S, Elliott PM (2008) Diagnosis of left-ventricular non-compaction in patients with left-ventricular systolic dysfunction: time for a reappraisal of diagnostic criteria? Eur Heart J 29:89–95PubMedCrossRef Kohli SK, Pantazis AA, Shah JS, Adeyemi B, Jackson G, McKenna WJ, Sharma S, Elliott PM (2008) Diagnosis of left-ventricular non-compaction in patients with left-ventricular systolic dysfunction: time for a reappraisal of diagnostic criteria? Eur Heart J 29:89–95PubMedCrossRef
21.
Zurück zum Zitat Nugent AW, Daubeney PE, Chondros P, Carlin JB, Cheung M, Wilkinson LC, Davis AM, Kahler SG, Chow CW, Wilkinson JL, Weintraub RG (2003) National Australian childhood cardiomyopathy study. The epidemiology of childhood cardiomyopathy in Australia. N Engl J Med 348:1639–1646PubMedCrossRef Nugent AW, Daubeney PE, Chondros P, Carlin JB, Cheung M, Wilkinson LC, Davis AM, Kahler SG, Chow CW, Wilkinson JL, Weintraub RG (2003) National Australian childhood cardiomyopathy study. The epidemiology of childhood cardiomyopathy in Australia. N Engl J Med 348:1639–1646PubMedCrossRef
22.
Zurück zum Zitat Boyd MT, Seward JB, Tajik AJ, Edwards WD (1987) Frequency and location of prominent left ventricular trabeculations at autopsy in 474 normal human hearts: implications for evaluation of mural thrombi by two-dimensional echocardiography. J Am Coll Cardiol 9:323–326PubMedCrossRef Boyd MT, Seward JB, Tajik AJ, Edwards WD (1987) Frequency and location of prominent left ventricular trabeculations at autopsy in 474 normal human hearts: implications for evaluation of mural thrombi by two-dimensional echocardiography. J Am Coll Cardiol 9:323–326PubMedCrossRef
23.
Zurück zum Zitat Fernández-Golfín C, Pachón M, Corros C, Bustos A, Cabeza B, Ferreirós J, de Isla LP, Macaya C, Zamorano J (2009) Left ventricular trabeculae: quantification in different cardiac diseases and impact on left ventricular morphological and functional parameters assessed with cardiac magnetic resonance. J Cardiovasc Med (Hagerstown) 10:827–833CrossRef Fernández-Golfín C, Pachón M, Corros C, Bustos A, Cabeza B, Ferreirós J, de Isla LP, Macaya C, Zamorano J (2009) Left ventricular trabeculae: quantification in different cardiac diseases and impact on left ventricular morphological and functional parameters assessed with cardiac magnetic resonance. J Cardiovasc Med (Hagerstown) 10:827–833CrossRef
24.
Zurück zum Zitat Cruden NL, Denvir MA (2008) Isolated left ventricular non-compaction as an unusual cause of heart failure: a case report. J Med Case Rep 2:269CrossRef Cruden NL, Denvir MA (2008) Isolated left ventricular non-compaction as an unusual cause of heart failure: a case report. J Med Case Rep 2:269CrossRef
25.
Zurück zum Zitat Saeed S, Vegsundvåg J, Lode I (2009) Noncompaction of the left ventricular myocardium. Tidsskr Nor Laegeforen 129:1104–1107PubMedCrossRef Saeed S, Vegsundvåg J, Lode I (2009) Noncompaction of the left ventricular myocardium. Tidsskr Nor Laegeforen 129:1104–1107PubMedCrossRef
26.
Zurück zum Zitat Zimpfer A, Miny P, Dombrowski U, Tolnay M, Meyer P, Bruder E (2007) Upper limb amelia, facial clefts, holoprosencephaly, and interrupted aortic arch. Fetal Pediatr Pathol 26:169–176PubMedCrossRef Zimpfer A, Miny P, Dombrowski U, Tolnay M, Meyer P, Bruder E (2007) Upper limb amelia, facial clefts, holoprosencephaly, and interrupted aortic arch. Fetal Pediatr Pathol 26:169–176PubMedCrossRef
27.
Zurück zum Zitat Panduranga P, Mukhaini MK (2009) Left-ventricular non-compaction with coronary artery disease. Int J Cardiol (in press) Panduranga P, Mukhaini MK (2009) Left-ventricular non-compaction with coronary artery disease. Int J Cardiol (in press)
28.
Zurück zum Zitat Monserrat L, Barriales-Villa R, Hermida-Prieto M (2008) Apical hypertrophic cardiomyopathy and left ventricular non-compaction: two faces of the same disease. Heart 94:1253PubMedCrossRef Monserrat L, Barriales-Villa R, Hermida-Prieto M (2008) Apical hypertrophic cardiomyopathy and left ventricular non-compaction: two faces of the same disease. Heart 94:1253PubMedCrossRef
29.
Zurück zum Zitat Burke A, Mont E, Kutys R, Virmani R (2005) Left ventricular noncompaction: a pathological study of 14 cases. Hum Pathol 36:403–411PubMedCrossRef Burke A, Mont E, Kutys R, Virmani R (2005) Left ventricular noncompaction: a pathological study of 14 cases. Hum Pathol 36:403–411PubMedCrossRef
30.
Zurück zum Zitat Buss SJ, Mereles D, Katus HA, Hardt SE (2009) Left ventricular non-compaction cardiomyopathy mimicking an infiltrative cardiac disease. Int J Cardiol (in press) Buss SJ, Mereles D, Katus HA, Hardt SE (2009) Left ventricular non-compaction cardiomyopathy mimicking an infiltrative cardiac disease. Int J Cardiol (in press)
31.
Zurück zum Zitat Fazio G, Novo G, Casalicchio C, Di Gesaro G, Sutera L, Grassedonio E, Cracolici E, Pitruzzella V, Incalcaterra E, Pipitone S, Midiri M, Novo S (2009) Left ventricular non-compaction cardiomyopathy in children: is segmental fibrosis the cause of tissue Doppler alterations and of EF reduction? Int J Cardiol 132:278–280PubMedCrossRef Fazio G, Novo G, Casalicchio C, Di Gesaro G, Sutera L, Grassedonio E, Cracolici E, Pitruzzella V, Incalcaterra E, Pipitone S, Midiri M, Novo S (2009) Left ventricular non-compaction cardiomyopathy in children: is segmental fibrosis the cause of tissue Doppler alterations and of EF reduction? Int J Cardiol 132:278–280PubMedCrossRef
32.
Zurück zum Zitat Bladt O, Vanhoenacker R, Bevernage C, Leyman P (2008) Isolated noncompaction of ventricular myocardium. Diagnosis with multidetector computed tomography. JBR-BTR 91:153–154PubMed Bladt O, Vanhoenacker R, Bevernage C, Leyman P (2008) Isolated noncompaction of ventricular myocardium. Diagnosis with multidetector computed tomography. JBR-BTR 91:153–154PubMed
33.
Zurück zum Zitat Nemes A, Caliskan K, Geleijnse ML, Soliman OI, Vletter WB, ten Cate FJ (2009) Reduced regional systolic function is not confined to the noncompacted segments in noncompaction cardiomyopathy. Int J Cardiol 134:366–370PubMedCrossRef Nemes A, Caliskan K, Geleijnse ML, Soliman OI, Vletter WB, ten Cate FJ (2009) Reduced regional systolic function is not confined to the noncompacted segments in noncompaction cardiomyopathy. Int J Cardiol 134:366–370PubMedCrossRef
34.
Zurück zum Zitat van Dalen BM, Caliskan K, Soliman OI, Nemes A, Vletter WB, Ten Cate FJ, Geleijnse ML (2008) Left ventricular solid body rotation in non-compaction cardiomyopathy: a potential new objective and quantitative functional diagnostic criterion? Eur J Heart Fail 10:1088–1093PubMedCrossRef van Dalen BM, Caliskan K, Soliman OI, Nemes A, Vletter WB, Ten Cate FJ, Geleijnse ML (2008) Left ventricular solid body rotation in non-compaction cardiomyopathy: a potential new objective and quantitative functional diagnostic criterion? Eur J Heart Fail 10:1088–1093PubMedCrossRef
35.
