Skip to main content
Erschienen in: Intensive Care Medicine 4/2004

01.04.2004 | Original

Prognosis of patients aged 80 years and over admitted in medical intensive care unit

verfasst von: Ariane Boumendil, Eric Maury, Ingrid Reinhard, Laurence Luquel, Georges Offenstadt, Bertrand Guidet

Erschienen in: Intensive Care Medicine | Ausgabe 4/2004

Einloggen, um Zugang zu erhalten

Abstract

Objective

To determine the prognostic indicators of long-term survival after admission to a medical intensive care unit (MICU) for patients aged 80 years and over.

Design

Prospective cohort study.

Setting

A 14-bed MICU in a 970-bed, acute care, tertiary, university hospital in Paris, France.

Patients

A total of 233 patients aged 80 years and over discharged from a MICU during a 2-year period.

Measurements and main results

Severity at admission was estimated using the Simplified Acute Physiology Score. The underlying condition was classified using the MacCabe classification. The functional status was assessed using the Knaus classification. The outcome after MICU discharge was determined after a median 2-year follow-up. The functional outcome was assessed by telephone interviews, employing the Instrumental Activities of Daily Living (IADL). The in-MICU mortality was 19.5% including death occurring during the 2 days following discharge. The long-term survival rates for patients admitted to the MICU were 59% at 2 months, 33% at 2 years, and 29% at 3 years. The multivariate analysis identified two prognostic factors of death after discharge: presence of an underlying fatal disease (HR 1.7; 95% CI 1.1–2.6) and severe functional limitation (HR 1.7; 95% CI 1.2–2.6). The IADL was excellent or good for 56% of the surviving patients.

