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24.02.2017 | Editorial

Intensive care medicine in 2050: precision medicine

Erschienen in: Intensive Care Medicine | Ausgabe 10/2017

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By 2050, intensive care medicine will evolve from reliance on treatment protocols, guidelines, consensus definitions, and organ support to regularly applying the principles of precision medicine. Precision medicine entails the customization of therapies based on unique features of an individual patient or of patient subtypes. At a fundamental level, we already practice precision medicine. For example, among patients with cardiovascular shock, we select different pharmacologic agents on the basis of the etiology of shock. However, the hope is that the field can evolve toward a more granular form of precision medicine, wherein we directly address the unique molecular and biological features of an individual patient. For example, the rapidly evolving discipline of pharmacogenomics provides an opportunity to tailor drug selection and dosing based on genetic variants modifying drug response and metabolism [1]. …

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Titel: Intensive care medicine in 2050: precision medicine
Publikationsdatum: 24.02.2017
Erschienen in: Intensive Care Medicine / Ausgabe 10/2017
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-017-4727-y

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Intensive care medicine in 2050: precision medicine

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