Zurück zum Zitat Ichida F, Hamamichi Y, Miyawaki T, Ono Y, Kamiya T, Akagi T, Hamada H, Hirose O, Isobe T, Yamada K, Kurotobi S, Mito H, Miyake T, Murakami Y, Nishi T, Shinohara M, Seguchi M, Tashiro S, Tomimatsu H (1999) Clinical features of isolated noncompaction of the ventricular myocardium: long-term clinical course, hemodynamic properties, and genetic background. J Am Coll Cardiol 34:233–240PubMedCrossRef Ichida F, Hamamichi Y, Miyawaki T, Ono Y, Kamiya T, Akagi T, Hamada H, Hirose O, Isobe T, Yamada K, Kurotobi S, Mito H, Miyake T, Murakami Y, Nishi T, Shinohara M, Seguchi M, Tashiro S, Tomimatsu H (1999) Clinical features of isolated noncompaction of the ventricular myocardium: long-term clinical course, hemodynamic properties, and genetic background. J Am Coll Cardiol 34:233–240PubMedCrossRef
36.
Zurück zum Zitat Belanger AR, Miller MA, Donthireddi UR, Najovits AJ, Goldman ME (2008) New classification scheme of left ventricular noncompaction and correlation with ventricular performance. Am J Cardiol 102:92–96PubMedCrossRef Belanger AR, Miller MA, Donthireddi UR, Najovits AJ, Goldman ME (2008) New classification scheme of left ventricular noncompaction and correlation with ventricular performance. Am J Cardiol 102:92–96PubMedCrossRef
37.
Zurück zum Zitat Stanton C, Bruce C, Connolly H, Brady P, Syed I, Hodge D, Asirvatham S, Friedman P (2009) Isolated left ventricular noncompaction syndrome. Am J Cardiol 104:1135–1138PubMedCrossRef Stanton C, Bruce C, Connolly H, Brady P, Syed I, Hodge D, Asirvatham S, Friedman P (2009) Isolated left ventricular noncompaction syndrome. Am J Cardiol 104:1135–1138PubMedCrossRef
38.
Zurück zum Zitat Petersen SE, Selvanayagam JB, Wiesmann F, Robson MD, Francis JM, Anderson RH, Watkins H, Neubauer S (2005) Left ventricular non-compaction: insights from cardiovascular magnetic resonance imaging. J Am Coll Cardiol 46:101–105PubMedCrossRef Petersen SE, Selvanayagam JB, Wiesmann F, Robson MD, Francis JM, Anderson RH, Watkins H, Neubauer S (2005) Left ventricular non-compaction: insights from cardiovascular magnetic resonance imaging. J Am Coll Cardiol 46:101–105PubMedCrossRef
39.
Zurück zum Zitat Junqueira FP, Fernandes FD, Coutinho AC, De Pontes PV, Domingues RC (2009) Case report. Isolated left ventricular myocardium non-compaction: MR imaging findings from three cases. Br J Radiol 82:e37–e41PubMedCrossRef Junqueira FP, Fernandes FD, Coutinho AC, De Pontes PV, Domingues RC (2009) Case report. Isolated left ventricular myocardium non-compaction: MR imaging findings from three cases. Br J Radiol 82:e37–e41PubMedCrossRef
40.
Zurück zum Zitat Martín M, Santamarta E, Saiz A, Morís C (2009) Late gadolinium enhancement in non-compaction cardiomyopathy. Rev Esp Cardiol 62:822–823PubMedCrossRef Martín M, Santamarta E, Saiz A, Morís C (2009) Late gadolinium enhancement in non-compaction cardiomyopathy. Rev Esp Cardiol 62:822–823PubMedCrossRef
41.
Zurück zum Zitat Kurita T, Onishi K, Ogawa T, Kasai A, Sakuma H, Ito M (2008) A case of clover-shaped left ventricular non-compaction. Eur Heart J 29:569PubMedCrossRef Kurita T, Onishi K, Ogawa T, Kasai A, Sakuma H, Ito M (2008) A case of clover-shaped left ventricular non-compaction. Eur Heart J 29:569PubMedCrossRef
42.
Zurück zum Zitat Calvillo P, Martí-Bonmatí L, Chaustre F, Roldán I, Mora V, Peláez A, Cogollos J, Ballestín J (2009) MRI quantification of myocardial function, perfusion, and enhancement in patients with left-ventricular noncompaction. Radiologia 51:45–56PubMedCrossRef Calvillo P, Martí-Bonmatí L, Chaustre F, Roldán I, Mora V, Peláez A, Cogollos J, Ballestín J (2009) MRI quantification of myocardial function, perfusion, and enhancement in patients with left-ventricular noncompaction. Radiologia 51:45–56PubMedCrossRef
43.
Zurück zum Zitat Ivan D, Flamm SD, Abrams J, Kindo M, Heck K, Frazier OH (2005) Isolated ventricular non-compaction in adults with idiopathic cardiomyopathy: cardiac magnetic resonance and pathologic characterization of the anomaly. J Heart Lung Transplant 24:781–786PubMedCrossRef Ivan D, Flamm SD, Abrams J, Kindo M, Heck K, Frazier OH (2005) Isolated ventricular non-compaction in adults with idiopathic cardiomyopathy: cardiac magnetic resonance and pathologic characterization of the anomaly. J Heart Lung Transplant 24:781–786PubMedCrossRef
44.
Zurück zum Zitat Amir O, Delgado RM 3rd, Kar B, Smart FW (2009) The value of cardiac magnetic resonance imaging in the diagnosis of isolated non-compaction of the left ventricle. Isr Med Assoc J 11:313–314PubMed Amir O, Delgado RM 3rd, Kar B, Smart FW (2009) The value of cardiac magnetic resonance imaging in the diagnosis of isolated non-compaction of the left ventricle. Isr Med Assoc J 11:313–314PubMed
45.
Zurück zum Zitat Shang JF, Chen D, Zhang HX, Fang W, Wu Y, Xiao L, Lian GL (2009) Clinicopathologic analyses of non-compaction of ventricular myocardium. Zhonghua Bing Li Xue Za Zhi 38:333–336PubMed Shang JF, Chen D, Zhang HX, Fang W, Wu Y, Xiao L, Lian GL (2009) Clinicopathologic analyses of non-compaction of ventricular myocardium. Zhonghua Bing Li Xue Za Zhi 38:333–336PubMed
46.
Zurück zum Zitat Captur G, Nihoyannopoulos P (2009) Left ventricular non-compaction: genetic heterogeneity, diagnosis and clinical course. Int J Cardiol (in press) Captur G, Nihoyannopoulos P (2009) Left ventricular non-compaction: genetic heterogeneity, diagnosis and clinical course. Int J Cardiol (in press)
47.
Zurück zum Zitat Barbosa ND, Azeka E, Aiello VD, Viana F, Jatene M, Tanamati C, Marcial MB (2008) Isolated left ventricular noncompaction: unusual cause of decompensated heart failure and indication of heart transplantation in the early infancy—case report and literature review. Clinics (Sao Paulo) 63:136–139 Barbosa ND, Azeka E, Aiello VD, Viana F, Jatene M, Tanamati C, Marcial MB (2008) Isolated left ventricular noncompaction: unusual cause of decompensated heart failure and indication of heart transplantation in the early infancy—case report and literature review. Clinics (Sao Paulo) 63:136–139
48.
Zurück zum Zitat Ozkutlu S, Bostan O, Karagöz T, Deren O, Tekinalp G (2007) Prenatal diagnosis of isolated non-compaction of the ventricular myocardium: study of six cases. Pediatr Int 49:172–176PubMedCrossRef Ozkutlu S, Bostan O, Karagöz T, Deren O, Tekinalp G (2007) Prenatal diagnosis of isolated non-compaction of the ventricular myocardium: study of six cases. Pediatr Int 49:172–176PubMedCrossRef
49.
Zurück zum Zitat Stöllberger C, Preiser J, Finsterer J (2004) Histological detection of intramyocardial abscesses in Candida sepsis mimicking left ventricular non-compaction/hyertrabeculation on echocardiography. Mycoses 47:72–75PubMedCrossRef Stöllberger C, Preiser J, Finsterer J (2004) Histological detection of intramyocardial abscesses in Candida sepsis mimicking left ventricular non-compaction/hyertrabeculation on echocardiography. Mycoses 47:72–75PubMedCrossRef
50.
