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Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy 1/2016

01.01.2016 | Hip

Femoro-acetabular impingement clinical research: is a composite outcome the answer?

verfasst von: Olufemi R. Ayeni, Mikael Sansone, Darren de Sa, Nicole Simunovic, Asheesh Bedi, Bryan T. Kelly, Forough Farrokhyar, Jon Karlsson

Erschienen in: Knee Surgery, Sports Traumatology, Arthroscopy | Ausgabe 1/2016

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Abstract

Femoro-acetabular impingement (FAI) is increasingly recognized as an important cause of hip pain in the young adult. However, the methods of evaluating the efficacy of surgical intervention are often not validated and/or inconsistently reported. Important clinical, gait, radiographic and biomarker outcomes are discussed. This article (1) presents the rationale for considering a composite outcome for FAI patients; (2) examines a variety of important end points currently used to evaluate FAI surgery; (3) discusses a strategy to generate a composite outcome by combining these end points; and (4) highlights the challenges and current areas of controversy that such an approach to evaluating symptomatic FAI patients may present.
Literatur
1.
Zurück zum Zitat Abrams GD, Safran MR, Shapiro LM, Maloney WJ, Goodman SB, Huddleston JI, Bellino MJ, Scuderi GJ (2014) Fibronectin-aggrecan complex as a marker for cartilage degradation in non-arthritic hips. Knee Surg Sports Traumatol Arthrosc 22:768–773PubMedCrossRef Abrams GD, Safran MR, Shapiro LM, Maloney WJ, Goodman SB, Huddleston JI, Bellino MJ, Scuderi GJ (2014) Fibronectin-aggrecan complex as a marker for cartilage degradation in non-arthritic hips. Knee Surg Sports Traumatol Arthrosc 22:768–773PubMedCrossRef
2.
Zurück zum Zitat Agricola R, Bessems JH, Ginai AZ, Heijboer MP, van der Heijden RA, Verhaar JA, Weinans H, Waarsing JH (2012) The development of cam-type deformity in adolescent and young male soccer players. Am J Sports Med 40:1099–1106PubMedCrossRef Agricola R, Bessems JH, Ginai AZ, Heijboer MP, van der Heijden RA, Verhaar JA, Weinans H, Waarsing JH (2012) The development of cam-type deformity in adolescent and young male soccer players. Am J Sports Med 40:1099–1106PubMedCrossRef
3.
Zurück zum Zitat Alradwan H, Khan M, Hamel-Smith Grassby M, Bedi A, Philippon MJ, Ayeni OR (2014) Gait and lower extremity kinematic analysis as an outcome measure after femoroacetabular impingement surgery. Arthroscopy. doi:10.1016/j.arthro.2014.06.016 Alradwan H, Khan M, Hamel-Smith Grassby M, Bedi A, Philippon MJ, Ayeni OR (2014) Gait and lower extremity kinematic analysis as an outcome measure after femoroacetabular impingement surgery. Arthroscopy. doi:10.​1016/​j.​arthro.​2014.​06.​016
4.
Zurück zum Zitat Ayeni OR, Banga K, Bhandari M, Maizlin Z, de Sa D, Golev D, Harish S, Farrokhyar F (2014) Femoroacetabular impingement in elite ice hockey players. Knee Surg Sports Traumatol Arthrosc 22:920–925PubMedCrossRef Ayeni OR, Banga K, Bhandari M, Maizlin Z, de Sa D, Golev D, Harish S, Farrokhyar F (2014) Femoroacetabular impingement in elite ice hockey players. Knee Surg Sports Traumatol Arthrosc 22:920–925PubMedCrossRef
5.
Zurück zum Zitat Ayeni OR, Chan K, Al-Asiri J, Chien T, Sprague S, Liew S, Bhandari M (2013) Sources and quality of literature addressing femoroacetabular impingement. Knee Surg Sports Traumatol Arthrosc 21:415–419PubMedCrossRef Ayeni OR, Chan K, Al-Asiri J, Chien T, Sprague S, Liew S, Bhandari M (2013) Sources and quality of literature addressing femoroacetabular impingement. Knee Surg Sports Traumatol Arthrosc 21:415–419PubMedCrossRef
6.
Zurück zum Zitat Beaulé PE, Hynes K, Parker G, Kemp KA (2012) Can the alpha angle assessment of cam impingement predict acetabular cartilage delamination? Clin Orthop Relat Res 470:3361–3367PubMedPubMedCentralCrossRef Beaulé PE, Hynes K, Parker G, Kemp KA (2012) Can the alpha angle assessment of cam impingement predict acetabular cartilage delamination? Clin Orthop Relat Res 470:3361–3367PubMedPubMedCentralCrossRef
7.
