Skip to main content
Erschienen in: Insights into Imaging 4/2012

Open Access 01.08.2012 | Review

MRI of the lung (3/3)—current applications and future perspectives

verfasst von: Jürgen Biederer, S. Mirsadraee, M. Beer, F. Molinari, C. Hintze, G. Bauman, M. Both, E. J. R. Van Beek, J. Wild, M. Puderbach

Erschienen in: Insights into Imaging | Ausgabe 4/2012

Einloggen, um Zugang zu erhalten

Abstract

Background

MRI of the lung is recommended in a number of clinical indications. Having a non-radiation alternative is particularly attractive in children and young subjects, or pregnant women.

Methods

Provided there is sufficient expertise, magnetic resonance imaging (MRI) may be considered as the preferential modality in specific clinical conditions such as cystic fibrosis and acute pulmonary embolism, since additional functional information on respiratory mechanics and regional lung perfusion is provided. In other cases, such as tumours and pneumonia in children, lung MRI may be considered an alternative or adjunct to other modalities with at least similar diagnostic value.

Results

In interstitial lung disease, the clinical utility of MRI remains to be proven, but it could provide additional information that will be beneficial in research, or at some stage in clinical practice. Customised protocols for chest imaging combine fast breath-hold acquisitions from a “buffet” of sequences. Having introduced details of imaging protocols in previous articles, the aim of this manuscript is to discuss the advantages and limitations of lung MRI in current clinical practice.

