Skip to main content
Erschienen in: European Journal of Orthopaedic Surgery & Traumatology 3/2019

26.10.2018 | Original Article • ANKLE - GENERAL ORTHOPAEDICS

Mid-portion Achilles tendinopathy in runners with metabolic disorders

verfasst von: Michele Abate, Vincenzo Salini

Erschienen in: European Journal of Orthopaedic Surgery & Traumatology | Ausgabe 3/2019

Einloggen, um Zugang zu erhalten

Abstract

Introduction

Running is a very popular modality of physical activity, which may help to lose weight and normalize pathological values of blood parameters in subjects suffering from metabolic disorders. Given that both overuse and metabolic pathologies are responsible for the onset of tendon damage, aim of the present study was to evaluate whether the first group of pathogenetic factors or the latter was more responsible for mid-portion Achilles tendinopathy.

Method

Thirty-six and 28 subjects with and without mid-portion Achilles tendinopathy, who were regular runners and started running for metabolic disorders, were enrolled, respectively. Information about body weight and blood parameters at baseline was collected. The characteristics of running practice, dietary habits and anthropometric measures were registered. An ultrasound evaluation of the tendon was performed, and the blood metabolic parameters were evaluated.

Results

The amount of running years and mileage was equivalent in both groups. A similar weight loss was observed; the subjects with mid-portion Achilles tendinopathy showed a worse metabolic profile (Hb1aC%, p = 0.008; total cholesterol, p = 0.04; HDL cholesterol, p = 0.003; triglycerides, p = 0.009).

