Skip to main content
Erschienen in: Journal of Clinical Monitoring and Computing 5/2016

20.08.2015 | Original Research

Continuous-wave near-infrared spectroscopy is not related to brain tissue oxygen tension

verfasst von: Thomas Kerz, Christian Beyer, Alexandra Huthmann, Darius Kalasauskas, Amr Nimer Amr, Stephan Boor, Stefan Welschehold

Erschienen in: Journal of Clinical Monitoring and Computing | Ausgabe 5/2016

Einloggen, um Zugang zu erhalten

Abstract

Near-infrared spectroscopy (NIRS) has gained acceptance for cerebral monitoring, especially during cardiac surgery, though there are few data showing its validity. We therefore aimed to correlate invasive brain tissue oxygen measurements (PtiO2) with the corresponding NIRS-values (regional oxygen saturation, rSO2). We also studied whether NIRS was able to detect ischemic events, defined as a PtiO2-value of <15 mmHg. Eleven patients were studied with invasive brain tissue oxygen monitoring and continuous-wave NIRS. PtiO2-correlation with corresponding NIRS-values was calculated. We found no correlation between PtiO2- and NIRS-readings. Measurement of rSO2 was no better than flipping a coin in the detection of cerebral ischemia when a commonly agreed ischemic PtiO2 cut-off value of <15 mmHg was chosen. Continuous-wave-NIRS was unable to reliably detect ischemic cerebral episodes, defined as a PtiO2 value <15 mmHg. Displayed NIRS-values did not correlate with invasively measured PtiO2-values. CW-NIRS should not be used for the detection of cerebral ischemia.
Literatur
1.
Zurück zum Zitat Brain Trauma Foundation, Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. Guidelines for the management of severe traumatic brain injury. VI. Indications for intracranial pressure monitoring. J Neurotrauma. 2007;24 Suppl 1:S37–44. doi:10.1089/neu.2007.9990. Brain Trauma Foundation, Bratton SL, Chestnut RM, Ghajar J, McConnell Hammond FF, Harris OA, Hartl R, Manley GT, Nemecek A, Newell DW, Rosenthal G, Schouten J, Shutter L, Timmons SD, Ullman JS, Videtta W, Wilberger JE, Wright DW. Guidelines for the management of severe traumatic brain injury. VI. Indications for intracranial pressure monitoring. J Neurotrauma. 2007;24 Suppl 1:S37–44. doi:10.​1089/​neu.​2007.​9990.
3.
4.
Zurück zum Zitat Brawanski A, Faltermeier R, Rothoerl RD, Woertgen C. Comparison of near-infrared spectroscopy and tissue p(O2) time series in patients after severe head injury and aneurysmal subarachnoid hemorrhage. J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab. 2002;22(5):605–11. doi:10.1097/00004647-200205000-00012.CrossRef Brawanski A, Faltermeier R, Rothoerl RD, Woertgen C. Comparison of near-infrared spectroscopy and tissue p(O2) time series in patients after severe head injury and aneurysmal subarachnoid hemorrhage. J Cereb Blood Flow Metab Off J Int Soc Cereb Blood Flow Metab. 2002;22(5):605–11. doi:10.​1097/​00004647-200205000-00012.CrossRef
5.
Zurück zum Zitat Leal-Noval SR, Cayuela A, Arellano-Orden V, Marin-Caballos A, Padilla V, Ferrandiz-Millon C, Corcia Y, Garcia-Alfaro C, Amaya-Villar R, Murillo-Cabezas F. Invasive and noninvasive assessment of cerebral oxygenation in patients with severe traumatic brain injury. Intensive Care Med. 2010;36(8):1309–17. doi:10.1007/s00134-010-1920-7.CrossRefPubMed Leal-Noval SR, Cayuela A, Arellano-Orden V, Marin-Caballos A, Padilla V, Ferrandiz-Millon C, Corcia Y, Garcia-Alfaro C, Amaya-Villar R, Murillo-Cabezas F. Invasive and noninvasive assessment of cerebral oxygenation in patients with severe traumatic brain injury. Intensive Care Med. 2010;36(8):1309–17. doi:10.​1007/​s00134-010-1920-7.CrossRefPubMed