Conclusion

New developments and future perspectives such as motion-compensated imaging with self-navigated sequences or fast Fourier decomposition MRI for non-contrast enhanced ventilation- and perfusion-weighted imaging of the lung are discussed.
Main Messages
MRI evolves as a third lung imaging modality, combining morphological and functional information.
It may be considered first choice in cystic fibrosis and pulmonary embolism of young and pregnant patients.
In other cases (tumours, pneumonia in children), it is an alternative or adjunct to X-ray and CT.
In interstitial lung disease, it serves for research, but the clinical value remains to be proven.
New users are advised to make themselves familiar with the particular advantages and limitations.
Literatur
1.
Zurück zum Zitat Puderbach M, Hintze C, Ley S, Eichinger M, Kauczor H-U, Biederer J (2007) MR imaging of the chest: a practical approach at 1.5T. Eur J Radiol 64:345–355PubMedCrossRef Puderbach M, Hintze C, Ley S, Eichinger M, Kauczor H-U, Biederer J (2007) MR imaging of the chest: a practical approach at 1.5T. Eur J Radiol 64:345–355PubMedCrossRef
2.
Zurück zum Zitat Biederer J, Hintze C, Fabel M, Jakob PM, Horger W, Graessner J, Bolster BD, Heller M (2011) MRI of the lung—ready…get set…go! Magnetom Flash 46:6–15 Biederer J, Hintze C, Fabel M, Jakob PM, Horger W, Graessner J, Bolster BD, Heller M (2011) MRI of the lung—ready…get set…go! Magnetom Flash 46:6–15
3.
Zurück zum Zitat Biederer J, Both M, Graessner J, Liess C, Jakob P, Reuter M, Heller M (2003) Lung morphology: fast MR imaging assessment with a volumetric interpolated breath-hold technique: initial experience with patients. Radiology 226:242–249PubMedCrossRef Biederer J, Both M, Graessner J, Liess C, Jakob P, Reuter M, Heller M (2003) Lung morphology: fast MR imaging assessment with a volumetric interpolated breath-hold technique: initial experience with patients. Radiology 226:242–249PubMedCrossRef
4.
Zurück zum Zitat Biederer J, Reuter M, Both M, Muhle C, Grimm J, Graessner J, Heller M (2002) Analysis of artefacts and detail resolution of lung MRI with breath-hold T1-weighted gradient-echo and T2-weighted fast spin-echo sequences with respiratory triggering. Eur Radiol 12:378–384PubMedCrossRef Biederer J, Reuter M, Both M, Muhle C, Grimm J, Graessner J, Heller M (2002) Analysis of artefacts and detail resolution of lung MRI with breath-hold T1-weighted gradient-echo and T2-weighted fast spin-echo sequences with respiratory triggering. Eur Radiol 12:378–384PubMedCrossRef
6.
Zurück zum Zitat Biederer J, Schoene A, Freitag S, Reuter M, Heller M (2003) Simulated pulmonary nodules implanted in a dedicated porcine chest phantom: sensitivity of MR imaging for detection. Radiology 227:475–483PubMedCrossRef Biederer J, Schoene A, Freitag S, Reuter M, Heller M (2003) Simulated pulmonary nodules implanted in a dedicated porcine chest phantom: sensitivity of MR imaging for detection. Radiology 227:475–483PubMedCrossRef
7.
Zurück zum Zitat Biederer J, Busse I, Grimm J, Reuter M, Muhle C, Freitag S, Heller M (2002) Sensitivity of MRI in detecting alveolar Infiltrates: experimental studies. Rofo 174:1033–1039PubMedCrossRef Biederer J, Busse I, Grimm J, Reuter M, Muhle C, Freitag S, Heller M (2002) Sensitivity of MRI in detecting alveolar Infiltrates: experimental studies. Rofo 174:1033–1039PubMedCrossRef
8.
Zurück zum Zitat Hintze C, Dinkel J, Biederer J, Heussel CP, Puderbach M (2010) New procedures. Comprehensive staging of lung cancer by MRI. Radiologe 50:699–705PubMedCrossRef Hintze C, Dinkel J, Biederer J, Heussel CP, Puderbach M (2010) New procedures. Comprehensive staging of lung cancer by MRI. Radiologe 50:699–705PubMedCrossRef
9.
Zurück zum Zitat Biederer J, Bauman G, Hintze C, Fabel M, Both M (2011) Magnetresonanztomographie. Der Pneumologe 8:234–242CrossRef Biederer J, Bauman G, Hintze C, Fabel M, Both M (2011) Magnetresonanztomographie. Der Pneumologe 8:234–242CrossRef
10.
Zurück zum Zitat Stern M, Wiedemann B, Wenzlaff P (2008) From registry to quality management: the German Cystic Fibrosis Quality Assessment project 1995 2006. Eur Respir J 31:29–35PubMedCrossRef Stern M, Wiedemann B, Wenzlaff P (2008) From registry to quality management: the German Cystic Fibrosis Quality Assessment project 1995 2006. Eur Respir J 31:29–35PubMedCrossRef
11.
Zurück zum Zitat Gibson RL, Burns JL, Ramsey BW (2003) Pathophysiology and management of pulmonary infections in cystic fibrosis. Am J Respir Crit Care Med 168:918–951PubMedCrossRef Gibson RL, Burns JL, Ramsey BW (2003) Pathophysiology and management of pulmonary infections in cystic fibrosis. Am J Respir Crit Care Med 168:918–951PubMedCrossRef
12.
Zurück zum Zitat de Jong PA, Mayo JR, Golmohammadi K, Nakano Y, Lequin MH, Tiddens HAWM, Aldrich J, Coxson HO, Sin DD (2006) Estimation of cancer mortality associated with repetitive computed tomography scanning. Am J Respir Crit Care Med 173:199–203PubMedCrossRef de Jong PA, Mayo JR, Golmohammadi K, Nakano Y, Lequin MH, Tiddens HAWM, Aldrich J, Coxson HO, Sin DD (2006) Estimation of cancer mortality associated with repetitive computed tomography scanning. Am J Respir Crit Care Med 173:199–203PubMedCrossRef
13.
Zurück zum Zitat Puderbach M, Eichinger M, Gahr J, Ley S, Tuengerthal S, Schmähl A, Fink C, Plathow C, Wiebel M, Müller FM, Kauczor HU (2007) Proton MRI appearance of cystic fibrosis: comparison to CT. Eur Radiol 17:716–724PubMedCrossRef Puderbach M, Eichinger M, Gahr J, Ley S, Tuengerthal S, Schmähl A, Fink C, Plathow C, Wiebel M, Müller FM, Kauczor HU (2007) Proton MRI appearance of cystic fibrosis: comparison to CT. Eur Radiol 17:716–724PubMedCrossRef
14.
Zurück zum Zitat Puderbach M, Eichinger M, Haeselbarth J, Ley S, Kopp-Schneider A, Tuengerthal S, Schmaehl A, Fink C, Plathow C, Müller FM, Kauczor HU (2007) Assessment of morphological MRI for pulmonary changes in cystic fibrosis (CF) patients: comparison to thin-section CT and chest x-ray. Invest Radiol 42:715–725PubMedCrossRef Puderbach M, Eichinger M, Haeselbarth J, Ley S, Kopp-Schneider A, Tuengerthal S, Schmaehl A, Fink C, Plathow C, Müller FM, Kauczor HU (2007) Assessment of morphological MRI for pulmonary changes in cystic fibrosis (CF) patients: comparison to thin-section CT and chest x-ray. Invest Radiol 42:715–725PubMedCrossRef
15.
Zurück zum Zitat Failo R, Wielopolski PA, Tiddens HAWM, Hop WCJ, Mucelli RP, Lequin MH (2009) Lung morphology assessment using MRI: a robust ultra-short TR/TE 2D steady state free precession sequence used in cystic fibrosis patients. Magn Reson Med 61:299–306PubMedCrossRef Failo R, Wielopolski PA, Tiddens HAWM, Hop WCJ, Mucelli RP, Lequin MH (2009) Lung morphology assessment using MRI: a robust ultra-short TR/TE 2D steady state free precession sequence used in cystic fibrosis patients. Magn Reson Med 61:299–306PubMedCrossRef
16.
Zurück zum Zitat Eichinger M, Puderbach M, Fink C, Gahr J, Ley S, Plathow C, Tuengerthal S, Zuna I, Müller F-M, Müller FM, Kauczor HU (2006) Contrast-enhanced 3D MRI of lung perfusion in children with cystic fibrosis–initial results. Eur Radiol 16:2147–2152PubMedCrossRef Eichinger M, Puderbach M, Fink C, Gahr J, Ley S, Plathow C, Tuengerthal S, Zuna I, Müller F-M, Müller FM, Kauczor HU (2006) Contrast-enhanced 3D MRI of lung perfusion in children with cystic fibrosis–initial results. Eur Radiol 16:2147–2152PubMedCrossRef
17.
Zurück zum Zitat Eibel R, Herzog P, Dietrich O, Rieger CT, Ostermann H, Reiser MF, Schoenberg SO (2006) Pulmonary abnormalities in immunocompromised patients: comparative detection with parallel acquisition MR imaging and thin-section helical CT. Radiology 241:880–891PubMedCrossRef Eibel R, Herzog P, Dietrich O, Rieger CT, Ostermann H, Reiser MF, Schoenberg SO (2006) Pulmonary abnormalities in immunocompromised patients: comparative detection with parallel acquisition MR imaging and thin-section helical CT. Radiology 241:880–891PubMedCrossRef
