Skip to main content
Erschienen in: Surgical Endoscopy 8/2018

29.01.2018

A single surgeon’s experience transitioning to robotic-assisted right colectomy with intracorporeal anastomosis

verfasst von: Alexandra C. W. Reitz, Ed Lin, Seth A. Rosen

Erschienen in: Surgical Endoscopy | Ausgabe 8/2018

Einloggen, um Zugang zu erhalten

Abstract

Background

Despite substantial evidence demonstrating benefits of minimally invasive surgery, a large percentage of right colectomies are still performed via an open technique. Most laparoscopic right colectomies are completed as a hybrid procedure with extracorporeal anastomosis. As part of a pure minimally invasive procedure, intracorporeal anastomosis (ICA) may confer additional benefits for patients. The robotic platform may shorten the learning curve for minimally invasive right colectomy with ICA.

Methods

From January 2014 to May 2016, 49 patients underwent robotic-assisted right colectomy by a board-certified colorectal surgeon (S.R). Extracorporeal anastomosis (ECA) was used in the first 20 procedures, whereas ICA was used in all subsequent procedures. Outcomes recorded in a database for retrospective review included operating time (OT), estimated blood loss (EBL), length of stay (LOS), conversion rate, complications, readmissions, and mortality rate.

Results

Comparison of average OT, EBL, and LOS between extracorporeal and intracorporeal groups demonstrated no significant differences. For all patients, average OT was 141.6 ± 25.8 (range 86–192) min, average EBL was 59.5 ± 83.3 (range 0–500) mL, and average LOS was 3.4 ± 1.19 (range 1.5–8) days. Four patients required conversion, all of which occurred in the extracorporeal group. There were no conversions after the 18th procedure. The 60-day mortality rate was 0%. There were no anastomotic leaks, ostomies created, or readmissions. As the surgeon gained experience, a statistically significant increase in lymph node sampling was observed in oncologic cases (p = .02).

