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15.09.2015 | Magnetic Resonance

Accelerated magnetic resonance diffusion tensor imaging of the median nerve using simultaneous multi-slice echo planar imaging with blipped CAIPIRINHA

verfasst von: Lukas Filli, Marco Piccirelli, David Kenkel, Andreas Boss, Andrei Manoliu, Gustav Andreisek, Himanshu Bhat, Val M. Runge, Roman Guggenberger

Erschienen in: European Radiology | Ausgabe 6/2016

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Abstract

Purpose

To investigate the feasibility of MR diffusion tensor imaging (DTI) of the median nerve using simultaneous multi-slice echo planar imaging (EPI) with blipped CAIPIRINHA.

Materials and methods

After federal ethics board approval, MR imaging of the median nerves of eight healthy volunteers (mean age, 29.4 years; range, 25–32) was performed at 3 T using a 16-channel hand/wrist coil. An EPI sequence (b-value, 1,000 s/mm²; 20 gradient directions) was acquired without acceleration as well as with twofold and threefold slice acceleration. Fractional anisotropy (FA), mean diffusivity (MD) and quality of nerve tractography (number of tracks, average track length, track homogeneity, anatomical accuracy) were compared between the acquisitions using multivariate ANOVA and the Kruskal-Wallis test.

Results

Acquisition time was 6:08 min for standard DTI, 3:38 min for twofold and 2:31 min for threefold acceleration. No differences were found regarding FA (standard DTI: 0.620 ± 0.058; twofold acceleration: 0.642 ± 0.058; threefold acceleration: 0.644 ± 0.061; p ≥ 0.217) and MD (standard DTI: 1.076 ± 0.080 mm²/s; twofold acceleration: 1.016 ± 0.123 mm²/s; threefold acceleration: 0.979 ± 0.153 mm²/s; p ≥ 0.074). Twofold acceleration yielded similar tractography quality compared to standard DTI (p > 0.05). With threefold acceleration, however, average track length and track homogeneity decreased (p = 0.004–0.021).

Conclusion

Accelerated DTI of the median nerve is feasible. Twofold acceleration yields similar results to standard DTI.

Key Points

• Standard DTI of the median nerve is limited by its long acquisition time.

• Simultaneous multi-slice acquisition is a new technique for accelerated DTI.

• Accelerated DTI of the median nerve yields similar results to standard DTI.

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Titel: Accelerated magnetic resonance diffusion tensor imaging of the median nerve using simultaneous multi-slice echo planar imaging with blipped CAIPIRINHA
verfasst von: Lukas Filli
Marco Piccirelli
David Kenkel
Andreas Boss
Andrei Manoliu
Gustav Andreisek
Himanshu Bhat
Val M. Runge
Roman Guggenberger
Publikationsdatum: 15.09.2015
Verlag: Springer Berlin Heidelberg
Erschienen in: European Radiology / Ausgabe 6/2016
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-015-3985-8

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Accelerated magnetic resonance diffusion tensor imaging of the median nerve using simultaneous multi-slice echo planar imaging with blipped CAIPIRINHA