7.
Zurück zum Zitat Sorensen H, Rasmussen P, Siebenmann C, Zaar M, Hvidtfeldt M, Ogoh S, Sato K, Kohl-Bareis M, Secher NH, Lundby C. Extra-cerebral oxygenation influence on near-infrared-spectroscopy-determined frontal lobe oxygenation in healthy volunteers: a comparison between INVOS-4100 and NIRO-200NX. Clin Physiol Funct Imaging. 2014;. doi:10.1111/cpf.12142. Sorensen H, Rasmussen P, Siebenmann C, Zaar M, Hvidtfeldt M, Ogoh S, Sato K, Kohl-Bareis M, Secher NH, Lundby C. Extra-cerebral oxygenation influence on near-infrared-spectroscopy-determined frontal lobe oxygenation in healthy volunteers: a comparison between INVOS-4100 and NIRO-200NX. Clin Physiol Funct Imaging. 2014;. doi:10.​1111/​cpf.​12142.
12.
Zurück zum Zitat Rosenthal G, Hemphill JC 3rd, Sorani M, Martin C, Morabito D, Obrist WD, Manley GT. Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med. 2008;36(6):1917–24. doi:10.1097/CCM.0b013e3181743d77.CrossRefPubMed Rosenthal G, Hemphill JC 3rd, Sorani M, Martin C, Morabito D, Obrist WD, Manley GT. Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. Crit Care Med. 2008;36(6):1917–24. doi:10.​1097/​CCM.​0b013e3181743d77​.CrossRefPubMed
15.
Zurück zum Zitat Buchner K, Meixensberger J, Dings J, Roosen K. Near-infrared spectroscopy—not useful to monitor cerebral oxygenation after severe brain injury. Zentralbl Neurochir. 2000;61(2):69–73.CrossRefPubMed Buchner K, Meixensberger J, Dings J, Roosen K. Near-infrared spectroscopy—not useful to monitor cerebral oxygenation after severe brain injury. Zentralbl Neurochir. 2000;61(2):69–73.CrossRefPubMed
16.
Zurück zum Zitat McLeod AD, Igielman F, Elwell C, Cope M, Smith M. Measuring cerebral oxygenation during normobaric hyperoxia: a comparison of tissue microprobes, near-infrared spectroscopy, and jugular venous oximetry in head injury. Anesth Analg. 2003;97(3):851–6.CrossRefPubMed McLeod AD, Igielman F, Elwell C, Cope M, Smith M. Measuring cerebral oxygenation during normobaric hyperoxia: a comparison of tissue microprobes, near-infrared spectroscopy, and jugular venous oximetry in head injury. Anesth Analg. 2003;97(3):851–6.CrossRefPubMed
17.
Zurück zum Zitat MacLeod DB, Ikeda K, Keifer J, Moretti E, Ames W. Validation of the CAS adult cerebral oximeter during hypoxia in healthy volunteers. Anesth Analg. 2006;102(S2):S162. MacLeod DB, Ikeda K, Keifer J, Moretti E, Ames W. Validation of the CAS adult cerebral oximeter during hypoxia in healthy volunteers. Anesth Analg. 2006;102(S2):S162.
18.
19.
21.
Zurück zum Zitat Macmillan CS, Andrews PJ. Cerebrovenous oxygen saturation monitoring: practical considerations and clinical relevance. Intensive Care Med. 2000;26(8):1028–36.CrossRefPubMed Macmillan CS, Andrews PJ. Cerebrovenous oxygen saturation monitoring: practical considerations and clinical relevance. Intensive Care Med. 2000;26(8):1028–36.CrossRefPubMed
22.
Zurück zum Zitat Gunn HCMB, Lam AM, Mayberg TS. Accuracy of continous jugular bulb venous oximetry during intracranial surgery. J Neurosurg Anesthesiol. 1995;7(3):174–7.CrossRefPubMed Gunn HCMB, Lam AM, Mayberg TS. Accuracy of continous jugular bulb venous oximetry during intracranial surgery. J Neurosurg Anesthesiol. 1995;7(3):174–7.CrossRefPubMed