Conclusions

The robotic platform may help more surgeons safely and efficiently transition to a purely minimally invasive procedure, enabling more patients to reap the benefits of less invasive surgery. Transitioning from ECA to ICA during robotic right colectomy resulted in no significant change in OT or LOS. A lower rate of conversion to open surgery was noted with increased experience.
Literatur
1.
Zurück zum Zitat Yeo HL, Isaacs AJ, Abelson JS, Milsom JW, Sedrakyan A (2016) Comparison of open, laparoscopic, and robotic colectomies using a large national database: outcomes and trends related to surgery center volume. Dis Colon Rectum 59(6):535–542CrossRefPubMed Yeo HL, Isaacs AJ, Abelson JS, Milsom JW, Sedrakyan A (2016) Comparison of open, laparoscopic, and robotic colectomies using a large national database: outcomes and trends related to surgery center volume. Dis Colon Rectum 59(6):535–542CrossRefPubMed
3.
Zurück zum Zitat van Oostendorp S, Elfrink A, Borstlap W, Schoonmade L, Sietses C, Meijerink J et al (2017) Intracorporeal versus extracorporeal anastomosis in right hemicolectomy: a systematic review and meta-analysis. Surg Endosc 31(1):64–77CrossRefPubMed van Oostendorp S, Elfrink A, Borstlap W, Schoonmade L, Sietses C, Meijerink J et al (2017) Intracorporeal versus extracorporeal anastomosis in right hemicolectomy: a systematic review and meta-analysis. Surg Endosc 31(1):64–77CrossRefPubMed
4.
Zurück zum Zitat Lujan HJ, Maciel VH, Romero R, Plasencia G (2013) Laparoscopic versus robotic right colectomy: a single surgeon’s experience. J Robot Surg 7(2):95–102CrossRefPubMed Lujan HJ, Maciel VH, Romero R, Plasencia G (2013) Laparoscopic versus robotic right colectomy: a single surgeon’s experience. J Robot Surg 7(2):95–102CrossRefPubMed
5.
Zurück zum Zitat Jamali FR, Soweid AM, Dimassi H, Bailey C, Leroy J, Marescaux J (2008) Evaluating the degree of difficulty of laparoscopic colorectal surgery. Arch Surg 143(8):762–767CrossRefPubMed Jamali FR, Soweid AM, Dimassi H, Bailey C, Leroy J, Marescaux J (2008) Evaluating the degree of difficulty of laparoscopic colorectal surgery. Arch Surg 143(8):762–767CrossRefPubMed
6.
Zurück zum Zitat Trastulli S, Desiderio J, Farinacci F, Ricci F, Listorti C, Cirocchi R et al (2013) Robotic right colectomy for cancer with intracorporeal anastomosis: short-term outcomes from a single institution. Int J Colorectal Dis 28(6):807–814CrossRefPubMed Trastulli S, Desiderio J, Farinacci F, Ricci F, Listorti C, Cirocchi R et al (2013) Robotic right colectomy for cancer with intracorporeal anastomosis: short-term outcomes from a single institution. Int J Colorectal Dis 28(6):807–814CrossRefPubMed
7.
Zurück zum Zitat Miller PE, Dao H, Paluvoi N, Bailey M, Margolin D, Shah N et al (2016) Comparison of 30-day postoperative outcomes after laparoscopic vs robotic colectomy. J Am Coll Surg 223(2):369–373CrossRefPubMed Miller PE, Dao H, Paluvoi N, Bailey M, Margolin D, Shah N et al (2016) Comparison of 30-day postoperative outcomes after laparoscopic vs robotic colectomy. J Am Coll Surg 223(2):369–373CrossRefPubMed
8.
Zurück zum Zitat Wu Q, Jin C, Hu T, Wei M, Wang Z (2017) Intracorporeal versus extracorporeal anastomosis in laparoscopic right colectomy: a systematic review and meta-analysis. J Laparoendosc Adv Surg Tech A 27(4):348–357CrossRefPubMed Wu Q, Jin C, Hu T, Wei M, Wang Z (2017) Intracorporeal versus extracorporeal anastomosis in laparoscopic right colectomy: a systematic review and meta-analysis. J Laparoendosc Adv Surg Tech A 27(4):348–357CrossRefPubMed
9.
Zurück zum Zitat Fabozzi M, Allieta R, Brachet Contul R, Grivon M, Millo P, Lale-Murix E et al (2010) Comparison of short- and medium-term results between laparoscopically assisted and totally laparoscopic right hemicolectomy: a case-control study. Surg Endosc 24(9):2085–2091CrossRefPubMed Fabozzi M, Allieta R, Brachet Contul R, Grivon M, Millo P, Lale-Murix E et al (2010) Comparison of short- and medium-term results between laparoscopically assisted and totally laparoscopic right hemicolectomy: a case-control study. Surg Endosc 24(9):2085–2091CrossRefPubMed
10.
