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Erschienen in: European Journal of Pediatrics 10/2009

01.10.2009 | Original Paper

Tetracycline-resistant Escherichia coli strains are inherited from parents and persist in the infant’s intestines in the absence of selective pressure

verfasst von: Martina Prelog, Katharina Grif, Cornelia Decristoforo, Reinhard Würzner, Ursula Kiechl-Kohlendorfer, Andrea Brunner, Lothar Bernd Zimmerhackl, Dorothea Orth

Erschienen in: European Journal of Pediatrics | Ausgabe 10/2009

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Abstract

The study investigated tetracycline (TC), ampicillin (AMP), cefazolin (CEF), and trimethoprim (TMP) resistance in Escherichia coli (E. coli) in the feces of 21 infants up to 6 months of age and in their parents in the absence of selective antimicrobial pressure. Clonality of strains was assessed by pulsed-field gel electrophoresis. Three infants had resistant E. coli strains in their feces identical to the mothers’ from week 1 on, which persisted over weeks. From week 2 on, in another four infants, persisting resistant E. coli were found, two of them identical to the mothers’. All of these persisting E. coli strains (except one family) showed at least resistance to TC. In infants, resistant E. coli strains inherited from their mothers tended to persist over months. Therefore, the persistence of resistant E. coli and their possible capacity to cause symptomatic infection or transfer its resistance genes to other bacteria deserves more attention.
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Metadaten
Titel
Tetracycline-resistant Escherichia coli strains are inherited from parents and persist in the infant’s intestines in the absence of selective pressure
verfasst von
Martina Prelog
Katharina Grif
Cornelia Decristoforo
Reinhard Würzner
Ursula Kiechl-Kohlendorfer
Andrea Brunner
Lothar Bernd Zimmerhackl
Dorothea Orth
Publikationsdatum
01.10.2009
Verlag
Springer-Verlag
Erschienen in
European Journal of Pediatrics / Ausgabe 10/2009
Print ISSN: 0340-6199
Elektronische ISSN: 1432-1076
DOI
https://doi.org/10.1007/s00431-008-0901-0

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