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Erschienen in:

04.05.2018 | Review

Development of minimum standards of care for juvenile localized scleroderma

verfasst von: Tamás Constantin, Ivan Foeldvari, Clare E. Pain, Annamária Pálinkás, Peter Höger, Monika Moll, Dana Nemkova, Lisa Weibel, Melinda Laczkovszki, Philip Clements, Kathryn S. Torok

Erschienen in: European Journal of Pediatrics | Ausgabe 7/2018

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Abstract

Juvenile localized scleroderma (jLS), also known as morphea, is an orphan disease. Pediatric guidelines regarding diagnosis, assessment, and management are lacking.

Our objective was to develop minimum standards of care for diagnosis, assessment, and management of jLS. A systematic review was undertaken to establish the pediatric evidence for assessment and monitoring of jLS. An expert panel, including members of the Pediatric Rheumatology European Society (PRES) Scleroderma Working Group, were invited to a consensus meeting where recommendations were developed based on evidence graded by the systematic review and, where evidence was lacking, consensus opinion. A nominal technique was used where 75% consensus was taken as agreement. Recommendations for diagnosis, assessment, and management were developed. Due to a lack of pediatric evidence, these were primarily consensus driven. Careful assessment for extra-cutaneous manifestations including synovitis, brain involvement, and uveitis were key features together with joint assessments between Dermatology and Rheumatology to improve and standardize care.

Conclusion: Management of jLS is varied. These recommendations should help provide standardization of assessment and care for those with this rare and potentially debilitating condition.

What is Known:
• Children with juvenile localized scleroderma (jLS) are managed by a number of specialties including pediatric rheumatologists and dermatologists, sometimes in shared clinics. Studies have shown that management varies considerably and that there are notable differences between specialties [1].
• There is very little published guidance on management of jLS.
What is new:
• These recommendations aim to standardize diagnosis, assessment, and management through review of pediatric evidence and consensus agreement.
• Joint review of patients by both pediatric rheumatologists and dermatologists is recommended.

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Titel: Development of minimum standards of care for juvenile localized scleroderma
verfasst von: Tamás Constantin
Ivan Foeldvari
Clare E. Pain
Annamária Pálinkás
Peter Höger
Monika Moll
Dana Nemkova
Lisa Weibel
Melinda Laczkovszki
Philip Clements
Kathryn S. Torok
Publikationsdatum: 04.05.2018
Verlag: Springer Berlin Heidelberg
Erschienen in: European Journal of Pediatrics / Ausgabe 7/2018
Print ISSN: 0340-6199
Elektronische ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-018-3144-8

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Development of minimum standards of care for juvenile localized scleroderma

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