Zurück zum Zitat Fabozzi M, Cirillo P, Corcione F (2016) Surgical approach to right colon cancer: from open technique to robot. State of art. World J Gastrointest Surg 8(8):564–573CrossRefPubMedPubMedCentral Fabozzi M, Cirillo P, Corcione F (2016) Surgical approach to right colon cancer: from open technique to robot. State of art. World J Gastrointest Surg 8(8):564–573CrossRefPubMedPubMedCentral
11.
Zurück zum Zitat Guerrieri M, Campagnacci R, Sperti P, Belfiori G, Gesuita R, Ghiselli R (2015) Totally robotic vs 3D laparoscopic colectomy: a single centers preliminary experience. World J Gastroenterol 21(46):13152–13159CrossRefPubMedPubMedCentral Guerrieri M, Campagnacci R, Sperti P, Belfiori G, Gesuita R, Ghiselli R (2015) Totally robotic vs 3D laparoscopic colectomy: a single centers preliminary experience. World J Gastroenterol 21(46):13152–13159CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Formisano G, Misitano P, Giuliani G, Calamati G, Salvischiani L, Bianchi PP (2016) Laparoscopic versus robotic right colectomy: technique and outcomes. Updates Surg 68(1):63–69CrossRefPubMed Formisano G, Misitano P, Giuliani G, Calamati G, Salvischiani L, Bianchi PP (2016) Laparoscopic versus robotic right colectomy: technique and outcomes. Updates Surg 68(1):63–69CrossRefPubMed
13.
Zurück zum Zitat Park JS, Choi GS, Park SY, Kim HJ, Ryuk JP (2012) Randomized clinical trial of robot-assisted versus standard laparoscopic right colectomy. Br J Surg 99(9):1219–1226CrossRefPubMed Park JS, Choi GS, Park SY, Kim HJ, Ryuk JP (2012) Randomized clinical trial of robot-assisted versus standard laparoscopic right colectomy. Br J Surg 99(9):1219–1226CrossRefPubMed
14.
Zurück zum Zitat Rondelli F, Balzarotti R, Villa F, Guerra A, Avenia N, Mariani E et al (2015) Is robot-assisted laparoscopic right colectomy more effective than the conventional laparoscopic procedure? A meta-analysis of short-term outcomes. Int J Surg 18:75–82CrossRefPubMed Rondelli F, Balzarotti R, Villa F, Guerra A, Avenia N, Mariani E et al (2015) Is robot-assisted laparoscopic right colectomy more effective than the conventional laparoscopic procedure? A meta-analysis of short-term outcomes. Int J Surg 18:75–82CrossRefPubMed
15.
Zurück zum Zitat de’Angelis N, Lizzi V, Azoulay D, Brunetti F (2016) Robotic Versus laparoscopic right colectomy for colon cancer: analysis of the initial simultaneous learning curve of a surgical fellow. J Laparoendosc Adv Surg Tech A 26(11):882–892CrossRefPubMed de’Angelis N, Lizzi V, Azoulay D, Brunetti F (2016) Robotic Versus laparoscopic right colectomy for colon cancer: analysis of the initial simultaneous learning curve of a surgical fellow. J Laparoendosc Adv Surg Tech A 26(11):882–892CrossRefPubMed
16.
Zurück zum Zitat Antoniou SA, Antoniou GA, Koch OO, Pointner R, Granderath FA (2012) Robot-assisted laparoscopic surgery of the colon and rectum. Surg Endosc 26(1):1–11CrossRefPubMed Antoniou SA, Antoniou GA, Koch OO, Pointner R, Granderath FA (2012) Robot-assisted laparoscopic surgery of the colon and rectum. Surg Endosc 26(1):1–11CrossRefPubMed
17.
Zurück zum Zitat Morpurgo E, Contardo T, Molaro R, Zerbinati A, Orsini C, D’Annibale A (2013) Robotic-assisted intracorporeal anastomosis versus extracorporeal anastomosis in laparoscopic right hemicolectomy for cancer: a case control study. J Laparoendosc Adv Surg Tech A 23(5):414–417CrossRefPubMed Morpurgo E, Contardo T, Molaro R, Zerbinati A, Orsini C, D’Annibale A (2013) Robotic-assisted intracorporeal anastomosis versus extracorporeal anastomosis in laparoscopic right hemicolectomy for cancer: a case control study. J Laparoendosc Adv Surg Tech A 23(5):414–417CrossRefPubMed
18.
Zurück zum Zitat Franklin ME Jr, Gonzalez JJ Jr, Miter DB, Mansur JH, Trevino JM, Glass JL et al (2004) Laparoscopic right hemicolectomy for cancer: 11-year experience. Rev Gastroenterol Mex 69(Suppl 1):65–72PubMed Franklin ME Jr, Gonzalez JJ Jr, Miter DB, Mansur JH, Trevino JM, Glass JL et al (2004) Laparoscopic right hemicolectomy for cancer: 11-year experience. Rev Gastroenterol Mex 69(Suppl 1):65–72PubMed
19.
