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Intensive Care Medicine

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25.11.2020 | COVID-19 | Editorial Zur Zeit gratis

Is severe COVID-19 pneumonia a typical or atypical form of ARDS? And does it matter?

verfasst von: Ewan C. Goligher, V. Marco Ranieri, Arthur S. Slutsky

Erschienen in: Intensive Care Medicine | Ausgabe 1/2021

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Excerpt

The coronavirus disease 2019 (COVID-19) pandemic has proven remarkable for many reasons, among them its capacity to provoke controversy and debate. One hotly debated question is whether severe COVID-19 pneumonia should be classified simply as another cause of acute respiratory distress syndrome (ARDS), or as a particular subtype of ARDS with pathophysiological features so unique that a different approach to ventilatory management is needed. Does severe COVID-19 pneumonia fall within the usual pathophysiological spectrum of ARDS or is it a qualitatively different disease state? And what consequences might the answer to this question hold for the optimal ventilatory management of severe COVID-19? …

Chiumello D, Busana M, Coppola S et al (2020) Physiological and quantitative CT-scan characterization of COVID-19 and typical ARDS: a matched cohort study. Intensive Care Med. https://doi.org/10.1007/s00134-020-06281-2CrossRefPubMedPubMedCentral

Dantzker DR, Brook CJ, Dehart P, Lynch JP, Weg JG (1979) Ventilation-perfusion distributions in the adult respiratory distress syndrome. Am Rev Respir Dis 120:1039PubMed

Pensier J, de Jong A, Hajjej Z et al (2019) Effect of lung recruitment maneuver on oxygenation, physiological parameters and mortality in acute respiratory distress syndrome patients: a systematic review and meta-analysis. Intensive Care Med 45:1691–1702. https://doi.org/10.1007/s00134-019-05821-9CrossRefPubMed

Patel BV, Arachchillage DJ, Ridge CA et al (2020) Pulmonary angiopathy in severe COVID-19: physiologic, imaging, and hematologic observations. Am J Respir Crit Care Med 202:690–699. https://doi.org/10.1164/rccm.202004-1412OCCrossRefPubMedPubMedCentral

Ackermann M, Verleden SE, Kuehnel M et al (2020) Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in Covid-19. New Eng J Med. https://doi.org/10.1056/NEJMoa2015432CrossRefPubMed

Herrmann J, Mori V, Bates JHT, Suki B (2020) Modeling lung perfusion abnormalities to explain early COVID-19 hypoxemia. Nat Commun 11:4883. https://doi.org/10.1038/s41467-020-18672-6CrossRefPubMedPubMedCentral

Cummings MJ, Baldwin MR, Abrams D et al (2020) Epidemiology, clinical course, and outcomes of critically ill adults with COVID-19 in New York City: a prospective cohort study. The Lancet (British edition) 395:1763–1770. https://doi.org/10.1016/S0140-6736(20)31189-2CrossRef

Schenck EJ, Hoffman K, Goyal P et al (2020) Respiratory mechanics and gas exchange in COVID-19 associated respiratory failure. Ann Am Thora Soc 17:1158–1161. https://doi.org/10.1513/AnnalsATS.202005-427RLCrossRef

Ferrando C, Suarez-Sipmann F, Mellado-Artigas R et al (2020) Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS. Intensive Care Med. https://doi.org/10.1007/s00134-020-06192-2CrossRefPubMedPubMedCentral

10.

Grasselli G, Tonetti T, Protti A et al (2020) Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study. Lancet Resp Med. https://doi.org/10.1016/S2213-2600(20)30370-2CrossRef

11.

Botta M, Tsonas AM, Pillay J et al (2020) Ventilation management and clinical outcome in invasively ventilated COVID–19 patients (PRoVENT–COVID) – a national, multicentre, observational cohort study. Lancet Resp Med. https://doi.org/10.1016/S2213-8CrossRef

12.

Panwar R, Madotto F, Laffey JG, Van Haren FMP (2020) Compliance phenotypes in early ARDS before the COVID-19 pandemic. Am J Respir Crit Care Med. https://doi.org/10.1164/rccm.202005-2046OCCrossRefPubMedPubMedCentral

13.

Horie S, McNicholas B, Rezoagli E et al (2020) Emerging pharmacological therapies for ARDS: COVID-19 and beyond. Intensive Care Med. https://doi.org/10.1007/s00134-020-06141-zCrossRefPubMedPubMedCentral

14.

Mauri T, Spinelli E, Scotti E et al (2020) Potential for lung recruitment and ventilation-perfusion mismatch in patients with the acute respiratory distress syndrome from coronavirus disease 2019. Crit Care Med 48:1129–1134. https://doi.org/10.1097/CCM.0000000000004386CrossRefPubMedPubMedCentral

15.

Pan C, Chen L, Lu C et al (2020) Lung Recruitability in COVID-19-associated acute respiratory distress syndrome: a single-center observational study. Am J Respir Crit Care Med 201:1294–1297. https://doi.org/10.1164/rccm.202003-0527LECrossRefPubMedPubMedCentral

16.

Turbil E, Terzi N, Cour M, Argaud L, Einav S, Guérin C (2020) Positive end-expiratory pressure-induced recruited lung volume measured by volume-pressure curves in acute respiratory distress syndrome: a physiologic systematic review and meta-analysis. Intensive Care Med. https://doi.org/10.1007/s00134-020-06226-9CrossRefPubMedPubMedCentral

17.

Sinha P, Delucchi KL, Thompson BT, McAuley DF, Matthay MA, Calfee CS (2018) Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study. Intensive Care Med 44:1859–1869. https://doi.org/10.1007/s00134-018-5378-3CrossRefPubMedPubMedCentral

18.

Vincent J, Slutsky AS (2020) We have never seen a patient with ARDS. Intensive care Med. https://doi.org/10.1007/s00134-020-06255-4CrossRefPubMedPubMedCentral

19.

Goligher EC, Kavanagh BP, Rubenfeld GD et al (2014) Oxygenation response to positive end-expiratory pressure predicts mortality in acute respiratory distress syndrome. A secondary analysis of the LOVS and ExPress trials. Am J Respir Crit Care Med 190:70–76. https://doi.org/10.1164/rccm.201404-0688OC[doi]CrossRefPubMed

20.

Chen L, Del Sorbo L, Grieco DL et al (2020) Potential for lung recruitment estimated by the recruitment-to-inflation ratio in acute respiratory distress syndrome. Clin Am J Respir Crit Care Med 201:178–187. https://doi.org/10.1164/rccm.201902-0334ocCrossRef

Titel: Is severe COVID-19 pneumonia a typical or atypical form of ARDS? And does it matter?
verfasst von: Ewan C. Goligher
V. Marco Ranieri
Arthur S. Slutsky
Publikationsdatum: 25.11.2020
Verlag: Springer Berlin Heidelberg
Schlagwort: COVID-19
Erschienen in: Intensive Care Medicine / Ausgabe 1/2021
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-020-06320-y

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Is severe COVID-19 pneumonia a typical or atypical form of ARDS? And does it matter?

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