18.
Zurück zum Zitat Rupprecht T, Böwing B, Kuth R, Deimling M, Rascher W, Wagner M (2002) Steady-state free precession projection MRI as a potential alternative to the conventional chest X-ray in pediatric patients with suspected pneumonia. Eur Radiol 12:2752–2756PubMedCrossRef Rupprecht T, Böwing B, Kuth R, Deimling M, Rascher W, Wagner M (2002) Steady-state free precession projection MRI as a potential alternative to the conventional chest X-ray in pediatric patients with suspected pneumonia. Eur Radiol 12:2752–2756PubMedCrossRef
19.
Zurück zum Zitat Hatabu H, Gaa J, Kim D, Li W, Prasad PV, Edelman RR (1996) Pulmonary perfusion: qualitative assessment with dynamic contrast-enhanced MRI using ultra-short TE and inversion recovery turbo FLASH. Magn Reson Med 36:503–508PubMedCrossRef Hatabu H, Gaa J, Kim D, Li W, Prasad PV, Edelman RR (1996) Pulmonary perfusion: qualitative assessment with dynamic contrast-enhanced MRI using ultra-short TE and inversion recovery turbo FLASH. Magn Reson Med 36:503–508PubMedCrossRef
20.
Zurück zum Zitat Theilmann RJ, Arai TJ, Samiee A, Dubowitz DJ, Hopkins SR, Buxton RB, Prisk GK (2009) Quantitative MRI measurement of lung density must account for the change in T(2) (*) with lung inflation. J Magn Reson Imaging 30:527–534PubMedPubMedCentralCrossRef Theilmann RJ, Arai TJ, Samiee A, Dubowitz DJ, Hopkins SR, Buxton RB, Prisk GK (2009) Quantitative MRI measurement of lung density must account for the change in T(2) (*) with lung inflation. J Magn Reson Imaging 30:527–534PubMedPubMedCentralCrossRef
21.
Zurück zum Zitat Puderbach M, Risse F, Biederer J, Ley-Zaporozhan J, Ley S, Szabo G, Semmler W, Kauczor H-U (2008) In vivo Gd-DTPA concentration for MR lung perfusion measurements: assessment with computed tomography in a porcine model. Eur Radiol 18:2102–2107PubMedCrossRef Puderbach M, Risse F, Biederer J, Ley-Zaporozhan J, Ley S, Szabo G, Semmler W, Kauczor H-U (2008) In vivo Gd-DTPA concentration for MR lung perfusion measurements: assessment with computed tomography in a porcine model. Eur Radiol 18:2102–2107PubMedCrossRef
22.
Zurück zum Zitat Risse F, Eichinger M, Kauczor H-U, Semmler W, Puderbach M (2011) Improved visualization of delayed perfusion in lung MRI. Eur J Radiol 77:105–110PubMedCrossRef Risse F, Eichinger M, Kauczor H-U, Semmler W, Puderbach M (2011) Improved visualization of delayed perfusion in lung MRI. Eur J Radiol 77:105–110PubMedCrossRef
23.
Zurück zum Zitat Kuder TA, Risse F, Eichinger M, Ley S, Puderbach M, Kauczor H-U, Fink C (2008) New method for 3D parametric visualization of contrast-enhanced pulmonary perfusion MRI data. Eur Radiol 18:291–297PubMedCrossRef Kuder TA, Risse F, Eichinger M, Ley S, Puderbach M, Kauczor H-U, Fink C (2008) New method for 3D parametric visualization of contrast-enhanced pulmonary perfusion MRI data. Eur Radiol 18:291–297PubMedCrossRef
24.
Zurück zum Zitat Bhalla M, Turcios N, Aponte V, Jenkins M, Leitman BS, McCauley DI, Naidich DP (1991) Cystic fibrosis: scoring system with thin-section CT. Radiology 179:783–788PubMedCrossRef Bhalla M, Turcios N, Aponte V, Jenkins M, Leitman BS, McCauley DI, Naidich DP (1991) Cystic fibrosis: scoring system with thin-section CT. Radiology 179:783–788PubMedCrossRef
25.
Zurück zum Zitat Helbich TH, Heinz-Peer G, Eichler I, Wunderbaldinger P, Götz M, Wojnarowski C, Brasch RC, Herold CJ (1999) Cystic fibrosis: CT assessment of lung involvement in children and adults. Radiology 213:537–544PubMedCrossRef Helbich TH, Heinz-Peer G, Eichler I, Wunderbaldinger P, Götz M, Wojnarowski C, Brasch RC, Herold CJ (1999) Cystic fibrosis: CT assessment of lung involvement in children and adults. Radiology 213:537–544PubMedCrossRef
26.
Zurück zum Zitat Brody AS, Kosorok MR, Li Z, Broderick LS, Foster JL, Laxova A, Bandla H, Farrell PM (2006) Reproducibility of a scoring system for computed tomography scanning in cystic fibrosis. J Thorac Imaging 21:14–21PubMedCrossRef Brody AS, Kosorok MR, Li Z, Broderick LS, Foster JL, Laxova A, Bandla H, Farrell PM (2006) Reproducibility of a scoring system for computed tomography scanning in cystic fibrosis. J Thorac Imaging 21:14–21PubMedCrossRef
27.
Zurück zum Zitat Eichinger M, Optazaite D-E, Kopp-Schneider A, Hintze C, Biederer J, Niemann A, Mall MA, Wielpütz MO, Kauczor H-U, Puderbach M (2011) Morphologic and functional scoring of cystic fibrosis lung disease using MRI. Eur J Radiol Eichinger M, Optazaite D-E, Kopp-Schneider A, Hintze C, Biederer J, Niemann A, Mall MA, Wielpütz MO, Kauczor H-U, Puderbach M (2011) Morphologic and functional scoring of cystic fibrosis lung disease using MRI. Eur J Radiol
28.
Zurück zum Zitat de Jong PA, Tiddens HAWM (2007) Cystic fibrosis specific computed tomography scoring. Proc Am Thorac Soc 4:338–342PubMedCrossRef de Jong PA, Tiddens HAWM (2007) Cystic fibrosis specific computed tomography scoring. Proc Am Thorac Soc 4:338–342PubMedCrossRef
29.
Zurück zum Zitat Santamaria F, Grillo G, Guidi G, Rotondo A, Raia V, de Ritis G, Sarnelli P, Caterino M, Greco L (1998) Cystic fibrosis: when should high-resolution computed tomography of the chest be obtained? Pediatrics 101:908–913PubMedCrossRef Santamaria F, Grillo G, Guidi G, Rotondo A, Raia V, de Ritis G, Sarnelli P, Caterino M, Greco L (1998) Cystic fibrosis: when should high-resolution computed tomography of the chest be obtained? Pediatrics 101:908–913PubMedCrossRef
30.
Zurück zum Zitat Stein PD, Fowler SE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Leeper KV, Popovich J, Quinn DA, Sos TA, Sostman HD, Tapson VF, Wakefield TW, Weg JG, Woodard PK (2006) Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 354:2317–2327PubMedCrossRef Stein PD, Fowler SE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Leeper KV, Popovich J, Quinn DA, Sos TA, Sostman HD, Tapson VF, Wakefield TW, Weg JG, Woodard PK (2006) Multidetector computed tomography for acute pulmonary embolism. N Engl J Med 354:2317–2327PubMedCrossRef
31.
Zurück zum Zitat Oudkerk M, van Beek EJR, Wielopolski P, van Ooijen PMA, Brouwers-Kuyper EMJ, Bongaerts AHH, Berghout A (2002) Comparison of contrast-enhanced magnetic resonance angiography and conventional pulmonary angiography for the diagnosis of pulmonary embolism: a prospective study. Lancet 359:1643–1647PubMedCrossRef Oudkerk M, van Beek EJR, Wielopolski P, van Ooijen PMA, Brouwers-Kuyper EMJ, Bongaerts AHH, Berghout A (2002) Comparison of contrast-enhanced magnetic resonance angiography and conventional pulmonary angiography for the diagnosis of pulmonary embolism: a prospective study. Lancet 359:1643–1647PubMedCrossRef
32.
Zurück zum Zitat Stein PD, Gottschalk A, Sostman HD, Chenevert TL, Fowler SE, Goodman LR, Hales CA, Hull RD, Kanal E, Leeper KV Jr, Nadich DP, Sak DJ, Tapson VF, Wakefield TW, Weg JG, Woodard PK (2008) Methods of Prospective Investigation of Pulmonary Embolism Diagnosis III (PIOPED III). Semin Nucl Med 38:462–470PubMedPubMedCentralCrossRef Stein PD, Gottschalk A, Sostman HD, Chenevert TL, Fowler SE, Goodman LR, Hales CA, Hull RD, Kanal E, Leeper KV Jr, Nadich DP, Sak DJ, Tapson VF, Wakefield TW, Weg JG, Woodard PK (2008) Methods of Prospective Investigation of Pulmonary Embolism Diagnosis III (PIOPED III). Semin Nucl Med 38:462–470PubMedPubMedCentralCrossRef
33.
Zurück zum Zitat Kluge A, Luboldt W, Bachmann G (2006) Acute pulmonary embolism to the subsegmental level: diagnostic accuracy of three MRI techniques compared with 16-MDCT. AJR Am J Roentgenol 187:W7–W14PubMedCrossRef Kluge A, Luboldt W, Bachmann G (2006) Acute pulmonary embolism to the subsegmental level: diagnostic accuracy of three MRI techniques compared with 16-MDCT. AJR Am J Roentgenol 187:W7–W14PubMedCrossRef
34.