Zurück zum Zitat Beck M, Kalhor M, Leunig M, Ganz R (2005) Hip morphology influences the pattern of damage to the acetabular cartilage: femoroacetabular impingement as a cause of early osteoarthritis of the hip. J Bone Joint Surg Br 87:1012–1018PubMedCrossRef Beck M, Kalhor M, Leunig M, Ganz R (2005) Hip morphology influences the pattern of damage to the acetabular cartilage: femoroacetabular impingement as a cause of early osteoarthritis of the hip. J Bone Joint Surg Br 87:1012–1018PubMedCrossRef
8.
Zurück zum Zitat Bedi A, Lynch EB, Sibilsky Enselman ER, Davis ME, Dewolf PD, Makki TA, Kelly BT, Larson CM, Henning PT, Mendias CL (2013) Elevation in circulating biomarkers of cartilage damage and inflammation in athletes with femoroacetabular impingement. Am J Sports Med 41:2585–2590PubMedPubMedCentralCrossRef Bedi A, Lynch EB, Sibilsky Enselman ER, Davis ME, Dewolf PD, Makki TA, Kelly BT, Larson CM, Henning PT, Mendias CL (2013) Elevation in circulating biomarkers of cartilage damage and inflammation in athletes with femoroacetabular impingement. Am J Sports Med 41:2585–2590PubMedPubMedCentralCrossRef
9.
Zurück zum Zitat Bittersohl B, Hosalkar HS, Kim YJ, Werlen S, Trattnig S, Siebenrock KA, Mamisch TC (2010) T1 assessment of hip joint cartilage following intra-articular gadolinium injection: a pilot study. Magn Reson Med 64:1200–1207PubMedCrossRef Bittersohl B, Hosalkar HS, Kim YJ, Werlen S, Trattnig S, Siebenrock KA, Mamisch TC (2010) T1 assessment of hip joint cartilage following intra-articular gadolinium injection: a pilot study. Magn Reson Med 64:1200–1207PubMedCrossRef
10.
Zurück zum Zitat Bozic KJ, Chan V, Valone FH 3rd, Feeley BT, Vail TP (2013) Trends in hip arthroscopy utilization in the United States. J Arthroplasty 28:140–143PubMedCrossRef Bozic KJ, Chan V, Valone FH 3rd, Feeley BT, Vail TP (2013) Trends in hip arthroscopy utilization in the United States. J Arthroplasty 28:140–143PubMedCrossRef
11.
Zurück zum Zitat Clohisy JC, Dobson MA, Robison JF, Warth LC, Zheng J, Liu SS, Yehyawi TM, Callaghan JJ (2011) Radiographic structural abnormalities associated with premature, natural hip-joint failure. J Bone Joint Surg Am 93(Suppl 2):3–9PubMedCrossRef Clohisy JC, Dobson MA, Robison JF, Warth LC, Zheng J, Liu SS, Yehyawi TM, Callaghan JJ (2011) Radiographic structural abnormalities associated with premature, natural hip-joint failure. J Bone Joint Surg Am 93(Suppl 2):3–9PubMedCrossRef
12.
Zurück zum Zitat Clohisy JC, Carlisle JC, Trousdale R, Kim YJ, Beaule PE, Morgan P, Steger-May K, Schoenecker PL, Millis M (2009) Radiographic evaluation of the hip has limited reliability. Clin Orthop Relat Res 467:666–675PubMedPubMedCentralCrossRef Clohisy JC, Carlisle JC, Trousdale R, Kim YJ, Beaule PE, Morgan P, Steger-May K, Schoenecker PL, Millis M (2009) Radiographic evaluation of the hip has limited reliability. Clin Orthop Relat Res 467:666–675PubMedPubMedCentralCrossRef
13.
Zurück zum Zitat Colvin AC, Harrast J, Harner C (2012) Trends in hip arthroscopy. J Bone Joint Surg Am 94:e23PubMed Colvin AC, Harrast J, Harner C (2012) Trends in hip arthroscopy. J Bone Joint Surg Am 94:e23PubMed
14.
Zurück zum Zitat de Sa D, Cargnelli S, Catapano M, Bedi A, Simunovic N, Burrow S, Ayeni OR (2014) Femoroacetabular impingement in skeletally immature patients: a systematic review examining indications, outcomes, and complications of open and arthroscopic treatment. Arthroscopy. doi:10.1016/j.arthro.2014.07.030 de Sa D, Cargnelli S, Catapano M, Bedi A, Simunovic N, Burrow S, Ayeni OR (2014) Femoroacetabular impingement in skeletally immature patients: a systematic review examining indications, outcomes, and complications of open and arthroscopic treatment. Arthroscopy. doi:10.​1016/​j.​arthro.​2014.​07.​030
15.
Zurück zum Zitat de Sa D, Urquhart N, Philippon M, Ye JE, Simunovic N, Ayeni OR (2014) Alpha angle correction in femoroacetabular impingement. Knee Surg Sports Traumatol Arthrosc 22:812–821PubMedCrossRef de Sa D, Urquhart N, Philippon M, Ye JE, Simunovic N, Ayeni OR (2014) Alpha angle correction in femoroacetabular impingement. Knee Surg Sports Traumatol Arthrosc 22:812–821PubMedCrossRef
16.
