Erschienen in:
13.06.2019 | SPECIAL REVIEW ARTICLE: JSNC RECOMMENDATION
Recommendations for 18F-fluorodeoxyglucose positron emission tomography imaging for diagnosis of cardiac sarcoidosis—2018 update: Japanese Society of Nuclear Cardiology recommendations
verfasst von:
Shinichiro Kumita, MD, PhD, Keiichiro Yoshinaga, MD, PhD, FACC, FASNC, Masao Miyagawa, MD, PhD, Mitsuru Momose, MD, PhD, Keisuke Kiso, MD, PhD, Tokuo Kasai, MD, PhD, Masanao Naya, MD, PhD, Committee for diagnosis of cardiac sarcoidosis using 18F-FDG PET, Japanese Society of Nuclear Cardiology
Erschienen in:
Journal of Nuclear Cardiology
|
Ausgabe 4/2019
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Excerpt
Sarcoidosis is a systemic inflammatory disorder of unknown etiology affecting people of any age.
1,
2 The disease shows heterogeneous distribution of epithelioid granulomatous inflammation without caseous necrosis and unpredictable clinical course.
3 Divergent phenotypes have been identified, and sarcoidosis lesions may involve multiple organs, including the lungs, lymph nodes, eyes, bones, liver, spleen, skin, muscles, nervous system and heart. Although about 20% of patients have chronic progression, in general the inflammation spontaneously resolves, and, therefore, sarcoidosis was previously believed to be a benign disease. However, cardiac involvement is associated with a poor prognosis, accounting for 13% to 25% of deaths from sarcoidosis.
4 The most common causes of death are fatal ventricular arrhythmias and heart failure.
1 Therefore, early detection and treatment are crucial. …