Zurück zum Zitat Kluge A, Gerriets T, Stolz E, Dill T, Mueller K-D, Mueller C, Bachmann G (2006) Pulmonary perfusion in acute pulmonary embolism: agreement of MRI and SPECT for lobar, segmental and subsegmental perfusion defects. Acta Radiol 47:933–940PubMedCrossRef Kluge A, Gerriets T, Stolz E, Dill T, Mueller K-D, Mueller C, Bachmann G (2006) Pulmonary perfusion in acute pulmonary embolism: agreement of MRI and SPECT for lobar, segmental and subsegmental perfusion defects. Acta Radiol 47:933–940PubMedCrossRef
35.
Zurück zum Zitat Kluge A, Gerriets T, Müller C, Ekinci O, Neumann T, Dill T, Bachmann G (2005) Thoracic real-time MRI: experience from 2200 examinations in acute and ill-defined thoracic diseases. Rofo 177:1513–1521PubMedCrossRef Kluge A, Gerriets T, Müller C, Ekinci O, Neumann T, Dill T, Bachmann G (2005) Thoracic real-time MRI: experience from 2200 examinations in acute and ill-defined thoracic diseases. Rofo 177:1513–1521PubMedCrossRef
36.
Zurück zum Zitat Hintze C, Biederer J, Wenz HW, Eberhardt R, Kauczor HU (2006) MRI in staging of lung cancer. Radiologe 46(251–4):256–259 Hintze C, Biederer J, Wenz HW, Eberhardt R, Kauczor HU (2006) MRI in staging of lung cancer. Radiologe 46(251–4):256–259
37.
Zurück zum Zitat Yi CA, Shin KM, Lee KS, Kim B-T, Kim H, Kwon OJ, Choi JY, Chung MJ (2008) Non-small cell lung cancer staging: efficacy comparison of integrated PET/CT versus 3.0-T whole-body MR imaging. Radiology 248:632–642PubMedCrossRef Yi CA, Shin KM, Lee KS, Kim B-T, Kim H, Kwon OJ, Choi JY, Chung MJ (2008) Non-small cell lung cancer staging: efficacy comparison of integrated PET/CT versus 3.0-T whole-body MR imaging. Radiology 248:632–642PubMedCrossRef
38.
Zurück zum Zitat Ohba Y, Nomori H, Mori T, Ikeda K, Shibata H, Kobayashi H, Shiraishi S, Katahira K (2009) Is diffusion-weighted magnetic resonance imaging superior to positron emission tomography with fludeoxyglucose F 18 in imaging non-small cell lung cancer? J Thorac Cardiovasc Surg 138:439–445PubMedCrossRef Ohba Y, Nomori H, Mori T, Ikeda K, Shibata H, Kobayashi H, Shiraishi S, Katahira K (2009) Is diffusion-weighted magnetic resonance imaging superior to positron emission tomography with fludeoxyglucose F 18 in imaging non-small cell lung cancer? J Thorac Cardiovasc Surg 138:439–445PubMedCrossRef
39.
Zurück zum Zitat Mori T, Nomori H, Ikeda K, Kawanaka K, Shiraishi S, Katahira K, Yamashita Y (2008) Diffusion-weighted magnetic resonance imaging for diagnosing malignant pulmonary nodules/masses: comparison with positron emission tomography. J Thorac Oncol 3:358–364PubMedCrossRef Mori T, Nomori H, Ikeda K, Kawanaka K, Shiraishi S, Katahira K, Yamashita Y (2008) Diffusion-weighted magnetic resonance imaging for diagnosing malignant pulmonary nodules/masses: comparison with positron emission tomography. J Thorac Oncol 3:358–364PubMedCrossRef
40.
Zurück zum Zitat Qi LP, Zhang XP, Tang L, Li J, Sun YS, Zhu GY (2009) Using diffusion-weighted MR imaging for tumor detection in the collapsed lung: a preliminary study. Eur Radiol 19:333–341PubMedCrossRef Qi LP, Zhang XP, Tang L, Li J, Sun YS, Zhu GY (2009) Using diffusion-weighted MR imaging for tumor detection in the collapsed lung: a preliminary study. Eur Radiol 19:333–341PubMedCrossRef
41.
Zurück zum Zitat Akata S, Kajiwara N, Park J, Yoshimura M, Kakizaki D, Abe K, Hirano T, Ohira T, Tsuboi M, Kato H (2008) Evaluation of chest wall invasion by lung cancer using respiratory dynamic MRI. J Med Imaging Radiat Oncol 52:36–39PubMedCrossRef Akata S, Kajiwara N, Park J, Yoshimura M, Kakizaki D, Abe K, Hirano T, Ohira T, Tsuboi M, Kato H (2008) Evaluation of chest wall invasion by lung cancer using respiratory dynamic MRI. J Med Imaging Radiat Oncol 52:36–39PubMedCrossRef
42.
Zurück zum Zitat Ohno Y, Koyama H, Takenaka D, Nogami M, Maniwa Y, Nishimura Y, Ohbayashi C, Sugimura K (2008) Dynamic MRI, dynamic multidetector-row computed tomography (MDCT), and coregistered 2-[fluorine-18]-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET)/CT: comparative study of capability for management of pulmonary nodules. J Magn Reson Imaging 27:1284–1295PubMedCrossRef Ohno Y, Koyama H, Takenaka D, Nogami M, Maniwa Y, Nishimura Y, Ohbayashi C, Sugimura K (2008) Dynamic MRI, dynamic multidetector-row computed tomography (MDCT), and coregistered 2-[fluorine-18]-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET)/CT: comparative study of capability for management of pulmonary nodules. J Magn Reson Imaging 27:1284–1295PubMedCrossRef
43.
Zurück zum Zitat Pauls S, Mottaghy FM, Schmidt SA, Krüger S, Möller P, Brambs H-J, Wunderlich A (2008) Evaluation of lung tumor perfusion by dynamic contrast-enhanced MRI. Magn Reson Imaging 26:1334–1341PubMedCrossRef Pauls S, Mottaghy FM, Schmidt SA, Krüger S, Möller P, Brambs H-J, Wunderlich A (2008) Evaluation of lung tumor perfusion by dynamic contrast-enhanced MRI. Magn Reson Imaging 26:1334–1341PubMedCrossRef
44.
Zurück zum Zitat Hebestreit A, Schultz G, Trusen A, Hebestreit H (2004) Follow-up of acute pulmonary complications in cystic fibrosis by magnetic resonance imaging: a pilot study. Acta Paediatr 93:414–416PubMedCrossRef Hebestreit A, Schultz G, Trusen A, Hebestreit H (2004) Follow-up of acute pulmonary complications in cystic fibrosis by magnetic resonance imaging: a pilot study. Acta Paediatr 93:414–416PubMedCrossRef
45.
Zurück zum Zitat Cohen MD, Eigen H, Scott PH, Tepper R, Cory DA, Smith JA, Scales RL (1986) Magnetic resonance imaging of inflammatory lung disorders: preliminary studies in children. Pediatr Pulmonol 2:211–217PubMedCrossRef Cohen MD, Eigen H, Scott PH, Tepper R, Cory DA, Smith JA, Scales RL (1986) Magnetic resonance imaging of inflammatory lung disorders: preliminary studies in children. Pediatr Pulmonol 2:211–217PubMedCrossRef
46.
Zurück zum Zitat Abolmaali ND, Schmitt J, Krauss S, Bretz F, Deimling M, Jacobi V, Vogl TJ (2004) MR imaging of lung parenchyma at 0.2T: evaluation of imaging techniques, comparative study with chest radiography and interobserver analysis. Eur Radiol 14:703–708PubMedCrossRef Abolmaali ND, Schmitt J, Krauss S, Bretz F, Deimling M, Jacobi V, Vogl TJ (2004) MR imaging of lung parenchyma at 0.2T: evaluation of imaging techniques, comparative study with chest radiography and interobserver analysis. Eur Radiol 14:703–708PubMedCrossRef
47.
Zurück zum Zitat Wagner M, Böwing B, Kuth R, Deimling M, Rascher W, Rupprecht T (2001) Low field thoracic MRI–a fast and radiation free routine imaging modality in children. Magn Reson Imaging 19:975–983PubMedCrossRef Wagner M, Böwing B, Kuth R, Deimling M, Rascher W, Rupprecht T (2001) Low field thoracic MRI–a fast and radiation free routine imaging modality in children. Magn Reson Imaging 19:975–983PubMedCrossRef
48.
Zurück zum Zitat Peltola V, Ruuskanen O, Svedström E (2008) Magnetic resonance imaging of lung infections in children. Pediatr Radiol 38:1225–1231PubMedCrossRef Peltola V, Ruuskanen O, Svedström E (2008) Magnetic resonance imaging of lung infections in children. Pediatr Radiol 38:1225–1231PubMedCrossRef
49.
Zurück zum Zitat Hirsch W, Sorge I, Krohmer S, Weber D, Meier K, Till H (2008) MRI of the lungs in children. Eur J Radiol 68:278–288PubMedCrossRef Hirsch W, Sorge I, Krohmer S, Weber D, Meier K, Till H (2008) MRI of the lungs in children. Eur J Radiol 68:278–288PubMedCrossRef
50.
Zurück zum Zitat Yi CA, Lee KS, Han J, Chung MP, Chung MJ, Shin KM (2008) 3-T MRI for differentiating inflammation- and fibrosis-predominant lesions of usual and nonspecific interstitial pneumonia: comparison study with pathologic correlation. AJR Am J Roentgenol 190:878–885PubMedCrossRef Yi CA, Lee KS, Han J, Chung MP, Chung MJ, Shin KM (2008) 3-T MRI for differentiating inflammation- and fibrosis-predominant lesions of usual and nonspecific interstitial pneumonia: comparison study with pathologic correlation. AJR Am J Roentgenol 190:878–885PubMedCrossRef
51.
