Skip to main content
Erschienen in: World Journal of Surgery 3/2012

01.03.2012

Long-term Results with the Modified Sugiura Procedure for the Management of Variceal Bleeding: Standing the Test of Time in the Treatment of Bleeding Esophageal Varices

verfasst von: D. Voros, A. Polydorou, G. Polymeneas, I. Vassiliou, A. Melemeni, K. Chondrogiannis, V. Arapoglou, G. P. Fragulidis

Erschienen in: World Journal of Surgery | Ausgabe 3/2012

Einloggen, um Zugang zu erhalten

Abstract

Background

The surgical approaches to the treatment of bleeding esophageal varices in cirrhotic patients have been reduced since the clinical development of endoscopic sclerotherapy, transjugular intrahepatic portosystemic shunt (TIPS), and liver transplantation. However, when acute sclerotherapy fails, and in cases where no further treatment is accessible, emergency surgery may be life saving. In the present study we retrospectively analyzed the results of the modified Sugiura procedure, performed as emergency and semi-elective treatment in the patient with bleeding esophageal varices.

Methods

Ninety patients with cirrhosis and portal hypertension were managed in our department for variceal esophageal bleeding between January 1985 and December 1992. The modified Sugiura procedure was performed in 46 patients on an emergency (25 patients) or semi-elective (21 patients) basis. Liver cirrhosis stage according to Child classification was A in 4 patients, B in 16 patients, and C in 26 patients.

Results

Acute bleeding was controlled in all patients. Postoperative mortality was 23.9% (11 of 46 patients). The mortality rate was 34.6% in Child class C patients (9 of 26 patients), and 12.5% in Child class B patients (2 of 16 patients). Twenty-four patients had long-term follow-up extending from 14 months to 22 years (mean 83.1 months). Ten of 24 patients (41.6%) did not develop rebleeding for 5–22 years (mean 10.3 years). Overall 5-year survival in these 24 patients was 62.5%.

