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Erschienen in: Heart Failure Reviews 6/2010

01.11.2010

Stem cells in the diabetic infarcted heart

verfasst von: Carley E. Glass, Pawan K. Singal, Dinender K. Singla

Erschienen in: Heart Failure Reviews | Ausgabe 6/2010

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Abstract

Diabetes mellitus is one of the leading causes of death, and the majority of these deaths are associated with cardiovascular diseases. Development and progression of myocardial infarction leading to heart failure is much more complex and multifactorial in diabetics compared with non-diabetics. Despite significant advances in pharmacological interventions and surgical techniques, the disease progression leading to diabetic end-stage heart failure remains very high. Recently, cell therapy has gained much attention as an alternative approach to treat various heart diseases. However, transplanted stem cell studies in diabetic animal models are very limited. In this review, we discuss the pathogenesis of the diabetic infarcted heart and the potential of stem cell therapy to repair and regenerate.
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Metadaten
Titel
Stem cells in the diabetic infarcted heart
verfasst von
Carley E. Glass
Pawan K. Singal
Dinender K. Singla
Publikationsdatum
01.11.2010
Verlag
Springer US
Erschienen in
Heart Failure Reviews / Ausgabe 6/2010
Print ISSN: 1382-4147
Elektronische ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-010-9172-8

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