Zurück zum Zitat Wlodarska EK, Wozniak O, Konka M, Piotrowska-Kownacka D, Walczak E, Hoffman P (2009) Isolated ventricular noncompaction mimicking arrhythmogenic right ventricular cardiomyopathy—a study of nine patients. Int J Cardiol (in press) Wlodarska EK, Wozniak O, Konka M, Piotrowska-Kownacka D, Walczak E, Hoffman P (2009) Isolated ventricular noncompaction mimicking arrhythmogenic right ventricular cardiomyopathy—a study of nine patients. Int J Cardiol (in press)
51.
Zurück zum Zitat Kelley-Hedgepeth A, Towbin JA, Maron MS (2009) Images in cardiovascular medicine. Overlapping phenotypes: left ventricular noncompaction and hypertrophic cardiomyopathy. Circulation 119 Kelley-Hedgepeth A, Towbin JA, Maron MS (2009) Images in cardiovascular medicine. Overlapping phenotypes: left ventricular noncompaction and hypertrophic cardiomyopathy. Circulation 119
52.
Zurück zum Zitat Suvarna JC, Deshmukh CT, Hajela SA (2009) Left ventricular noncompaction: a cardiomyopathy often mistaken. Indian J Med Sci 63:303–307PubMedCrossRef Suvarna JC, Deshmukh CT, Hajela SA (2009) Left ventricular noncompaction: a cardiomyopathy often mistaken. Indian J Med Sci 63:303–307PubMedCrossRef
53.
Zurück zum Zitat El-Menyar AA, Gendi SM, Numan MT (2007) Noncompaction cardiomyopathy in the state of Qatar. Saudi Med J 28:429–434PubMed El-Menyar AA, Gendi SM, Numan MT (2007) Noncompaction cardiomyopathy in the state of Qatar. Saudi Med J 28:429–434PubMed
54.
Zurück zum Zitat Gimeno JR, Lacunza J, García-Alberola A, Cerdán MC, Oliva MJ, García-Molina E, López-Ruiz M, Castro F, González-Carrillo J, de la Morena G, Valdés M (2009) Penetrance and risk profile in inherited cardiac diseases studied in a dedicated screening clinic. Am J Cardiol 104:406–410PubMedCrossRef Gimeno JR, Lacunza J, García-Alberola A, Cerdán MC, Oliva MJ, García-Molina E, López-Ruiz M, Castro F, González-Carrillo J, de la Morena G, Valdés M (2009) Penetrance and risk profile in inherited cardiac diseases studied in a dedicated screening clinic. Am J Cardiol 104:406–410PubMedCrossRef
55.
Zurück zum Zitat Ogawa K, Nakamura Y, Terano K, Ando T, Hishitani T, Hoshino K (2009) Isolated non-compaction of the ventricular myocardium associated with long QT syndrome. Circ J 73:2169–2172PubMedCrossRef Ogawa K, Nakamura Y, Terano K, Ando T, Hishitani T, Hoshino K (2009) Isolated non-compaction of the ventricular myocardium associated with long QT syndrome. Circ J 73:2169–2172PubMedCrossRef
56.
Zurück zum Zitat Taylor GP (1992) Cardiovascular system. In: Dimmick JE, Kalousek DK (eds) Development pathology of embryo and fetus. Lippincott, Philadelphia Taylor GP (1992) Cardiovascular system. In: Dimmick JE, Kalousek DK (eds) Development pathology of embryo and fetus. Lippincott, Philadelphia
57.
Zurück zum Zitat Chen Q, Chen H, Zheng D, Kuang C, Fang H, Zou B, Zhu W, Bu G, Jin T, Wang Z, Zhang X, Chen J, Field LJ, Rubart M, Shou W, Chen Y (2009) Smad7 is required for the development and function of the heart. J Biol Chem 2(284):292–300 Chen Q, Chen H, Zheng D, Kuang C, Fang H, Zou B, Zhu W, Bu G, Jin T, Wang Z, Zhang X, Chen J, Field LJ, Rubart M, Shou W, Chen Y (2009) Smad7 is required for the development and function of the heart. J Biol Chem 2(284):292–300
58.
Zurück zum Zitat Bleyl SB, Mumford BR, Brown-Harrison MC, Pagotto LT, Carey JC, Pysher TJ, Ward K, Chin TK (1997) Xq28-linked noncompaction of the left ventricular myocardium: prenatal diagnosis and pathologic analysis of affected individuals. Am J Med Genet 72:257–265PubMedCrossRef Bleyl SB, Mumford BR, Brown-Harrison MC, Pagotto LT, Carey JC, Pysher TJ, Ward K, Chin TK (1997) Xq28-linked noncompaction of the left ventricular myocardium: prenatal diagnosis and pathologic analysis of affected individuals. Am J Med Genet 72:257–265PubMedCrossRef
59.
Zurück zum Zitat Gewillig M, Brown SC, De Catte L, Debeer A, Eyskens B, Cossey V, Van Schoubroeck D, Van Hole C, Devlieger R (2009) Premature foetal closure of the arterial duct: clinical presentations and outcome. Eur Heart J 30:1530–1536PubMedCrossRef Gewillig M, Brown SC, De Catte L, Debeer A, Eyskens B, Cossey V, Van Schoubroeck D, Van Hole C, Devlieger R (2009) Premature foetal closure of the arterial duct: clinical presentations and outcome. Eur Heart J 30:1530–1536PubMedCrossRef
60.
Zurück zum Zitat Finsterer J, Stöllberger C, Schubert B (2004) Acquired left ventricular hypertrabeculation/noncompaction in mitochondriopathy. Cardiology 102:228–230PubMedCrossRef Finsterer J, Stöllberger C, Schubert B (2004) Acquired left ventricular hypertrabeculation/noncompaction in mitochondriopathy. Cardiology 102:228–230PubMedCrossRef
61.
Zurück zum Zitat Stöllberger C, Finsterer J (2007) Disappearance of left ventricular hypertrabeculation/noncompaction after biventricular pacing in a patient with neuromuscular disorder. J Card Fail 13:211–214PubMedCrossRef Stöllberger C, Finsterer J (2007) Disappearance of left ventricular hypertrabeculation/noncompaction after biventricular pacing in a patient with neuromuscular disorder. J Card Fail 13:211–214PubMedCrossRef
62.
Zurück zum Zitat Eurlings LW, Pinto YM, Dennert RM, Bekkers SC (2009) Author reply: consider potential pitfalls, myopathy and chromosomal abnormalities when diagnosing left ventricular hypertrabeculation/noncompaction. Int J Cardiol (in press) Eurlings LW, Pinto YM, Dennert RM, Bekkers SC (2009) Author reply: consider potential pitfalls, myopathy and chromosomal abnormalities when diagnosing left ventricular hypertrabeculation/noncompaction. Int J Cardiol (in press)
63.
Zurück zum Zitat Matsumoto N, Sato Y, Kunimasa T, Matsuo S, Kato M, Yoda S, Suzuki Y, Tani S, Takahashi M, Saito S (2006) Noncompaction of the ventricular myocardium mimicking ischemic cardiomyopathy. Ann Nucl Med 20:639–641PubMedCrossRef Matsumoto N, Sato Y, Kunimasa T, Matsuo S, Kato M, Yoda S, Suzuki Y, Tani S, Takahashi M, Saito S (2006) Noncompaction of the ventricular myocardium mimicking ischemic cardiomyopathy. Ann Nucl Med 20:639–641PubMedCrossRef
64.
Zurück zum Zitat Stöllberger C, Finsterer J, Blazek G (2002) Left ventricular hypertrabeculation/noncompaction and association with additional cardiac abnormalities and neuromuscular disorders. Am J Cardiol 90:899–902PubMedCrossRef Stöllberger C, Finsterer J, Blazek G (2002) Left ventricular hypertrabeculation/noncompaction and association with additional cardiac abnormalities and neuromuscular disorders. Am J Cardiol 90:899–902PubMedCrossRef
65.
Zurück zum Zitat Cremer K, Lüdecke HJ, Ruhr F, Wieczorek D (2008) Left-ventricular non-compaction (LVNC): a clinical feature more often observed in terminal deletion 1p36 than previously expected. Eur J Med Genet 51:685–688PubMedCrossRef Cremer K, Lüdecke HJ, Ruhr F, Wieczorek D (2008) Left-ventricular non-compaction (LVNC): a clinical feature more often observed in terminal deletion 1p36 than previously expected. Eur J Med Genet 51:685–688PubMedCrossRef
66.
