Skip to main content
Hauptrubriken
CME Facharzt-Training Webinare Zeitschriften Bücher e.Medpedia Podcast
Service
Jobbörse Info & Hilfe
Fachgebiete
Anästhesiologie Allgemeinmedizin Arbeitsmedizin Augenheilkunde Chirurgie Dermatologie Gynäkologie und Geburtshilfe HNO Innere Medizin Kardiologie Neurologie Onkologie und Hämatologie Orthopädie und Unfallchirurgie Pädiatrie Pathologie Psychiatrie Radiologie Rechtsmedizin Urologie Zahnmedizin
Themen
Klimawandel und Gesundheit Neues aus dem Markt COVID-19 Praxis und Beruf Seltene Erkrankungen GOÄ & EBM Panorama
Sammlungen
Kasuistiken Algorithmen & Infografiken Blickdiagnosen Arthropedia FlapFinder (für Dermatochirurgen) Videos Kongressberichterstattung Medizin für Apothekerinnen und Apotheker Für Ärztinnen und Ärzte in Weiterbildung Für Medizinstudierende
Erweiterte Suche
Anmelden
nach oben
Journal of Anesthesia
Erschienen in: Journal of Anesthesia 6/2016

12.09.2016 | Invited Review Article

Remifentanil for labor analgesia: a comprehensive review

verfasst von: Yayoi Ohashi, Leyla Baghirzada, Hiroyuki Sumikura, Mrinalini Balki

Erschienen in: Journal of Anesthesia | Ausgabe 6/2016

Einloggen, um Zugang zu erhalten

Abstract

Japan has seen significant developments in obstetric anesthesia in recent years, including the establishment of the Japanese Society of Obstetric Anesthesia and Perinatology. However, labor pain, which is one of the most important issues in obstetric practice, is still not treated aggressively. The rate of epidural administration for labor analgesia is very low in Japan as compared to other developed countries. Remifentanil has been used for labor analgesia, as part of general anesthesia for cesarean delivery, as well as for various fetal procedures around the world. Intravenous patient-controlled analgesia (IVPCA) with remifentanil is considered to be a reasonable option for labor pain relief. Several studies have demonstrated its efficacy with minimal maternal and neonatal adverse effects. On the other hand, reports of cases of maternal cardiac and respiratory arrest with remifentanil IVPCA within the past couple of years have redirected our attention to its safe use. Remifentanil IVPCA warrants one-to-one nursing monitoring, appropriate education of healthcare providers, continuous maternal oxygen saturation monitoring, end-tidal CO2 monitoring, and availability of both maternal and neonatal resuscitation equipment. This article provides an overview of knowledge and principles of using remifentanil IVPCA for labor analgesia and introduces its potential usage in Japan.
Literatur
1.
Terui K. Comparison of the obstetric anesthesia practice between Japan and USA. Masui. 2009;58(11):1473–5.PubMed
2.
3.
Rooks JP. Labor pain management other than neuraxial: what do we know and where do we go next? Birth. 2012;39(4):318–22.CrossRefPubMed
4.
5.
Pan PH, Eisenach JC. The pain of childbirth and its effects on the mother and the fetus. In: Chestnut DH, Polley L, Tsen LC, Wong CA, editors. Chestnut’s obstetric anesthesia: principles and practice. 4th ed. Philadelphia: Mosby Elsevier; 2009. p. 387–403.CrossRef
6.
7.
Olufolabi AJ, Booth JV, Wakeling HG, Glass PS, Penning DH, Reynolds JD. A preliminary investigation of remifentanil as a labor analgesic. Anesth Analg. 2000;91(3):606–8.CrossRefPubMed
8.
Kapila A, Glass PS, Jacobs JR, Muir KT, Hermann DJ, Shiraishi M, Howell S, Smith RL. Measured context-sensitive half-times of remifentanil and alfentanil. Anesthesiology. 1995;83(5):968–75.CrossRefPubMed
9.
Thompson JP, Rowbotham DJ. Remifentanil—an opioid for the 21st century. Br J Anaesth. 1996;76(3):341–3.CrossRefPubMed
10.
Douma M. Obstetric analgesia: a comparison of patient-controlled meperidine, remifentanil, and fentanyl in labour. Br J Anaesth. 2010;104(2):209–15.CrossRefPubMed
11.