Zurück zum Zitat Montella S, Santamaria F, Salvatore M, Pignata C, Maglione M, Iacotucci P, Mollica C (2009) Assessment of chest high-field magnetic resonance imaging in children and young adults with noncystic fibrosis chronic lung disease: comparison to high-resolution computed tomography and correlation with pulmonary function. Invest Radiol 44:532–538PubMedCrossRef Montella S, Santamaria F, Salvatore M, Pignata C, Maglione M, Iacotucci P, Mollica C (2009) Assessment of chest high-field magnetic resonance imaging in children and young adults with noncystic fibrosis chronic lung disease: comparison to high-resolution computed tomography and correlation with pulmonary function. Invest Radiol 44:532–538PubMedCrossRef
52.
Zurück zum Zitat Mannino DM, Doherty DE, Sonia Buist A (2006) Global Initiative on Obstructive Lung Disease (GOLD) classification of lung disease and mortality: findings from the Atherosclerosis Risk in Communities (ARIC) study. Respir Med 100:115–122PubMedCrossRef Mannino DM, Doherty DE, Sonia Buist A (2006) Global Initiative on Obstructive Lung Disease (GOLD) classification of lung disease and mortality: findings from the Atherosclerosis Risk in Communities (ARIC) study. Respir Med 100:115–122PubMedCrossRef
53.
Zurück zum Zitat Bankier AA, O’Donnell CR, Mai VM, Storey P, De Maertelaer V, Edelman RR, Chen Q (2004) Impact of lung volume on MR signal intensity changes of the lung parenchyma. J Magn Reson Imaging 20:961–966PubMedCrossRef Bankier AA, O’Donnell CR, Mai VM, Storey P, De Maertelaer V, Edelman RR, Chen Q (2004) Impact of lung volume on MR signal intensity changes of the lung parenchyma. J Magn Reson Imaging 20:961–966PubMedCrossRef
54.
Zurück zum Zitat Ley-Zaporozhan J, Ley S, Kauczor H-U (2008) Morphological and functional imaging in COPD with CT and MRI: present and future. Eur Radiol 18:510–521PubMedCrossRef Ley-Zaporozhan J, Ley S, Kauczor H-U (2008) Morphological and functional imaging in COPD with CT and MRI: present and future. Eur Radiol 18:510–521PubMedCrossRef
55.
Zurück zum Zitat Decramer M, Gosselink R, Troosters T, Verschueren M, Evers G (1997) Muscle weakness is related to utilization of health care resources in COPD patients. Eur Respir J 10:417–423PubMedCrossRef Decramer M, Gosselink R, Troosters T, Verschueren M, Evers G (1997) Muscle weakness is related to utilization of health care resources in COPD patients. Eur Respir J 10:417–423PubMedCrossRef
56.
Zurück zum Zitat Henderson AC, Ingenito EP, Salcedo ES, Moy ML, Reilly JJ, Lutchen KR (2007) Dynamic lung mechanics in late-stage emphysema before and after lung volume reduction surgery. Respir Physiol Neurobiol 155:234–242PubMedCrossRef Henderson AC, Ingenito EP, Salcedo ES, Moy ML, Reilly JJ, Lutchen KR (2007) Dynamic lung mechanics in late-stage emphysema before and after lung volume reduction surgery. Respir Physiol Neurobiol 155:234–242PubMedCrossRef
57.
Zurück zum Zitat Suga K, Tsukuda T, Awaya H, Takano K, Koike S, Matsunaga N, Sugi K, Esato K (1999) Impaired respiratory mechanics in pulmonary emphysema: evaluation with dynamic breathing MRI. J Magn Reson Imaging 10:510–520PubMedCrossRef Suga K, Tsukuda T, Awaya H, Takano K, Koike S, Matsunaga N, Sugi K, Esato K (1999) Impaired respiratory mechanics in pulmonary emphysema: evaluation with dynamic breathing MRI. J Magn Reson Imaging 10:510–520PubMedCrossRef
58.
Zurück zum Zitat Iwasawa T, Yoshiike Y, Saito K, Kagei S, Gotoh T, Matsubara S (2000) Paradoxical motion of the hemidiaphragm in patients with emphysema. J Thorac Imaging 15:191–195PubMedCrossRef Iwasawa T, Yoshiike Y, Saito K, Kagei S, Gotoh T, Matsubara S (2000) Paradoxical motion of the hemidiaphragm in patients with emphysema. J Thorac Imaging 15:191–195PubMedCrossRef
59.
Zurück zum Zitat Iwasawa T, Kagei S, Gotoh T, Yoshiike Y, Matsushita K, Kurihara H, Saito K, Matsubara S (2002) Magnetic resonance analysis of abnormal diaphragmatic motion in patients with emphysema. Eur Respir J 19:225–231PubMedCrossRef Iwasawa T, Kagei S, Gotoh T, Yoshiike Y, Matsushita K, Kurihara H, Saito K, Matsubara S (2002) Magnetic resonance analysis of abnormal diaphragmatic motion in patients with emphysema. Eur Respir J 19:225–231PubMedCrossRef
60.
Zurück zum Zitat Iwasawa T, Takahashi H, Ogura T, Asakura A, Gotoh T, Kagei S, J-ichi N, Obara M, Inoue T (2007) Correlation of lung parenchymal MR signal intensity with pulmonary function tests and quantitative computed tomography (CT) evaluation: a pilot study. J Magn Reson Imaging 26:1530–1536PubMedCrossRef Iwasawa T, Takahashi H, Ogura T, Asakura A, Gotoh T, Kagei S, J-ichi N, Obara M, Inoue T (2007) Correlation of lung parenchymal MR signal intensity with pulmonary function tests and quantitative computed tomography (CT) evaluation: a pilot study. J Magn Reson Imaging 26:1530–1536PubMedCrossRef
61.
Zurück zum Zitat Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO, Pare DP (2004) The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 350:2645–2653PubMedCrossRef Hogg JC, Chu F, Utokaparch S, Woods R, Elliott WM, Buzatu L, Cherniack RM, Rogers RM, Sciurba FC, Coxson HO, Pare DP (2004) The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 350:2645–2653PubMedCrossRef
62.
Zurück zum Zitat Heussel CP, Ley S, Biedermann A, Rist A, Gast KK, Schreiber WG, Kauczor H-U (2004) Respiratory lumenal change of the pharynx and trachea in normal subjects and COPD patients: assessment by cine-MRI. Eur Radiol 14:2188–2197PubMedCrossRef Heussel CP, Ley S, Biedermann A, Rist A, Gast KK, Schreiber WG, Kauczor H-U (2004) Respiratory lumenal change of the pharynx and trachea in normal subjects and COPD patients: assessment by cine-MRI. Eur Radiol 14:2188–2197PubMedCrossRef
63.
Zurück zum Zitat Euler US, Liljestrand G (1946) Observations on the pulmonary arterial blood pressure in the cat. Acta Physiol Scand 12:301–320CrossRef Euler US, Liljestrand G (1946) Observations on the pulmonary arterial blood pressure in the cat. Acta Physiol Scand 12:301–320CrossRef
64.
65.
Zurück zum Zitat Morrison NJ, Abboud RT, Müller NL, Miller RR, Gibson NN, Nelems B, Evans KG (1990) Pulmonary capillary blood volume in emphysema. Am Rev Respir Dis 141:53–61PubMedCrossRef Morrison NJ, Abboud RT, Müller NL, Miller RR, Gibson NN, Nelems B, Evans KG (1990) Pulmonary capillary blood volume in emphysema. Am Rev Respir Dis 141:53–61PubMedCrossRef
66.
Zurück zum Zitat Cederlund K, Högberg S, Jorfeldt L, Larsen F, Norman M, Rasmussen E, Tylén U (2003) Lung perfusion scintigraphy prior to lung volume reduction surgery. Acta Radiol 44:246–251PubMedCrossRef Cederlund K, Högberg S, Jorfeldt L, Larsen F, Norman M, Rasmussen E, Tylén U (2003) Lung perfusion scintigraphy prior to lung volume reduction surgery. Acta Radiol 44:246–251PubMedCrossRef
67.
Zurück zum Zitat Sandek K, Bratel T, Lagerstrand L, Rosell H (2002) Relationship between lung function, ventilation-perfusion inequality and extent of emphysema as assessed by high-resolution computed tomography. Respir Med 96:934–943PubMedCrossRef Sandek K, Bratel T, Lagerstrand L, Rosell H (2002) Relationship between lung function, ventilation-perfusion inequality and extent of emphysema as assessed by high-resolution computed tomography. Respir Med 96:934–943PubMedCrossRef
68.
Zurück zum Zitat Ley-Zaporozhan J, Ley S, Eberhardt R, Weinheimer O, Fink C, Puderbach M, Eichinger M, Herth F, Kauczor H-U (2007) Assessment of the relationship between lung parenchymal destruction and impaired pulmonary perfusion on a lobar level in patients with emphysema. Eur J Radiol 63:76–83PubMedCrossRef Ley-Zaporozhan J, Ley S, Eberhardt R, Weinheimer O, Fink C, Puderbach M, Eichinger M, Herth F, Kauczor H-U (2007) Assessment of the relationship between lung parenchymal destruction and impaired pulmonary perfusion on a lobar level in patients with emphysema. Eur J Radiol 63:76–83PubMedCrossRef
69.