Zurück zum Zitat Markovic NS, Dimkovic N, Damjanovic T, Loncar G, Dimkovic S (2008) Isolated ventricular noncompaction in patients with chronic renal failure. Clin Nephrol 70:72–76PubMed Markovic NS, Dimkovic N, Damjanovic T, Loncar G, Dimkovic S (2008) Isolated ventricular noncompaction in patients with chronic renal failure. Clin Nephrol 70:72–76PubMed
67.
Zurück zum Zitat Stöllberger C, Blazek G, Wegner C, Winkler-Dworak M, Finsterer J (2010) Neuromuscular and cardiac comorbidity determine survival in 140 patients with left ventricular hypertrabeculation/noncompaction. Int J Cardiol (in press) Stöllberger C, Blazek G, Wegner C, Winkler-Dworak M, Finsterer J (2010) Neuromuscular and cardiac comorbidity determine survival in 140 patients with left ventricular hypertrabeculation/noncompaction. Int J Cardiol (in press)
68.
Zurück zum Zitat Yousef ZR, Foley PW, Khadjooi K, Chalil S, Sandman H, Mohammed NU, Leyva F (2009) Left ventricular non-compaction: clinical features and cardiovascular magnetic resonance imaging. BMC Cardiovasc Disord 9:37.ef09CrossRef Yousef ZR, Foley PW, Khadjooi K, Chalil S, Sandman H, Mohammed NU, Leyva F (2009) Left ventricular non-compaction: clinical features and cardiovascular magnetic resonance imaging. BMC Cardiovasc Disord 9:37.ef09CrossRef
69.
Zurück zum Zitat Stöllberger C, Winkler-Dworak M, Blazek G, Finsterer J (2004) Left ventricular hypertrabeculation/noncompaction with and without neuromuscular disorders. Int J Cardiol 97:89–92PubMedCrossRef Stöllberger C, Winkler-Dworak M, Blazek G, Finsterer J (2004) Left ventricular hypertrabeculation/noncompaction with and without neuromuscular disorders. Int J Cardiol 97:89–92PubMedCrossRef
70.
Zurück zum Zitat Kovacevic-Preradovic T, Jenni R, Oechslin EN, Noll G, Seifert B, Attenhofer Jost CH (2009) Isolated left ventricular noncompaction as a cause for heart failure and heart transplantation: a single center experience. Cardiology 112:158–164PubMedCrossRef Kovacevic-Preradovic T, Jenni R, Oechslin EN, Noll G, Seifert B, Attenhofer Jost CH (2009) Isolated left ventricular noncompaction as a cause for heart failure and heart transplantation: a single center experience. Cardiology 112:158–164PubMedCrossRef
71.
Zurück zum Zitat Andrews RE, Fenton MJ, Ridout DA, Burch M, British Congenital Cardiac Association (2008) New-onset heart failure due to heart muscle disease in childhood: a prospective study in the United kingdom and Ireland. Circulation 117:79–84PubMedCrossRef Andrews RE, Fenton MJ, Ridout DA, Burch M, British Congenital Cardiac Association (2008) New-onset heart failure due to heart muscle disease in childhood: a prospective study in the United kingdom and Ireland. Circulation 117:79–84PubMedCrossRef
72.
Zurück zum Zitat Steffel J, Kobza R, Namdar M, Wolber T, Brunckhorst C, Lüscher TF, Jenni R, Duru F (2009) Electrophysiological findings in patients with isolated left ventricular non-compaction. Europace 11:1193–1200PubMedCrossRef Steffel J, Kobza R, Namdar M, Wolber T, Brunckhorst C, Lüscher TF, Jenni R, Duru F (2009) Electrophysiological findings in patients with isolated left ventricular non-compaction. Europace 11:1193–1200PubMedCrossRef
73.
Zurück zum Zitat Zaragoza MV, Arbustini E, Narula J (2007) Noncompaction of the left ventricle primary cardiomyopathy with an elusive genetic etiology. Curr Opin Pediatr 19:619–627PubMedCrossRef Zaragoza MV, Arbustini E, Narula J (2007) Noncompaction of the left ventricle primary cardiomyopathy with an elusive genetic etiology. Curr Opin Pediatr 19:619–627PubMedCrossRef
74.
Zurück zum Zitat Pascal C, Lefèvre M; Société Française de Cardiologie (2005) Non-compaction of the myocardium in childhood. Arch Mal Coeur Vaiss 98443–98448 Pascal C, Lefèvre M; Société Française de Cardiologie (2005) Non-compaction of the myocardium in childhood. Arch Mal Coeur Vaiss 98443–98448
75.
Zurück zum Zitat Steffel J, Kobza R, Oechslin E, Jenni R, Duru F (2009) Electrocardiographic characteristics at initial diagnosis in patients with isolated left ventricular noncompaction. Am J Cardiol 104:984–989PubMedCrossRef Steffel J, Kobza R, Oechslin E, Jenni R, Duru F (2009) Electrocardiographic characteristics at initial diagnosis in patients with isolated left ventricular noncompaction. Am J Cardiol 104:984–989PubMedCrossRef
76.
Zurück zum Zitat Coppola G, Guttilla D, Corrado E, Falletta C, Marrone G, Farulla RA, Ciaramitaro G, Assennato P, Novo S (2009) ICD implantation in noncompaction of the left ventricular myocardium: a case report. Pacing Clin Electrophysiol 32:1092–1095PubMedCrossRef Coppola G, Guttilla D, Corrado E, Falletta C, Marrone G, Farulla RA, Ciaramitaro G, Assennato P, Novo S (2009) ICD implantation in noncompaction of the left ventricular myocardium: a case report. Pacing Clin Electrophysiol 32:1092–1095PubMedCrossRef
77.
Zurück zum Zitat Derval N, Jais P, O’Neill MD, Haissaguerre M (2009) Apparent idiopathic ventricular tachycardia associated with isolated ventricular noncompaction. Heart Rhythm 6:385–388PubMedCrossRef Derval N, Jais P, O’Neill MD, Haissaguerre M (2009) Apparent idiopathic ventricular tachycardia associated with isolated ventricular noncompaction. Heart Rhythm 6:385–388PubMedCrossRef
78.
Zurück zum Zitat Paparella G, Capulzini L, de Asmundis C, Francesconi A, Sarkozy A, Chierchia G, Brugada P (2009) Electro-anatomical mapping in a patient with isolated left ventricular non-compaction and left ventricular tachycardia. Europace 11:1227–1229PubMedCrossRef Paparella G, Capulzini L, de Asmundis C, Francesconi A, Sarkozy A, Chierchia G, Brugada P (2009) Electro-anatomical mapping in a patient with isolated left ventricular non-compaction and left ventricular tachycardia. Europace 11:1227–1229PubMedCrossRef
79.
Zurück zum Zitat Biagini E, Ragni L, Ferlito M, Pasquale F, Lofiego C, Leone O, Rocchi G, Perugini E, Zagnoni S, Branzi A, Picchio FM, Rapezzi C (2006) Different types of cardiomyopathy associated with isolated ventricular noncompaction. Am J Cardiol 98:821–824PubMedCrossRef Biagini E, Ragni L, Ferlito M, Pasquale F, Lofiego C, Leone O, Rocchi G, Perugini E, Zagnoni S, Branzi A, Picchio FM, Rapezzi C (2006) Different types of cardiomyopathy associated with isolated ventricular noncompaction. Am J Cardiol 98:821–824PubMedCrossRef
80.
Zurück zum Zitat Cavusoglu Y, Tunerir B, Birdane A, Timuralp B, Ata N, Gorenek B, Unalir A, Aslan R (2005) Transesophageal echocardiographic diagnosis of ventricular noncompaction associated with an atrial septal aneurysm in a patient with dilated cardiomyopathy of unknown etiology. Can J Cardiol 21:705–707PubMed Cavusoglu Y, Tunerir B, Birdane A, Timuralp B, Ata N, Gorenek B, Unalir A, Aslan R (2005) Transesophageal echocardiographic diagnosis of ventricular noncompaction associated with an atrial septal aneurysm in a patient with dilated cardiomyopathy of unknown etiology. Can J Cardiol 21:705–707PubMed
81.