Zurück zum Zitat Eijer H, Myers SR, Ganz R (2001) Anterior femoroacetabular impingement after femoral neck fractures. J Orthop Trauma 15:475–481PubMedCrossRef Eijer H, Myers SR, Ganz R (2001) Anterior femoroacetabular impingement after femoral neck fractures. J Orthop Trauma 15:475–481PubMedCrossRef
17.
Zurück zum Zitat Freemantle N, Calvert M, Wood J, Eastaugh J, Griffin C (2003) Composite outcomes in randomized trials: greater precision but with greater uncertainty? JAMA 289:2554–2559PubMedCrossRef Freemantle N, Calvert M, Wood J, Eastaugh J, Griffin C (2003) Composite outcomes in randomized trials: greater precision but with greater uncertainty? JAMA 289:2554–2559PubMedCrossRef
18.
Zurück zum Zitat Ganz R, Parvizi J, Beck M, Leunig M, Notzli H, Siebenrock KA (2003) Femoroacetabular impingement: a cause for osteoarthritis of the hip. Clin Orthop Relat Res 417:112–120PubMed Ganz R, Parvizi J, Beck M, Leunig M, Notzli H, Siebenrock KA (2003) Femoroacetabular impingement: a cause for osteoarthritis of the hip. Clin Orthop Relat Res 417:112–120PubMed
19.
Zurück zum Zitat Garvican ER, Vaughan-Thomas A, Clegg PD, Innes JF (2010) Biomarkers of cartilage turnover. Part 2: non-collagenous markers. Vet J 185:43–49PubMedCrossRef Garvican ER, Vaughan-Thomas A, Clegg PD, Innes JF (2010) Biomarkers of cartilage turnover. Part 2: non-collagenous markers. Vet J 185:43–49PubMedCrossRef
20.
Zurück zum Zitat Gosvig KK, Jacobsen S, Sonne-Holm S, Palm H, Troelsen A (2010) Prevalence of malformations of the hip joint and their relationship to sex, groin pain, and risk of osteoarthritis: a population-based survey. J Bone Joint Surg Am 92:1162–1169PubMedCrossRef Gosvig KK, Jacobsen S, Sonne-Holm S, Palm H, Troelsen A (2010) Prevalence of malformations of the hip joint and their relationship to sex, groin pain, and risk of osteoarthritis: a population-based survey. J Bone Joint Surg Am 92:1162–1169PubMedCrossRef
21.
Zurück zum Zitat Gosvig KK, Jacobsen S, Sonne-Holm S, Gebuhr P (2008) The prevalence of cam-type deformity of the hip joint: a survey of 4151 subjects of the Copenhagen Osteoarthritis Study. Acta Radiol 49:436–441PubMedCrossRef Gosvig KK, Jacobsen S, Sonne-Holm S, Gebuhr P (2008) The prevalence of cam-type deformity of the hip joint: a survey of 4151 subjects of the Copenhagen Osteoarthritis Study. Acta Radiol 49:436–441PubMedCrossRef
22.
Zurück zum Zitat Hack K, Di Primio G, Rakhra K, Beaule PE (2010) Prevalence of cam-type femoroacetabular impingement morphology in asymptomatic volunteers. J Bone Joint Surg Am 92:2436–2444PubMedCrossRef Hack K, Di Primio G, Rakhra K, Beaule PE (2010) Prevalence of cam-type femoroacetabular impingement morphology in asymptomatic volunteers. J Bone Joint Surg Am 92:2436–2444PubMedCrossRef
23.
Zurück zum Zitat Harris-Hayes M, McDonough CM, Leunig M, Lee CB, Callaghan JJ, Roos EM (2013) Clinical outcomes assessment in clinical trials to assess treatment of femoroacetabular impingement: use of patient-reported outcome measures. J Am Acad Orthop Surg 21(Suppl. 1):S39–S46PubMedPubMedCentralCrossRef Harris-Hayes M, McDonough CM, Leunig M, Lee CB, Callaghan JJ, Roos EM (2013) Clinical outcomes assessment in clinical trials to assess treatment of femoroacetabular impingement: use of patient-reported outcome measures. J Am Acad Orthop Surg 21(Suppl. 1):S39–S46PubMedPubMedCentralCrossRef
24.
Zurück zum Zitat Hashimoto S, Rai MF, Gill CS, Zhang Z, Sandell LJ, Clohisy JC (2013) Molecular characterization of articular cartilage from young adults with femoroacetabular impingement. J Bone Joint Surg Am 95:1457–1464PubMedPubMedCentralCrossRef Hashimoto S, Rai MF, Gill CS, Zhang Z, Sandell LJ, Clohisy JC (2013) Molecular characterization of articular cartilage from young adults with femoroacetabular impingement. J Bone Joint Surg Am 95:1457–1464PubMedPubMedCentralCrossRef
25.
