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01.03.2004 | Neonatal and Pediatric Intensive Care

Relation of cerebral tissue oxygenation index to central venous oxygen saturation in children

verfasst von: Nicole Nagdyman, Thilo Fleck, Sven Barth, Hashim Abdul-Khaliq, Brigitte Stiller, Peter Ewert, Michael Huebler, Hermann Kuppe, Peter E. Lange

Erschienen in: Intensive Care Medicine | Ausgabe 3/2004

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Abstract

Objective

To evaluate the relationship between the cerebral tissue oxygenation index measured by near-infrared spectroscopy and central venous oxygen saturation (SvO₂) after corrective surgery of congenital heart defects in children.

Design

Prospective observational clinical study.

Setting

A tertiary neonatal and paediatric intensive care unit for paediatric cardiology.

Patients

Neonates and children consecutively admitted to the paediatric cardiology intensive care unit after corrective surgery of non-cyanotic congenital heart defects.

Measurements and results

Forty-three children were studied. Cerebral tissue oxygenation index, measured non-invasively by near-infrared spectroscopy, was compared to SvO₂, measured by a catheter placed in the right atrium, and to haemodynamic and respiratory parameters. Pearson’s correlation coefficients and p values were calculated. Simultaneously measured values for SvO₂ (62.2±9.8%, 39.8–80.4%) and cerebral tissue oxygenation index (56.7±8.8%, 35.8–71.2%) showed a significant correlation (r=0.52, p<0.001).

Conclusion

Cerebral tissue oxygenation index and SvO₂ are not interchangeable parameters, but cerebral tissue oxygenation index reflects the haemodynamic influence on cerebral oxygenation after cardiovascular surgery. Further work is necessary to confirm the clinical role of continuous non-invasive measurement of cerebral tissue oxygenation index with regard to the variations of global systemic oxygen consumption after cardiac surgery in children.

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Titel: Relation of cerebral tissue oxygenation index to central venous oxygen saturation in children
verfasst von: Nicole Nagdyman
Thilo Fleck
Sven Barth
Hashim Abdul-Khaliq
Brigitte Stiller
Peter Ewert
Michael Huebler
Hermann Kuppe
Peter E. Lange
Publikationsdatum: 01.03.2004
Verlag: Springer-Verlag
Erschienen in: Intensive Care Medicine / Ausgabe 3/2004
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-003-2101-8

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Relation of cerebral tissue oxygenation index to central venous oxygen saturation in children