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International Journal of Computer Assisted Radiology and Surgery

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01.07.2014 | Original Article

MRI-compatible positioning device for guiding a focused ultrasound system for transrectal treatment of prostate cancer

verfasst von: Christos Yiallouras, Nicos Mylonas, Christakis Damianou

Erschienen in: International Journal of Computer Assisted Radiology and Surgery | Ausgabe 4/2014

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Abstract

Background

High-intensity focused ultrasound (HIFU) is a promising treatment method for many common cancers, including prostate cancer. Magnetic resonance image (MRI) guidance of HIFU permits targeting and monitoring of therapy. A prototype MRI-compatible positioning device that navigates a HIFU transducer was designed, fabricated and tested.

Materials and methods

The positioning device has two PC-controlled and one manually driven stage that allow endorectal access to the prostate. The positioning device was constructed using a 3-D rapid prototype manufacturing device. Software was developed that controls the motion of the positioning device and enables activation of a HIFU transducer. In vitro testing of the system was performed in a 1.5T MRI scanner using ex vivo turkey tissue. Optical encoders were employed to enhance the accuracy of this positioning device.

Result

The positioning device was successfully tested for MRI compatibility. The movement error of the positioning device is approximately 20 \(\upmu \)m. The robot has the ability to accurately move the transducer for creation of discrete and overlapping lesions.

Conclusion

An MRI-compatible HIFU positioning system was developed that has the ability to create thermal lesions with MRI guidance for endorectal treatment of prostate cancer.

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Titel: MRI-compatible positioning device for guiding a focused ultrasound system for transrectal treatment of prostate cancer
verfasst von: Christos Yiallouras
Nicos Mylonas
Christakis Damianou
Publikationsdatum: 01.07.2014
Verlag: Springer Berlin Heidelberg
Erschienen in: International Journal of Computer Assisted Radiology and Surgery / Ausgabe 4/2014
Print ISSN: 1861-6410
Elektronische ISSN: 1861-6429
DOI: https://doi.org/10.1007/s11548-013-0964-x

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Springer Medizin

MRI-compatible positioning device for guiding a focused ultrasound system for transrectal treatment of prostate cancer

Abstract

Background

Materials and methods

Result

Conclusion

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Abstract

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Materials and methods

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Conclusion

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