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Erschienen in: Skeletal Radiology 1/2021

16.07.2020 | Scientific Article

Patients with ACL graft deficiency showed a higher frequency of knee osteoarthritis compared with patients with intact ACL graft in the medium term

verfasst von: Ozan Asmakutlu, Deniz Alis, Cagdas Topel, Mujdat Bankaoglu

Erschienen in: Skeletal Radiology | Ausgabe 1/2021

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Abstract

Aim

To evaluate whether patients with anterior cruciate ligament (ACL) graft tear who do not undergo revision reconstruction surgery are more likely to exhibit osteoarthritic features than patients with intact ACL graft using MRI.

Materials and methods

We retrospectively evaluated our hospital medical archive for identifying all consecutive patients with ACL graft failure who underwent MRI between January 2015 and January 2019. An equal number of patients with intact ACL graft was selected for the control group. An observer with 6 years of musculoskeletal radiology experience evaluated the baseline and last available follow-up MRIs of the patients for bone marrow lesions (BMLs), cartilage defects, osteophytes, anterior tibial translation, and effusion-synovitis.

Results

A total of 130 patients, 118 males (90.8%), and 12 females (9.2%), with the mean age of 29.22 ± 9.3 years, were enrolled in the study. Of 130 patients, 65 had a deficient ACL graft, and 65 had an intact ACL graft. The time from the index injury to the last follow-up MRI was 45 months (IQR, 19) for the study cohort. On the follow-up MRIs, patients with ACL graft deficiency showed more prominent degenerative features compared with the patients with intact ACL graft characterized as follows: higher grades of medial meniscal tears (P = 0.06); higher grades of BMLs in the anteromedial (P = 0.014) and posteromedial (P = 0.006) femur, higher grades of cartilage defects in the medial patella (p = 0.0P); higher grades of osteophytes in the anteromedial (P = 0.018) and central medial femur (p = 0.048), central medial tibia (P = 0.048), and medial patella (P = 0.07); and more frequent anterior tibial translation (P = 0.022).

