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19.10.2021 | COVID-19 | COVID-19 Zur Zeit gratis

The case of encephalitis in a COVID-19 pediatric patient

verfasst von: Lidia Urso, Maria Grazia Distefano, Gaetano Cambula, Angela Irene Colomba, Domenico Nuzzo, Pasquale Picone, Daniela Giacomazza, Luigi Sicurella

Erschienen in: Neurological Sciences | Ausgabe 1/2022

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Abstract

Background

The COVID-19 pandemic, induced by the worldwide spreading of the SARS-CoV-2, is well known for its clinical picture consistent with respiratory symptoms. If pulmonary complications are the most common manifestation of the disease, neurological problems are also significantly present, with complications including acute cerebrovascular events, encephalitis, Guillain-Barré and Miller Fisher syndromes, acute necrotizing hemorrhagic encephalopathy and hemophagocytic lymphohistiocytosis. These medical signs can be considered direct effects of the virus on the nervous system, para-infectious or post-infectious immune-mediated diseases, and neurological complications of the systemic effects of the SARS-CoV-2.

Case

In the present article, the encephalitis case in a 5-year-old girl positive for COVID-19 admitted to the emergency department complaining of fever and swelling in the neck is described. At this time, her neurological examination was unremarkable. Over the next few days, the fever went down and she experienced acute behavioral changes, mild confusion, and drowsiness. The brain MRI and electroencephalography (EEG) showed CNS involvement, suggestive of encephalitis.

Conclusion

The dramatic improvement of the symptoms after immunotherapy with corticosteroids reinforced the hypothesis of an immune-related mechanism.

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Titel: The case of encephalitis in a COVID-19 pediatric patient
verfasst von: Lidia Urso
Maria Grazia Distefano
Gaetano Cambula
Angela Irene Colomba
Domenico Nuzzo
Pasquale Picone
Daniela Giacomazza
Luigi Sicurella
Publikationsdatum: 19.10.2021
Verlag: Springer International Publishing
Schlagwort: COVID-19
Erschienen in: Neurological Sciences / Ausgabe 1/2022
Print ISSN: 1590-1874
Elektronische ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-021-05670-9

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