Erschienen in:
01.03.2016 | Scientific Letter
Risk Factors for Steroid Dependency in Children with Idiopathic Nephrotic Syndrome in India
verfasst von:
Lesa Dawman, Amarjeet Mehta, Indar Kumar Sharawat, Rajeev Yadav
Erschienen in:
Indian Journal of Pediatrics
|
Ausgabe 3/2016
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Excerpt
To the Editor: Minimal change nephrotic syndrome (MCNS) is the most common cause of idiopathic nephrotic syndrome (INS) with a 2:1 predilection for boys. INS has a more favourable prognosis and is characterised by steroid responsiveness in approximately 90 % of patients [
1,
2]. The incidence of relapse rate is high and approximately half of them develop steroid dependency. Many predictors of steroid dependency have been proposed
i.e., duration from initial steroid therapy to response, concomitant upper respiratory tract infection during relapse, relapse during the first half year after disease onset, low serum protein level, gender, age at onset, total cholesterol and steroid regimen used. …