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Breast Cancer Research and Treatment

Ausgabe 2/2016

Inhalt (23 Artikel)

Open Access Review

Developmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancer

Maria Cristina Rangel, Daniel Bertolette, Nadia P. Castro, Malgorzata Klauzinska, Frank Cuttitta, David S. Salomon

Preclinical study

Increased CD4 and CD8-positive T cell infiltrate signifies good prognosis in a subset of triple-negative breast cancer

Hirofumi Matsumoto, Aye Aye Thike, Huihua Li, Joe Yeong, Si-lin Koo, Rebecca Alexandra Dent, Puay Hoon Tan, Jabed Iqbal

Open Access Preclinical study

A novel gene expression signature for bone metastasis in breast carcinomas

C. Dilara Savci-Heijink, Hans Halfwerk, Jan Koster, Marc J. van de Vijver

Preclinical study

Effect of ALDH1 on prognosis and chemoresistance by breast cancer subtype

Kumiko Kida, Takashi Ishikawa, Akimitsu Yamada, Kazuhiro Shimada, Kazutaka Narui, Sadatoshi Sugae, Daisuke Shimizu, Mikiko Tanabe, Takeshi Sasaki, Yasushi Ichikawa, Itaru Endo

Preclinical study

Is ultrasound-guided fine-needle aspiration cytology of adequate value in detecting breast cancer patients with three or more positive axillary lymph nodes?

G. M. Kramer, M. W. H. Leenders, L. J. Schijf, H. L. S. Go, T. van der Ploeg, M. P. van den Tol, W. H. Schreurs

Open Access Preclinical study

Equivalence of MammaPrint array types in clinical trials and diagnostics

Inès Beumer, Anke Witteveen, Leonie Delahaye, Diederik Wehkamp, Mireille Snel, Christa Dreezen, John Zheng, Arno Floore, Guido Brink, Bob Chan, Sabine Linn, Rene Bernards, Laura van ’t Veer, Annuska Glas

Clinical Trial

Adherence to the breast cancer surveillance program for women at risk for familial breast and ovarian cancer versus overscreening: a monocenter study in Germany

Lisa Vetter, Monika Keller, Thomas Bruckner, Michael Golatta, Sabine Eismann, Christina Evers, Nicola Dikow, Christof Sohn, Jörg Heil, Sarah Schott

Clinical trial

A phase I/II trial of the safety and clinical activity of a HER2-protein based immunotherapeutic for treating women with HER2-positive metastatic breast cancer

Giuseppe Curigliano, Gilles Romieu, Mario Campone, Thierry Dorval, Lionel Duck, Jean-Luc Canon, Celia Roemer-Becuwe, Mario Roselli, Silvia Neciosup, Wivine Burny, Andrea Callegaro, Pedro Miguel de Sousa Alves, Jamila Louahed, Vincent Brichard, Frédéric F. Lehmann

Clinical trial

Should the hyperechogenic halo around malignant breast lesions be included in the measurement of tumor size?

Judith Joekel, Holm Eggemann, Serban Dan Costa, Atanas Ignatov

Clinical trial

A non-randomized dose-escalation Phase I trial of a protein-based immunotherapeutic for the treatment of breast cancer patients with HER2-overexpressing tumors

Steven A. Limentani, Mario Campone, Thierry Dorval, Giuseppe Curigliano, Richard de Boer, Charles Vogel, Shane White, Thomas Bachelot, Jean-Luc Canon, Mary Disis, Ahmad Awada, Martine Berlière, Frédéric Amant, Ellis Levine, Wivine Burny, Andrea Callegaro, Pedro Miguel de Sousa Alves, Jamila Louahed, Vincent Brichard, Frédéric F. Lehmann

Clinical trial

Revisiting dosing regimen using PK/PD modeling: the MODEL1 phase I/II trial of docetaxel plus epirubicin in metastatic breast cancer patients

Emilie Hénin, Christophe Meille, Dominique Barbolosi, Benoit You, Jérôme Guitton, Athanassios Iliadis, Gilles Freyer

Clinical trial

Competing risks of death in women treated with adjuvant aromatase inhibitors for early breast cancer on NCIC CTG MA.27

Judith-Anne W. Chapman, Lois E. Shepherd, James N. Ingle, Hyman B. Muss, Kathleen I. Pritchard, Karen A. Gelmon, Timothy J. Whelan, Catherine Elliott, Paul E. Goss

Epidemiology

Investigating racial disparities in use of NK1 receptor antagonists to prevent chemotherapy-induced nausea and vomiting among women with breast cancer

Devon K. Check, Katherine E. Reeder-Hayes, Ethan M. Basch, Leah L. Zullig, Morris Weinberger, Stacie B. Dusetzina

Open Access Epidemiology

The clinical value of HER-2 overexpression and PIK3CA mutations in the older breast cancer population: a FOCUS study analysis