Conclusion

Patients with ACL graft deficiency present with more prominent degenerative features, particularly on the medial side, suggestive of osteoarthritis compared with patients with intact ACL grafts in the medium-term follow-up.
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Literatur
1.
Zurück zum Zitat Griffin LY, Agel J, Albohm MJ, et al. Noncontact anterior cruciate ligament injuries: risk factors and prevention strategies. J Am Acad Orthop Surg. 2000;8:141–50.CrossRef Griffin LY, Agel J, Albohm MJ, et al. Noncontact anterior cruciate ligament injuries: risk factors and prevention strategies. J Am Acad Orthop Surg. 2000;8:141–50.CrossRef
2.
Zurück zum Zitat Mall NA, Chalmers PN, Moric M, et al. Incidence and trends of anterior cruciate ligament reconstruction in the United States. Am J Sports Med. 2014;42:2363–237.CrossRef Mall NA, Chalmers PN, Moric M, et al. Incidence and trends of anterior cruciate ligament reconstruction in the United States. Am J Sports Med. 2014;42:2363–237.CrossRef
3.
Zurück zum Zitat Csintalan RP, Inacio MC, Funahashi TT, et al. Incidence rate of anterior cruciate ligament reconstructions. Perm J. 2008;12:3.CrossRef Csintalan RP, Inacio MC, Funahashi TT, et al. Incidence rate of anterior cruciate ligament reconstructions. Perm J. 2008;12:3.CrossRef
4.
Zurück zum Zitat Oiestad BE, Engebretsen L, Storheim K, Risberg MA. Knee osteoarthritis after anterior cruciate ligament injury: a systematic review. Am J Sports Med. 2009;37(7):1434e43.CrossRef Oiestad BE, Engebretsen L, Storheim K, Risberg MA. Knee osteoarthritis after anterior cruciate ligament injury: a systematic review. Am J Sports Med. 2009;37(7):1434e43.CrossRef
5.
Zurück zum Zitat Gillquist J, Messner K. Anterior cruciate ligament reconstruction and the long-term incidence of gonarthrosis. Sports Med. 1999;27(3):143e56.CrossRef Gillquist J, Messner K. Anterior cruciate ligament reconstruction and the long-term incidence of gonarthrosis. Sports Med. 1999;27(3):143e56.CrossRef
6.
Zurück zum Zitat Mizuta H, Kubota K, Shiraishi M, et al. The conservative treatment of complete tears of the anterior cruciate ligament in skeletally immature patients. J Bone Joint Surg (Br). 1995;77-B:890–4.CrossRef Mizuta H, Kubota K, Shiraishi M, et al. The conservative treatment of complete tears of the anterior cruciate ligament in skeletally immature patients. J Bone Joint Surg (Br). 1995;77-B:890–4.CrossRef
7.
Zurück zum Zitat Kessler MA, Behrend H, Henz S, Stutz G, Rukavina A, Kuster MS. Function, osteoarthritis and activity after ACL-rupture: 11 years follow-up results of conservative versus reconstructive treatment. Knee Surg Sports Traumatol Arthrosc. 2008;16:442–8.CrossRef Kessler MA, Behrend H, Henz S, Stutz G, Rukavina A, Kuster MS. Function, osteoarthritis and activity after ACL-rupture: 11 years follow-up results of conservative versus reconstructive treatment. Knee Surg Sports Traumatol Arthrosc. 2008;16:442–8.CrossRef
8.
Zurück zum Zitat Frobell RB, Roos EM, Roos HP, Ranstam J, Lohmander LS. A randomized trial of treatment for acute anterior cruciate ligament tears. N Engl J Med. 2010;363:331–42.CrossRef Frobell RB, Roos EM, Roos HP, Ranstam J, Lohmander LS. A randomized trial of treatment for acute anterior cruciate ligament tears. N Engl J Med. 2010;363:331–42.CrossRef
9.
Zurück zum Zitat Frobell RB, Roos HP, Roos EM, et al. Treatment for acute anterior cruciate ligament tear: five year outcome of randomised trial. BMJ. 2013;346:F232.CrossRef Frobell RB, Roos HP, Roos EM, et al. Treatment for acute anterior cruciate ligament tear: five year outcome of randomised trial. BMJ. 2013;346:F232.CrossRef
10.
Zurück zum Zitat Lohmander LS, Englund PM, Dahl LL, Roos EM. The long-term consequence of ACL and meniscus injuries: osteoarthritis. Am J Sports Med. 2007;35(10):1756–69.CrossRef Lohmander LS, Englund PM, Dahl LL, Roos EM. The long-term consequence of ACL and meniscus injuries: osteoarthritis. Am J Sports Med. 2007;35(10):1756–69.CrossRef