Conclusion

Long-term survival after MICU is mainly related to the underlying condition, whereas known factors for in-MICU survival do not influence long-term prognosis.
Literatur
1.
Zurück zum Zitat Quang Chi D (1995) La population de la France a l’horizon 2050. INSEE:412 Quang Chi D (1995) La population de la France a l’horizon 2050. INSEE:412
2.
Zurück zum Zitat Fried LP, Kronmal RA, Newman AB, Bild DE, Mittelmark MB, Polak JF, Robbins JA, Gardin JM (1998) Risk factors for 5-years mortality in older adults. The Cardiovascular Health Study. J Am Med Assoc 279:585–592CrossRef Fried LP, Kronmal RA, Newman AB, Bild DE, Mittelmark MB, Polak JF, Robbins JA, Gardin JM (1998) Risk factors for 5-years mortality in older adults. The Cardiovascular Health Study. J Am Med Assoc 279:585–592CrossRef
3.
Zurück zum Zitat Fried LP (2000) Epidemiology of aging. Epidemiol Rev 22:95–106PubMed Fried LP (2000) Epidemiology of aging. Epidemiol Rev 22:95–106PubMed
4.
Zurück zum Zitat Campion EW, Mulley AG, Goldstein RL, Barnett GO, Thibault GE (1981) Medical intensive care for the elderly. A study of current use, costs and outcome. J Am Med Assoc 246:2052–2056CrossRef Campion EW, Mulley AG, Goldstein RL, Barnett GO, Thibault GE (1981) Medical intensive care for the elderly. A study of current use, costs and outcome. J Am Med Assoc 246:2052–2056CrossRef
5.
Zurück zum Zitat Spillman B, Lubitz J (2000) The effect on longevity on spending for acute and longterm care. N Engl J Med 342:1409–1415CrossRefPubMed Spillman B, Lubitz J (2000) The effect on longevity on spending for acute and longterm care. N Engl J Med 342:1409–1415CrossRefPubMed
6.
Zurück zum Zitat Smith S, Stevens V, Edbrooke D, Wilson A, Hibbert C, Kingsley J (1997) The impact of the ageing population on intensive care provision. Nurs Crit Care 2:239–242PubMed Smith S, Stevens V, Edbrooke D, Wilson A, Hibbert C, Kingsley J (1997) The impact of the ageing population on intensive care provision. Nurs Crit Care 2:239–242PubMed
7.
Zurück zum Zitat Jakob SM, Rothen HU (1997) Intensive care 1980–1995: change in patients characteristics, nursing workload and outcome. Intensive Care Med 23:1165–1170PubMed Jakob SM, Rothen HU (1997) Intensive care 1980–1995: change in patients characteristics, nursing workload and outcome. Intensive Care Med 23:1165–1170PubMed
8.
Zurück zum Zitat Groeger JS, Guntupalli KK, Strosberg M, Halpern N, Raphaely RC, Cerra F, Kaye W (1993) Descriptive analysis of critical care units in the united states: patients characteristics and intensive care utilization. Crit Care Med 21:279–291PubMed Groeger JS, Guntupalli KK, Strosberg M, Halpern N, Raphaely RC, Cerra F, Kaye W (1993) Descriptive analysis of critical care units in the united states: patients characteristics and intensive care utilization. Crit Care Med 21:279–291PubMed
9.
Zurück zum Zitat Angus DC, Kelly MA, Schmitz RJ, White A, Popovich J, for the Committee on Manpower for Pulmonary and Critical Care Societies (COMPACCS) (2000) Current and projected workforce requirements for care of the critically ill and patients with pulmonary disease: Can we meet the requirements of an aging population? J Am Med Assoc 284:2762–2770CrossRef Angus DC, Kelly MA, Schmitz RJ, White A, Popovich J, for the Committee on Manpower for Pulmonary and Critical Care Societies (COMPACCS) (2000) Current and projected workforce requirements for care of the critically ill and patients with pulmonary disease: Can we meet the requirements of an aging population? J Am Med Assoc 284:2762–2770CrossRef
10.
Zurück zum Zitat Moreno R, Van Dort A, Rowan K, Apolone G (1997) Highlights of the Euricus-I Data. Organisation and management of intensive care. A prospective study in 12 European countries. Update Intensive Care Emerg Med 29:239–269 Moreno R, Van Dort A, Rowan K, Apolone G (1997) Highlights of the Euricus-I Data. Organisation and management of intensive care. A prospective study in 12 European countries. Update Intensive Care Emerg Med 29:239–269
11.