23.
Zurück zum Zitat Gupta AK, Hutchinson PJ, Al-Rawi P, Gupta S, Swart M, Kirkpatrick PJ, Menon DK, Datta AK. Measuring brain tissue oxygenation compared with jugular venous oxygen saturation for monitoring cerebral oxygenation after traumatic brain injury. Anesth Analg. 1999;88(3):549–53.CrossRefPubMed Gupta AK, Hutchinson PJ, Al-Rawi P, Gupta S, Swart M, Kirkpatrick PJ, Menon DK, Datta AK. Measuring brain tissue oxygenation compared with jugular venous oxygen saturation for monitoring cerebral oxygenation after traumatic brain injury. Anesth Analg. 1999;88(3):549–53.CrossRefPubMed
24.
Zurück zum Zitat Jeong H, Jeong S, Lim HJ, Lee J, Yoo KY. Cerebral oxygen saturation measured by near-infrared spectroscopy and jugular venous bulb oxygen saturation during arthroscopic shoulder surgery in beach chair position under sevoflurane-nitrous oxide or propofol-remifentanil anesthesia. Anesthesiology. 2012;116(5):1047–56. doi:10.1097/ALN.0b013e31825154d2.CrossRefPubMed Jeong H, Jeong S, Lim HJ, Lee J, Yoo KY. Cerebral oxygen saturation measured by near-infrared spectroscopy and jugular venous bulb oxygen saturation during arthroscopic shoulder surgery in beach chair position under sevoflurane-nitrous oxide or propofol-remifentanil anesthesia. Anesthesiology. 2012;116(5):1047–56. doi:10.​1097/​ALN.​0b013e31825154d2​.CrossRefPubMed
25.
Zurück zum Zitat Taussky P, O’Neal B, Daugherty WP, Luke S, Thorpe D, Pooley RA, Evans C, Hanel RA, Freeman WD. Validation of frontal near-infrared spectroscopy as noninvasive bedside monitoring for regional cerebral blood flow in brain-injured patients. Neurosurg Focus. 2012;32(2):E2. doi:10.3171/2011.12.FOCUS11280.CrossRefPubMed Taussky P, O’Neal B, Daugherty WP, Luke S, Thorpe D, Pooley RA, Evans C, Hanel RA, Freeman WD. Validation of frontal near-infrared spectroscopy as noninvasive bedside monitoring for regional cerebral blood flow in brain-injured patients. Neurosurg Focus. 2012;32(2):E2. doi:10.​3171/​2011.​12.​FOCUS11280.CrossRefPubMed
26.
Zurück zum Zitat Ogoh S, Sato K, Okazaki K, Miyamoto T, Secher F, Sorensen H, Rasmussen P, Secher NH. A decrease in spatially resolved near-infrared spectroscopy-determined frontal lobe tissue oxygenation by phenylephrine reflects reduced skin blood flow. Anesth Analg. 2014;118(4):823–9. doi:10.1213/ANE.0000000000000145.CrossRefPubMed Ogoh S, Sato K, Okazaki K, Miyamoto T, Secher F, Sorensen H, Rasmussen P, Secher NH. A decrease in spatially resolved near-infrared spectroscopy-determined frontal lobe tissue oxygenation by phenylephrine reflects reduced skin blood flow. Anesth Analg. 2014;118(4):823–9. doi:10.​1213/​ANE.​0000000000000145​.CrossRefPubMed
29.
Zurück zum Zitat Gomersall CD, Joynt GM, Gin T, Freebairn RC, Stewart IE. Failure of the INVOS 3100 cerebral oximeter to detect complete absence of cerebral blood flow. Crit Care Med. 1997;25(7):1252–4.CrossRefPubMed Gomersall CD, Joynt GM, Gin T, Freebairn RC, Stewart IE. Failure of the INVOS 3100 cerebral oximeter to detect complete absence of cerebral blood flow. Crit Care Med. 1997;25(7):1252–4.CrossRefPubMed
30.