Marwah R, Hassan S, Carvalho JC, Balki M. Remifentanil versus fentanyl for intravenous patient-controlled labour analgesia: an observational study. Can J Anesth. 2012;59(3):246–54.CrossRefPubMed
12.
Volmanen P, Sarvela J, Akural EI, Raudaskoski T, Korttila K, Alahuhta S. Intravenous remifentanil vs. epidural levobupivacaine with fentanyl for pain relief in early labour: a randomised, controlled, double-blinded study. Acta Anaesthesiol Scand. 2008;52:249–55.CrossRefPubMed
13.
Douma MR, Middeldorp JM, Verwey RA, Dahan A, Stienstra R. A randomised comparison of intravenous remifentanil patient-controlled analgesia with epidural ropivacaine/sufentanil during labour. Int J Obstet Anesth. 2011;20(2):118–23.CrossRefPubMed
14.
Tveit TO, Seiler S, Halvorsen A, Rosland JH. Labour analgesia: a randomised, controlled trial comparing intravenous remifentanil and epidural analgesia with ropivacaine and fentanyl. Eur J Anaesth. 2012;29(3):129–36.CrossRef
15.
Stocki D, Matot I, Einav S, Eventov-Friedman S, Ginosar Y, Weiniger CF. A randomized controlled trial of the efficacy and respiratory effects of patient-controlled intravenous remifentanil analgesia and patient-controlled epidural analgesia in laboring women. Anesth Analg. 2014;118(3):589–97.CrossRefPubMed
16.
Leong WL, Sng BL, Sia AT. A comparison between remifentanil and meperidine for labor analgesia: a systematic review. Anesth Analg. 2011;113(4):818–25.CrossRefPubMed
17.
Schnabel A, Hahn N, Broscheit J, Muellenbach RM, Rieger L, Roewer N, Kranke P. Remifentanil for labour analgesia: a meta-analysis of randomised controlled trials. Eur J Anaesthesiol. 2012;29(4):177–85.CrossRefPubMed
18.
Hinova A, Fernando R. Systemic remifentanil for labor analgesia. Anesth Analg. 2009;109(6):1925–9.CrossRefPubMed
19.
Liu ZQ, Chen XB, Li HB, Qiu MT, Duan T. A comparison of remifentanil parturient-controlled intravenous analgesia with epidural analgesia: a meta-analysis of randomized controlled trials. Anesth Analg. 2014;118(3):598–603.CrossRefPubMed
20.
Stourac P, Suchomelova H, Stodulkova M, Huser M, Krikava I, Janku P, Haklova O, Hakl L, Stoudek R, Gal R, Sevcik P. Comparison of parturient-controlled remifentanil with epidural bupivacaine and sufentanil for labour analgesia: randomised controlled trial. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2012;156:227–32.
21.
Ismail MT, Hassanin MZ. Neuraxial analgesia versus intravenous remifentanil for pain relief in early labor in nulliparous women. Arch Gynecol Obstet. 2012;286:1375–81.CrossRefPubMed
22.
Blair JM, Hill DA, Fee JP. Patient-controlled analgesia for labour using remifentanil: a feasibility study. Br J Anaesth. 2001;87(3):415–20.CrossRefPubMed
23.
Volmanen P, Akural EI, Raudaskoski T, Alahuhta S. Remifentanil in obstetric analgesia: a dose-finding study. Anesth Analg. 2002;94(4):913–7.CrossRefPubMed
24.
Tveit TO, Halvorsen A, Seiler S, Rosland JH. Efficacy and side effects of intravenous remifentanil patient-controlled analgesia used in a stepwise approach for labour: an observational study. Int J Obstet Anesth. 2013;22(1):19–25.CrossRefPubMed
25.
Balki M, Kasodekar S, Dhumne S, Bernstein P, Carvalho JC. Remifentanil patient-controlled analgesia for labour: optimizing drug delivery regimens. Can J Anesth. 2007;54(8):626–33.CrossRef
26.
D’Onofrio P, Novelli AM, Mecacci F, Scarselli G. The efficacy and safety of continuous intravenous administration of remifentanil for birth pain relief: an open study of 205 parturients. Anesth Analg. 2009;109(6):1922–4.CrossRefPubMed
27.
Shen MK, Wu ZF, Zhu AB, He LL, Shen XF, Yang JJ, Feng SW. Remifentanil for labour analgesia: a double-blinded, randomised controlled trial of maternal and neonatal effects of patient-controlled analgesia versus continuous infusion. Anaesthesia. 2013;68(3):236–44.CrossRefPubMed
28.
