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01.04.2005 | Weiterbildung · Zertifizierte Fortbildung

Postoperative Strahlentherapie beim invasiven Mammakarzinom

verfasst von: PD Dr. R. Souchon, G. Ansorge, J. Dunst

Erschienen in: Die Onkologie | Ausgabe 4/2005

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Zusammenfassung

Die Strahlentherapie ist wichtiger Bestandteil des kurativ ausgerichteten, üblicherweise multimodalen Therapiekonzepts nach operativer Primärbehandlung beim lokal begrenzten Mammakarzinom. Ihr Stellenwert wurde auf der Basis aktueller Ergebnisse prospektiver und randomisierter Studien und somit auf hohem Evidenzniveau präzisiert. Die Radiotherapie nach Brust erhaltender Operation ist unverzichtbar für die prognostisch entscheidende lokale Tumorkontrolle als wichtigstem Therapieziel. Sie verbessert diese sowie das Überleben. Therapiesequenz und mögliche Interaktionen der Radiotherapie mit neuen systemischen, potenziell kardiotoxischen Behandlungen sind klinisch wichtige, aktuell diskutierte Fragestellungen. Die radiogene Kardiotoxizität kann beim Einsatz heutiger Bestrahlungstechniken als gering angesehen werden. Daten über eventuelle adverse kardiologische Interaktionen von diesen Substanzen bei kombiniertem Einsatz mit der perkutanen Radiotherapie liegen allerdings nur in begrenztem Umfang vor.

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Titel: Postoperative Strahlentherapie beim invasiven Mammakarzinom
verfasst von: PD Dr. R. Souchon
G. Ansorge
J. Dunst
Publikationsdatum: 01.04.2005
Verlag: Springer-Verlag
Erschienen in: Die Onkologie / Ausgabe 4/2005
Print ISSN: 2731-7226
Elektronische ISSN: 2731-7234
DOI: https://doi.org/10.1007/s00761-005-0861-1

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