11.
Zurück zum Zitat George MS, Dunn WR, Spindler KP. Current concepts review: revision anterior cruciate ligament reconstruction. Am J Sports Med. 2006;34(12):2026–37.CrossRef George MS, Dunn WR, Spindler KP. Current concepts review: revision anterior cruciate ligament reconstruction. Am J Sports Med. 2006;34(12):2026–37.CrossRef
12.
Zurück zum Zitat Hettrich CM, Dunn WR, Reinke EK, Spindler KP; MOON Group. The rate of subsequent surgery and predictors after anterior cruciate ligament reconstruction: two- and 6-year follow-up results from a multicenter cohort. Am J Sports Med 2013;41(7):1534–1540. Hettrich CM, Dunn WR, Reinke EK, Spindler KP; MOON Group. The rate of subsequent surgery and predictors after anterior cruciate ligament reconstruction: two- and 6-year follow-up results from a multicenter cohort. Am J Sports Med 2013;41(7):1534–1540.
13.
Zurück zum Zitat Leiter JR, Gourlay R, McRae S, de Korompay N, MacDonald PB. Long-term follow-up of ACL reconstruction with hamstring autograft. Knee Surg Sports Traumatol Arthrosc. 2014;22(5):1061–9.PubMed Leiter JR, Gourlay R, McRae S, de Korompay N, MacDonald PB. Long-term follow-up of ACL reconstruction with hamstring autograft. Knee Surg Sports Traumatol Arthrosc. 2014;22(5):1061–9.PubMed
14.
Zurück zum Zitat Wright RW, Magnussen RA, Dunn WR, Spindler KP. Ipsilateral graft and contralateral ACL rupture at five years or more following ACL reconstruction: a systematic review. J Bone Joint Surg Am. 2011;93(12):1159–65.CrossRef Wright RW, Magnussen RA, Dunn WR, Spindler KP. Ipsilateral graft and contralateral ACL rupture at five years or more following ACL reconstruction: a systematic review. J Bone Joint Surg Am. 2011;93(12):1159–65.CrossRef
15.
16.
17.
Zurück zum Zitat Saupe N, White LM, Chiavaras MM, et al. Anterior cruciate ligament reconstruction grafts: MR imaging features at long-term follow-up correlation with functional and clinical evaluation. Radiology. 2008;249:581–90.CrossRef Saupe N, White LM, Chiavaras MM, et al. Anterior cruciate ligament reconstruction grafts: MR imaging features at long-term follow-up correlation with functional and clinical evaluation. Radiology. 2008;249:581–90.CrossRef
18.
Zurück zum Zitat Wang B, Lee KT. Results of revision anterior cruciate ligament reconstruction using a transportal technique. Acta Orthop Belg. 2015;81(4):752–8.PubMed Wang B, Lee KT. Results of revision anterior cruciate ligament reconstruction using a transportal technique. Acta Orthop Belg. 2015;81(4):752–8.PubMed
19.
Zurück zum Zitat MARS Group. Effect of graft choice on the outcome of revision anterior cruciate ligament reconstruction in the Multicenter ACL Revision Study (MARS) Cohort. Am J Sports Med. 2014;42(10):2301–10.CrossRef MARS Group. Effect of graft choice on the outcome of revision anterior cruciate ligament reconstruction in the Multicenter ACL Revision Study (MARS) Cohort. Am J Sports Med. 2014;42(10):2301–10.CrossRef
20.
Zurück zum Zitat Chahal J, Lee A, Heard W, Bach BR Jr. A retrospective review of anterior cruciate ligament reconstruction using patellar tendon: 25 years of experience. Orthop J Sports Med. 2013;1(3):2325967113501789.CrossRef Chahal J, Lee A, Heard W, Bach BR Jr. A retrospective review of anterior cruciate ligament reconstruction using patellar tendon: 25 years of experience. Orthop J Sports Med. 2013;1(3):2325967113501789.CrossRef
21.
Zurück zum Zitat Roemer FW, Frobell R, Lohmander LS, Niu J, Guermazi A. Anterior Cruciate Ligament Osteoarthritis Score (ACLOAS): longitudinal MRI-based whole joint assessment of anterior cruciate ligament injury. Osteoarthr Cartil. 2014;22(5):668–82.CrossRef Roemer FW, Frobell R, Lohmander LS, Niu J, Guermazi A. Anterior Cruciate Ligament Osteoarthritis Score (ACLOAS): longitudinal MRI-based whole joint assessment of anterior cruciate ligament injury. Osteoarthr Cartil. 2014;22(5):668–82.CrossRef