Zurück zum Zitat Nicolas F, Le Gall JR, Alperovitch A, Loirat P, Villers D (1987) Influence of patients’ age on survival, level of therapy and length of stay in intensive care units. Intensive Care Med 13:9–13PubMed Nicolas F, Le Gall JR, Alperovitch A, Loirat P, Villers D (1987) Influence of patients’ age on survival, level of therapy and length of stay in intensive care units. Intensive Care Med 13:9–13PubMed
12.
Zurück zum Zitat Rockwood K, Noseworthy TW, Gibney RT, Konopad E, Shustack A, Stollery D, Johnston R, Grace M (1993) One-year outcome of elderly and young patients admitted to intensive care units. Crit Care Med 21:687–691PubMed Rockwood K, Noseworthy TW, Gibney RT, Konopad E, Shustack A, Stollery D, Johnston R, Grace M (1993) One-year outcome of elderly and young patients admitted to intensive care units. Crit Care Med 21:687–691PubMed
13.
Zurück zum Zitat Kass JE, Castriotta RJ, Malakoff F (1992) Intensive care unit outcome in the very elderly. Crit Care Med 20:1666–1671PubMed Kass JE, Castriotta RJ, Malakoff F (1992) Intensive care unit outcome in the very elderly. Crit Care Med 20:1666–1671PubMed
14.
Zurück zum Zitat Yu W, Ash A, Levinsky N, Moskowitz M (2000) Intensive care unit use and mortality in the elderly. J Gen Intern Med 15:97–102CrossRefPubMed Yu W, Ash A, Levinsky N, Moskowitz M (2000) Intensive care unit use and mortality in the elderly. J Gen Intern Med 15:97–102CrossRefPubMed
15.
Zurück zum Zitat Chelluri L, Pinsky MR, Donahoe MP, Grenvik A (1993) Long-term outcome of critically ill elderly patients requiring intensive care. J Am Med Assoc 269:3119–3123CrossRef Chelluri L, Pinsky MR, Donahoe MP, Grenvik A (1993) Long-term outcome of critically ill elderly patients requiring intensive care. J Am Med Assoc 269:3119–3123CrossRef
16.
Zurück zum Zitat Mahul P, Perrot D, Tempelhoff G, Gaussorgues P, Jospe R, Ducreux JC, Dumont A, Motin J, Auboyer C, Robert D (1991) Short- and long-term prognosis, functional outcome following ICU for elderly. Intensive Care Med 17:7–10PubMed Mahul P, Perrot D, Tempelhoff G, Gaussorgues P, Jospe R, Ducreux JC, Dumont A, Motin J, Auboyer C, Robert D (1991) Short- and long-term prognosis, functional outcome following ICU for elderly. Intensive Care Med 17:7–10PubMed
17.
Zurück zum Zitat Knaus WA, Harrell FE Jr, Lynn J, Goldman L, Phillips RS, Connors AF Jr, Dawson NV, Fulkerson WJ Jr, Califf RM, Desbiens N (1995) The SUPPORT prognostic model. Objective estimates of survival for seriously ill hospitalized adults. Study to understand prognoses and preferences for outcomes and risks of treatments. Ann Intern Med 122:191–203PubMed Knaus WA, Harrell FE Jr, Lynn J, Goldman L, Phillips RS, Connors AF Jr, Dawson NV, Fulkerson WJ Jr, Califf RM, Desbiens N (1995) The SUPPORT prognostic model. Objective estimates of survival for seriously ill hospitalized adults. Study to understand prognoses and preferences for outcomes and risks of treatments. Ann Intern Med 122:191–203PubMed
18.
Zurück zum Zitat Teno JM, Harrell FE Jr, Knaus W, Phillips RS, Wu AW, Connors A Jr, Wenger NS, Wagner D, Galanos A, Desbiens NA, Lynn J (2000) Prediction of survival for older hospitalized patients: the HELP survival model. Hospitalized Elderly Longitudinal Project. J Am Geriatr Soc 48:S16–S24 Teno JM, Harrell FE Jr, Knaus W, Phillips RS, Wu AW, Connors A Jr, Wenger NS, Wagner D, Galanos A, Desbiens NA, Lynn J (2000) Prediction of survival for older hospitalized patients: the HELP survival model. Hospitalized Elderly Longitudinal Project. J Am Geriatr Soc 48:S16–S24
19.
Zurück zum Zitat Ely EW, Wheeler AP, Thompson BT, Ancukiewicz M, Steinberg KP, Bernard GR (2002) Recovery rate and prognosis in older persons who develop acute lung injury and the acute respiratory distress syndrome. Ann Intern Med 136:25–36PubMed Ely EW, Wheeler AP, Thompson BT, Ancukiewicz M, Steinberg KP, Bernard GR (2002) Recovery rate and prognosis in older persons who develop acute lung injury and the acute respiratory distress syndrome. Ann Intern Med 136:25–36PubMed
20.