Conclusions

These findings suggest that the subjects with less evident positive effects of running on metabolism are more exposed to the onset of mid-portion Achilles tendinopathy.
Literatur
1.
Zurück zum Zitat Fiuza-Luces C, Garatachea N, Berger NA, Lucia A (2013) Exercise is the real polypill. Physiology 5:330–358CrossRef Fiuza-Luces C, Garatachea N, Berger NA, Lucia A (2013) Exercise is the real polypill. Physiology 5:330–358CrossRef
2.
Zurück zum Zitat Williams PT, Thompson PD (2013) Walking versus running for hypertension, cholesterol, and diabetes mellitus risk reduction. Arterioscler Thromb Vasc Biol 33:1085–1091CrossRefPubMedPubMedCentral Williams PT, Thompson PD (2013) Walking versus running for hypertension, cholesterol, and diabetes mellitus risk reduction. Arterioscler Thromb Vasc Biol 33:1085–1091CrossRefPubMedPubMedCentral
3.
Zurück zum Zitat Kluitenberg B, van Middelkoop M, Diercks R, van der Worp H (2015) What are the differences in injury proportions between different populations of runners? A systematic review and meta-analysis. Sports Med 45:1143–1161CrossRefPubMedPubMedCentral Kluitenberg B, van Middelkoop M, Diercks R, van der Worp H (2015) What are the differences in injury proportions between different populations of runners? A systematic review and meta-analysis. Sports Med 45:1143–1161CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Tschopp M, Brunner F (2017) Diseases and overuse injuries of the lower extremities in long distance runners. Z Rheumatol 76:443–450CrossRefPubMed Tschopp M, Brunner F (2017) Diseases and overuse injuries of the lower extremities in long distance runners. Z Rheumatol 76:443–450CrossRefPubMed
5.
Zurück zum Zitat Ribbans WJ, Collins M (2013) Pathology of the tendo Achillis: do our genes contribute? Bone Joint J 95-B:305–313CrossRefPubMed Ribbans WJ, Collins M (2013) Pathology of the tendo Achillis: do our genes contribute? Bone Joint J 95-B:305–313CrossRefPubMed
6.
Zurück zum Zitat Abate M, Schiavone C, Salini V, Andia I (2013) Occurrence of tendon pathologies in metabolic disorders. Rheumatology 52:599–608CrossRefPubMed Abate M, Schiavone C, Salini V, Andia I (2013) Occurrence of tendon pathologies in metabolic disorders. Rheumatology 52:599–608CrossRefPubMed
8.
Zurück zum Zitat Thompson FE, Midthune D, Kahle L, Dodd KW (2017) Development and evaluation of the National Cancer Institute’s dietary screener questionnaire scoring algorithms. J Nutr 147:1226–1233CrossRefPubMedPubMedCentral Thompson FE, Midthune D, Kahle L, Dodd KW (2017) Development and evaluation of the National Cancer Institute’s dietary screener questionnaire scoring algorithms. J Nutr 147:1226–1233CrossRefPubMedPubMedCentral
9.
Zurück zum Zitat Maffulli N, Longo UG, Testa V, Oliva F, Capasso G, Denaro V (2008) Italian translation of the VISA-A score for tendinopathy of the main body of the Achilles tendon. Disabil Rehabil 30:1635–1639CrossRefPubMed Maffulli N, Longo UG, Testa V, Oliva F, Capasso G, Denaro V (2008) Italian translation of the VISA-A score for tendinopathy of the main body of the Achilles tendon. Disabil Rehabil 30:1635–1639CrossRefPubMed
10.
Zurück zum Zitat Sunding K, Fahlström M, Werner S, Forssblad M, Willberg L (2016) Evaluation of Achilles and patellar tendinopathy with greyscale ultrasound and colour Doppler: using a four-grade scale. Knee Surg Sports Traumatol Arthrosc 24:1988–19896CrossRefPubMed Sunding K, Fahlström M, Werner S, Forssblad M, Willberg L (2016) Evaluation of Achilles and patellar tendinopathy with greyscale ultrasound and colour Doppler: using a four-grade scale. Knee Surg Sports Traumatol Arthrosc 24:1988–19896CrossRefPubMed
11.
Zurück zum Zitat Salini V, Abate M (2011) Percutaneous steroidal treatment in relapses of chronic tendinopathies: a pilot study. Int J Immunopathol Pharmacol 24:211–216CrossRefPubMed Salini V, Abate M (2011) Percutaneous steroidal treatment in relapses of chronic tendinopathies: a pilot study. Int J Immunopathol Pharmacol 24:211–216CrossRefPubMed
12.
Zurück zum Zitat Ohberg L, Lorentzon R, Alfredson H (2001) Neovascularisation in Achilles tendons with painful tendinosis but not in normal tendons: an ultrasonographic investigation. Knee Surg Sports Traumatol Arthrosc 9:233–238CrossRefPubMed Ohberg L, Lorentzon R, Alfredson H (2001) Neovascularisation in Achilles tendons with painful tendinosis but not in normal tendons: an ultrasonographic investigation. Knee Surg Sports Traumatol Arthrosc 9:233–238CrossRefPubMed
13.
Zurück zum Zitat Shaikh Z, Perry M, Morrissey D, Ahmad M, Del Buono A, Maffulli N (2012) Achilles tendinopathy in club runners. Int J Sports Med 33:390–394CrossRefPubMed Shaikh Z, Perry M, Morrissey D, Ahmad M, Del Buono A, Maffulli N (2012) Achilles tendinopathy in club runners. Int J Sports Med 33:390–394CrossRefPubMed
14.
Zurück zum Zitat van der Worp MP, ten Haaf DS, van Cingel R, de Wijer A, Nijhuis-van der Sanden MW, Staal JB (2015) Injuries in runners; a systematic review on risk factors and sex differences. PLoS ONE 10:e0114937CrossRefPubMedPubMedCentral van der Worp MP, ten Haaf DS, van Cingel R, de Wijer A, Nijhuis-van der Sanden MW, Staal JB (2015) Injuries in runners; a systematic review on risk factors and sex differences. PLoS ONE 10:e0114937CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Abate M, Salini V, Schiavone C (2016) Achilles tendinopathy in elderly subjects with type II diabetes: the role of sport activities. Aging Clin Exp Res 28:355–358CrossRefPubMed Abate M, Salini V, Schiavone C (2016) Achilles tendinopathy in elderly subjects with type II diabetes: the role of sport activities. Aging Clin Exp Res 28:355–358CrossRefPubMed
16.
Zurück zum Zitat Tilley BJ, Cook JL, Docking SI, Gaida JE (2015) Is higher serum cholesterol associated with altered tendon structure or tendon pain? A systematic review. Br J Sports Med 49:1504–1509CrossRefPubMedPubMedCentral Tilley BJ, Cook JL, Docking SI, Gaida JE (2015) Is higher serum cholesterol associated with altered tendon structure or tendon pain? A systematic review. Br J Sports Med 49:1504–1509CrossRefPubMedPubMedCentral
