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European Radiology
Erschienen in: European Radiology 1/2015

01.01.2015 | Oncology

Efficacy and safety of radiofrequency ablation for treating locoregional recurrence from papillary thyroid cancer

verfasst von: Hyun Kyung Lim, Jung Hwan Baek, Jeong Hyun Lee, Won Bae Kim, Tae Yong Kim, Young Kee Shong, Suck Joon Hong

Erschienen in: European Radiology | Ausgabe 1/2015

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Abstract

Objectives

To assess the efficacy and safety of ultrasound- (US) guided radiofrequency ablation (RFA) for controlling locoregional recurrent papillary thyroid cancer (PTC) in a large patient population.

Methods

We included patients who had undergone RFA for locoregional recurrent PTC between September 2008 and April 2012 who fulfilled the following criteria: no metastasis beyond the neck; not more than four tumours; confirmed recurrence by US-guided fine needle aspiration biopsy or thyroglobulin measurement of needle washouts; more than a six-month follow-up period; and surgery not feasible or was refused by the patient.

Results

Sixty-one recurrent tumours in 39 patients were included. The mean follow-up duration was 26.4 ± 13.7 months. Tumour volume decreased significantly from 0.20 ± 0.35 ml before ablation to 0.02 ± 0.11 ml (P < .001), with a mean volume reduction ratio of 95.1 ± 12.3 %. Fifty tumours (82.0 %) completely disappeared. Eleven tumours were visible at last follow-up US. The mean serum thyroglobulin level decreased from 1.21 ± 1.91 to 0.50 ± 0.80 ng/ml (P = .001). The overall complication rate was 7.7 % (3/39).

Conclusions

RFA can effectively control locoregional recurrent PTC without life-threatening complications; therefore, RFA may replace “berry picking surgery” in selected patients.

Key Points

• RFA for recurrent PTC achieved a volume reduction ratio of 95.1 ± 12.3 %
• Eighty-two percent (50/61) of recurrent PTC completely disappeared after RFA
• The mean serum thyroglobulin level decreased significantly (P = .001) after RFA
• RFA may replace “berry picking surgery” for recurrent PTC
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Metadaten
Titel
Efficacy and safety of radiofrequency ablation for treating locoregional recurrence from papillary thyroid cancer
verfasst von
Hyun Kyung Lim
Jung Hwan Baek
Jeong Hyun Lee
Won Bae Kim
Tae Yong Kim
Young Kee Shong
Suck Joon Hong
Publikationsdatum
01.01.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 1/2015
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3405-5

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