Zurück zum Zitat Haviv B, Burg A, Velkes S, Salai M, Dudkiewicz I (2011) Trends in femoroacetabular impingement research over 11 years. Orthopedics 34:353PubMed Haviv B, Burg A, Velkes S, Salai M, Dudkiewicz I (2011) Trends in femoroacetabular impingement research over 11 years. Orthopedics 34:353PubMed
26.
Zurück zum Zitat Hetaimish BM, Khan M, Crouch S, Simunovic N, Bedi A, Mohtadi N, Bhandari M, Ayeni OR (2013) Consistency of reported outcomes after arthroscopic management of femoroacetabular impingement. Arthroscopy 29:780–787PubMedCrossRef Hetaimish BM, Khan M, Crouch S, Simunovic N, Bedi A, Mohtadi N, Bhandari M, Ayeni OR (2013) Consistency of reported outcomes after arthroscopic management of femoroacetabular impingement. Arthroscopy 29:780–787PubMedCrossRef
27.
Zurück zum Zitat Hoang-Kim A, Miclau T, Goldhahn J, Nijman TH, Poolman RW (2014) Patient-important outcome for the assessment of fracture repair. Injury 45(Suppl. 2):S44–S48PubMedCrossRef Hoang-Kim A, Miclau T, Goldhahn J, Nijman TH, Poolman RW (2014) Patient-important outcome for the assessment of fracture repair. Injury 45(Suppl. 2):S44–S48PubMedCrossRef
28.
Zurück zum Zitat Homandberg GA, Davis G, Maniglia C, Shrikhande A (1997) Cartilage chondrolysis by fibronectin fragments causes cleavage of aggrecan at the same site as found in osteoarthritic cartilage. Osteoarthr Cartil 5:450–453PubMedCrossRef Homandberg GA, Davis G, Maniglia C, Shrikhande A (1997) Cartilage chondrolysis by fibronectin fragments causes cleavage of aggrecan at the same site as found in osteoarthritic cartilage. Osteoarthr Cartil 5:450–453PubMedCrossRef
29.
30.
Zurück zum Zitat Johnston TL, Schenker ML, Briggs KK, Philippon MJ (2008) Relationship between offset angle alpha and hip chondral injury in femoroacetabular impingement. Arthroscopy 24:669–675PubMedCrossRef Johnston TL, Schenker ML, Briggs KK, Philippon MJ (2008) Relationship between offset angle alpha and hip chondral injury in femoroacetabular impingement. Arthroscopy 24:669–675PubMedCrossRef
31.
Zurück zum Zitat Jonasson P, Baranto A, Karlsson J, Sward L, Sansone M, Thomee C, Ahlden M, Thomee R (2014) A standardised outcome measure of pain, symptoms and physical function in patients with hip and groin disability due to femoro-acetabular impingement: cross-cultural adaptation and validation of the International Hip Outcome Tool (iHOT12) in Swedish. Knee Surg Sports Traumatol Arthrosc 22:826–834PubMedCrossRef Jonasson P, Baranto A, Karlsson J, Sward L, Sansone M, Thomee C, Ahlden M, Thomee R (2014) A standardised outcome measure of pain, symptoms and physical function in patients with hip and groin disability due to femoro-acetabular impingement: cross-cultural adaptation and validation of the International Hip Outcome Tool (iHOT12) in Swedish. Knee Surg Sports Traumatol Arthrosc 22:826–834PubMedCrossRef
32.
Zurück zum Zitat Kohl S, Hosalkar HS, Mainil-Varlet P, Krueger A, Buechler L, Siebenrock K (2011) Histology of damaged acetabular cartilage in symptomatic femoroacetabular impingement: an observational analysis. Hip Int 21:154–162PubMedCrossRef Kohl S, Hosalkar HS, Mainil-Varlet P, Krueger A, Buechler L, Siebenrock K (2011) Histology of damaged acetabular cartilage in symptomatic femoroacetabular impingement: an observational analysis. Hip Int 21:154–162PubMedCrossRef
33.
Zurück zum Zitat Lamy A, Devereaux PJ, Prabhakaran D, Taggart DP, Hu S, Paolasso E, Straka Z, Piegas LS, Akar AR, Jain AR, Noiseux N, Padmanabhan C, Bahamondes JC, Novick RJ, Vaijyanath P, Reddy SK, Tao L, Olavegogeascoechea PA, Airan B, Sulling TA, Whitlock RP, Ou Y, Pogue J, Chrolavicius S, Yusuf S, CORONARY Investigators (2013) Effects of off-pump and on-pump coronary-artery bypass grafting at 1 year. N Engl J Med 368:1179–1188PubMedCrossRef Lamy A, Devereaux PJ, Prabhakaran D, Taggart DP, Hu S, Paolasso E, Straka Z, Piegas LS, Akar AR, Jain AR, Noiseux N, Padmanabhan C, Bahamondes JC, Novick RJ, Vaijyanath P, Reddy SK, Tao L, Olavegogeascoechea PA, Airan B, Sulling TA, Whitlock RP, Ou Y, Pogue J, Chrolavicius S, Yusuf S, CORONARY Investigators (2013) Effects of off-pump and on-pump coronary-artery bypass grafting at 1 year. N Engl J Med 368:1179–1188PubMedCrossRef
34.