Conclusions

The modified Sugiura procedure remains an effective rescue therapy for patients with bleeding esophageal varices when alternative treatments fail or are not indicated. Moreover, it can be a life-saving procedure in patients with anatomy unsuitable for shunt surgery or for patients treated in nonspecialized centers where surgical expertise for a shunt operation is not available.
Literatur
1.
Zurück zum Zitat Wolff M, Hirner A (2003) Current state of portosystemic shunt surgery. Langenbecks Arch Surg 388:141–149PubMedCrossRef Wolff M, Hirner A (2003) Current state of portosystemic shunt surgery. Langenbecks Arch Surg 388:141–149PubMedCrossRef
2.
Zurück zum Zitat Bosch J, Berzigotti A, Garcia-Pagan JC et al (2008) The management of portal hypertension: rational basis, available treatments and future options. J Hepatol 48(Suppl 1):S68–S92PubMedCrossRef Bosch J, Berzigotti A, Garcia-Pagan JC et al (2008) The management of portal hypertension: rational basis, available treatments and future options. J Hepatol 48(Suppl 1):S68–S92PubMedCrossRef
3.
Zurück zum Zitat Rosemurgy AS, Zervos EE (2003) Management of variceal hemorrhage. Curr Probl Surg 40:263–343PubMedCrossRef Rosemurgy AS, Zervos EE (2003) Management of variceal hemorrhage. Curr Probl Surg 40:263–343PubMedCrossRef
4.
Zurück zum Zitat Wright AS, Rikkers LF (2005) Current management of portal hypertension. J Gastrointest Surg 9:992–1005PubMedCrossRef Wright AS, Rikkers LF (2005) Current management of portal hypertension. J Gastrointest Surg 9:992–1005PubMedCrossRef
5.
Zurück zum Zitat Burroughs AK, Vangeli M (2002) Transjugular intrahepatic portosystemic shunt versus endoscopic therapy: randomized trials for secondary prophylaxis of variceal bleeding: an updated meta-analysis. Scand J Gastroenterol 37:249–252PubMedCrossRef Burroughs AK, Vangeli M (2002) Transjugular intrahepatic portosystemic shunt versus endoscopic therapy: randomized trials for secondary prophylaxis of variceal bleeding: an updated meta-analysis. Scand J Gastroenterol 37:249–252PubMedCrossRef
6.
Zurück zum Zitat Selzner M, Tuttle-Newhall JE et al (2001) Current indication of a modified Sugiura procedure in the management of variceal bleeding. J Am Coll Surg 193:166–173PubMedCrossRef Selzner M, Tuttle-Newhall JE et al (2001) Current indication of a modified Sugiura procedure in the management of variceal bleeding. J Am Coll Surg 193:166–173PubMedCrossRef
7.
Zurück zum Zitat Dagenais M, Langer B, Taylor BR et al (1994) Experience with radical esophagogastric devascularization procedures (Sugiura) for variceal bleeding outside Japan. World J Surg 18:222–228. doi:10.1007/BF00294405 PubMedCrossRef Dagenais M, Langer B, Taylor BR et al (1994) Experience with radical esophagogastric devascularization procedures (Sugiura) for variceal bleeding outside Japan. World J Surg 18:222–228. doi:10.​1007/​BF00294405 PubMedCrossRef
8.
Zurück zum Zitat Voros D, Androulakis G, Mallas E et al (1993) Immediate results of operations for esophageal varices. Hell J Gastroenterol 6:261–266 Voros D, Androulakis G, Mallas E et al (1993) Immediate results of operations for esophageal varices. Hell J Gastroenterol 6:261–266
9.
Zurück zum Zitat Voros D, Karapanos K, Kyriazi M et al (2007) Long-term outcome of a modified Sugiura procedure for bleeding esophageal varices. ISW 2007 conference abstract ID: 113 Voros D, Karapanos K, Kyriazi M et al (2007) Long-term outcome of a modified Sugiura procedure for bleeding esophageal varices. ISW 2007 conference abstract ID: 113
10.
Zurück zum Zitat Grace ND (1992) Prevention of initial variceal hemorrhage. Gastroenterol Clin N Am 21:149–161 Grace ND (1992) Prevention of initial variceal hemorrhage. Gastroenterol Clin N Am 21:149–161
11.
Zurück zum Zitat Stanley AJ, Hayes PC (1997) Portal hypertension and variceal haemorrhage. Lancet 350:1235–1239PubMedCrossRef Stanley AJ, Hayes PC (1997) Portal hypertension and variceal haemorrhage. Lancet 350:1235–1239PubMedCrossRef
12.
Zurück zum Zitat Burnett DA, Rikkers LF (1990) Nonoperative emergency treatment of variceal hemorrhage. Surg Clin N Am 70:291–306PubMed Burnett DA, Rikkers LF (1990) Nonoperative emergency treatment of variceal hemorrhage. Surg Clin N Am 70:291–306PubMed