Schwarz GL, Volmanen P, Albrechtsen S, Bjoernestad E. Remifentanil target-controlled infusion during second stage labour in high-risk parturients: a case series. Acta Anaesthesiol Scand. 2013;57(6):802–8.CrossRefPubMed
29.
Sia AT, Sng BL, Leo S. Novel vital signs-controlled, patient-assisted intravenous analgesia using remifentanil for labour and delivery. Int J Obstet Anesth. 2014;23(2):196–8.CrossRefPubMed
30.
Bonner JC, McClymont W. Respiratory arrest in an obstetric patient using remifentanil patient-controlled analgesia. Anaesthesia. 2012;67(5):538–40.CrossRefPubMed
31.
Marr RHJ, Bythell V. Cardiac arrest in an obstetric patient using remifentanil patient-controlled analgesia. Anaesthesia. 2013;68(3):283–7.CrossRefPubMed
32.
Stocki D, Matot I, Einav S, Eventov-Friedman S, Ginosar Y, Weiniger CF. A randomized controlled trial of the efficacy and respiratory effects of patient-controlled intravenous remifentanil analgesia and patient-controlled epidural analgesia in laboring women. Anesth Analg. 2014;118:589–97.CrossRefPubMed
33.
Konefał H, Jaskot B, Czeszyńska MB, Pastuszka J. Remifentanil patient-controlled analgesia for labor–monitoring of newborn heart rate, blood pressure and oxygen saturation during the first 24 hours after delivery. Arch Med Sci. 2013;9(4):697–702.CrossRefPubMed
34.
Hodnett ED. Pain and women’s satisfaction with the experience of childbirth: a systematic review. Am J Obstet Gynecol. 2002;186:S160–72.PubMed
35.
Volmanen PVE, Akural EI, Raudaskoski T, Ranta P, Tekay A, Ohtonen P, Alahuhta S. Timing of intravenous patient-controlled remifentanil bolus during early labour. Acta Anaesthesiol Scand. 2011;55(4):486–94.CrossRefPubMed
36.
Evron S, Glezerman M, Sadan O, Boaz M, Ezri T. Remifentanil: a novel systemic analgesic for labor pain. Anesth Analg. 2005;100:233–8.CrossRefPubMed
37.
Volikas I, Male D. A comparison of pethidine and remifentanil patient-controlled analgesia in labour. Int J Obstet Anesth. 2001;10:86–90.CrossRefPubMed
38.
Thurlow BA, Laxton CH, Dick A, Waterhouse P, Sherman L, Goodman NW. Remifentanil by patient-controlled analgesia compared with intramuscular meperidine for pain relief I labour. Br J Anaesth. 2002;88:374–8.CrossRefPubMed
39.
Volikas I, Butwick A, Wilkinson C, Pleming A, Nicholson G. Maternal and neonatal side-effects of remifentanil patient-controlled analgesia in labour. Br J Anaesth. 2005;95(4):504–9.CrossRefPubMed
40.
Blair JM, Dobson GT, Hill DA, McCracken GR, Fee JPH. Patient controlled analgesia for labour: a comparison of remifentanil with pethidine. Anaesthesia. 2005;60:22–7.CrossRefPubMed
41.
Thurlow JA, Waterhouse P. Patient-controlled analgesia in labour using remifentanil in two parturients with platelet abnormalities. Br J Anaesth. 2000;84(3):411–3.CrossRefPubMed
42.
Jones R, Pregrum A, Stacey GW. Patient-controlled analgesia using remifentanil in the parturient with thrombocytopaenia. Anaesthesia. 1999;54:459–65.CrossRef
43.
Balcioglu O, Akin S, Demir S, Aribogan A. Patient-controlled intravenous analgesia with remifentanil in nulliparous subjects in labor. Expert Opin Pharmacother. 2007;8(18):3089–96.CrossRefPubMed
44.
Roelants F, Franceschi ED, Veyckemans F, Lavand’homme P. Patient-controlled intravenous analgesia using remifentanil in the parturient. Can J Anesth. 2001;48(2):175–8.CrossRefPubMed
45.
Owen MD, Poss MJ, Dean LS, Harper MA. Prolonged intravenous remifentanil infusion for labor analgesia. Anesth Analg. 2002;94(4):918–9.CrossRefPubMed
Metadaten
Titel
Remifentanil for labor analgesia: a comprehensive review
verfasst von
Yayoi Ohashi
Leyla Baghirzada
Hiroyuki Sumikura
Mrinalini Balki
Publikationsdatum
12.09.2016
Verlag
Springer Japan
Erschienen in
Journal of Anesthesia / Ausgabe 6/2016
Print ISSN: 0913-8668
Elektronische ISSN: 1438-8359
DOI
https://doi.org/10.1007/s00540-016-2233-y

