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Erschienen in:
10.04.2021 | Review
Karydakis procedure versus Limberg flap for treatment of pilonidal sinus: an updated meta-analysis of randomized controlled trials
Erschienen in: International Journal of Colorectal Disease | Ausgabe 7/2021
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Background
The Karydakis procedure (KP) and Limberg flap (LF) are two commonly performed operations for pilonidal sinus disease (PND). The present meta-analysis aimed to review the outcome of randomized trials that compared KP and LF.
Methods
Electronic databases were searched in a systematic manner for randomized trials comparing KP and LF through July 2020. This meta-analysis was reported in line with the PRISMA statement. The main outcome measures were failure of healing of PND, complications, time to healing, time to return to work, and cosmetic satisfaction.
Results
Fifteen randomized controlled trials (1943 patients) were included. KP had a significantly shorter operation time than LF with a weighted mean difference (WMD) of −0.788 (95%CI: −11.55 to −4.21, p < 0.0001). Pain scores, hospital stay, and time to healing were similar. There was no significant difference in overall complications (OR= 1.61, 95%CI: 0.9–2.85, p = 0.11) and failure of healing (OR= 1.22, 95%CI: 0.76–1.95, p = 0.41). KP had higher odds of wound infection (OR= 1.87, 95%CI: 1.15–3.04, p = 0.011) and seroma formation (OR= 2.33, 95%CI: 1.39–3.9, p = 0.001). KP was followed by a shorter time to return to work (WMD= −0.182; 95%CI: −3.58 to −0.066, p = 0.04) and a higher satisfaction score than LF (WMD= 2.81, 95%CI: 0.65–3.77, p = 0.01).
Conclusions
KP and LF were followed by similar rates of complications and failure of healing of PND and comparable stay, pain scores, and time to wound healing. KP was associated with higher rates of seroma and wound infection, shorter time to return to work, and higher cosmetic satisfaction than LF.