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01.04.2010 | Cardiac

Towards risk stratification in systemic atherosclerosis: value of myocardial function and viability imaging as an adjunct to MR angiography

verfasst von: Achim Seeger, Michael Fenchel, Ulrich Kramer, Christiane Bretschneider, Florian Grimm, Bernhard Klumpp, Albertus Scheule, Bernd Balletshofer, Claus D. Claussen, Stephan Miller

Erschienen in: European Radiology | Ausgabe 4/2010

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Abstract

Objectives

To longitudinally assess the value of cardiac functional and viability imaging as a supplement to MR angiography in patients with atherosclerotic disease.

Methods

Cardiac MRI was performed in 195 consecutive patients with symptomatic peripheral arterial disease. Of these, 186 patients were followed for 22 ± 5 months for the presence of cardiac events (cardiac death, acute coronary syndrome and hospitalisation as a result of congestive heart failure).

Results

Myocardial viability imaging showed a high prevalence of known (n = 31) and occult myocardial infarctions (MI) (n = 26). Cardiac events occurred more often in patients with reduced ventricular function (ejection fraction (EF) less than 40%, cardiac event in 4/8 patients; EF 40–55%, cardiac event in 10/40 patients; EF greater than 55%, cardiac event in 15/138 patients) as well as in patients with occult MI (8/25 patients) and known MI (11/30 patients). In patients with normal function, the detection of a previous MI was of high relevance to prognosis.

Conclusions

Both reduced EF and the presence of MI influence patients’ prognoses. Performing cardiac MRI in this patient population may influence further patient management including intensified risk factor intervention.

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Titel: Towards risk stratification in systemic atherosclerosis: value of myocardial function and viability imaging as an adjunct to MR angiography
verfasst von: Achim Seeger
Michael Fenchel
Ulrich Kramer
Christiane Bretschneider
Florian Grimm
Bernhard Klumpp
Albertus Scheule
Bernd Balletshofer
Claus D. Claussen
Stephan Miller
Publikationsdatum: 01.04.2010
Verlag: Springer-Verlag
Erschienen in: European Radiology / Ausgabe 4/2010
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-009-1607-z

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Towards risk stratification in systemic atherosclerosis: value of myocardial function and viability imaging as an adjunct to MR angiography