Erschienen in:
01.10.2017 | SPECIAL CONTRIBUTION
Joint SNMMI–ASNC expert consensus document on the role of 18F-FDG PET/CT in cardiac sarcoid detection and therapy monitoring
verfasst von:
Panithaya Chareonthaitawee, Rob S. Beanlands, Wengen Chen, Sharmila Dorbala, Edward J. Miller, Venkatesh L. Murthy, David H. Birnie, Edward S. Chen, Leslie T. Cooper, Roderick H. Tung, Eric S. White, Salvador Borges-Neto, Marcelo F. Di Carli, Robert J. Gropler, Terrence D. Ruddy, Thomas H. Schindler, Ron Blankstein
Erschienen in:
Journal of Nuclear Cardiology
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Ausgabe 5/2017
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Excerpt
Sarcoidosis is a systemic disorder of unknown etiology whose clinical presentation is characterized by the heterogeneous contributions of nonnecrotizing granulomatous inflammation and concomitant fibrosis. Cardiac involvement portends an adverse prognosis and may account for approximately 25% of deaths from sarcoidosis. The diagnosis of cardiac sarcoidosis (CS) remains a challenge because of the combination of a nonspecific clinical presentation (e.g., conduction abnormalities, tachy- and bradyarrhythmias, and heart failure) and focal infiltration of granulomas and scarring in the heart, which limit the diagnostic utility of endomyocardial biopsy (EMB). Potentiating these challenges is the fact that data on the benefit of immunosuppressive therapy are limited. …