Zurück zum Zitat Rawlings AL, Woodland JH, Vegunta RK, Crawford DL (2007) Robotic versus laparoscopic colectomy. Surg Endosc 21(10):1701–1708CrossRefPubMed Rawlings AL, Woodland JH, Vegunta RK, Crawford DL (2007) Robotic versus laparoscopic colectomy. Surg Endosc 21(10):1701–1708CrossRefPubMed
20.
Zurück zum Zitat Lacy AM, Garcia-Valdecasas JC, Delgado S, Castells A, Taura P, Pique JM et al (2002) Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet 359(9325):2224–2229CrossRefPubMed Lacy AM, Garcia-Valdecasas JC, Delgado S, Castells A, Taura P, Pique JM et al (2002) Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial. Lancet 359(9325):2224–2229CrossRefPubMed
21.
Zurück zum Zitat Lujan HJ, Molano A, Burgos A, Rivera B, Plasencia G (2015) Robotic right colectomy with intracorporeal anastomosis: experience with 52 consecutive cases. J Laparoendosc Adv Surg Tech A 25(2):117–122CrossRefPubMed Lujan HJ, Molano A, Burgos A, Rivera B, Plasencia G (2015) Robotic right colectomy with intracorporeal anastomosis: experience with 52 consecutive cases. J Laparoendosc Adv Surg Tech A 25(2):117–122CrossRefPubMed
22.
Zurück zum Zitat Deutsch GB, Sathyanarayana SA, Gunabushanam V, Mishra N, Rubach E, Zemon H et al (2012) Robotic vs. laparoscopic colorectal surgery: an institutional experience. Surg Endosc 26(4):956–963CrossRefPubMed Deutsch GB, Sathyanarayana SA, Gunabushanam V, Mishra N, Rubach E, Zemon H et al (2012) Robotic vs. laparoscopic colorectal surgery: an institutional experience. Surg Endosc 26(4):956–963CrossRefPubMed
23.
Zurück zum Zitat Petrucciani N, Sirimarco D, Nigri GR, Magistri P, La Torre M, Aurello P et al (2015) Robotic right colectomy: a worthwhile procedure? Results of a meta-analysis of trials comparing robotic versus laparoscopic right colectomy. J Minim Access Surg 11(1):22–28CrossRefPubMedPubMedCentral Petrucciani N, Sirimarco D, Nigri GR, Magistri P, La Torre M, Aurello P et al (2015) Robotic right colectomy: a worthwhile procedure? Results of a meta-analysis of trials comparing robotic versus laparoscopic right colectomy. J Minim Access Surg 11(1):22–28CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Barrie J, Jayne DG, Wright J, Murray CJ, Collinson FJ, Pavitt SH (2014) Attaining surgical competency and its implications in surgical clinical trial design: a systematic review of the learning curve in laparoscopic and robot-assisted laparoscopic colorectal cancer surgery. Ann Surg Oncol 21(3):829–840CrossRefPubMed Barrie J, Jayne DG, Wright J, Murray CJ, Collinson FJ, Pavitt SH (2014) Attaining surgical competency and its implications in surgical clinical trial design: a systematic review of the learning curve in laparoscopic and robot-assisted laparoscopic colorectal cancer surgery. Ann Surg Oncol 21(3):829–840CrossRefPubMed
25.
Zurück zum Zitat Bokhari MB, Patel CB, Ramos-Valadez DI, Ragupathi M, Haas EM (2011) Learning curve for robotic-assisted laparoscopic colorectal surgery. Surg Endosc 25(3):855–860CrossRefPubMed Bokhari MB, Patel CB, Ramos-Valadez DI, Ragupathi M, Haas EM (2011) Learning curve for robotic-assisted laparoscopic colorectal surgery. Surg Endosc 25(3):855–860CrossRefPubMed
26.
Zurück zum Zitat Singh R, Omiccioli A, Hegge S, McKinley C (2008) Does the extraction-site location in laparoscopic colorectal surgery have an impact on incisional hernia rates? Surg Endosc 22(12):2596–2600CrossRefPubMed Singh R, Omiccioli A, Hegge S, McKinley C (2008) Does the extraction-site location in laparoscopic colorectal surgery have an impact on incisional hernia rates? Surg Endosc 22(12):2596–2600CrossRefPubMed
27.
Zurück zum Zitat D’Annibale A, Pernazza G, Morpurgo E, Monsellato I, Pende V, Lucandri G et al (2012) Robotic right colon resection: evaluation of first 50 consecutive cases for malignant disease. Indian J Surg Oncol 3(4):279–285CrossRefPubMedPubMedCentral D’Annibale A, Pernazza G, Morpurgo E, Monsellato I, Pende V, Lucandri G et al (2012) Robotic right colon resection: evaluation of first 50 consecutive cases for malignant disease. Indian J Surg Oncol 3(4):279–285CrossRefPubMedPubMedCentral
28.
