Skip to main content
Erschienen in: Intensive Care Medicine 1/2013

01.01.2013 | Original

Management of renal replacement therapy in ICU patients: an international survey

verfasst von: Matthieu Legrand, Michael Darmon, Michael Joannidis, Didier Payen

Erschienen in: Intensive Care Medicine | Ausgabe 1/2013

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The optimal management of renal replacement therapy (RRT) in critically ill patients remains a matter of debate, although insights have arisen from recent large trials. Nonetheless, little is known about the current practices and beliefs of intensivists. The goal of this study was to record current practices in RRT management among an international panel of intensivists.

Methods

An online questionnaire that included questions about RRT management in critically ill patients with acute kidney injury was sent to European Society of Intensive Care Medicine members in 2010.

Results

Two hundred and seventy-three intensivists from 50 countries responded. The respondents had an average of 12 (7–20) years of experience in ICUs, and most of them worked in mixed ICUs. Most of the intensivists were responsible for prescribing RRT (92.6 %). Half of the respondents reported using both intermittent haemodialysis and continuous renal replacement therapy techniques (CRRT), but most preferred using CRRT. The reasons for preferring CRRT were the perception of better haemodynamic stability, better therapeutic effect resulting from cytokine removal and easier fluid balance control. The intensivists used higher RRT doses in septic patients than in non-septic patients (p = 0.03). Finally, we observed an increasing inclination towards the early use of RRT among the intensivists.