Zurück zum Zitat Lamy A, Devereaux PJ, Prabhakaran D, Taggart DP, Hu S, Paolasso E, Straka Z, Piegas LS, Akar AR, Jain AR, Noiseux N, Padmanabhan C, Bahamondes JC, Novick RJ, Vaijyanath P, Reddy S, Tao L, Olavegogeascoechea PA, Airan B, Sulling TA, Whitlock RP, Ou Y, Ng J, Chrolavicius S, Yusuf S, CORONARY Investigators (2012) Off-pump or on-pump coronary-artery bypass grafting at 30 days. N Engl J Med 366:1489–1497PubMedCrossRef Lamy A, Devereaux PJ, Prabhakaran D, Taggart DP, Hu S, Paolasso E, Straka Z, Piegas LS, Akar AR, Jain AR, Noiseux N, Padmanabhan C, Bahamondes JC, Novick RJ, Vaijyanath P, Reddy S, Tao L, Olavegogeascoechea PA, Airan B, Sulling TA, Whitlock RP, Ou Y, Ng J, Chrolavicius S, Yusuf S, CORONARY Investigators (2012) Off-pump or on-pump coronary-artery bypass grafting at 30 days. N Engl J Med 366:1489–1497PubMedCrossRef
35.
Zurück zum Zitat Larson CM, Giveans MR (2008) Arthroscopic management of femoroacetabular impingement: early outcomes measures. Arthroscopy 24:540–546PubMedCrossRef Larson CM, Giveans MR (2008) Arthroscopic management of femoroacetabular impingement: early outcomes measures. Arthroscopy 24:540–546PubMedCrossRef
36.
Zurück zum Zitat Leunig M, Casillas MM, Hamlet M, Hersche O, Notzli H, Slongo T, Ganz R (2000) Slipped capital femoral epiphysis: early mechanical damage to the acetabular cartilage by a prominent femoral metaphysis. Acta Orthop Scand 71:370–375PubMedCrossRef Leunig M, Casillas MM, Hamlet M, Hersche O, Notzli H, Slongo T, Ganz R (2000) Slipped capital femoral epiphysis: early mechanical damage to the acetabular cartilage by a prominent femoral metaphysis. Acta Orthop Scand 71:370–375PubMedCrossRef
37.
Zurück zum Zitat Mannion AF, Impellizzeri FM, Naal FD, Leunig M (2013) Fulfilment of patient-rated expectations predicts the outcome of surgery for femoroacetabular impingement. Osteoarthr Cartil 21:44–50PubMedCrossRef Mannion AF, Impellizzeri FM, Naal FD, Leunig M (2013) Fulfilment of patient-rated expectations predicts the outcome of surgery for femoroacetabular impingement. Osteoarthr Cartil 21:44–50PubMedCrossRef
38.
Zurück zum Zitat Martin RL, Kelly BT, Philippon MJ (2006) Evidence of validity for the hip outcome score. Arthroscopy 22:1304–1311PubMedCrossRef Martin RL, Kelly BT, Philippon MJ (2006) Evidence of validity for the hip outcome score. Arthroscopy 22:1304–1311PubMedCrossRef
39.
Zurück zum Zitat Maruyama M, Feinberg JR, Capello WN, D’Antonio JA (2001) The Frank Stinchfield award: morphologic features of the acetabulum and femur: anteversion angle and implant positioning. Clin Orthop Relat Res 393:52–65PubMedCrossRef Maruyama M, Feinberg JR, Capello WN, D’Antonio JA (2001) The Frank Stinchfield award: morphologic features of the acetabulum and femur: anteversion angle and implant positioning. Clin Orthop Relat Res 393:52–65PubMedCrossRef
40.
Zurück zum Zitat Matzat SJ, van Tiel J, Gold GE, Oei EH (2013) Quantitative MRI techniques of cartilage composition. Quant Imaging Med Surg 3:162–174PubMedPubMedCentral Matzat SJ, van Tiel J, Gold GE, Oei EH (2013) Quantitative MRI techniques of cartilage composition. Quant Imaging Med Surg 3:162–174PubMedPubMedCentral
41.