13.
Zurück zum Zitat D’Amico G, Pagliaro L, Bosch J (1995) The treatment of portal hypertension: a meta-analytic review. Hepatology 22:332–354PubMed D’Amico G, Pagliaro L, Bosch J (1995) The treatment of portal hypertension: a meta-analytic review. Hepatology 22:332–354PubMed
14.
Zurück zum Zitat de Franchis R, Primignani M (1999) Endoscopic treatments for portal hypertension. Semin Liver Dis 19:439–455PubMedCrossRef de Franchis R, Primignani M (1999) Endoscopic treatments for portal hypertension. Semin Liver Dis 19:439–455PubMedCrossRef
15.
Zurück zum Zitat Henderson JM, Nagle A, Curtas S et al (2000) Surgical shunts and TIPS for variceal decompression in the 1990 s. Surgery 128:540–547PubMedCrossRef Henderson JM, Nagle A, Curtas S et al (2000) Surgical shunts and TIPS for variceal decompression in the 1990 s. Surgery 128:540–547PubMedCrossRef
17.
Zurück zum Zitat Orozco H, Juarez F, Uribe M et al (1986) Sugiura procedure outside Japan. The Mexican experience. Am J Surg 152:539–542PubMedCrossRef Orozco H, Juarez F, Uribe M et al (1986) Sugiura procedure outside Japan. The Mexican experience. Am J Surg 152:539–542PubMedCrossRef
18.
Zurück zum Zitat Gouge TH, Ranson JH (1986) Esophageal transection and paraesophagogastric devascularization for bleeding esophageal varices. Am J Surg 151:47–54PubMedCrossRef Gouge TH, Ranson JH (1986) Esophageal transection and paraesophagogastric devascularization for bleeding esophageal varices. Am J Surg 151:47–54PubMedCrossRef
19.
Zurück zum Zitat Mercado MA, Orozco H, Vasquez M et al (1998) Comparative study of 2 variants of a modified esophageal transection in the Sugiura–Futagawa operation. Arch Surg 133:1046–1049PubMedCrossRef Mercado MA, Orozco H, Vasquez M et al (1998) Comparative study of 2 variants of a modified esophageal transection in the Sugiura–Futagawa operation. Arch Surg 133:1046–1049PubMedCrossRef
20.
Zurück zum Zitat Jin G, Rikkers LF (1996) Transabdominal esophagogastric devascularization as treatment for variceal hemorrhage. Surgery 120:641–647 (discussion 647–649)PubMedCrossRef Jin G, Rikkers LF (1996) Transabdominal esophagogastric devascularization as treatment for variceal hemorrhage. Surgery 120:641–647 (discussion 647–649)PubMedCrossRef
21.
Zurück zum Zitat Walker RM (1964) Esophageal transection for bleeding varices. Surg Gynecol Obstet 118:323PubMed Walker RM (1964) Esophageal transection for bleeding varices. Surg Gynecol Obstet 118:323PubMed
22.
Zurück zum Zitat Johnston GW (1977) Treatment of bleeding varices by oesophageal transection with the SPTU gun. Ann R Coll Surg Engl 59:404–408PubMed Johnston GW (1977) Treatment of bleeding varices by oesophageal transection with the SPTU gun. Ann R Coll Surg Engl 59:404–408PubMed
23.
Zurück zum Zitat Burroughs AK, Hamilton G, Phillips A et al (1989) A comparison of sclerotherapy with staple transection of the esophagus for the emergency control of bleeding from esophageal varices. N Engl J Med 321:857–862PubMedCrossRef Burroughs AK, Hamilton G, Phillips A et al (1989) A comparison of sclerotherapy with staple transection of the esophagus for the emergency control of bleeding from esophageal varices. N Engl J Med 321:857–862PubMedCrossRef
24.
25.
Zurück zum Zitat Sugiura M, Futagawa S (1984) Esophageal transection with paraesophagogastric devascularizations (the Sugiura procedure) in the treatment of esophageal varices. World J Surg 673–679. doi:10.1007/BF01655762 Sugiura M, Futagawa S (1984) Esophageal transection with paraesophagogastric devascularizations (the Sugiura procedure) in the treatment of esophageal varices. World J Surg 673–679. doi:10.​1007/​BF01655762
26.
Zurück zum Zitat Barbot DJ, Rosato EF (1987) Experience with the esophagogastric devascularization procedure. Surgery 101:685–690PubMed Barbot DJ, Rosato EF (1987) Experience with the esophagogastric devascularization procedure. Surgery 101:685–690PubMed
27.