Conclusion

CRRT remains the preferred technique for most intensivists in Europe, and a large proportion of the participating intensivists used RRT prescription doses similar to those proposed a decade ago. Our results provide insights into the motivations of intensivists while presenting the technique that may help in selecting control groups for future trials.
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Joannidis M, Forni LG (2011) Clinical review: timing of renal replacement therapy. Crit Care 15:223PubMedCrossRef Joannidis M, Forni LG (2011) Clinical review: timing of renal replacement therapy. Crit Care 15:223PubMedCrossRef
2.
Zurück zum Zitat RENAL Replacement Therapy Study Investigators, Bellomo R, Cass A, Cole L, Finfer S, Gallagher M, Lo S, McArthur C, McGuinness S, Myburgh J, Norton R, Scheinkestel C, Su S (2009) Intensity of continuous renal-replacement therapy in critically ill patients. N Engl J Med 361:1627–1638PubMedCrossRef RENAL Replacement Therapy Study Investigators, Bellomo R, Cass A, Cole L, Finfer S, Gallagher M, Lo S, McArthur C, McGuinness S, Myburgh J, Norton R, Scheinkestel C, Su S (2009) Intensity of continuous renal-replacement therapy in critically ill patients. N Engl J Med 361:1627–1638PubMedCrossRef
3.
Zurück zum Zitat VA/NIH Acute Renal Failure Trial Network, Palevsky PM, Zhang JH, O’Connor TZ, Chertow GM, Crowley ST, Choudhury D, Finkel K, Kellum JA, Paganini E, Schein RM, Smith MW, Swanson KM, Thompson BT, Vijayan A, Watnick S, Star RA, Peduzzi P (2008) Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med 359:7–20PubMedCrossRef VA/NIH Acute Renal Failure Trial Network, Palevsky PM, Zhang JH, O’Connor TZ, Chertow GM, Crowley ST, Choudhury D, Finkel K, Kellum JA, Paganini E, Schein RM, Smith MW, Swanson KM, Thompson BT, Vijayan A, Watnick S, Star RA, Peduzzi P (2008) Intensity of renal support in critically ill patients with acute kidney injury. N Engl J Med 359:7–20PubMedCrossRef
4.
Zurück zum Zitat Vinsonneau C, Camus C, Combes A, Costa de Beauregard MA, Klouche K, Boulain T, Pallot JL, Chiche JD, Taupin P, Landais P, Dhainaut JF, Hemodiafe Study Group (2006) Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial. Lancet 368:379–385PubMedCrossRef Vinsonneau C, Camus C, Combes A, Costa de Beauregard MA, Klouche K, Boulain T, Pallot JL, Chiche JD, Taupin P, Landais P, Dhainaut JF, Hemodiafe Study Group (2006) Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial. Lancet 368:379–385PubMedCrossRef
5.
Zurück zum Zitat Payen D, Mateo J, Cavaillon JM, Fraisse F, Floriot C, Vicaut E (2009) Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: a randomized controlled trial. Crit Care Med 37:803–810PubMedCrossRef Payen D, Mateo J, Cavaillon JM, Fraisse F, Floriot C, Vicaut E (2009) Impact of continuous venovenous hemofiltration on organ failure during the early phase of severe sepsis: a randomized controlled trial. Crit Care Med 37:803–810PubMedCrossRef
6.
Zurück zum Zitat Ricci Z, Ronco C (2011) Timing, dose and mode of dialysis in acute kidney injury. Curr Opin Crit Care 17:556–561PubMedCrossRef Ricci Z, Ronco C (2011) Timing, dose and mode of dialysis in acute kidney injury. Curr Opin Crit Care 17:556–561PubMedCrossRef
7.
Zurück zum Zitat Ronco C, Zanella M, Brendolan A, Milan M, Canato G, Zamperetti N, Bellomo R (2001) Management of severe acute renal failure in critically ill patients: an international survey in 345 centres. Nephrol Dial Transplant 16:230–237PubMedCrossRef Ronco C, Zanella M, Brendolan A, Milan M, Canato G, Zamperetti N, Bellomo R (2001) Management of severe acute renal failure in critically ill patients: an international survey in 345 centres. Nephrol Dial Transplant 16:230–237PubMedCrossRef
8.
Zurück zum Zitat Ricci Z, Ronco C, D’Amico G, De Felice R, Rossi S, Bolgan I, Bonello M, Zamperetti N, Petras D, Salvatori G, Dan M, Piccinni P (2006) Practice patterns in the management of acute renal failure in the critically ill patient: an international survey. Nephrol Dial Transplant 21:690–696PubMedCrossRef Ricci Z, Ronco C, D’Amico G, De Felice R, Rossi S, Bolgan I, Bonello M, Zamperetti N, Petras D, Salvatori G, Dan M, Piccinni P (2006) Practice patterns in the management of acute renal failure in the critically ill patient: an international survey. Nephrol Dial Transplant 21:690–696PubMedCrossRef