17.
18.
Zurück zum Zitat Pedersen BK (2017) Anti-inflammatory effects of exercise: role in diabetes and cardiovascular disease. Eur J Clin Investig 47:600–611CrossRef Pedersen BK (2017) Anti-inflammatory effects of exercise: role in diabetes and cardiovascular disease. Eur J Clin Investig 47:600–611CrossRef
19.
Zurück zum Zitat Neufer PD, Bamman MM, Muoio DM et al (2015) Understanding the cellular and molecular mechanisms of physical activity-induced health benefits. Cell Metab 22:4–11CrossRefPubMed Neufer PD, Bamman MM, Muoio DM et al (2015) Understanding the cellular and molecular mechanisms of physical activity-induced health benefits. Cell Metab 22:4–11CrossRefPubMed
20.
Zurück zum Zitat Bouchard C, Rankinen T (2001) Individual differences in response to regular physical activity. Med Sci Sports Exerc 33:S446–S451CrossRefPubMed Bouchard C, Rankinen T (2001) Individual differences in response to regular physical activity. Med Sci Sports Exerc 33:S446–S451CrossRefPubMed
21.
Zurück zum Zitat Kohrt WM, Malley MT, Coggan AR et al (1991) Effects of gender, age, and fitness level on response of VO2 max to training in 60–71 yr olds. J Appl Physiol 71:2004–2011CrossRefPubMed Kohrt WM, Malley MT, Coggan AR et al (1991) Effects of gender, age, and fitness level on response of VO2 max to training in 60–71 yr olds. J Appl Physiol 71:2004–2011CrossRefPubMed
22.
Zurück zum Zitat Lessard SJ, Rivas DA, Alves-Wagner AB et al (2013) Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks. Diabetes 62:2717–2727CrossRefPubMedPubMedCentral Lessard SJ, Rivas DA, Alves-Wagner AB et al (2013) Resistance to aerobic exercise training causes metabolic dysfunction and reveals novel exercise-regulated signaling networks. Diabetes 62:2717–2727CrossRefPubMedPubMedCentral
23.
Zurück zum Zitat Hay M, Patricios J, Collins R et al (2013) Association of type XI collagen genes with chronic Achilles tendinopathy in independent populations from South Africa and Australia. Br J Sports Med 47:569–574CrossRefPubMed Hay M, Patricios J, Collins R et al (2013) Association of type XI collagen genes with chronic Achilles tendinopathy in independent populations from South Africa and Australia. Br J Sports Med 47:569–574CrossRefPubMed
24.
Zurück zum Zitat Nell EM, Van Der Merwe L, Cook J, Handley CJ, Collins M, September AV (2012) The apoptosis pathway and the genetic predisposition to Achilles tendinopathy. J Orthop Res 30:1719–1724CrossRefPubMed Nell EM, Van Der Merwe L, Cook J, Handley CJ, Collins M, September AV (2012) The apoptosis pathway and the genetic predisposition to Achilles tendinopathy. J Orthop Res 30:1719–1724CrossRefPubMed
25.
Zurück zum Zitat Mansfield JC, Holden H, Tarlow JK et al (1994) Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist. Gastroenterology 106:637CrossRefPubMed Mansfield JC, Holden H, Tarlow JK et al (1994) Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonist. Gastroenterology 106:637CrossRefPubMed
26.
Zurück zum Zitat Langdahl BL, Løkke E, Carstens M, Stenkjær LL, Eriksen EF (2000) Osteoporotic fractures are associated with an 86-base pair repeat polymorphism in the interleukin-1-receptor antagonist gene but not with polymorphisms in the interleukin-1β gene. J Bone Miner Res 15:402–414CrossRefPubMed Langdahl BL, Løkke E, Carstens M, Stenkjær LL, Eriksen EF (2000) Osteoporotic fractures are associated with an 86-base pair repeat polymorphism in the interleukin-1-receptor antagonist gene but not with polymorphisms in the interleukin-1β gene. J Bone Miner Res 15:402–414CrossRefPubMed
27.
Zurück zum Zitat Olofsson PS, Sheikine Y, Jatta K et al (2009) A functional interleukin-1 receptor antagonist polymorphism influences atherosclerosis development. The interleukin-1 beta: interleukin-1 receptor antagonist balance in atherosclerosis. Circ J 73:1531–1536CrossRefPubMed Olofsson PS, Sheikine Y, Jatta K et al (2009) A functional interleukin-1 receptor antagonist polymorphism influences atherosclerosis development. The interleukin-1 beta: interleukin-1 receptor antagonist balance in atherosclerosis. Circ J 73:1531–1536CrossRefPubMed
28.
Zurück zum Zitat Everard W, Thornton S, Scott E (1995) Motivation in the committed runner: correlations between self-report scales and behavior. Health Promot Int 10(3):177–184CrossRef Everard W, Thornton S, Scott E (1995) Motivation in the committed runner: correlations between self-report scales and behavior. Health Promot Int 10(3):177–184CrossRef
29.
Zurück zum Zitat Short ME, Goetzel RZ, Tabrizi MJ, Ozminkowski RJ, Gibson TB, DeJoy DM, Wilson MG (2009) How accurate are self-reports? An analysis of self-reported healthcare utilization and absence when compared to administrative data. J Occup Environ Med 51:786–796CrossRefPubMedPubMedCentral Short ME, Goetzel RZ, Tabrizi MJ, Ozminkowski RJ, Gibson TB, DeJoy DM, Wilson MG (2009) How accurate are self-reports? An analysis of self-reported healthcare utilization and absence when compared to administrative data. J Occup Environ Med 51:786–796CrossRefPubMedPubMedCentral
30.
Zurück zum Zitat Colditz G, Martin AP, Stampfer MJ, Willett WC, Sampson L, Rosner B, Hennekens CH, Speizer FE (1986) Validation of questionnaire information on risk factors and disease outcomes in a prospective cohort study of women. Am J Epidemiol 123:894–900CrossRef Colditz G, Martin AP, Stampfer MJ, Willett WC, Sampson L, Rosner B, Hennekens CH, Speizer FE (1986) Validation of questionnaire information on risk factors and disease outcomes in a prospective cohort study of women. Am J Epidemiol 123:894–900CrossRef
Metadaten
Titel
Mid-portion Achilles tendinopathy in runners with metabolic disorders
verfasst von
Michele Abate
Vincenzo Salini
Publikationsdatum
26.10.2018
Verlag
Springer Paris
Erschienen in
European Journal of Orthopaedic Surgery & Traumatology / Ausgabe 3/2019
Print ISSN: 1633-8065
Elektronische ISSN: 1432-1068
DOI
https://doi.org/10.1007/s00590-018-2336-2

