Erschienen in:
01.10.2006 | Pediatric Correspondence
Mechanical ventilation with heliox decreases respiratory system resistance and facilitates CO2 removal in obstructive airway disease
verfasst von:
Martin C. J. Kneyber, Marc van Heerde, Dick G. Markhorst, Frans B. Plötz
Erschienen in:
Intensive Care Medicine
|
Ausgabe 10/2006
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Excerpt
Sir: Helium has a density that is one-seventh that of air, resulting in a decreased resistance to gas flow allowing for increased bulk and oxygen flow. Additionally, CO
2 diffuses through helium much easier than through air [
1,
2]. The beneficial effect of heliox on lowering the respiratory system resistance (R
rs) has been demonstrated in a pediatric porcine model of obstructive airway disease (OAD) [
3]. However, the effect of heliox on R
rs and CO
2 diffusion in a mechanically ventilated infant with OAD and refractory hypercapnia has not reported before. …