9.
Zurück zum Zitat Ricci Z, Picardo S, Ronco C (2007) Results from international questionnaires. Contrib Nephrol 156:297–303PubMedCrossRef Ricci Z, Picardo S, Ronco C (2007) Results from international questionnaires. Contrib Nephrol 156:297–303PubMedCrossRef
10.
Zurück zum Zitat Ronco C, Ricci Z, Bellomo R (2006) Current worldwide practice of dialysis dose prescription in acute renal failure. Curr Opin Crit Care 12:551–556PubMedCrossRef Ronco C, Ricci Z, Bellomo R (2006) Current worldwide practice of dialysis dose prescription in acute renal failure. Curr Opin Crit Care 12:551–556PubMedCrossRef
11.
Zurück zum Zitat Schiffl H, Lang SM, Fischer R (2002) Daily hemodialysis and the outcome of acute renal failure. N Engl J Med 346:305–310PubMedCrossRef Schiffl H, Lang SM, Fischer R (2002) Daily hemodialysis and the outcome of acute renal failure. N Engl J Med 346:305–310PubMedCrossRef
12.
Zurück zum Zitat Ronco C, Bellomo R, Homel P, Brendolan A, Dan M, Piccinni P, La Greca G (2000) Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial. Lancet 356:26–30PubMedCrossRef Ronco C, Bellomo R, Homel P, Brendolan A, Dan M, Piccinni P, La Greca G (2000) Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial. Lancet 356:26–30PubMedCrossRef
13.
Zurück zum Zitat Saudan P, Niederberger M, De Seigneux S, Romand J, Pugin J, Perneger T, Martin PY (2006) Adding a dialysis dose to continuous hemofiltration increases survival in patients with acute renal failure. Kidney Int 70:1312–1317PubMedCrossRef Saudan P, Niederberger M, De Seigneux S, Romand J, Pugin J, Perneger T, Martin PY (2006) Adding a dialysis dose to continuous hemofiltration increases survival in patients with acute renal failure. Kidney Int 70:1312–1317PubMedCrossRef
14.
Zurück zum Zitat Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C, Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators, (2005) Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294:813–818PubMedCrossRef Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C, Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators, (2005) Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294:813–818PubMedCrossRef
15.
Zurück zum Zitat Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Oudemans-van Straaten H, Ronco C, Kellum JA (2007) Continuous renal replacement therapy: a worldwide practice survey. The beginning and ending supportive therapy for the kidney (BEST kidney) investigators. Intensive Care Med 33:1563–1570PubMedCrossRef Uchino S, Bellomo R, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Oudemans-van Straaten H, Ronco C, Kellum JA (2007) Continuous renal replacement therapy: a worldwide practice survey. The beginning and ending supportive therapy for the kidney (BEST kidney) investigators. Intensive Care Med 33:1563–1570PubMedCrossRef
16.
Zurück zum Zitat Lins RL, Elseviers MM, Van der Niepen P, Hoste E, Malbrain ML, Damas P, Devriendt J, SHARF investigators, (2009) Intermittent versus continuous renal replacement therapy for acute kidney injury patients admitted to the intensive care unit: results of a randomized clinical trial. Nephrol Dial Transplant 24:512–518PubMedCrossRef Lins RL, Elseviers MM, Van der Niepen P, Hoste E, Malbrain ML, Damas P, Devriendt J, SHARF investigators, (2009) Intermittent versus continuous renal replacement therapy for acute kidney injury patients admitted to the intensive care unit: results of a randomized clinical trial. Nephrol Dial Transplant 24:512–518PubMedCrossRef
17.
Zurück zum Zitat Schortgen F, Soubrier N, Delclaux C, Thuong M, Girou E, Brun-Buisson C, Lemaire F, Brochard L (2000) Hemodynamic tolerance of intermittent hemodialysis in critically ill patients: usefulness of practice guidelines. Am J Respir Crit Care Med 162:197–202PubMed Schortgen F, Soubrier N, Delclaux C, Thuong M, Girou E, Brun-Buisson C, Lemaire F, Brochard L (2000) Hemodynamic tolerance of intermittent hemodialysis in critically ill patients: usefulness of practice guidelines. Am J Respir Crit Care Med 162:197–202PubMed
18.
Zurück zum Zitat Angus DC, Mira J-P, Vincent J-L (2010) Improving clinical trials in the critically ill. Crit Care Med 38:527–532PubMedCrossRef Angus DC, Mira J-P, Vincent J-L (2010) Improving clinical trials in the critically ill. Crit Care Med 38:527–532PubMedCrossRef
19.