Zurück zum Zitat Magno P, Freitas A, Gil VM (2007) Left ventricular noncompaction: case report and literature review. Rev Port Cardiol 26:1381–1391PubMed Magno P, Freitas A, Gil VM (2007) Left ventricular noncompaction: case report and literature review. Rev Port Cardiol 26:1381–1391PubMed
82.
Zurück zum Zitat Drago F, Stefano Silvetti M, Annichiarico M, Michielon G, Brancaccio G, Zanoni S, Valsecchi S (2009) Biventricular pacing in an infant with noncompaction of the ventricular myocardium, congenital AV block, and prolonged QT interval. J Interv Card Electrophysiol (in press) Drago F, Stefano Silvetti M, Annichiarico M, Michielon G, Brancaccio G, Zanoni S, Valsecchi S (2009) Biventricular pacing in an infant with noncompaction of the ventricular myocardium, congenital AV block, and prolonged QT interval. J Interv Card Electrophysiol (in press)
83.
Zurück zum Zitat Yildiz A, Ozeke O, Akyol S, Demirbag R, Yilmaz R, Gur M (2009) Biventricular myocardial noncompaction presenting with complete atrioventricular block. Int J Cardiol 132:e34–e36PubMedCrossRef Yildiz A, Ozeke O, Akyol S, Demirbag R, Yilmaz R, Gur M (2009) Biventricular myocardial noncompaction presenting with complete atrioventricular block. Int J Cardiol 132:e34–e36PubMedCrossRef
84.
Zurück zum Zitat Karamitsos TD, Bull S, Spyrou N, Neubauer S, Selvanayagam JB (2008) Tako-tsubo cardiomyopathy presenting with features of left ventricular non-compaction. Int J Cardiol 128:e34–e36PubMedCrossRef Karamitsos TD, Bull S, Spyrou N, Neubauer S, Selvanayagam JB (2008) Tako-tsubo cardiomyopathy presenting with features of left ventricular non-compaction. Int J Cardiol 128:e34–e36PubMedCrossRef
85.
Zurück zum Zitat Nil M, Mori K, Yuasa Y, Ichida F (2003) Isolated noncompaction of myocardium associated with calcification in the interventricular septum. Pediatr Cardiol 24:591–594PubMedCrossRef Nil M, Mori K, Yuasa Y, Ichida F (2003) Isolated noncompaction of myocardium associated with calcification in the interventricular septum. Pediatr Cardiol 24:591–594PubMedCrossRef
86.
Zurück zum Zitat Nemes A, Anwar AM, Caliskan K, Soliman OI, van Dalen BM, Geleijnse ML, ten Cate FJ (2008) Evaluation of left atrial systolic function in noncompaction cardiomyopathy by real-time three-dimensional echocardiography. Int J Cardiovasc Imaging 24:237–242PubMedCrossRef Nemes A, Anwar AM, Caliskan K, Soliman OI, van Dalen BM, Geleijnse ML, ten Cate FJ (2008) Evaluation of left atrial systolic function in noncompaction cardiomyopathy by real-time three-dimensional echocardiography. Int J Cardiovasc Imaging 24:237–242PubMedCrossRef
87.
Zurück zum Zitat McMahon CJ, Murchan H, Prendiville T, Burch M (2007) Long-term support with milrinone prior to cardiac transplantation in a neonate with left ventricular noncompaction cardiomyopathy. Pediatr Cardiol 28:317–318PubMedCrossRef McMahon CJ, Murchan H, Prendiville T, Burch M (2007) Long-term support with milrinone prior to cardiac transplantation in a neonate with left ventricular noncompaction cardiomyopathy. Pediatr Cardiol 28:317–318PubMedCrossRef
88.
Zurück zum Zitat Saito K, Ibuki K, Yoshimura N, Hirono K, Watanabe S, Watanabe K, Uese K, Yasukouchi S, Ichida F, Miyawaki T (2009) Successful cardiac resynchronization therapy in a 3-year-old girl with isolated left ventricular non-compaction and narrow QRS complex. Circ J 73:2173–2177PubMedCrossRef Saito K, Ibuki K, Yoshimura N, Hirono K, Watanabe S, Watanabe K, Uese K, Yasukouchi S, Ichida F, Miyawaki T (2009) Successful cardiac resynchronization therapy in a 3-year-old girl with isolated left ventricular non-compaction and narrow QRS complex. Circ J 73:2173–2177PubMedCrossRef
89.
Zurück zum Zitat Tufekcioglu O, Aras D, Yildiz A, Topaloglu S, Maden O (2008) Myocardial contraction properties along the long and short axes of the left ventricle in isolated left ventricular non-compaction: pulsed tissue Doppler echocardiography. Eur J Echocardiogr 9:344–350PubMedCrossRef Tufekcioglu O, Aras D, Yildiz A, Topaloglu S, Maden O (2008) Myocardial contraction properties along the long and short axes of the left ventricle in isolated left ventricular non-compaction: pulsed tissue Doppler echocardiography. Eur J Echocardiogr 9:344–350PubMedCrossRef
90.
Zurück zum Zitat Richards A, Mao CY, Dobson NR (2009) Left ventricular noncompaction: a rare cause of hydrops fetalis. Pediatr Cardiol 30:985–988PubMedCrossRef Richards A, Mao CY, Dobson NR (2009) Left ventricular noncompaction: a rare cause of hydrops fetalis. Pediatr Cardiol 30:985–988PubMedCrossRef
91.
Zurück zum Zitat Karabulut A, Erden I, Erden E, Cakmak M (2009) Myocardial noncompaction recognized following a transient ischemic attack. Turk Kardiyol Dern Ars 37:205–208PubMed Karabulut A, Erden I, Erden E, Cakmak M (2009) Myocardial noncompaction recognized following a transient ischemic attack. Turk Kardiyol Dern Ars 37:205–208PubMed
92.
Zurück zum Zitat Fazio G, Corrado G, Zachara E, Rapezzi C, Sulafa AK, Sutera L, Stollberger C, Sormani L, Finsterer J, Benatar A, Di Gesaro G, Visconti C, D’angelo L, Novo G, Mongiovi M, Cavusoglu Y, Baumhakel M, Drago F, Indovina G, Ferrara F, Carerj S, Pipitone S, Novo S (2008) Anticoagulant drugs in noncompaction: a mandatory therapy? J Cardiovasc Med (Hagerstown) 9:1095–1097CrossRef Fazio G, Corrado G, Zachara E, Rapezzi C, Sulafa AK, Sutera L, Stollberger C, Sormani L, Finsterer J, Benatar A, Di Gesaro G, Visconti C, D’angelo L, Novo G, Mongiovi M, Cavusoglu Y, Baumhakel M, Drago F, Indovina G, Ferrara F, Carerj S, Pipitone S, Novo S (2008) Anticoagulant drugs in noncompaction: a mandatory therapy? J Cardiovasc Med (Hagerstown) 9:1095–1097CrossRef
93.
Zurück zum Zitat Finsterer J, Stollberger C, Mölzer G, Winkler-Dworak M, Blazek G (2008) Cerebrovascular events in left ventricular hypertrabeculation/noncompaction with and without myopathy. Int J Cardiol 130:344–348PubMedCrossRef Finsterer J, Stollberger C, Mölzer G, Winkler-Dworak M, Blazek G (2008) Cerebrovascular events in left ventricular hypertrabeculation/noncompaction with and without myopathy. Int J Cardiol 130:344–348PubMedCrossRef
94.
Zurück zum Zitat Oduncu V, Akgun T, Erkol A, Mutlu B (2008) Biventricular noncompaction presenting with stroke. Eur J Cardiothorac Surg 33:737PubMedCrossRef Oduncu V, Akgun T, Erkol A, Mutlu B (2008) Biventricular noncompaction presenting with stroke. Eur J Cardiothorac Surg 33:737PubMedCrossRef
95.
Zurück zum Zitat Sahin S, Karsidag S (2009) An unusual cause of cardioembolic stroke: isolated left ventricular noncompaction. Neurologist 15:51PubMedCrossRef Sahin S, Karsidag S (2009) An unusual cause of cardioembolic stroke: isolated left ventricular noncompaction. Neurologist 15:51PubMedCrossRef
96.