Charla C. Engels, Mandy Kiderlen, Esther Bastiaannet, Ronald van Eijk, Antien Mooyaart, Vincent T. H. B. M. Smit, Anton J. M. de Craen, Peter J. K. Kuppen, Judith R. Kroep, Cornelis J. H. van de Velde, Gerrit Jan Liefers

Epidemiology

The impact of oophorectomy on survival after breast cancer in BRCA1-positive breast cancer patients

T. Huzarski, T. Byrski, J. Gronwald, C. Cybulski, O. Oszurek, M. Szwiec, K. Gugała, M. Stawicka, Z. Morawiec, T. Mierzwa, M. Falco, H. Janiszewska, E. Kilar, E. Marczyk, B. Kozak-Klonowska, M. Siołek, D. Surdyka, R. Wiśniowski, M. Posmyk, P. Domagała, P. Sun, J. Lubiński, S. A. Narod

Epidemiology

Effectiveness of bisphosphonate use and risk of contralateral breast cancer and recurrence in women with early-stage breast cancer treated with tamoxifen

Marilyn L. Kwan, Jiaxiao M. Shi, Laurel A. Habel, Jun Song, Joanie W-L Chung, Chantal C. Avila, Joanne E. Schottinger, T. Craig Cheetham, Suzanne W. Fletcher, Reina Haque

Epidemiology

Very low local recurrence rates after breast-conserving therapy: analysis of 8485 patients treated over a 28-year period

S. C. J. Bosma, F. van der Leij, E. van Werkhoven, H. Bartelink, J. Wesseling, S. Linn, E. J. Rutgers, M. J. van de Vijver, P. H. M. Elkhuizen

Erratum

Erratum to: Loss of glucocorticoid receptor activation is a hallmark of BRCA1-mutated breast tissue

Myriam Vilasco, Laudine Communal, Justine Hugon-Rodin, Frédérique Penault-Llorca, Najat Mourra, Zherui Wu, Patricia Forgez, Anne Gompel

Erratum

Erratum to: Low expression of ULK1 is associated with operable breast cancer progression and is an adverse prognostic marker of survival for patients

Jun Tang, Rong Deng, Rong-Zhen Luo, Guo-Ping Shen, Mu-Yan Cai, Zi-Ming Du, Shan Jiang, Ming-Tian Yang, Jian-Hua Fu, Xiao-Feng Zhu

Erratum

Erratum to: PI3K/mTOR inhibition can impair tumor invasion and metastasis in vivo despite a lack of antiproliferative action in vitro: implications for targeted therapy

Seth A. Wander, Dekuang Zhao, Alexandra H. Besser, Feng Hong, Jianqin Wei, Tan A. Ince, Clara Milikowski, Nanette H. Bishopric, Andy J. Minn, Chad J. Creighton, Joyce M. Slingerland

Erratum

Erratum to: RAGE-binding S100A8/A9 promotes the migration and invasion of human breast cancer cells through actin polymerization and epithelial–mesenchymal transition

Chonggao Yin, Hongli Li, Baogang Zhang, Yuqing Liu, Guohua Lu, Shijun Lu, Lei Sun, Yueliang Qi, Xiaolong Li, Weiyi Chen

Erratum

Erratum to: Estrogen receptor beta binds Sp1 and recruits a corepressor complex to the estrogen receptor alpha gene promoter

V. Bartella, P. Rizza, I. Barone, D. Zito, F. Giordano, C. Giordano, S. Catalano, L. Mauro, D. Sisci, M. L. Panno, S. A. W. Fuqua, S. Andò

Umsetzung der POMGAT-Leitlinie läuft

03.05.2024 DCK 2024 Kongressbericht

Seit November 2023 gibt es evidenzbasierte Empfehlungen zum perioperativen Management bei gastrointestinalen Tumoren (POMGAT) auf S3-Niveau. Vieles wird schon entsprechend der Empfehlungen durchgeführt. Wo es im Alltag noch hapert, zeigt eine Umfrage in einem Klinikverbund.

CUP-Syndrom: Künstliche Intelligenz kann Primärtumor finden

30.04.2024 Künstliche Intelligenz Nachrichten

Krebserkrankungen unbekannten Ursprungs (CUP) sind eine diagnostische Herausforderung. KI-Systeme können Pathologen dabei unterstützen, zytologische Bilder zu interpretieren, um den Primärtumor zu lokalisieren.

Sind Frauen die fähigeren Ärzte?

30.04.2024 Gendermedizin Nachrichten

Patienten, die von Ärztinnen behandelt werden, dürfen offenbar auf bessere Therapieergebnisse hoffen als Patienten von Ärzten. Besonders gilt das offenbar für weibliche Kranke, wie eine Studie zeigt.

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

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