Zurück zum Zitat Bell M, Granath F, Schön S, Ekbom A, Martling C-R (2007) Continuous renal replacement therapy is associated with less chronic renal failure than intermittent haemodialysis after acute renal failure. Intensive Care Med 33:773–780PubMedCrossRef Bell M, Granath F, Schön S, Ekbom A, Martling C-R (2007) Continuous renal replacement therapy is associated with less chronic renal failure than intermittent haemodialysis after acute renal failure. Intensive Care Med 33:773–780PubMedCrossRef
20.
Zurück zum Zitat Cole L, Bellomo R, Hart G, Journois D, Davenport P, Tipping P, Ronco C (2002) A phase II randomized, controlled trial of continuous hemofiltration in sepsis. Crit Care Med 30:100–106PubMedCrossRef Cole L, Bellomo R, Hart G, Journois D, Davenport P, Tipping P, Ronco C (2002) A phase II randomized, controlled trial of continuous hemofiltration in sepsis. Crit Care Med 30:100–106PubMedCrossRef
21.
Zurück zum Zitat Joannidis M (2009) Continuous renal replacement therapy in sepsis and multisystem organ failure. Semin Dial 2:160–164CrossRef Joannidis M (2009) Continuous renal replacement therapy in sepsis and multisystem organ failure. Semin Dial 2:160–164CrossRef
22.
Zurück zum Zitat Lombel RM, Kommareddi M, Mottes T, Selewski DT, Han YY, Gipson DS, Collins KL, Heung M (2012) Implications of different fluid overload definitions in pediatric stem cell transplant patients requiring continuous renal replacement therapy. Intensive Care Med 38:663–669PubMedCrossRef Lombel RM, Kommareddi M, Mottes T, Selewski DT, Han YY, Gipson DS, Collins KL, Heung M (2012) Implications of different fluid overload definitions in pediatric stem cell transplant patients requiring continuous renal replacement therapy. Intensive Care Med 38:663–669PubMedCrossRef
23.
Zurück zum Zitat Karvellas CJ, Farhat MR, Sajjad I, Mogensen SS, Leung AA, Wald R, Bagshaw SM (2011) A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis. Crit Care 15:R72PubMedCrossRef Karvellas CJ, Farhat MR, Sajjad I, Mogensen SS, Leung AA, Wald R, Bagshaw SM (2011) A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis. Crit Care 15:R72PubMedCrossRef
24.
Zurück zum Zitat Csomos A, Varga S, Bertolini G, Hibbert C, Sandor J, Capuzzo M, Guidet BR (2010) Intensive care reimbursement practices: results from the ICUFUND survey. Intensive Care Med 36:1759–1764PubMedCrossRef Csomos A, Varga S, Bertolini G, Hibbert C, Sandor J, Capuzzo M, Guidet BR (2010) Intensive care reimbursement practices: results from the ICUFUND survey. Intensive Care Med 36:1759–1764PubMedCrossRef
25.
Zurück zum Zitat Cannesson M, Pestel G, Ricks C, Hoeft A, Perel A (2011) Crit Care Hemodynamic monitoring and management in patients undergoing high risk surgery: a survey among north American and European anesthesiologists. Crit Care 15:R197PubMedCrossRef Cannesson M, Pestel G, Ricks C, Hoeft A, Perel A (2011) Crit Care Hemodynamic monitoring and management in patients undergoing high risk surgery: a survey among north American and European anesthesiologists. Crit Care 15:R197PubMedCrossRef
26.
Zurück zum Zitat Beloucif S, Payen D (1998) A European survey of the use of inhaled nitric oxide in the ICU. Working group on inhaled NO in the ICU of the European Society of Intensive Care Medicine. Intensive Care Med 24:864–877PubMedCrossRef Beloucif S, Payen D (1998) A European survey of the use of inhaled nitric oxide in the ICU. Working group on inhaled NO in the ICU of the European Society of Intensive Care Medicine. Intensive Care Med 24:864–877PubMedCrossRef
Metadaten
Titel
Management of renal replacement therapy in ICU patients: an international survey
verfasst von
Matthieu Legrand
Michael Darmon
Michael Joannidis
Didier Payen
Publikationsdatum
01.01.2013
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 1/2013
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-012-2706-x

Weitere Artikel der Ausgabe 1/2013

Intensive Care Medicine 1/2013 Zur Ausgabe

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Hinter dieser Appendizitis steckte ein Erreger

23.04.2024 Appendizitis Nachrichten

Schmerzen im Unterbauch, aber sonst nicht viel, was auf eine Appendizitis hindeutete: Ein junger Mann hatte Glück, dass trotzdem eine Laparoskopie mit Appendektomie durchgeführt und der Wurmfortsatz histologisch untersucht wurde.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.