Zurück zum Zitat Sergiacomi G, Sodani G, Fabiano S, Manenti G, Spinelli A, Konda D, Di Roma M, Schillaci O, Simonetti G (2003) MRI lung perfusion 2D dynamic breath-hold technique in patients with severe emphysema. In Vivo 17:319–324PubMed Sergiacomi G, Sodani G, Fabiano S, Manenti G, Spinelli A, Konda D, Di Roma M, Schillaci O, Simonetti G (2003) MRI lung perfusion 2D dynamic breath-hold technique in patients with severe emphysema. In Vivo 17:319–324PubMed
70.
Zurück zum Zitat Fink C, Puderbach M, Bock M, Lodemann K-P, Zuna I, Schmähl A, Delorme S, Kauczor H-U (2004) Regional lung perfusion: assessment with partially parallel three-dimensional MR imaging. Radiology 231:175–184PubMedCrossRef Fink C, Puderbach M, Bock M, Lodemann K-P, Zuna I, Schmähl A, Delorme S, Kauczor H-U (2004) Regional lung perfusion: assessment with partially parallel three-dimensional MR imaging. Radiology 231:175–184PubMedCrossRef
71.
Zurück zum Zitat Ohno Y, Koyama H, Nogami M, Takenaka D, Matsumoto S, Yoshimura M, Kotani Y, Sugimura K (2007) Postoperative lung function in lung cancer patients: comparative analysis of predictive capability of MRI, CT, and SPECT. AJR Am J Roentgenol 189:400–408PubMedCrossRef Ohno Y, Koyama H, Nogami M, Takenaka D, Matsumoto S, Yoshimura M, Kotani Y, Sugimura K (2007) Postoperative lung function in lung cancer patients: comparative analysis of predictive capability of MRI, CT, and SPECT. AJR Am J Roentgenol 189:400–408PubMedCrossRef
72.
Zurück zum Zitat Molinari F, Fink C, Risse F, Tuengerthal S, Bonomo L, Kauczor H-U (2006) Assessment of differential pulmonary blood flow using perfusion magnetic resonance imaging: comparison with radionuclide perfusion scintigraphy. Invest Radiol 41:624–630PubMedCrossRef Molinari F, Fink C, Risse F, Tuengerthal S, Bonomo L, Kauczor H-U (2006) Assessment of differential pulmonary blood flow using perfusion magnetic resonance imaging: comparison with radionuclide perfusion scintigraphy. Invest Radiol 41:624–630PubMedCrossRef
73.
Zurück zum Zitat Amundsen T, Torheim G, Kvistad KA, Waage A, Bjermer L, Nordlid KK, Johnsen H, Asberg A, Haraldseth O (2002) Perfusion abnormalities in pulmonary embolism studied with perfusion MRI and ventilation-perfusion scintigraphy: an intra-modality and inter-modality agreement study. J Magn Reson Imaging 15:386–394PubMedCrossRef Amundsen T, Torheim G, Kvistad KA, Waage A, Bjermer L, Nordlid KK, Johnsen H, Asberg A, Haraldseth O (2002) Perfusion abnormalities in pulmonary embolism studied with perfusion MRI and ventilation-perfusion scintigraphy: an intra-modality and inter-modality agreement study. J Magn Reson Imaging 15:386–394PubMedCrossRef
74.
Zurück zum Zitat Alford SK, van Beek EJR, McLennan G, Hoffman EA (2010) Heterogeneity of pulmonary perfusion as a mechanistic image-based phenotype in emphysema susceptible smokers. Proc Natl Acad Sci USA 107:7485–7490PubMedPubMedCentralCrossRef Alford SK, van Beek EJR, McLennan G, Hoffman EA (2010) Heterogeneity of pulmonary perfusion as a mechanistic image-based phenotype in emphysema susceptible smokers. Proc Natl Acad Sci USA 107:7485–7490PubMedPubMedCentralCrossRef
75.
Zurück zum Zitat Ohno Y, Higashino T, Takenaka D, Sugimoto K, Yoshikawa T, Kawai H, Fujii M, Hatabu H, Sugimura K (2004) MR angiography with sensitivity encoding (SENSE) for suspected pulmonary embolism: comparison with MDCT and ventilation-perfusion scintigraphy. AJR Am J Roentgenol 183:91–98PubMedCrossRef Ohno Y, Higashino T, Takenaka D, Sugimoto K, Yoshikawa T, Kawai H, Fujii M, Hatabu H, Sugimura K (2004) MR angiography with sensitivity encoding (SENSE) for suspected pulmonary embolism: comparison with MDCT and ventilation-perfusion scintigraphy. AJR Am J Roentgenol 183:91–98PubMedCrossRef
76.
Zurück zum Zitat Ohno Y, Hatabu H, Murase K, Higashino T, Kawamitsu H, Watanabe H, Takenaka D, Fujii M, Sugimura K (2004) Quantitative assessment of regional pulmonary perfusion in the entire lung using three-dimensional ultrafast dynamic contrast-enhanced magnetic resonance imaging: preliminary experience in 40 subjects. J Magn Reson Imaging 20:353–365PubMedCrossRef Ohno Y, Hatabu H, Murase K, Higashino T, Kawamitsu H, Watanabe H, Takenaka D, Fujii M, Sugimura K (2004) Quantitative assessment of regional pulmonary perfusion in the entire lung using three-dimensional ultrafast dynamic contrast-enhanced magnetic resonance imaging: preliminary experience in 40 subjects. J Magn Reson Imaging 20:353–365PubMedCrossRef
77.
Zurück zum Zitat Müller NL, Mayo JR, Zwirewich CV (1992) Value of MR imaging in the evaluation of chronic infiltrative lung diseases: comparison with CT. AJR Am J Roentgenol 158:1205–1209PubMedCrossRef Müller NL, Mayo JR, Zwirewich CV (1992) Value of MR imaging in the evaluation of chronic infiltrative lung diseases: comparison with CT. AJR Am J Roentgenol 158:1205–1209PubMedCrossRef
78.
Zurück zum Zitat Rieger C, Herzog P, Eibel R, Fiegl M, Ostermann H (2008) Pulmonary MRI–a new approach for the evaluation of febrile neutropenic patients with malignancies. Support Care Cancer 16:599–606PubMedCrossRef Rieger C, Herzog P, Eibel R, Fiegl M, Ostermann H (2008) Pulmonary MRI–a new approach for the evaluation of febrile neutropenic patients with malignancies. Support Care Cancer 16:599–606PubMedCrossRef
79.
Zurück zum Zitat Lutterbey G, Gieseke J, von Falkenhausen M, Morakkabati N, Schild H (2005) Lung MRI at 3.0T: a comparison of helical CT and high-field MRI in the detection of diffuse lung disease. Eur Radiol 15:324–328PubMedCrossRef Lutterbey G, Gieseke J, von Falkenhausen M, Morakkabati N, Schild H (2005) Lung MRI at 3.0T: a comparison of helical CT and high-field MRI in the detection of diffuse lung disease. Eur Radiol 15:324–328PubMedCrossRef
80.
Zurück zum Zitat Lutterbey G, Grohé C, Gieseke J, von Falkenhausen M, Morakkabati N, Wattjes MP, Manka R, Trog D, Schild HH (2007) Initial experience with lung-MRI at 3.0T: comparison with CT and clinical data in the evaluation of interstitial lung disease activity. Eur J Radiol 61:256–261PubMedCrossRef Lutterbey G, Grohé C, Gieseke J, von Falkenhausen M, Morakkabati N, Wattjes MP, Manka R, Trog D, Schild HH (2007) Initial experience with lung-MRI at 3.0T: comparison with CT and clinical data in the evaluation of interstitial lung disease activity. Eur J Radiol 61:256–261PubMedCrossRef
81.
Zurück zum Zitat McFadden RG, Carr TJ, Wood TE (1987) Proton magnetic resonance imaging to stage activity of interstitial lung disease. Chest 92:31–39PubMedCrossRef McFadden RG, Carr TJ, Wood TE (1987) Proton magnetic resonance imaging to stage activity of interstitial lung disease. Chest 92:31–39PubMedCrossRef
82.
Zurück zum Zitat Berthezène Y, Vexler V, Kuwatsuru R, Rosenau W, Mühler A, Clément O, Price DC, Brasch RC (1992) Differentiation of alveolitis and pulmonary fibrosis with a macromolecular MR imaging contrast agent. Radiology 185:97–103PubMedCrossRef Berthezène Y, Vexler V, Kuwatsuru R, Rosenau W, Mühler A, Clément O, Price DC, Brasch RC (1992) Differentiation of alveolitis and pulmonary fibrosis with a macromolecular MR imaging contrast agent. Radiology 185:97–103PubMedCrossRef
83.
Zurück zum Zitat Gaeta M, Blandino A, Scribano E, Minutoli F, Barone M, Andò F, Pandolfo I (2000) Chronic infiltrative lung diseases: value of gadolinium-enhanced MRI in the evaluation of disease activity–early report. Chest 117:1173–1178PubMedCrossRef Gaeta M, Blandino A, Scribano E, Minutoli F, Barone M, Andò F, Pandolfo I (2000) Chronic infiltrative lung diseases: value of gadolinium-enhanced MRI in the evaluation of disease activity–early report. Chest 117:1173–1178PubMedCrossRef
84.
