Erschienen in:
13.01.2020 | Letter to the Editor
Response to: Letter to the Editors: Re: Simultaneous PET/MRI in the Evaluation of Breast and Prostate Cancer Using Combined Na[18F]F and [18F]FDG: A Focus on Skeletal Lesions
verfasst von:
Ida Sonni, Ryogo Minamimoto, Lucia Baratto, Andrei Iagaru
Erschienen in:
Molecular Imaging and Biology
|
Ausgabe 2/2020
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Excerpt
High sensitivity is a merit, not a flaw of any of the nuclear medicine studies in our armamentarium. It is upon ourselves to increase specificity through various approaches, not the least being the complementary information from anatomical imaging such as CT or MRI. We are trained to critically interpret each finding in a PET scan and question specificity. The use of hybrid imaging such as MRI in our publication is an important aid to the better characterize PET findings. While the possibility of false positives due to high sensitivity and relative lack of specificity is something we should always keep in mind, we do not think it is of particular relevance here. There are countless reports of non-specific FDG or PSMA uptake, yet we do not stop using them. Moreover, data regarding Na[18F]F uptake in noncancerous lesions are scarce and to our knowledge not studied prospectively. …
