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Erschienen in: NeuroMolecular Medicine 3/2016

31.03.2016 | Review Paper

Neuro-protective Mechanisms of Lycium barbarum

verfasst von: Xiwen Xing, Fenyong Liu, Jia Xiao, Kwok Fai So

Erschienen in: NeuroMolecular Medicine | Ausgabe 3/2016

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Abstract

Neuronal diseases, including retinal disorders, stroke, Alzheimer’s disease, Parkinson’s disease and spinal cord injury, affect a large number of people worldwide and cause heavy social and economic burdens. Although many efforts have been made by scientists and clinicians to develop novel drug and healthcare strategies, few of them received satisfactory outcomes to date. Lycium barbarum is a traditional homology of medicine and food in Chinese medicine, with the capability to nourish the eyes, liver and kidneys. Recent studies have also explored its powerful neuro-protective effects on a number of neuronal diseases. In the current review, we collected key recent findings regarding the neuro-protective effects and mechanisms of L. barbarum derivatives, primarily its polysaccharide (LBP) , in some common diseases of the nervous system. A comprehensive comparison with currently available drugs has also been discussed. In general, LBP is a promising neuronal protector with potent ameliorative effects on key pathological events, such as oxidative stress, inflammation, apoptosis and cell death with minimal side effects.
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Metadaten
Titel
Neuro-protective Mechanisms of Lycium barbarum
verfasst von
Xiwen Xing
Fenyong Liu
Jia Xiao
Kwok Fai So
Publikationsdatum
31.03.2016
Verlag
Springer US
Erschienen in
NeuroMolecular Medicine / Ausgabe 3/2016
Print ISSN: 1535-1084
Elektronische ISSN: 1559-1174
DOI
https://doi.org/10.1007/s12017-016-8393-y

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