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Erschienen in: Journal of Neural Transmission 4/2013

01.04.2013 | Neurology and Preclinical Neurological Studies - Review Article

The epidemiology of pain in Parkinson’s disease

verfasst von: Giovanni Defazio, Angelo Gigante, Paola Mancino, Michele Tinazzi

Erschienen in: Journal of Neural Transmission | Ausgabe 4/2013

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Abstract

Pain occurring in Parkinson’s disease (PD) may affect a large proportion of patients. Based on the results of the methodologically more robust case–control studies that detected a significantly greater frequency of pain in PD patients than in control subjects, pain should now be considered as a non-motor symptom of PD. The heterogeneous quality of pain, the variable relationship of pain with parkinsonian motor signs, and the mixed response of pain to dopaminergic drugs suggest complex mechanisms for pain in PD. Some evidence raises the possibility of common mechanisms shared by pain patients, regardless of the clinical heterogeneity of pain and its variable relationship with motor signs.
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Metadaten
Titel
The epidemiology of pain in Parkinson’s disease
verfasst von
Giovanni Defazio
Angelo Gigante
Paola Mancino
Michele Tinazzi
Publikationsdatum
01.04.2013
Verlag
Springer Vienna
Erschienen in
Journal of Neural Transmission / Ausgabe 4/2013
Print ISSN: 0300-9564
Elektronische ISSN: 1435-1463
DOI
https://doi.org/10.1007/s00702-012-0915-7

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