Zurück zum Zitat Gatto R, Hoffman W, Mueller M, Flores A, Valyi-Nagy T, Charbel FT. Frequency domain near-infrared spectroscopy technique in the assessment of brain oxygenation: a validation study in live subjects and cadavers. J Neurosci Methods. 2006;157(2):274–7. doi:10.1016/j.jneumeth.2006.04.013.CrossRefPubMed Gatto R, Hoffman W, Mueller M, Flores A, Valyi-Nagy T, Charbel FT. Frequency domain near-infrared spectroscopy technique in the assessment of brain oxygenation: a validation study in live subjects and cadavers. J Neurosci Methods. 2006;157(2):274–7. doi:10.​1016/​j.​jneumeth.​2006.​04.​013.CrossRefPubMed
31.
Zurück zum Zitat Lin PY, Roche-Labarbe N, Dehaes M, Carp S, Fenoglio A, Barbieri B, Hagan K, Grant PE, Franceschini MA. Non-invasive optical measurement of cerebral metabolism and hemodynamics in infants. J Vis Exp. 2013;73:e4379. doi:10.3791/4379.PubMed Lin PY, Roche-Labarbe N, Dehaes M, Carp S, Fenoglio A, Barbieri B, Hagan K, Grant PE, Franceschini MA. Non-invasive optical measurement of cerebral metabolism and hemodynamics in infants. J Vis Exp. 2013;73:e4379. doi:10.​3791/​4379.PubMed
32.
Zurück zum Zitat Blohm ME, Obrecht D, Hartwich J, Singer D. Effect of cerebral circulatory arrest on cerebral near-infrared spectroscopy in pediatric patients. Paediatr Anaesth. 2014;24(4):393–9. doi:10.1111/pan.12328.CrossRefPubMed Blohm ME, Obrecht D, Hartwich J, Singer D. Effect of cerebral circulatory arrest on cerebral near-infrared spectroscopy in pediatric patients. Paediatr Anaesth. 2014;24(4):393–9. doi:10.​1111/​pan.​12328.CrossRefPubMed
33.
Zurück zum Zitat Favilla CG, Mesquita RC, Mullen M, Durduran T, Lu X, Kim MN, Minkoff DL, Kasner SE, Greenberg JH, Yodh AG, Detre JA. Optical bedside monitoring of cerebral blood flow in acute ischemic stroke patients during head-of-bed manipulation. Stroke J Cereb Circ. 2014;45(5):1269–74. doi:10.1161/STROKEAHA.113.004116.CrossRef Favilla CG, Mesquita RC, Mullen M, Durduran T, Lu X, Kim MN, Minkoff DL, Kasner SE, Greenberg JH, Yodh AG, Detre JA. Optical bedside monitoring of cerebral blood flow in acute ischemic stroke patients during head-of-bed manipulation. Stroke J Cereb Circ. 2014;45(5):1269–74. doi:10.​1161/​STROKEAHA.​113.​004116.CrossRef
Metadaten
Titel
Continuous-wave near-infrared spectroscopy is not related to brain tissue oxygen tension
verfasst von
Thomas Kerz
Christian Beyer
Alexandra Huthmann
Darius Kalasauskas
Amr Nimer Amr
Stephan Boor
Stefan Welschehold
Publikationsdatum
20.08.2015
Verlag
Springer Netherlands
Erschienen in
Journal of Clinical Monitoring and Computing / Ausgabe 5/2016
Print ISSN: 1387-1307
Elektronische ISSN: 1573-2614
DOI
https://doi.org/10.1007/s10877-015-9755-y

Weitere Artikel der Ausgabe 5/2016

Journal of Clinical Monitoring and Computing 5/2016 Zur Ausgabe

Mehr Frauen im OP – weniger postoperative Komplikationen

21.05.2024 Allgemeine Chirurgie Nachrichten

Ein Frauenanteil von mindestens einem Drittel im ärztlichen Op.-Team war in einer großen retrospektiven Studie aus Kanada mit einer signifikanten Reduktion der postoperativen Morbidität assoziiert.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Delir bei kritisch Kranken – Antipsychotika versus Placebo

16.05.2024 Delir Nachrichten

Um die Langzeitfolgen eines Delirs bei kritisch Kranken zu mildern, wird vielerorts auf eine Akuttherapie mit Antipsychotika gesetzt. Eine US-amerikanische Forschungsgruppe äußert jetzt erhebliche Vorbehalte gegen dieses Vorgehen. Denn es gibt neue Daten zum Langzeiteffekt von Haloperidol bzw. Ziprasidon versus Placebo.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.