Zurück zum Zitat Jacob RE, Amidan BG, Soelberg J, Minard KR (2010) In vivo MRI of altered proton signal intensity and T2 relaxation in a bleomycin model of pulmonary inflammation and fibrosis. J Magn Reson Imaging 31:1091–1099PubMedCrossRef Jacob RE, Amidan BG, Soelberg J, Minard KR (2010) In vivo MRI of altered proton signal intensity and T2 relaxation in a bleomycin model of pulmonary inflammation and fibrosis. J Magn Reson Imaging 31:1091–1099PubMedCrossRef
85.
Zurück zum Zitat Weick S, Oechsner M, Blaimer M, Breuer H, Köstler H, Hahn D (2009) Self -gated 3D FLASH imaging of the human lung under free breathing using DC signals. Proceedings 17th Scientific Meeting, ISMRM Weick S, Oechsner M, Blaimer M, Breuer H, Köstler H, Hahn D (2009) Self -gated 3D FLASH imaging of the human lung under free breathing using DC signals. Proceedings 17th Scientific Meeting, ISMRM
86.
Zurück zum Zitat Song HK, Dougherty L (2000) k-space weighted image contrast (KWIC) for contrast manipulation in projection reconstruction MRI. Magn Reson Med 44:825–832PubMedCrossRef Song HK, Dougherty L (2000) k-space weighted image contrast (KWIC) for contrast manipulation in projection reconstruction MRI. Magn Reson Med 44:825–832PubMedCrossRef
87.
Zurück zum Zitat Song HK, Dougherty L (2004) Dynamic MRI with projection reconstruction and KWIC processing for simultaneous high spatial and temporal resolution. Magn Reson Med 52:815–824PubMedCrossRef Song HK, Dougherty L (2004) Dynamic MRI with projection reconstruction and KWIC processing for simultaneous high spatial and temporal resolution. Magn Reson Med 52:815–824PubMedCrossRef
88.
Zurück zum Zitat Lin W, Guo J, Rosen MA, Song HK (2008) Respiratory motion-compensated radial dynamic contrast-enhanced (DCE)-MRI of chest and abdominal lesions. Magn Reson Med 60:1135–1146PubMedPubMedCentralCrossRef Lin W, Guo J, Rosen MA, Song HK (2008) Respiratory motion-compensated radial dynamic contrast-enhanced (DCE)-MRI of chest and abdominal lesions. Magn Reson Med 60:1135–1146PubMedPubMedCentralCrossRef
89.
Zurück zum Zitat Bauman G, Puderbach M, Deimling M, Jellus V, Chefd’hotel C, Dinkel J, Hintze C, Kauczor H-U, Schad LR (2009) Non-contrast-enhanced perfusion and ventilation assessment of the human lung by means of fourier decomposition in proton MRI. Magn Reson Med 62:656–664PubMedCrossRef Bauman G, Puderbach M, Deimling M, Jellus V, Chefd’hotel C, Dinkel J, Hintze C, Kauczor H-U, Schad LR (2009) Non-contrast-enhanced perfusion and ventilation assessment of the human lung by means of fourier decomposition in proton MRI. Magn Reson Med 62:656–664PubMedCrossRef
90.
Zurück zum Zitat Chefd’hotel C, Hermosillo G, Faugeras O (2002) Flows of Diffeomorphisms for Multimodal Image Registration. Proceedings of the IEEE International Symposium on Biomedical Imaging (ISBI’2002), Piscataway, NJ, USA: Institute of Electrical and Electronics Engineers:753–756 Chefd’hotel C, Hermosillo G, Faugeras O (2002) Flows of Diffeomorphisms for Multimodal Image Registration. Proceedings of the IEEE International Symposium on Biomedical Imaging (ISBI’2002), Piscataway, NJ, USA: Institute of Electrical and Electronics Engineers:753–756
91.
Zurück zum Zitat Suga K, Ogasawara N, Okada M, Tsukuda T, Matsunaga N, Miyazaki M (2002) Lung perfusion impairments in pulmonary embolic and airway obstruction with noncontrast MR imaging. J Appl Physiol 92:2439–2451PubMedCrossRef Suga K, Ogasawara N, Okada M, Tsukuda T, Matsunaga N, Miyazaki M (2002) Lung perfusion impairments in pulmonary embolic and airway obstruction with noncontrast MR imaging. J Appl Physiol 92:2439–2451PubMedCrossRef
92.
Zurück zum Zitat Bauman G, Lützen U, Ullrich M, Gaass T, Dinkel J, Elke G, Meybohm P, Frerichs I, Hoffmann B, Borggrefe J, Knuth HC, Schupp J, Prüm H, Eichinger M, Pudebach M, Biederer J, Hintze C (2011) Pulmonary functional imaging: qualitative comparison of Fourier decomposition MR imaging with SPECT/CT in porcine lung. Radiology 260:551–559PubMedCrossRef Bauman G, Lützen U, Ullrich M, Gaass T, Dinkel J, Elke G, Meybohm P, Frerichs I, Hoffmann B, Borggrefe J, Knuth HC, Schupp J, Prüm H, Eichinger M, Pudebach M, Biederer J, Hintze C (2011) Pulmonary functional imaging: qualitative comparison of Fourier decomposition MR imaging with SPECT/CT in porcine lung. Radiology 260:551–559PubMedCrossRef
93.
Zurück zum Zitat Pichler BJ, Judenhofer M, Pfannenberg C (2008) Multimodal imaging approaches: PET/CT and PET/MRI. In: Handb Exp Pharmacol:109–132 Pichler BJ, Judenhofer M, Pfannenberg C (2008) Multimodal imaging approaches: PET/CT and PET/MRI. In: Handb Exp Pharmacol:109–132
94.
Zurück zum Zitat Shao Y, Cherry SR, Farahani K, Meadors K, Siegel S, Silverman RW, Marsden PK (1997) Simultaneous PET and MR imaging. Phys Med Biol 42:1965–1970PubMedCrossRef Shao Y, Cherry SR, Farahani K, Meadors K, Siegel S, Silverman RW, Marsden PK (1997) Simultaneous PET and MR imaging. Phys Med Biol 42:1965–1970PubMedCrossRef
95.
Zurück zum Zitat Pichler BJ, Kolb A, Nägele T, Schlemmer H-P (2010) PET/MRI: paving the way for the next generation of clinical multimodality imaging applications. J Nucl Med 51:333–336PubMedCrossRef Pichler BJ, Kolb A, Nägele T, Schlemmer H-P (2010) PET/MRI: paving the way for the next generation of clinical multimodality imaging applications. J Nucl Med 51:333–336PubMedCrossRef
96.
Zurück zum Zitat Zaidi H, Ojha N, Morich M, Griesmer J, Hu Z, Maniawski P, Ratib O, Izquierdo-Garcia D, Fayad ZA, Shao L (2011) Design and performance evaluation of a whole-body Ingenuity TF PET-MRI system. Phys Med Biol 56:3091–3106PubMedPubMedCentralCrossRef Zaidi H, Ojha N, Morich M, Griesmer J, Hu Z, Maniawski P, Ratib O, Izquierdo-Garcia D, Fayad ZA, Shao L (2011) Design and performance evaluation of a whole-body Ingenuity TF PET-MRI system. Phys Med Biol 56:3091–3106PubMedPubMedCentralCrossRef
97.
Zurück zum Zitat Pichler BJ, Judenhofer MS, Wehrl HF (2008) PET/MRI hybrid imaging: devices and initial results. Eur Radiol 18:1077–1086PubMedCrossRef Pichler BJ, Judenhofer MS, Wehrl HF (2008) PET/MRI hybrid imaging: devices and initial results. Eur Radiol 18:1077–1086PubMedCrossRef
98.
Zurück zum Zitat Wehrl HF, Judenhofer MS, Wiehr S, Pichler BJ (2009) Pre-clinical PET/MR: technological advances and new perspectives in biomedical research. Eur J Nucl Med Mol Imaging 36(Suppl 1):S56–S68PubMedCrossRef Wehrl HF, Judenhofer MS, Wiehr S, Pichler BJ (2009) Pre-clinical PET/MR: technological advances and new perspectives in biomedical research. Eur J Nucl Med Mol Imaging 36(Suppl 1):S56–S68PubMedCrossRef
99.
Zurück zum Zitat Ratib O, Beyer T (2011) Whole-body hybrid PET/MRI: ready for clinical use? Eur J Nucl Med Mol Imaging 38:992–995PubMedCrossRef Ratib O, Beyer T (2011) Whole-body hybrid PET/MRI: ready for clinical use? Eur J Nucl Med Mol Imaging 38:992–995PubMedCrossRef
100.
Zurück zum Zitat Antoch G, Bockisch A (2009) Combined PET/MRI: a new dimension in whole-body oncology imaging? Eur J Nucl Med Mol Imaging 36(Suppl 1):S113–S120PubMedCrossRef Antoch G, Bockisch A (2009) Combined PET/MRI: a new dimension in whole-body oncology imaging? Eur J Nucl Med Mol Imaging 36(Suppl 1):S113–S120PubMedCrossRef
101.
Zurück zum Zitat Antoch G, Vogt FM, Freudenberg LS, Nazaradeh F, Goehde SC, Barkhausen J, Dahmen G, Bockisch A, Debatin JF, Ruehm SG (2003) Whole-body dual-modality PET/CT and whole-body MRI for tumor staging in oncology. JAMA 290:3199–3206PubMedCrossRef Antoch G, Vogt FM, Freudenberg LS, Nazaradeh F, Goehde SC, Barkhausen J, Dahmen G, Bockisch A, Debatin JF, Ruehm SG (2003) Whole-body dual-modality PET/CT and whole-body MRI for tumor staging in oncology. JAMA 290:3199–3206PubMedCrossRef
Metadaten
Titel
MRI of the lung (3/3)—current applications and future perspectives
verfasst von
Jürgen Biederer
S. Mirsadraee
M. Beer
F. Molinari
C. Hintze
G. Bauman
M. Both
E. J. R. Van Beek
J. Wild
M. Puderbach
Publikationsdatum
01.08.2012
Verlag
Springer Berlin Heidelberg
Erschienen in
Insights into Imaging / Ausgabe 4/2012
Elektronische ISSN: 1869-4101
DOI
https://doi.org/10.1007/s13244-011-0142-z