Zurück zum Zitat Sir JJ, Lee B, Nah JC, Kim YL, Cho WH, Choi SK (2008) Serious cardioembolic stroke resulting from an overlooked left ventricular noncompaction. South Med J 101:969–970PubMed Sir JJ, Lee B, Nah JC, Kim YL, Cho WH, Choi SK (2008) Serious cardioembolic stroke resulting from an overlooked left ventricular noncompaction. South Med J 101:969–970PubMed
97.
Zurück zum Zitat Stöllberger C, Finsterer J (2005) Left ventricular hypertrabeculation/noncompaction and stroke or embolism. Cardiology 103:68–72PubMedCrossRef Stöllberger C, Finsterer J (2005) Left ventricular hypertrabeculation/noncompaction and stroke or embolism. Cardiology 103:68–72PubMedCrossRef
98.
Zurück zum Zitat Blessing E, Rottbauer W, Mereles D, Hosch W, Benz A, Friess H, Autschbach F, Müller M, Stremmel W, Katus H (2005) Isolated left ventricular noncompaction of the myocardium as a cause of embolic superior mesenteric artery occlusion. J Am Soc Echocardiogr 18:693PubMed Blessing E, Rottbauer W, Mereles D, Hosch W, Benz A, Friess H, Autschbach F, Müller M, Stremmel W, Katus H (2005) Isolated left ventricular noncompaction of the myocardium as a cause of embolic superior mesenteric artery occlusion. J Am Soc Echocardiogr 18:693PubMed
99.
Zurück zum Zitat Everett ME, Kirkpatrick JN, Lang RM (2005) Noncompaction of the myocardium complicated by coronary artery embolism. J Am Soc Echocardiogr 18:194–196PubMedCrossRef Everett ME, Kirkpatrick JN, Lang RM (2005) Noncompaction of the myocardium complicated by coronary artery embolism. J Am Soc Echocardiogr 18:194–196PubMedCrossRef
100.
Zurück zum Zitat Horisberger T, Lorenzana D, Noethiger CB, Jenni R (2007) Isolated noncompaction of the ventricular myocardium in a patient presenting with subarachnoid hemorrhage. Int J Cardiol 116:e98–e100PubMedCrossRef Horisberger T, Lorenzana D, Noethiger CB, Jenni R (2007) Isolated noncompaction of the ventricular myocardium in a patient presenting with subarachnoid hemorrhage. Int J Cardiol 116:e98–e100PubMedCrossRef
101.
Zurück zum Zitat Dabarian AL, Mady C, Rochitte CE, Shiozaki AA, Lemos PA, Salemi VM (2008) An unusual case of angina pectoris: a patient with isolated non compaction of the left ventricular myocardium. Eur J Echocardiogr 9:728–730PubMedCrossRef Dabarian AL, Mady C, Rochitte CE, Shiozaki AA, Lemos PA, Salemi VM (2008) An unusual case of angina pectoris: a patient with isolated non compaction of the left ventricular myocardium. Eur J Echocardiogr 9:728–730PubMedCrossRef
102.
Zurück zum Zitat Hamamichi Y, Ichida F, Hashimoto I, Uese KH, Miyawaki T, Tsukano S, Ono Y, Echigo S, Kamiya T (2001) Isolated noncompaction of the ventricular myocardium: ultrafast computed tomography and magnetic resonance imaging. Int J Cardiovasc Imaging 17:305–314PubMedCrossRef Hamamichi Y, Ichida F, Hashimoto I, Uese KH, Miyawaki T, Tsukano S, Ono Y, Echigo S, Kamiya T (2001) Isolated noncompaction of the ventricular myocardium: ultrafast computed tomography and magnetic resonance imaging. Int J Cardiovasc Imaging 17:305–314PubMedCrossRef
103.
Zurück zum Zitat Toyono M, Kondo C, Nakajima Y, Nakazawa M, Momma K, Kusakabe K (2001) Effects of carvedilol on left ventricular function, mass, and scintigraphic findings in isolated left ventricular non-compaction. Heart 86:e4PubMedCrossRef Toyono M, Kondo C, Nakajima Y, Nakazawa M, Momma K, Kusakabe K (2001) Effects of carvedilol on left ventricular function, mass, and scintigraphic findings in isolated left ventricular non-compaction. Heart 86:e4PubMedCrossRef
104.
Zurück zum Zitat Borges AC, Kivelitz D, Baumann G (2003) Isolated left ventricular non-compaction: cardiomyopathy with homogeneous transmural and heterogeneous segmental perfusion. Heart 89:e21PubMedCrossRef Borges AC, Kivelitz D, Baumann G (2003) Isolated left ventricular non-compaction: cardiomyopathy with homogeneous transmural and heterogeneous segmental perfusion. Heart 89:e21PubMedCrossRef
105.
Zurück zum Zitat Jenni R, Wyss CA, Oechslin EN, Kaufmann PA (2002) Isolated ventricular noncompaction is associated with coronary microcirculatory dysfunction. J Am Coll Cardiol 39:450–454PubMedCrossRef Jenni R, Wyss CA, Oechslin EN, Kaufmann PA (2002) Isolated ventricular noncompaction is associated with coronary microcirculatory dysfunction. J Am Coll Cardiol 39:450–454PubMedCrossRef
106.
Zurück zum Zitat Yavuzgil O, Gürgün C, Soydas Cinar C, Yüksel A (2006) Anterior myocardial infarction in an adult patient with left ventricular hypertrabeculation/noncompaction. Int J Cardiol 106:394–395PubMedCrossRef Yavuzgil O, Gürgün C, Soydas Cinar C, Yüksel A (2006) Anterior myocardial infarction in an adult patient with left ventricular hypertrabeculation/noncompaction. Int J Cardiol 106:394–395PubMedCrossRef
107.
Zurück zum Zitat D’Angeli I, Sürder D, Pedrazzini GB, Moccetti T (2009) Type B aortic dissection in a patient with unknown left ventricular non-compaction cardiomyopathy: cardiovascular magnetic resonance diagnosis. Int J Cardiol (in press) D’Angeli I, Sürder D, Pedrazzini GB, Moccetti T (2009) Type B aortic dissection in a patient with unknown left ventricular non-compaction cardiomyopathy: cardiovascular magnetic resonance diagnosis. Int J Cardiol (in press)
108.
Zurück zum Zitat Stöllberger C, Ormin V, Finsterer J (2009) Fatal outcome of aortic valve endocarditis in left ventricular hypertrabeculation/noncompaction. Int J Cardiol (in press) Stöllberger C, Ormin V, Finsterer J (2009) Fatal outcome of aortic valve endocarditis in left ventricular hypertrabeculation/noncompaction. Int J Cardiol (in press)
109.
Zurück zum Zitat Finsterer J, Stöllberger C, Feichtinger H (2008) Noncompaction and endocarditis in suspected mitochondrial disorder. Int J Cardiol 123:e45–e47PubMedCrossRef Finsterer J, Stöllberger C, Feichtinger H (2008) Noncompaction and endocarditis in suspected mitochondrial disorder. Int J Cardiol 123:e45–e47PubMedCrossRef
110.
Zurück zum Zitat Jenni R, Oechslin EN, van der Loo B (2007) Isolated ventricular non-compaction of the myocardium in adults. Heart 93:11–15PubMedCrossRef Jenni R, Oechslin EN, van der Loo B (2007) Isolated ventricular non-compaction of the myocardium in adults. Heart 93:11–15PubMedCrossRef
111.
Zurück zum Zitat Kobza R, Jenni R, Erne P, Oechslin E, Duru F (2008) Implantable cardioverter-defibrillators in patients with left ventricular noncompaction. Pacing Clin Electrophysiol 31:461–467PubMedCrossRef Kobza R, Jenni R, Erne P, Oechslin E, Duru F (2008) Implantable cardioverter-defibrillators in patients with left ventricular noncompaction. Pacing Clin Electrophysiol 31:461–467PubMedCrossRef
112.