Zurück zum Zitat Task Force of the American College of Critical Care Medicine, Society of Critical Care Medicine (1999) Guidelines for intensive care unit admission, discharge and triage. Crit Care Med 27:633–638PubMed Task Force of the American College of Critical Care Medicine, Society of Critical Care Medicine (1999) Guidelines for intensive care unit admission, discharge and triage. Crit Care Med 27:633–638PubMed
21.
Zurück zum Zitat Teasdale G, Jennett B (1974) Assessment of coma and impaired consciousness. A practical scale. Lancet 2:81–84PubMed Teasdale G, Jennett B (1974) Assessment of coma and impaired consciousness. A practical scale. Lancet 2:81–84PubMed
22.
Zurück zum Zitat Le Gall JR, Lemeshow S, Saulnier F (1993) A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. J Am Med Assoc 270:2957–2963CrossRef Le Gall JR, Lemeshow S, Saulnier F (1993) A new simplified acute physiology score (SAPS II) based on a European/North American multicenter study. J Am Med Assoc 270:2957–2963CrossRef
23.
Zurück zum Zitat MacCabe WR, Jackson GG (1962) Gram-negative bacteremia: etiology and ecology. Arch Intern Med 110:847–852 MacCabe WR, Jackson GG (1962) Gram-negative bacteremia: etiology and ecology. Arch Intern Med 110:847–852
24.
Zurück zum Zitat Brun-Buisson C, Doyon F, Carlet J, Dellamonica P, Gouin F, Lepoutre A, Mercier JC, Offenstadt G, Regnier B (1995) Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis. J Am Med Assoc 274:968–974CrossRef Brun-Buisson C, Doyon F, Carlet J, Dellamonica P, Gouin F, Lepoutre A, Mercier JC, Offenstadt G, Regnier B (1995) Incidence, risk factors, and outcome of severe sepsis and septic shock in adults. A multicenter prospective study in intensive care units. French ICU Group for Severe Sepsis. J Am Med Assoc 274:968–974CrossRef
25.
Zurück zum Zitat Knaus WA, Zimmerman JE, Wagner DP, Draper EA, Lawrence DE (1981) APACHE: Acute physiology and chronic health evaluation: a physiologically based classification system. Crit Care Med 9:591–597PubMed Knaus WA, Zimmerman JE, Wagner DP, Draper EA, Lawrence DE (1981) APACHE: Acute physiology and chronic health evaluation: a physiologically based classification system. Crit Care Med 9:591–597PubMed
26.
Zurück zum Zitat Société de réanimation de Langue Française (1986) Utilisation de l’indice de gravité simplifié et du système OMEGA: mise a jour 1986, commission d’évaluation de la Société de Réanimation de Langue Française. Réanimation, Soins Intensifs, Médecine d’Urgence 2:219–221 Société de réanimation de Langue Française (1986) Utilisation de l’indice de gravité simplifié et du système OMEGA: mise a jour 1986, commission d’évaluation de la Société de Réanimation de Langue Française. Réanimation, Soins Intensifs, Médecine d’Urgence 2:219–221
27.
Zurück zum Zitat Montuclard L, Garrouste-Orgeas M, Timsit JF, Misset B, de Jonghe B, Carlet J (2000) Outcome, functional autonomy, and quality of life of elderly patients with a long-term intensive care unit stay. Crit Care Med 28:3389–3395PubMed Montuclard L, Garrouste-Orgeas M, Timsit JF, Misset B, de Jonghe B, Carlet J (2000) Outcome, functional autonomy, and quality of life of elderly patients with a long-term intensive care unit stay. Crit Care Med 28:3389–3395PubMed
28.
Zurück zum Zitat Sznajder M, Leleu G, Buonamico G, Auvert B, Aegerter P, Merliere Y, Dutheil M, Guidet B, Le Gall JR (1998) Estimation of direct cost and resource allocation in intensive care: correlation with the Omega system. Intensive Care Med 24:582–589PubMed Sznajder M, Leleu G, Buonamico G, Auvert B, Aegerter P, Merliere Y, Dutheil M, Guidet B, Le Gall JR (1998) Estimation of direct cost and resource allocation in intensive care: correlation with the Omega system. Intensive Care Med 24:582–589PubMed
29.
Zurück zum Zitat Aegerter P, Auvert B, Buonamico G, Sznajder M, Beauchet B, Guidet B, LeGall JR et CUB-REA (1998) Mise en oeuvre et évaluation d’une base de données commune aux services de réanimation d’Ile-de-France. Rev Epidemiol Sante Publ 46:226–237PubMed Aegerter P, Auvert B, Buonamico G, Sznajder M, Beauchet B, Guidet B, LeGall JR et CUB-REA (1998) Mise en oeuvre et évaluation d’une base de données commune aux services de réanimation d’Ile-de-France. Rev Epidemiol Sante Publ 46:226–237PubMed
30.