Zurück zum Zitat Weese JL, Starling JR, Yale CE (1984) Control of bleeding esophageal varices by transabdominal esophageal transection, gastric devascularization, and splenectomy. Surg Gastroenterol 3:31–36PubMed Weese JL, Starling JR, Yale CE (1984) Control of bleeding esophageal varices by transabdominal esophageal transection, gastric devascularization, and splenectomy. Surg Gastroenterol 3:31–36PubMed
28.
Zurück zum Zitat Ginsberg RJ, Waters PF, Zeldin RA et al (1982) A modified Sugiura procedure. Ann Thorac Surg 34:258–264PubMedCrossRef Ginsberg RJ, Waters PF, Zeldin RA et al (1982) A modified Sugiura procedure. Ann Thorac Surg 34:258–264PubMedCrossRef
29.
Zurück zum Zitat Cello JP, Crass R, Trunkey DD (1982) Endoscopic sclerotherapy versus esophageal transection of Child class C patients with variceal hemorrhage. Comparison with results of portacaval shunt: preliminary report. Surgery 91:333–338PubMed Cello JP, Crass R, Trunkey DD (1982) Endoscopic sclerotherapy versus esophageal transection of Child class C patients with variceal hemorrhage. Comparison with results of portacaval shunt: preliminary report. Surgery 91:333–338PubMed
30.
Zurück zum Zitat Hosking SW, Johnson AG (1987) What happens to esophageal varices after transection and devascularization? Surgery 101:531–534PubMed Hosking SW, Johnson AG (1987) What happens to esophageal varices after transection and devascularization? Surgery 101:531–534PubMed
31.
Zurück zum Zitat Qazi SA, Khalid K, Hameed AM et al (2006) Transabdominal gastro-esophageal devascularization and esophageal transection for bleeding esophageal varices after failed injection sclerotherapy: long-term follow-up report. World J Surg 30:1329–1337. doi:10.1007/s00268-005-0372-7 PubMedCrossRef Qazi SA, Khalid K, Hameed AM et al (2006) Transabdominal gastro-esophageal devascularization and esophageal transection for bleeding esophageal varices after failed injection sclerotherapy: long-term follow-up report. World J Surg 30:1329–1337. doi:10.​1007/​s00268-005-0372-7 PubMedCrossRef
32.
Zurück zum Zitat Spence RAJ, Johnston GW (1985) Results in 100 consecutive patients with stapled esophageal transaction for varices. Surg Gynecol Obstet 160:323–329PubMed Spence RAJ, Johnston GW (1985) Results in 100 consecutive patients with stapled esophageal transaction for varices. Surg Gynecol Obstet 160:323–329PubMed
33.
Zurück zum Zitat Langer BF, Greig PD, Taylor BR (1990) Emergency surgical treatment of variceal hemorrhage. Surg Clin N Am 70:307–311PubMed Langer BF, Greig PD, Taylor BR (1990) Emergency surgical treatment of variceal hemorrhage. Surg Clin N Am 70:307–311PubMed
34.
Zurück zum Zitat Koyanagi N, Iso Y, Higashi H et al (1988) Recurrence of varices after oesophageal transection: intra-operative and postoperative assessment by endoscopy. Br J Surg 75:9–11PubMedCrossRef Koyanagi N, Iso Y, Higashi H et al (1988) Recurrence of varices after oesophageal transection: intra-operative and postoperative assessment by endoscopy. Br J Surg 75:9–11PubMedCrossRef
35.
Zurück zum Zitat Johnson M, Rajendran S, Balachandar TG et al (2006) Transabdominal modified devascularization procedure with or without esophageal stapler transaction—an operation adequate for effective control of a variceal bleed. Is esophageal stapler transection necessary? World J Surg 30:1507–1518. doi:10.1007/s00268-005-0754-x (discussion 1519)PubMedCrossRef Johnson M, Rajendran S, Balachandar TG et al (2006) Transabdominal modified devascularization procedure with or without esophageal stapler transaction—an operation adequate for effective control of a variceal bleed. Is esophageal stapler transection necessary? World J Surg 30:1507–1518. doi:10.​1007/​s00268-005-0754-x (discussion 1519)PubMedCrossRef
36.
Zurück zum Zitat Comar KM, Sanyal AJ (2003) Portal hypertensive bleeding. Gastroenterol Clin N Am 32:1079–1105CrossRef Comar KM, Sanyal AJ (2003) Portal hypertensive bleeding. Gastroenterol Clin N Am 32:1079–1105CrossRef
37.
Zurück zum Zitat Idezuki Y, Sanjyo K (1989) Twenty-five-year experiences with esophageal transection for esophageal varices. J Thorac Cardiovasc Surg 98:876–883PubMed Idezuki Y, Sanjyo K (1989) Twenty-five-year experiences with esophageal transection for esophageal varices. J Thorac Cardiovasc Surg 98:876–883PubMed