Zurück zum Zitat Samia H, Lawrence J, Nobel T, Stein S, Champagne BJ, Delaney CP (2013) Extraction site location and incisional hernias after laparoscopic colorectal surgery: should we be avoiding the midline? Am J Surg 205(3):264–267 (discussion 8)CrossRefPubMed Samia H, Lawrence J, Nobel T, Stein S, Champagne BJ, Delaney CP (2013) Extraction site location and incisional hernias after laparoscopic colorectal surgery: should we be avoiding the midline? Am J Surg 205(3):264–267 (discussion 8)CrossRefPubMed
29.
Zurück zum Zitat Shapiro R, Keler U, Segev L, Sarna S, Hatib K, Hazzan D (2016) Laparoscopic right hemicolectomy with intracorporeal anastomosis: short- and long-term benefits in comparison with extracorporeal anastomosis. Surg Endosc 30(9):3823–3829CrossRefPubMed Shapiro R, Keler U, Segev L, Sarna S, Hatib K, Hazzan D (2016) Laparoscopic right hemicolectomy with intracorporeal anastomosis: short- and long-term benefits in comparison with extracorporeal anastomosis. Surg Endosc 30(9):3823–3829CrossRefPubMed
30.
Zurück zum Zitat van Oostendorp S, Elfrink A, Borstlap W, Schoonmade L, Sietses C, Meijerink J et al. (2017) Intracorporeal versus extracorporeal anastomosis in right hemicolectomy: a systematic review and meta-analysis. Surg Endosc 31:64–77CrossRefPubMed van Oostendorp S, Elfrink A, Borstlap W, Schoonmade L, Sietses C, Meijerink J et al. (2017) Intracorporeal versus extracorporeal anastomosis in right hemicolectomy: a systematic review and meta-analysis. Surg Endosc 31:64–77CrossRefPubMed
31.
Zurück zum Zitat Vignali A, Bissolati M, De Nardi P, Di Palo S, Staudacher C (2016) Extracorporeal vs. intracorporeal ileocolic stapled anastomoses in laparoscopic right colectomy: an interim analysis of a randomized clinical trial. J Laparoendosc Adv Surg Tech A 26(5):343–348CrossRefPubMed Vignali A, Bissolati M, De Nardi P, Di Palo S, Staudacher C (2016) Extracorporeal vs. intracorporeal ileocolic stapled anastomoses in laparoscopic right colectomy: an interim analysis of a randomized clinical trial. J Laparoendosc Adv Surg Tech A 26(5):343–348CrossRefPubMed
32.
Zurück zum Zitat Bergamaschi R, Schochet E, Haughn C, Burke M, Reed JF 3rd, Arnaud JP (2008) Standardized laparoscopic intracorporeal right colectomy for cancer: short-term outcome in 111 unselected patients. Dis Colon Rectum 51(9):1350–1355CrossRefPubMed Bergamaschi R, Schochet E, Haughn C, Burke M, Reed JF 3rd, Arnaud JP (2008) Standardized laparoscopic intracorporeal right colectomy for cancer: short-term outcome in 111 unselected patients. Dis Colon Rectum 51(9):1350–1355CrossRefPubMed
33.
Zurück zum Zitat Greene FL, Page DL, Fleming ID, Fritz A, Balch CM, Haller DG et al (2002) American joint committee on cancer staging manual, 6th edn. Springer, New YorkCrossRef Greene FL, Page DL, Fleming ID, Fritz A, Balch CM, Haller DG et al (2002) American joint committee on cancer staging manual, 6th edn. Springer, New YorkCrossRef
34.
Zurück zum Zitat Feroci F, Lenzi E, Garzi A, Vannucchi A, Cantafio S, Scatizzi M (2013) Intracorporeal versus extracorporeal anastomosis after laparoscopic right hemicolectomy for cancer: a systematic review and meta-analysis. Int J Colorectal Dis 28(9):1177–1186CrossRefPubMed Feroci F, Lenzi E, Garzi A, Vannucchi A, Cantafio S, Scatizzi M (2013) Intracorporeal versus extracorporeal anastomosis after laparoscopic right hemicolectomy for cancer: a systematic review and meta-analysis. Int J Colorectal Dis 28(9):1177–1186CrossRefPubMed
Metadaten
Titel
A single surgeon’s experience transitioning to robotic-assisted right colectomy with intracorporeal anastomosis
verfasst von
Alexandra C. W. Reitz
Ed Lin
Seth A. Rosen
Publikationsdatum
29.01.2018
Verlag
Springer US
Erschienen in
Surgical Endoscopy / Ausgabe 8/2018
Print ISSN: 0930-2794
Elektronische ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-018-6074-7

Weitere Artikel der Ausgabe 8/2018

Surgical Endoscopy 8/2018 Zur Ausgabe

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Was nützt die Kraniektomie bei schwerer tiefer Hirnblutung?

17.05.2024 Hirnblutung Nachrichten

Eine Studie zum Nutzen der druckentlastenden Kraniektomie nach schwerer tiefer supratentorieller Hirnblutung deutet einen Nutzen der Operation an. Für überlebende Patienten ist das dennoch nur eine bedingt gute Nachricht.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.