Zurück zum Zitat Lawton M, Brody E (1969) Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 9:179–186PubMed Lawton M, Brody E (1969) Assessment of older people: self-maintaining and instrumental activities of daily living. Gerontologist 9:179–186PubMed
31.
Zurück zum Zitat Cox DR, Oakes D (1994) Analysis of survival data. Chapman and Hall, London Cox DR, Oakes D (1994) Analysis of survival data. Chapman and Hall, London
32.
Zurück zum Zitat Altman DG, Andersen PK (1989) Bootstrap investigation of the stability of a Cox regression model. Stat Med 8:771–783PubMed Altman DG, Andersen PK (1989) Bootstrap investigation of the stability of a Cox regression model. Stat Med 8:771–783PubMed
33.
Zurück zum Zitat Courson J, Madinier C (2000) La France continue de vieillir. Le Nord-Pas-de-Calais reste la région la plus jeune. INSEE Première 746 Courson J, Madinier C (2000) La France continue de vieillir. Le Nord-Pas-de-Calais reste la région la plus jeune. INSEE Première 746
34.
Zurück zum Zitat Manton KG, Corder L, Stallard E (1997) Chronic disability trends in elderly United States populations: 1982–1994. Proc Natl Acad Sci USA 94:2593–2598CrossRefPubMed Manton KG, Corder L, Stallard E (1997) Chronic disability trends in elderly United States populations: 1982–1994. Proc Natl Acad Sci USA 94:2593–2598CrossRefPubMed
35.
Zurück zum Zitat Inouye S, Peduzzi P, Robison J, Hughes J, Horwitz R, Concato J (1998) Importance of functional measures in predicting mortality among older hospitalized patients. J Am Med Assoc 279:1187–1193CrossRef Inouye S, Peduzzi P, Robison J, Hughes J, Horwitz R, Concato J (1998) Importance of functional measures in predicting mortality among older hospitalized patients. J Am Med Assoc 279:1187–1193CrossRef
36.
Zurück zum Zitat Chelluri L, Mendelsohn AB, Belle SH, Rotondi AJ, Angus DC, Donahoe MP, Sirio CA, Schulz R, Pinsky MR (2003) Hospital costs in patients receiving prolonged mechanical ventilation: Does age have an impact? Crit Care Med 31:1746–1751CrossRefPubMed Chelluri L, Mendelsohn AB, Belle SH, Rotondi AJ, Angus DC, Donahoe MP, Sirio CA, Schulz R, Pinsky MR (2003) Hospital costs in patients receiving prolonged mechanical ventilation: Does age have an impact? Crit Care Med 31:1746–1751CrossRefPubMed
37.
Zurück zum Zitat Connors AF Jr, Dawson NV, Thomas C, Harrell FE Jr, Desbiens N, Fulkerson WJ, Kussin P, Bellamy P, Goldman L, Knaus WA for the SUPPORT Investigators (1996) Outcomes following acute exacerbation of severe chronic obstructive lung disease Am J Respir Crit Care Med 154:959–967 Connors AF Jr, Dawson NV, Thomas C, Harrell FE Jr, Desbiens N, Fulkerson WJ, Kussin P, Bellamy P, Goldman L, Knaus WA for the SUPPORT Investigators (1996) Outcomes following acute exacerbation of severe chronic obstructive lung disease Am J Respir Crit Care Med 154:959–967
38.
Zurück zum Zitat Hamel MB, Phillips RS, Davis RB, Teno J, Desbiens N, Lynn J, Tsevat J (2001) Are aggressive treatment strategies less cost-effective for older patients? The case of ventilator support and aggressive care for patients with acute respiratory failure. J Am Geriatr Soc 49:382–390CrossRefPubMed Hamel MB, Phillips RS, Davis RB, Teno J, Desbiens N, Lynn J, Tsevat J (2001) Are aggressive treatment strategies less cost-effective for older patients? The case of ventilator support and aggressive care for patients with acute respiratory failure. J Am Geriatr Soc 49:382–390CrossRefPubMed
39.
Zurück zum Zitat Hamel MB, Phillips RS, Teno JM, Lynn J, Galanos AN, Davis RB, Connors AF Jr, Oye RK, Desbiens N, Reding DJ, Goldman L (1996) Seriously ill hospitalized adults: Do we spend less on older patients? Support Investigators. Study to Understand Prognoses and Preference for Outcomes and Risks of Treatments. J Am Geriatr Soc 44:1043–1048PubMed Hamel MB, Phillips RS, Teno JM, Lynn J, Galanos AN, Davis RB, Connors AF Jr, Oye RK, Desbiens N, Reding DJ, Goldman L (1996) Seriously ill hospitalized adults: Do we spend less on older patients? Support Investigators. Study to Understand Prognoses and Preference for Outcomes and Risks of Treatments. J Am Geriatr Soc 44:1043–1048PubMed