38.
Zurück zum Zitat Mathur SK, Shah SR, Soonawala ZF et al (1997) Transabdominal extensive oesophagogastric devascularization with gastro-oesophageal stapling in the management of acute variceal bleeding. Br J Surg 84:413–417PubMedCrossRef Mathur SK, Shah SR, Soonawala ZF et al (1997) Transabdominal extensive oesophagogastric devascularization with gastro-oesophageal stapling in the management of acute variceal bleeding. Br J Surg 84:413–417PubMedCrossRef
39.
Zurück zum Zitat Goyal N, Singhal D, Gupta S et al (2007) Transabdominal gastroesophageal devascularization without transection for bleeding varices: results and indicators of prognosis. J Gastroenterol Hepatol 22:47–50PubMedCrossRef Goyal N, Singhal D, Gupta S et al (2007) Transabdominal gastroesophageal devascularization without transection for bleeding varices: results and indicators of prognosis. J Gastroenterol Hepatol 22:47–50PubMedCrossRef
40.
Zurück zum Zitat Chaudhary A, Aranya RC (1991) Devascularization following endoscopic sclerotherapy of oesophageal varices: dangers and difficulties. Br J Surg 78:1249–1251PubMedCrossRef Chaudhary A, Aranya RC (1991) Devascularization following endoscopic sclerotherapy of oesophageal varices: dangers and difficulties. Br J Surg 78:1249–1251PubMedCrossRef
41.
Zurück zum Zitat Klempnaue J, Schrem H (2001) Review: surgical shunts and encephalopathy. Metab Brain Dis 16:21–25PubMedCrossRef Klempnaue J, Schrem H (2001) Review: surgical shunts and encephalopathy. Metab Brain Dis 16:21–25PubMedCrossRef
42.
Zurück zum Zitat Chalasani N, Clark WS, Martin LG et al (2000) Determinants of mortality in patients with advanced cirrhosis after transjugular intrahepatic portosystemic shunting. Gastroenterology 118:138–144PubMedCrossRef Chalasani N, Clark WS, Martin LG et al (2000) Determinants of mortality in patients with advanced cirrhosis after transjugular intrahepatic portosystemic shunting. Gastroenterology 118:138–144PubMedCrossRef
43.
Zurück zum Zitat LaBerge JM, Sombers KA, Lake JR et al (1995) Two-year outcome following transjugular intrahepatic portosystemic shunt for variceal bleeding: results in 90 patients. Gastroenterology 108:1143–1151PubMedCrossRef LaBerge JM, Sombers KA, Lake JR et al (1995) Two-year outcome following transjugular intrahepatic portosystemic shunt for variceal bleeding: results in 90 patients. Gastroenterology 108:1143–1151PubMedCrossRef
45.
Zurück zum Zitat Sanyal AJ, Freedman AM, Luketic VA et al (1996) Transjugular intrahepatic portosystemic shunts for patients with active variceal hemorrhage unresponsive to sclerotherapy. Gastroenterology 111:138–146PubMedCrossRef Sanyal AJ, Freedman AM, Luketic VA et al (1996) Transjugular intrahepatic portosystemic shunts for patients with active variceal hemorrhage unresponsive to sclerotherapy. Gastroenterology 111:138–146PubMedCrossRef
46.
Zurück zum Zitat Orloff MJ, Isenberg JI, Wheeler HO et al (2010) Liver transplantation in a randomized controlled trial of emergency treatment of acutely bleeding esophageal varices in cirrhosis. Transplant Proc 42:4101–4108PubMedCrossRef Orloff MJ, Isenberg JI, Wheeler HO et al (2010) Liver transplantation in a randomized controlled trial of emergency treatment of acutely bleeding esophageal varices in cirrhosis. Transplant Proc 42:4101–4108PubMedCrossRef
47.
Zurück zum Zitat Terblanche J (2002) The management of portal hypertension: controversies. J Gastroenterol Hepatol 17(Suppl):S439–S440PubMedCrossRef Terblanche J (2002) The management of portal hypertension: controversies. J Gastroenterol Hepatol 17(Suppl):S439–S440PubMedCrossRef
Metadaten
Titel
Long-term Results with the Modified Sugiura Procedure for the Management of Variceal Bleeding: Standing the Test of Time in the Treatment of Bleeding Esophageal Varices
verfasst von
D. Voros
A. Polydorou
G. Polymeneas
I. Vassiliou
A. Melemeni
K. Chondrogiannis
V. Arapoglou
G. P. Fragulidis
Publikationsdatum
01.03.2012
Verlag
Springer-Verlag
Erschienen in
World Journal of Surgery / Ausgabe 3/2012
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-011-1418-7