Zurück zum Zitat Mohtadi NG, Griffin DR, Pedersen ME, Chan D, Safran MR, Parsons N, Sekiya JK, Kelly BT, Werle JR, Leunig M, McCarthy JC, Martin HD, Byrd JW, Philippon MJ, Martin RL, Guanche CA, Clohisy JC, Sampson TG, Kocher MS, Larson CM, Multicenter Arthroscopy of the Hip Outcomes Research Network (2012) The development and validation of a self-administered quality-of-life outcome measure for young, active patients with symptomatic hip disease: the International Hip Outcome Tool (iHOT-33). Arthroscopy 28:595–605; quiz 606-10.e1 Mohtadi NG, Griffin DR, Pedersen ME, Chan D, Safran MR, Parsons N, Sekiya JK, Kelly BT, Werle JR, Leunig M, McCarthy JC, Martin HD, Byrd JW, Philippon MJ, Martin RL, Guanche CA, Clohisy JC, Sampson TG, Kocher MS, Larson CM, Multicenter Arthroscopy of the Hip Outcomes Research Network (2012) The development and validation of a self-administered quality-of-life outcome measure for young, active patients with symptomatic hip disease: the International Hip Outcome Tool (iHOT-33). Arthroscopy 28:595–605; quiz 606-10.e1
42.
Zurück zum Zitat Montori VM, Permanyer-Miralda G, Ferreira-Gonzalez I, Busse JW, Pacheco-Huergo V, Bryant D, Alonso J, Akl EA, Domingo-Salvany A, Mills E, Wu P, Schunemann HJ, Jaeschke R, Guyatt GH (2005) Validity of composite end points in clinical trials. BMJ 330:594–596PubMedPubMedCentralCrossRef Montori VM, Permanyer-Miralda G, Ferreira-Gonzalez I, Busse JW, Pacheco-Huergo V, Bryant D, Alonso J, Akl EA, Domingo-Salvany A, Mills E, Wu P, Schunemann HJ, Jaeschke R, Guyatt GH (2005) Validity of composite end points in clinical trials. BMJ 330:594–596PubMedPubMedCentralCrossRef
43.
Zurück zum Zitat Naal FD, Miozzari HH, Kelly BT, Magennis EM, Leunig M, Noetzli HP (2013) The Hip Sports Activity Scale (HSAS) for patients with femoroacetabular impingement. Hip Int 23:204–211PubMedCrossRef Naal FD, Miozzari HH, Kelly BT, Magennis EM, Leunig M, Noetzli HP (2013) The Hip Sports Activity Scale (HSAS) for patients with femoroacetabular impingement. Hip Int 23:204–211PubMedCrossRef
44.
Zurück zum Zitat Philippon MJ, Maxwell RB, Johnston TL, Schenker M, Briggs KK (2007) Clinical presentation of femoroacetabular impingement. Knee Surg Sports Traumatol Arthrosc 15:1041–1047PubMedCrossRef Philippon MJ, Maxwell RB, Johnston TL, Schenker M, Briggs KK (2007) Clinical presentation of femoroacetabular impingement. Knee Surg Sports Traumatol Arthrosc 15:1041–1047PubMedCrossRef
45.
Zurück zum Zitat Philippon MJ, Stubbs AJ, Schenker ML, Maxwell RB, Ganz R, Leunig M (2007) Arthroscopic management of femoroacetabular impingement: osteoplasty technique and literature review. Am J Sports Med 35:1571–1580PubMedCrossRef Philippon MJ, Stubbs AJ, Schenker ML, Maxwell RB, Ganz R, Leunig M (2007) Arthroscopic management of femoroacetabular impingement: osteoplasty technique and literature review. Am J Sports Med 35:1571–1580PubMedCrossRef
46.
Zurück zum Zitat Poolman RW, Swiontkowski MF, Fairbank JC, Schemitsch EH, Sprague S, de Vet HC (2009) Outcome instruments: rationale for their use. J Bone Joint Surg Am 91(Suppl 3):41–49PubMedPubMedCentralCrossRef Poolman RW, Swiontkowski MF, Fairbank JC, Schemitsch EH, Sprague S, de Vet HC (2009) Outcome instruments: rationale for their use. J Bone Joint Surg Am 91(Suppl 3):41–49PubMedPubMedCentralCrossRef
47.
Zurück zum Zitat Posey KL, Hecht JT (2008) The role of cartilage oligomeric matrix protein (COMP) in skeletal disease. Curr Drug Targets 9:869–877PubMedCrossRef Posey KL, Hecht JT (2008) The role of cartilage oligomeric matrix protein (COMP) in skeletal disease. Curr Drug Targets 9:869–877PubMedCrossRef
48.
Zurück zum Zitat Rab GT (1999) The geometry of slipped capital femoral epiphysis: implications for movement, impingement, and corrective osteotomy. J Pediatr Orthop 19:419–424PubMedCrossRef Rab GT (1999) The geometry of slipped capital femoral epiphysis: implications for movement, impingement, and corrective osteotomy. J Pediatr Orthop 19:419–424PubMedCrossRef
49.
Zurück zum Zitat Ranawat AS, Schulz B, Baumbach SF, Meftah M, Ganz R, Leunig M (2011) Radiographic predictors of hip pain in femoroacetabular impingement. HSS J 7:115–119PubMedPubMedCentralCrossRef Ranawat AS, Schulz B, Baumbach SF, Meftah M, Ganz R, Leunig M (2011) Radiographic predictors of hip pain in femoroacetabular impingement. HSS J 7:115–119PubMedPubMedCentralCrossRef
50.
