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Magnetic Resonance Materials in Physics, Biology and Medicine

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02.01.2019 | Research Article

Precision of T1-relaxation time measurements in the hepatic portal vein: influence of measurement technique and sequence parameters

verfasst von: Svein Are Sirirud Vatnehol, Per Kristian Hol, Atle Bjørnerud, Mahmood Amiry-Moghaddam, Camilla Haglerød, Tryggve Holck Storås

Erschienen in: Magnetic Resonance Materials in Physics, Biology and Medicine | Ausgabe 3/2019

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Abstract

Objective

To investigate the effects of a range of parameter settings on T₁ measurement stability in the portal vein using the T1-mapping sequences Look-Locker (LL) and Modified Look-Locker inversion recovery (MOLLI).

Materials and methods

Ten different versions of LL and MOLLI sequences were tested and compared to a reference sequence provided by the MR manufacturer. Ten healthy volunteers were imaged multiple times on two separate scan days at 3T. The mean T₁ values and coefficient of variation (CoV) were calculated for each of the ten sequences and compared to the reference sequence.

Results

Six of the tested sequences had T₁ values close to the reference sequence; among those, three sequences achieved lower CoV than the reference sequence. Lowest CoV was achieved using a non-triggered LL sequence with 5 beat readout and a 45^o flip angle (mean T₁ 1733 ms ± 89 ms, CoV 1.3% ± 0.58%).

Conclusion

T₁-measurements in the hepatic portal vein can be performed with high precision using either MOLLI or LL sequences provided that LL sampling duration is sufficiently long and flip angle sufficiently high. The advantage of constant timing outweighed the advantage of ECG-triggering.

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Titel: Precision of T1-relaxation time measurements in the hepatic portal vein: influence of measurement technique and sequence parameters
verfasst von: Svein Are Sirirud Vatnehol
Per Kristian Hol
Atle Bjørnerud
Mahmood Amiry-Moghaddam
Camilla Haglerød
Tryggve Holck Storås
Publikationsdatum: 02.01.2019
Verlag: Springer International Publishing
Erschienen in: Magnetic Resonance Materials in Physics, Biology and Medicine / Ausgabe 3/2019
Print ISSN: 0968-5243
Elektronische ISSN: 1352-8661
DOI: https://doi.org/10.1007/s10334-018-00731-1

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Precision of T1-relaxation time measurements in the hepatic portal vein: influence of measurement technique and sequence parameters