22.
Zurück zum Zitat Chiu SS. The anterior tibial translocation sign. Radiology. 2006;239(3):914–5.CrossRef Chiu SS. The anterior tibial translocation sign. Radiology. 2006;239(3):914–5.CrossRef
25.
Zurück zum Zitat Fernandez-Madrid F, Karvonen RL, Teitge RA, Miller PR, An T, Negendank WG. Synovial thickening detected by MR imaging in osteoarthritis of the knee confirmed by biopsy as synovitis. Magn Reson Imaging. 1995;13:177e83.CrossRef Fernandez-Madrid F, Karvonen RL, Teitge RA, Miller PR, An T, Negendank WG. Synovial thickening detected by MR imaging in osteoarthritis of the knee confirmed by biopsy as synovitis. Magn Reson Imaging. 1995;13:177e83.CrossRef
26.
Zurück zum Zitat Altman DG. Practical statistics for medical research. 1st ed. New York: Chapman & Hall/CRC Press; 1991. Altman DG. Practical statistics for medical research. 1st ed. New York: Chapman & Hall/CRC Press; 1991.
27.
Zurück zum Zitat Culvenor AG, Collins NJ, Guermazi A, et al. Early knee osteoarthritis is evident one year following anterior cruciate ligament reconstruction: a magnetic resonance imaging evaluation. Arthritis Rheumatol. 2015;67(4):946–55.CrossRef Culvenor AG, Collins NJ, Guermazi A, et al. Early knee osteoarthritis is evident one year following anterior cruciate ligament reconstruction: a magnetic resonance imaging evaluation. Arthritis Rheumatol. 2015;67(4):946–55.CrossRef
28.
Zurück zum Zitat Sharma L, Lou C, Cahue S, Dunlop DD. The mechanism of the effect of obesity in knee osteoarthritis: the mediating role of malalignment. Arthritis Rheum. 2000;43(3):568–75.CrossRef Sharma L, Lou C, Cahue S, Dunlop DD. The mechanism of the effect of obesity in knee osteoarthritis: the mediating role of malalignment. Arthritis Rheum. 2000;43(3):568–75.CrossRef
29.
Zurück zum Zitat Magnussen RA, Mansour AA, Carey JL, Spindler KP. Meniscus status at anterior cruciate ligament reconstruction associated with radiographic signs of osteoarthritis at 5- to 10-year follow-up: a systematic review. J Knee Surg. 2009;22:347e57.CrossRef Magnussen RA, Mansour AA, Carey JL, Spindler KP. Meniscus status at anterior cruciate ligament reconstruction associated with radiographic signs of osteoarthritis at 5- to 10-year follow-up: a systematic review. J Knee Surg. 2009;22:347e57.CrossRef
30.
Zurück zum Zitat Stein V, Li L, Lo G, et al. Pattern of joint damage in persons with knee osteoarthritis and concomitant ACL tears. Rheumatol Int. 2012;32(5):1197–208.CrossRef Stein V, Li L, Lo G, et al. Pattern of joint damage in persons with knee osteoarthritis and concomitant ACL tears. Rheumatol Int. 2012;32(5):1197–208.CrossRef
31.
Zurück zum Zitat Sward P, Kostogiannis I, Neuman P, Von Porat A, Boegard T, Roos H. Differences in the radiological characteristics between post- traumatic and non-traumatic knee osteoarthritis. Scand J Med Sci Sports. 2010;20(5):731–9.CrossRef Sward P, Kostogiannis I, Neuman P, Von Porat A, Boegard T, Roos H. Differences in the radiological characteristics between post- traumatic and non-traumatic knee osteoarthritis. Scand J Med Sci Sports. 2010;20(5):731–9.CrossRef
32.
Zurück zum Zitat Cicuttini FM, Forbes A, Yuanyuan W, Rush G, Stuckey SL. Rate of knee cartilage loss after partial meniscectomy. J Rheumatol. 2002;29(9):1954e6. Cicuttini FM, Forbes A, Yuanyuan W, Rush G, Stuckey SL. Rate of knee cartilage loss after partial meniscectomy. J Rheumatol. 2002;29(9):1954e6.
Metadaten
Titel
Patients with ACL graft deficiency showed a higher frequency of knee osteoarthritis compared with patients with intact ACL graft in the medium term
verfasst von
Ozan Asmakutlu
Deniz Alis
Cagdas Topel
Mujdat Bankaoglu
Publikationsdatum
16.07.2020
Verlag
Springer Berlin Heidelberg
Erschienen in
Skeletal Radiology / Ausgabe 1/2021
Print ISSN: 0364-2348
Elektronische ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-020-03549-y

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