Weitere Artikel der Ausgabe 3/2012

World Journal of Surgery 3/2012 Zur Ausgabe

Vorsicht, erhöhte Blutungsgefahr nach PCI!

10.05.2024 Koronare Herzerkrankung Nachrichten

Nach PCI besteht ein erhöhtes Blutungsrisiko, wenn die Behandelten eine verminderte linksventrikuläre Ejektionsfraktion aufweisen. Das Risiko ist umso höher, je stärker die Pumpfunktion eingeschränkt ist.

Darf man die Behandlung eines Neonazis ablehnen?

08.05.2024 Gesellschaft Nachrichten

In einer Leseranfrage in der Zeitschrift Journal of the American Academy of Dermatology möchte ein anonymer Dermatologe bzw. eine anonyme Dermatologin wissen, ob er oder sie einen Patienten behandeln muss, der eine rassistische Tätowierung trägt.

Deutlich weniger Infektionen: Wundprotektoren schützen!

08.05.2024 Postoperative Wundinfektion Nachrichten

Der Einsatz von Wundprotektoren bei offenen Eingriffen am unteren Gastrointestinaltrakt schützt vor Infektionen im Op.-Gebiet – und dient darüber hinaus der besseren Sicht. Das bestätigt mit großer Robustheit eine randomisierte Studie im Fachblatt JAMA Surgery.

Chirurginnen und Chirurgen sind stark suizidgefährdet

07.05.2024 Suizid Nachrichten

Der belastende Arbeitsalltag wirkt sich negativ auf die psychische Gesundheit der Angehörigen ärztlicher Berufsgruppen aus. Chirurginnen und Chirurgen bilden da keine Ausnahme, im Gegenteil.

Update Chirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

S3-Leitlinie „Diagnostik und Therapie des Karpaltunnelsyndroms“

Karpaltunnelsyndrom BDC Leitlinien Webinare
CME: 2 Punkte

Das Karpaltunnelsyndrom ist die häufigste Kompressionsneuropathie peripherer Nerven. Obwohl die Anamnese mit dem nächtlichen Einschlafen der Hand (Brachialgia parästhetica nocturna) sehr typisch ist, ist eine klinisch-neurologische Untersuchung und Elektroneurografie in manchen Fällen auch eine Neurosonografie erforderlich. Im Anfangsstadium sind konservative Maßnahmen (Handgelenksschiene, Ergotherapie) empfehlenswert. Bei nicht Ansprechen der konservativen Therapie oder Auftreten von neurologischen Ausfällen ist eine Dekompression des N. medianus am Karpaltunnel indiziert.

Prof. Dr. med. Gregor Antoniadis
Berufsverband der Deutschen Chirurgie e.V.

S2e-Leitlinie „Distale Radiusfraktur“

Radiusfraktur BDC Leitlinien Webinare
CME: 2 Punkte

Das Webinar beschäftigt sich mit Fragen und Antworten zu Diagnostik und Klassifikation sowie Möglichkeiten des Ausschlusses von Zusatzverletzungen. Die Referenten erläutern, welche Frakturen konservativ behandelt werden können und wie. Das Webinar beantwortet die Frage nach aktuellen operativen Therapiekonzepten: Welcher Zugang, welches Osteosynthesematerial? Auf was muss bei der Nachbehandlung der distalen Radiusfraktur geachtet werden?

PD Dr. med. Oliver Pieske
Dr. med. Benjamin Meyknecht
Berufsverband der Deutschen Chirurgie e.V.

S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“

Appendizitis BDC Leitlinien Webinare
CME: 2 Punkte

Inhalte des Webinars zur S1-Leitlinie „Empfehlungen zur Therapie der akuten Appendizitis bei Erwachsenen“ sind die Darstellung des Projektes und des Erstellungswegs zur S1-Leitlinie, die Erläuterung der klinischen Relevanz der Klassifikation EAES 2015, die wissenschaftliche Begründung der wichtigsten Empfehlungen und die Darstellung stadiengerechter Therapieoptionen.

Dr. med. Mihailo Andric
Berufsverband der Deutschen Chirurgie e.V.