Zurück zum Zitat Zipes DP, Camm AJ, Borggrefe M, Buxton AE, Chaitman B, Fromer M (2006) American College of Cardiology/American Heart Association Task Force; European Society of Cardiology Committee for Practice Guidelines; European Heart Rhythm Association; Heart Rhythm Society. ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (writing committee to develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death): developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Circulation 114:e385–e484 Zipes DP, Camm AJ, Borggrefe M, Buxton AE, Chaitman B, Fromer M (2006) American College of Cardiology/American Heart Association Task Force; European Society of Cardiology Committee for Practice Guidelines; European Heart Rhythm Association; Heart Rhythm Society. ACC/AHA/ESC 2006 Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (writing committee to develop Guidelines for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death): developed in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society. Circulation 114:e385–e484
113.
Zurück zum Zitat Garnier A, Girod G (2009) Cardiac re-synchronization therapy in a patient with isolated ventricular non-compaction: a case report. Eur J Echocardiogr 10:713–715PubMedCrossRef Garnier A, Girod G (2009) Cardiac re-synchronization therapy in a patient with isolated ventricular non-compaction: a case report. Eur J Echocardiogr 10:713–715PubMedCrossRef
114.
Zurück zum Zitat Oginosawa Y, Nogami A, Soejima K, Aonuma K, Kubota S, Sato T, Sugiyasu A, Yoshida K, Kowase S, Sakamaki M, Kurosaki K, Kato K (2008) Effect of cardiac resynchronization therapy in isolated ventricular noncompaction in adults: follow-up of four cases. J Cardiovasc Electrophysiol 19:935–938PubMedCrossRef Oginosawa Y, Nogami A, Soejima K, Aonuma K, Kubota S, Sato T, Sugiyasu A, Yoshida K, Kowase S, Sakamaki M, Kurosaki K, Kato K (2008) Effect of cardiac resynchronization therapy in isolated ventricular noncompaction in adults: follow-up of four cases. J Cardiovasc Electrophysiol 19:935–938PubMedCrossRef
115.
Zurück zum Zitat Stöllberger C, Blazek G, Bucher E, Finsterer J (2008) Cardiac resynchronization therapy in left ventricular hypertrabeculation/non-ompaction and myopathy. Europace 10:59–62PubMedCrossRef Stöllberger C, Blazek G, Bucher E, Finsterer J (2008) Cardiac resynchronization therapy in left ventricular hypertrabeculation/non-ompaction and myopathy. Europace 10:59–62PubMedCrossRef
116.
Zurück zum Zitat Fan KY, Chan CW, Cheng LC, Ko RL, Lam YM, Jim MH, Au TW, Ho CK, Wang EP, Chau EM, Chow WH (2009) Isolated left ventricular non-compaction: an unusual indication for heart transplantation. Hong Kong Med J 15:378–380PubMed Fan KY, Chan CW, Cheng LC, Ko RL, Lam YM, Jim MH, Au TW, Ho CK, Wang EP, Chau EM, Chow WH (2009) Isolated left ventricular non-compaction: an unusual indication for heart transplantation. Hong Kong Med J 15:378–380PubMed
117.
Zurück zum Zitat Tigen K, Karaahmet T, Gurel E, Cevik C, Basaran Y (2008) Biventricular noncompaction: a case report. Echocardiography 25:993–996PubMedCrossRef Tigen K, Karaahmet T, Gurel E, Cevik C, Basaran Y (2008) Biventricular noncompaction: a case report. Echocardiography 25:993–996PubMedCrossRef
118.
Zurück zum Zitat Aras D, Tufekcioglu O, Topaloglu S, Ergun K, Ozeke O, Yildiz A, Korkmaz S (2006) Preserved systolic function with isolated left ventricular noncompaction in an elderly patient. Eur J Echocardiogr 7:71–74PubMedCrossRef Aras D, Tufekcioglu O, Topaloglu S, Ergun K, Ozeke O, Yildiz A, Korkmaz S (2006) Preserved systolic function with isolated left ventricular noncompaction in an elderly patient. Eur J Echocardiogr 7:71–74PubMedCrossRef
119.
Zurück zum Zitat Stöllberger C, Winkler-Dworak M, Blazek G, Finsterer J (2007) Prognosis of left ventricular hypertrabeculation/noncompaction is dependent on cardiac and neuromuscular comorbidity. Int J Cardiol 121:189–193PubMedCrossRef Stöllberger C, Winkler-Dworak M, Blazek G, Finsterer J (2007) Prognosis of left ventricular hypertrabeculation/noncompaction is dependent on cardiac and neuromuscular comorbidity. Int J Cardiol 121:189–193PubMedCrossRef
120.
Zurück zum Zitat Murphy RT, Thaman R, Blanes JG, Ward D, Sevdalis E, Papra E, Kiotsekolglou A, Tome MT, Pellerin D, McKenna WJ, Elliott PM (2005) Natural history and familial characteristics of isolated left ventricular non-compaction. Eur Heart J 26:187–192PubMedCrossRef Murphy RT, Thaman R, Blanes JG, Ward D, Sevdalis E, Papra E, Kiotsekolglou A, Tome MT, Pellerin D, McKenna WJ, Elliott PM (2005) Natural history and familial characteristics of isolated left ventricular non-compaction. Eur Heart J 26:187–192PubMedCrossRef
121.
Zurück zum Zitat Punn R, Silverman NH (2010) Cardiac segmental analysis in left ventricular noncompaction: experience in a pediatric population. J Am Soc Echocardiogr 23:46–53PubMedCrossRef Punn R, Silverman NH (2010) Cardiac segmental analysis in left ventricular noncompaction: experience in a pediatric population. J Am Soc Echocardiogr 23:46–53PubMedCrossRef
122.
Zurück zum Zitat Koh C, Lee PW, Yung TC, Lun KS, Cheung YF (2009) Left ventricular noncompaction in children. Congenit Heart Dis 4:288–294PubMedCrossRef Koh C, Lee PW, Yung TC, Lun KS, Cheung YF (2009) Left ventricular noncompaction in children. Congenit Heart Dis 4:288–294PubMedCrossRef
123.
Zurück zum Zitat Lofiego C, Biagini E, Ferlito M, Pasquale F, Rocchi G, Perugini E, Leone O, Bracchetti G, Caliskan K, Branzi A, ten Cate FJ, Rapezzi C (2006) Paradoxical contributions of non-compacted and compacted segments to global left ventricular dysfunction in isolated left ventricular noncompaction. Am J Cardiol 97:738–741PubMedCrossRef Lofiego C, Biagini E, Ferlito M, Pasquale F, Rocchi G, Perugini E, Leone O, Bracchetti G, Caliskan K, Branzi A, ten Cate FJ, Rapezzi C (2006) Paradoxical contributions of non-compacted and compacted segments to global left ventricular dysfunction in isolated left ventricular noncompaction. Am J Cardiol 97:738–741PubMedCrossRef
124.
Zurück zum Zitat Tsai SF, Ebenroth ES, Hurwitz RA, Cordes TM, Schamberger MS, Batra AS (2009) Is left ventricular noncompaction in children truly an isolated lesion? Pediatr Cardiol 30:597–602PubMedCrossRef Tsai SF, Ebenroth ES, Hurwitz RA, Cordes TM, Schamberger MS, Batra AS (2009) Is left ventricular noncompaction in children truly an isolated lesion? Pediatr Cardiol 30:597–602PubMedCrossRef
125.
Zurück zum Zitat Fazio G, Pipitone S, Iacona MA, Marchì S, Mongiovì M, Zito R, Sutera L, Novo S (2007) The noncompaction of the left ventricular myocardium: our paediatric experience. J Cardiovasc Med (Hagerstown) 8:904–908CrossRef Fazio G, Pipitone S, Iacona MA, Marchì S, Mongiovì M, Zito R, Sutera L, Novo S (2007) The noncompaction of the left ventricular myocardium: our paediatric experience. J Cardiovasc Med (Hagerstown) 8:904–908CrossRef
126.
Zurück zum Zitat Marín Rodríguez C, Ossaba Vélez S, Maroto Álvaro E, Sánchez Alegre ML (2010) Lack of MR late-enhancement in left ventricular non-compaction in infants and young children. Radiologia 52:138–143PubMedCrossRef Marín Rodríguez C, Ossaba Vélez S, Maroto Álvaro E, Sánchez Alegre ML (2010) Lack of MR late-enhancement in left ventricular non-compaction in infants and young children. Radiologia 52:138–143PubMedCrossRef
127.