Weitere Artikel der Ausgabe 3/2019

European Journal of Orthopaedic Surgery & Traumatology 3/2019 Zur Ausgabe

Original Article • SHOULDER - ARTHROPLASTY

Predetermining glenoid dimensions using the scapular dimensions

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Knie-TEP: Kein Vorteil durch antibiotikahaltigen Knochenzement

29.05.2024 Periprothetische Infektionen Nachrichten

Zur Zementierung einer Knie-TEP wird in Deutschland zu über 98% Knochenzement verwendet, der mit einem Antibiotikum beladen ist. Ob er wirklich besser ist als Zement ohne Antibiotikum, kann laut Registerdaten bezweifelt werden.

Häusliche Gewalt in der orthopädischen Notaufnahme oft nicht erkannt

28.05.2024 Häusliche Gewalt Nachrichten

In der Notaufnahme wird die Chance, Opfer von häuslicher Gewalt zu identifizieren, von Orthopäden und Orthopädinnen offenbar zu wenig genutzt. Darauf deuten die Ergebnisse einer Fragebogenstudie an der Sahlgrenska-Universität in Schweden hin.

Fehlerkultur in der Medizin – Offenheit zählt!

28.05.2024 Fehlerkultur Podcast

Darüber reden und aus Fehlern lernen, sollte das Motto in der Medizin lauten. Und zwar nicht nur im Sinne der Patientensicherheit. Eine negative Fehlerkultur kann auch die Behandelnden ernsthaft krank machen, warnt Prof. Dr. Reinhard Strametz. Ein Plädoyer und ein Leitfaden für den offenen Umgang mit kritischen Ereignissen in Medizin und Pflege.

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.