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Intensive Care Medicine
Erschienen in: Intensive Care Medicine 12/2008

01.12.2008 | Original

Measurement of end-expiratory lung volume by oxygen washin–washout in controlled and assisted mechanically ventilated patients

verfasst von: N. Patroniti, M. Saini, A. Zanella, D. Weismann, S. Isgrò, G. Bellani, G. Foti, A. Pesenti

Erschienen in: Intensive Care Medicine | Ausgabe 12/2008

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Abstract

Objective

Assessing limits of agreement with helium dilution and repeatability of a new system (lung funcution, LUFU) that measures end-expiratory lung volume (EELV) in mechanically ventilated patients using the O2 washin (EELVWin) and washout (EELVWout) technique. LUFU consists of an Evita 4 ventilator, a side-stream oxygen analyzer, and a dedicated PC software.

Design and setting

Prospective human study in a general ICU of a University hospital.

Patients

Thirty-six mechanically ventilated patients.

Interventions

We obtained 36 couples of both EELVWin and EELVWout measurements in each patient (5 with healthy lungs, 9 with ALI, 22 with ARDS). Measurements were obtained with patients ventilated either by assisted (ASB, 16 measurements) or controlled (CMV, 20 measurements) ventilation. In 19 of 20 cases in CMV, we obtained helium dilution measurements (EELVHe).

Measurements and results

Bias for agreement with EELVHe was −16 ± 156 and 8 ± 161 ml, respectively, for EELVWin and EELVWout. Bias for agreement between EELVWin and EELVWout was 28 ± 78 and 23 ± 168 ml, respectively, for CMV and ASB. During CMV bias for repeatability were 8 ± 92 and 23 ± 165 ml, respectively, for EELVWin and EELVWout. During ASB bias for repeatability were 32 ± 160 and −15 ± 147 ml, respectively, for EELVWin and EELVWout.

Conclusions

The LUFU method showed good agreement with helium, and good repeatability during partial and controlled mechanical ventilation. The technique is simple and safe.
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Metadaten
Titel
Measurement of end-expiratory lung volume by oxygen washin–washout in controlled and assisted mechanically ventilated patients
verfasst von
N. Patroniti
M. Saini
A. Zanella
D. Weismann
S. Isgrò
G. Bellani
G. Foti
A. Pesenti
Publikationsdatum
01.12.2008
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 12/2008
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-008-1218-1

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