40.
Zurück zum Zitat Hamel MB, Lynn J, Teno JM, Covinsky KE, Wu AW, Galanos A, Desbiens NA, Phillips RS (2000) Age-related differences in care preferences, treatment decisions, and clinical outcomes of seriously ill hospitalized adults: lessons from SUPPORT. J Am Geriatr Soc 48:S176–S182 Hamel MB, Lynn J, Teno JM, Covinsky KE, Wu AW, Galanos A, Desbiens NA, Phillips RS (2000) Age-related differences in care preferences, treatment decisions, and clinical outcomes of seriously ill hospitalized adults: lessons from SUPPORT. J Am Geriatr Soc 48:S176–S182
41.
Zurück zum Zitat Kleinpell R, Ferrans C (1998) Factors influencing intensive care unit survival for critically ill elderly patients. Heart Lung 27:337–343PubMed Kleinpell R, Ferrans C (1998) Factors influencing intensive care unit survival for critically ill elderly patients. Heart Lung 27:337–343PubMed
42.
Zurück zum Zitat Ip SP, Leung YF, Ip CY, Mak WP (1999) Outcomes of critically ill elderly patients: Is high-dependency care for geriatric patients worthwhile? Crit Care Med 27:2351–2357PubMed Ip SP, Leung YF, Ip CY, Mak WP (1999) Outcomes of critically ill elderly patients: Is high-dependency care for geriatric patients worthwhile? Crit Care Med 27:2351–2357PubMed
43.
Zurück zum Zitat Ely EW, Evans GW, Haponik EF (1999) Mechanical ventilation in a cohort of elderly patients admitted to an intensive care unit. Ann Intern Med 131:96–104PubMed Ely EW, Evans GW, Haponik EF (1999) Mechanical ventilation in a cohort of elderly patients admitted to an intensive care unit. Ann Intern Med 131:96–104PubMed
44.
Zurück zum Zitat Zilberberg MD, Epstein SK (1998) Acute lung injury in the medical ICU: comorbid conditions, age, etiology, and hospital outcome. Am J Respir Crit Care Med 157:1159–1164PubMed Zilberberg MD, Epstein SK (1998) Acute lung injury in the medical ICU: comorbid conditions, age, etiology, and hospital outcome. Am J Respir Crit Care Med 157:1159–1164PubMed
45.
Zurück zum Zitat Dardaine V, Dequin PF, Ripault H, Constans T, Ginies G (2001) Outcome of older patients requiring ventilatory support in intensive care: impact of nutritional status. J Am Geriatr Soc 49:564–570CrossRefPubMed Dardaine V, Dequin PF, Ripault H, Constans T, Ginies G (2001) Outcome of older patients requiring ventilatory support in intensive care: impact of nutritional status. J Am Geriatr Soc 49:564–570CrossRefPubMed
46.
Zurück zum Zitat Karjosse R (2000) Bilan démographique 1999: hausse de la fécondité et recul de la mortalité. INSEE Première 698 Karjosse R (2000) Bilan démographique 1999: hausse de la fécondité et recul de la mortalité. INSEE Première 698
47.
Zurück zum Zitat Lebeaupin A, Nortier F (1996) Les personnes âgées dépendantes : situation actuelle et perspectives d’avenir. INSEE: Données sociales, La société française, Paris Lebeaupin A, Nortier F (1996) Les personnes âgées dépendantes : situation actuelle et perspectives d’avenir. INSEE: Données sociales, La société française, Paris
48.
Zurück zum Zitat David MG, Starzec C (1996) Aisance à 60 ans, dépendance à 80 ans. INSEE Première 477 David MG, Starzec C (1996) Aisance à 60 ans, dépendance à 80 ans. INSEE Première 477
Metadaten
Titel
Prognosis of patients aged 80 years and over admitted in medical intensive care unit
verfasst von
Ariane Boumendil
Eric Maury
Ingrid Reinhard
Laurence Luquel
Georges Offenstadt
Bertrand Guidet
Publikationsdatum
01.04.2004
Verlag
Springer-Verlag
Erschienen in
Intensive Care Medicine / Ausgabe 4/2004
Print ISSN: 0342-4642
Elektronische ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-003-2150-z

Weitere Artikel der Ausgabe 4/2004

Intensive Care Medicine 4/2004 Zur Ausgabe

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Hinter dieser Appendizitis steckte ein Erreger

23.04.2024 Appendizitis Nachrichten

Schmerzen im Unterbauch, aber sonst nicht viel, was auf eine Appendizitis hindeutete: Ein junger Mann hatte Glück, dass trotzdem eine Laparoskopie mit Appendektomie durchgeführt und der Wurmfortsatz histologisch untersucht wurde.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.