Zurück zum Zitat Rylander J, Shu B, Favre J, Safran M, Andriacchi T (2013) Functional testing provides unique insights into the pathomechanics of femoroacetabular impingement and an objective basis for evaluating treatment outcome. J Orthop Res 31:1461–1468PubMedCrossRef Rylander J, Shu B, Favre J, Safran M, Andriacchi T (2013) Functional testing provides unique insights into the pathomechanics of femoroacetabular impingement and an objective basis for evaluating treatment outcome. J Orthop Res 31:1461–1468PubMedCrossRef
51.
Zurück zum Zitat Rylander JH, Shu B, Andriacchi TP, Safran MR (2011) Preoperative and postoperative sagittal plane hip kinematics in patients with femoroacetabular impingement during level walking. Am J Sports Med 39(Suppl):36S–42SPubMedCrossRef Rylander JH, Shu B, Andriacchi TP, Safran MR (2011) Preoperative and postoperative sagittal plane hip kinematics in patients with femoroacetabular impingement during level walking. Am J Sports Med 39(Suppl):36S–42SPubMedCrossRef
52.
Zurück zum Zitat Saksena S, Slee A, Waldo AL, Freemantle N, Reynolds M, Rosenberg Y, Rathod S, Grant S, Thomas E, Wyse DG (2011) Cardiovascular outcomes in the AFFIRM Trial (Atrial Fibrillation Follow-Up Investigation of Rhythm Management). An assessment of individual antiarrhythmic drug therapies compared with rate control with propensity score-matched analyses. J Am Coll Cardiol 58:1975–1985PubMedPubMedCentralCrossRef Saksena S, Slee A, Waldo AL, Freemantle N, Reynolds M, Rosenberg Y, Rathod S, Grant S, Thomas E, Wyse DG (2011) Cardiovascular outcomes in the AFFIRM Trial (Atrial Fibrillation Follow-Up Investigation of Rhythm Management). An assessment of individual antiarrhythmic drug therapies compared with rate control with propensity score-matched analyses. J Am Coll Cardiol 58:1975–1985PubMedPubMedCentralCrossRef
53.
Zurück zum Zitat Sansone M, Ahlden M, Jonasson P, Thomee C, Sward L, Baranto A, Karlsson J, Thomee R (2014) A Swedish hip arthroscopy registry: demographics and development. Knee Surg Sports Traumatol Arthrosc 22:774–780PubMedCrossRef Sansone M, Ahlden M, Jonasson P, Thomee C, Sward L, Baranto A, Karlsson J, Thomee R (2014) A Swedish hip arthroscopy registry: demographics and development. Knee Surg Sports Traumatol Arthrosc 22:774–780PubMedCrossRef
54.
Zurück zum Zitat Siebenrock KA, Ferner F, Noble PC, Santore RF, Werlen S, Mamisch TC (2011) The cam-type deformity of the proximal femur arises in childhood in response to vigorous sporting activity. Clin Orthop Relat Res 469:3229–3240PubMedPubMedCentralCrossRef Siebenrock KA, Ferner F, Noble PC, Santore RF, Werlen S, Mamisch TC (2011) The cam-type deformity of the proximal femur arises in childhood in response to vigorous sporting activity. Clin Orthop Relat Res 469:3229–3240PubMedPubMedCentralCrossRef
55.
Zurück zum Zitat Siebenrock KA, Wahab KH, Werlen S, Kalhor M, Leunig M, Ganz R (2004) Abnormal extension of the femoral head epiphysis as a cause of cam impingement. Clin Orthop Relat Res 418:54–60PubMedCrossRef Siebenrock KA, Wahab KH, Werlen S, Kalhor M, Leunig M, Ganz R (2004) Abnormal extension of the femoral head epiphysis as a cause of cam impingement. Clin Orthop Relat Res 418:54–60PubMedCrossRef
56.
Zurück zum Zitat Thomee R, Jonasson P, Thorborg K, Sansone M, Ahlden M, Thomee C, Karlsson J, Baranto A (2014) Cross-cultural adaptation to Swedish and validation of the Copenhagen Hip and Groin Outcome Score (HAGOS) for pain, symptoms and physical function in patients with hip and groin disability due to femoro-acetabular impingement. Knee Surg Sports Traumatol Arthrosc 22:835–842PubMedCrossRef Thomee R, Jonasson P, Thorborg K, Sansone M, Ahlden M, Thomee C, Karlsson J, Baranto A (2014) Cross-cultural adaptation to Swedish and validation of the Copenhagen Hip and Groin Outcome Score (HAGOS) for pain, symptoms and physical function in patients with hip and groin disability due to femoro-acetabular impingement. Knee Surg Sports Traumatol Arthrosc 22:835–842PubMedCrossRef
57.