Weitere Artikel der Ausgabe 4/2012

Insights into Imaging 4/2012 Zur Ausgabe

Mammakarzinom: Brustdichte beeinflusst rezidivfreies Überleben

26.05.2024 Mammakarzinom Nachrichten

Frauen, die zum Zeitpunkt der Brustkrebsdiagnose eine hohe mammografische Brustdichte aufweisen, haben ein erhöhtes Risiko für ein baldiges Rezidiv, legen neue Daten nahe.

„Übersichtlicher Wegweiser“: Lauterbachs umstrittener Klinik-Atlas ist online

17.05.2024 Klinik aktuell Nachrichten

Sie sei „ethisch geboten“, meint Gesundheitsminister Karl Lauterbach: mehr Transparenz über die Qualität von Klinikbehandlungen. Um sie abzubilden, lässt er gegen den Widerstand vieler Länder einen virtuellen Klinik-Atlas freischalten.

Klinikreform soll zehntausende Menschenleben retten

15.05.2024 Klinik aktuell Nachrichten

Gesundheitsminister Lauterbach hat die vom Bundeskabinett beschlossene Klinikreform verteidigt. Kritik an den Plänen kommt vom Marburger Bund. Und in den Ländern wird über den Gang zum Vermittlungsausschuss spekuliert.

Darf man die Behandlung eines Neonazis ablehnen?

08.05.2024 Gesellschaft Nachrichten

In einer Leseranfrage in der Zeitschrift Journal of the American Academy of Dermatology möchte ein anonymer Dermatologe bzw. eine anonyme Dermatologin wissen, ob er oder sie einen Patienten behandeln muss, der eine rassistische Tätowierung trägt.

Update Radiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.