Zurück zum Zitat Eitel I, Fuernau G, Walther C, Razek V, Kivelitz D, Schuler G, Thiele H (2008) Delayed enhancement magnetic resonance imaging in isolated noncompaction of ventricular myocardium. Clin Res Cardiol 97:277–279PubMedCrossRef Eitel I, Fuernau G, Walther C, Razek V, Kivelitz D, Schuler G, Thiele H (2008) Delayed enhancement magnetic resonance imaging in isolated noncompaction of ventricular myocardium. Clin Res Cardiol 97:277–279PubMedCrossRef
128.
Zurück zum Zitat Celiker A, Ozkutlu S, Dilber E, Karagöz T (2005) Rhythm abnormalities in children with isolated ventricular noncompaction. Pacing Clin Electrophysiol 28:1198–1202PubMedCrossRef Celiker A, Ozkutlu S, Dilber E, Karagöz T (2005) Rhythm abnormalities in children with isolated ventricular noncompaction. Pacing Clin Electrophysiol 28:1198–1202PubMedCrossRef
129.
Zurück zum Zitat Alehan D (2004) Clinical features of isolated left ventricular noncompaction in children. Int J Cardiol 97:233–237PubMedCrossRef Alehan D (2004) Clinical features of isolated left ventricular noncompaction in children. Int J Cardiol 97:233–237PubMedCrossRef
130.
Zurück zum Zitat Klaassen S, Probst S, Oechslin E, Gerull B, Krings G, Schuler P, Greutmann M, Hürlimann D, Yegitbasi M, Pons L, Gramlich M, Drenckhahn JD, Heuser A, Berger F, Jenni R, Thierfelder L (2008) Mutations in sarcomere protein genes in left ventricular noncompaction. Circulation 117:2893–2901CrossRef Klaassen S, Probst S, Oechslin E, Gerull B, Krings G, Schuler P, Greutmann M, Hürlimann D, Yegitbasi M, Pons L, Gramlich M, Drenckhahn JD, Heuser A, Berger F, Jenni R, Thierfelder L (2008) Mutations in sarcomere protein genes in left ventricular noncompaction. Circulation 117:2893–2901CrossRef
131.
Zurück zum Zitat Hofer M, Stöllberger C, Finsterer J (2007) Acquired noncompaction associated with myopathy. Int J Cardiol 121:296–297PubMedCrossRef Hofer M, Stöllberger C, Finsterer J (2007) Acquired noncompaction associated with myopathy. Int J Cardiol 121:296–297PubMedCrossRef
132.
Zurück zum Zitat Finsterer J, Stöllberger C, Gaismayer K, Janssen B (2006) Acquired noncompaction in Duchenne muscular dystrophy. Int J Cardiol 106:420–421PubMedCrossRef Finsterer J, Stöllberger C, Gaismayer K, Janssen B (2006) Acquired noncompaction in Duchenne muscular dystrophy. Int J Cardiol 106:420–421PubMedCrossRef
133.
Zurück zum Zitat Khalid SK, Omran AS, Najm H, Godman MJ (2004) Noncompaction of the ventricular myocardium associated with mitral regurgitation and preserved ventricular systolic function. J Am Soc Echocardiogr 17:87–90CrossRef Khalid SK, Omran AS, Najm H, Godman MJ (2004) Noncompaction of the ventricular myocardium associated with mitral regurgitation and preserved ventricular systolic function. J Am Soc Echocardiogr 17:87–90CrossRef
134.
Zurück zum Zitat Hussein A, Schmaltz AA, Trowitzsch E (1999) [Isolated abnormality ("noncompaction") of the myocardium in 3 children]. Klin Padiatr 211:175–178PubMedCrossRef Hussein A, Schmaltz AA, Trowitzsch E (1999) [Isolated abnormality ("noncompaction") of the myocardium in 3 children]. Klin Padiatr 211:175–178PubMedCrossRef
135.
Zurück zum Zitat Pauli RM, Scheib-Wixted S, Cripe L, Izumo S, Sekhon GS (1999) Ventricular noncompaction and distal chromosome 5q deletion. Am J Med Genet 85:419–423PubMedCrossRef Pauli RM, Scheib-Wixted S, Cripe L, Izumo S, Sekhon GS (1999) Ventricular noncompaction and distal chromosome 5q deletion. Am J Med Genet 85:419–423PubMedCrossRef
136.
Zurück zum Zitat Steiner I, Hrubecký J, Pleskot J, Kokstejn Z (1996) Persistence of spongy myocardium with embryonic blood supply in an adult. Cardiovasc Pathol 5:47–53CrossRef Steiner I, Hrubecký J, Pleskot J, Kokstejn Z (1996) Persistence of spongy myocardium with embryonic blood supply in an adult. Cardiovasc Pathol 5:47–53CrossRef
137.
Zurück zum Zitat Neudorf UE, Hussein A, Trowitzsch E, Schmaltz AA (2001) Clinical features of isolated noncompaction of the myocardium in children. Cardiol Young 11:439–442PubMedCrossRef Neudorf UE, Hussein A, Trowitzsch E, Schmaltz AA (2001) Clinical features of isolated noncompaction of the myocardium in children. Cardiol Young 11:439–442PubMedCrossRef
138.
Zurück zum Zitat Grillo R, Pipitone S, Mongiovì M, Cipolla T, Giudice G, Gagliano S, Sperandeo V (2002) [Isolated non-compaction of left ventricle in childhood: clinical experience with 5 cases]. Ital Heart J Suppl 3:858–863PubMed Grillo R, Pipitone S, Mongiovì M, Cipolla T, Giudice G, Gagliano S, Sperandeo V (2002) [Isolated non-compaction of left ventricle in childhood: clinical experience with 5 cases]. Ital Heart J Suppl 3:858–863PubMed
139.
Zurück zum Zitat Ozkutlu S, Ayabakan C, Celiker A, Elshershari H (2002) Noncompaction of ventricular myocardium: a study of twelve patients. J Am Soc Echocardiogr 15:1523–1528PubMedCrossRef Ozkutlu S, Ayabakan C, Celiker A, Elshershari H (2002) Noncompaction of ventricular myocardium: a study of twelve patients. J Am Soc Echocardiogr 15:1523–1528PubMedCrossRef
140.
Zurück zum Zitat Wald R, Veldtman G, Golding F, Kirsh J, McCrindle B, Benson L (2004) Determinants of outcome in isolated ventricular noncompaction in childhood. Am J Cardiol 94:1581–1584PubMedCrossRef Wald R, Veldtman G, Golding F, Kirsh J, McCrindle B, Benson L (2004) Determinants of outcome in isolated ventricular noncompaction in childhood. Am J Cardiol 94:1581–1584PubMedCrossRef
141.
Zurück zum Zitat Kawasaki T, Azuma A, Taniguchi T, Asada S, Kamitani T, Kawasaki S, Matsubara H, Sugihara H (2005) Heart rate variability in adult patients with isolated left ventricular noncompaction. Int J Cardiol 99:147–150PubMedCrossRef Kawasaki T, Azuma A, Taniguchi T, Asada S, Kamitani T, Kawasaki S, Matsubara H, Sugihara H (2005) Heart rate variability in adult patients with isolated left ventricular noncompaction. Int J Cardiol 99:147–150PubMedCrossRef
142.
Zurück zum Zitat Lofiego C, Biagini E, Ferlito M, Pasquale F, Rocchi G, Perugini E, Leone O, Bracchetti G, Caliskan K, Branzi A, ten Cate FJ, Rapezzi C (2006) Paradoxical contributions of non-compacted and compacted segments to global left ventricular dysfunction in isolated left ventricular noncompaction. Am J Cardiol 97:738–741PubMedCrossRef Lofiego C, Biagini E, Ferlito M, Pasquale F, Rocchi G, Perugini E, Leone O, Bracchetti G, Caliskan K, Branzi A, ten Cate FJ, Rapezzi C (2006) Paradoxical contributions of non-compacted and compacted segments to global left ventricular dysfunction in isolated left ventricular noncompaction. Am J Cardiol 97:738–741PubMedCrossRef
Metadaten
Titel
Left ventricular non-compaction and its cardiac and neurologic implications
verfasst von
Josef Finsterer
Publikationsdatum
01.11.2010
Verlag
Springer US
Erschienen in
Heart Failure Reviews / Ausgabe 6/2010
Print ISSN: 1382-4147
Elektronische ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-010-9175-5

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