Zurück zum Zitat Thorborg K, Holmich P, Christensen R, Petersen J, Roos EM (2011) The Copenhagen Hip and Groin Outcome Score (HAGOS): development and validation according to the COSMIN checklist. Br J Sports Med 45:478–491PubMedCrossRef Thorborg K, Holmich P, Christensen R, Petersen J, Roos EM (2011) The Copenhagen Hip and Groin Outcome Score (HAGOS): development and validation according to the COSMIN checklist. Br J Sports Med 45:478–491PubMedCrossRef
58.
Zurück zum Zitat Tran P, Pritchard M, O’Donnell J (2013) Outcome of arthroscopic treatment for cam type femoroacetabular impingement in adolescents. ANZ J Surg 83:382–386PubMedCrossRef Tran P, Pritchard M, O’Donnell J (2013) Outcome of arthroscopic treatment for cam type femoroacetabular impingement in adolescents. ANZ J Surg 83:382–386PubMedCrossRef
59.
Zurück zum Zitat Tveit M, Rosengren BE, Nilsson JA, Karlsson MK (2012) Former male elite athletes have a higher prevalence of osteoarthritis and arthroplasty in the hip and knee than expected. Am J Sports Med 40:527–533PubMedCrossRef Tveit M, Rosengren BE, Nilsson JA, Karlsson MK (2012) Former male elite athletes have a higher prevalence of osteoarthritis and arthroplasty in the hip and knee than expected. Am J Sports Med 40:527–533PubMedCrossRef
60.
Zurück zum Zitat Van Thiel GS, Harris JD, Kang RW, Chahal J, Della Valle CJ, Bush-Joseph CA, Nho SJ (2013) Age-related differences in radiographic parameters for femoroacetabular impingement in hip arthroplasty patients. Arthroscopy 29:1182–1187PubMedCrossRef Van Thiel GS, Harris JD, Kang RW, Chahal J, Della Valle CJ, Bush-Joseph CA, Nho SJ (2013) Age-related differences in radiographic parameters for femoroacetabular impingement in hip arthroplasty patients. Arthroscopy 29:1182–1187PubMedCrossRef
61.
Zurück zum Zitat Watne LO, Torbergsen AC, Conroy S, Engedal K, Frihagen F, Hjorthaug GA, Juliebo V, Raeder J, Saltvedt I, Skovlund E, Wyller TB (2014) The effect of a pre- and postoperative orthogeriatric service on cognitive function in patients with hip fracture: randomized controlled trial (Oslo Orthogeriatric Trial). BMC Med 12:63-7015-12-63 Watne LO, Torbergsen AC, Conroy S, Engedal K, Frihagen F, Hjorthaug GA, Juliebo V, Raeder J, Saltvedt I, Skovlund E, Wyller TB (2014) The effect of a pre- and postoperative orthogeriatric service on cognitive function in patients with hip fracture: randomized controlled trial (Oslo Orthogeriatric Trial). BMC Med 12:63-7015-12-63
62.
Zurück zum Zitat Weir A, de Vos RJ, Moen M, Holmich P, Tol JL (2011) Prevalence of radiological signs of femoroacetabular impingement in patients presenting with long-standing adductor-related groin pain. Br J Sports Med 45:6–9PubMedCrossRef Weir A, de Vos RJ, Moen M, Holmich P, Tol JL (2011) Prevalence of radiological signs of femoroacetabular impingement in patients presenting with long-standing adductor-related groin pain. Br J Sports Med 45:6–9PubMedCrossRef
63.
Zurück zum Zitat Wenger DE, Kendell KR, Miner MR, Trousdale RT (2004) Acetabular labral tears rarely occur in the absence of bony abnormalities. Clin Orthop Relat Res 426:145–150PubMedCrossRef Wenger DE, Kendell KR, Miner MR, Trousdale RT (2004) Acetabular labral tears rarely occur in the absence of bony abnormalities. Clin Orthop Relat Res 426:145–150PubMedCrossRef
64.
Zurück zum Zitat Zilkens C, Miese F, Jager M, Bittersohl B, Krauspe R (2011) Magnetic resonance imaging of hip joint cartilage and labrum. Orthop Rev (Pavia) 3:e9CrossRef Zilkens C, Miese F, Jager M, Bittersohl B, Krauspe R (2011) Magnetic resonance imaging of hip joint cartilage and labrum. Orthop Rev (Pavia) 3:e9CrossRef
Metadaten
Titel
Femoro-acetabular impingement clinical research: is a composite outcome the answer?
verfasst von
Olufemi R. Ayeni
Mikael Sansone
Darren de Sa
Nicole Simunovic
Asheesh Bedi
Bryan T. Kelly
Forough Farrokhyar
Jon Karlsson
Publikationsdatum
01.01.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
Knee Surgery, Sports Traumatology, Arthroscopy / Ausgabe 1/2016
Print ISSN: 0942-2056
Elektronische ISSN: 1433-7347
DOI
https://doi.org/10.1007/s00167-014-3500-9

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