Weitere Artikel der Ausgabe 6/2016

Journal of Anesthesia 6/2016 Zur Ausgabe

Clinical Report

Metabolic acidosis with hemodilution due to massive absorption of normal saline as bladder irrigation fluid following holmium laser enucleation of prostate

Retraction Note

Retraction Note to: Assessment of neuromuscular block at the orbicularis oris, corrugator supercilii, and adductor pollicis muscles

Letter to the Editor

Lingual nerve palsy after i-gel® use

Original Article

Prediction of in-hospital mortality and morbidity using high-sensitivity C-reactive protein after burr hole craniostomy

Original Article

The effects of intensive care environment on postoperative nightmare

Original Article

Variations in the distance between the cricoid cartilage and targets of stellate ganglion block in neutral and extended supine positions: an ultrasonographic evaluation

Neu im Fachgebiet AINS

Tipps für den Umgang mit Behandlungsfehlern

01.05.2024 DGIM 2024 Kongressbericht

Es ist nur eine Frage der Zeit, bis es zu einem Zwischenfall kommt und ein Behandlungsfehler passiert. Doch wenn Ärztinnen und Ärzte gut vorbereitet sind, schaffen es alle Beteiligten den Umständen entsprechend gut durch diese Krise. 

Sind Frauen die fähigeren Ärzte?

30.04.2024 Gendermedizin Nachrichten

Patienten, die von Ärztinnen behandelt werden, dürfen offenbar auf bessere Therapieergebnisse hoffen als Patienten von Ärzten. Besonders gilt das offenbar für weibliche Kranke, wie eine Studie zeigt.

Akuter Schwindel: Wann lohnt sich eine MRT?

28.04.2024 Schwindel Nachrichten

Akuter Schwindel stellt oft eine diagnostische Herausforderung dar. Wie nützlich dabei eine MRT ist, hat eine Studie aus Finnland untersucht. Immerhin einer von sechs Patienten wurde mit akutem ischämischem Schlaganfall diagnostiziert.

Bei schweren Reaktionen auf Insektenstiche empfiehlt sich eine spezifische Immuntherapie

25.04.2024 Allergien und Intoleranzreaktionen Nachrichten

Insektenstiche sind bei Erwachsenen die häufigsten Auslöser einer Anaphylaxie. Einen wirksamen Schutz vor schweren anaphylaktischen Reaktionen bietet die allergenspezifische Immuntherapie. Jedoch kommt sie noch viel zu selten zum Einsatz.

Update AINS

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.

hier abonnieren
Bildnachweise