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Medical Oncology

Ausgabe 5/2023

Inhalt (30 Artikel)

Original Paper

Gold cluster encapsulated liposomes: theranostic agent with stimulus triggered release capability

Seyed Mohammad Amini, Seyed Mahdi Rezayat, Rassoul Dinarvand, Sharmin Kharrazi, Mahmoud Reza Jaafari

Original Paper

Anticancer activity of lycopene in HT-29 colon cancer cell line

Dilara Ataseven, Ayşegül Öztürk, Mustafa Özkaraca, Ziad Joha

Original Paper

Demethylase FTO enhances the PI3K/Akt signaling to promote gastric cancer malignancy

Yuxuan Zhu, Jing Yang, Yongxiang Li, Jiegou Xu, Zheng Fang

Original Paper

Determination of Rutin's antitumoral effect on EAC solid tumor by AgNOR count and PI3K/AKT/mTOR signaling pathway

Seher Yılmaz, Züleyha Doğanyiğit, Aslı Okan Oflamaz, Şükrü Ateş, Evrim Suna Arıkan Söylemez, Mehtap Nisari, Ammad Ahmad Farooqı

Original Paper

Steroidal saponin SSPH I induces ferroptosis in HepG2 cells via regulating iron metabolism

Dan Huang, Xin Dong, Jianzhe Li, Yudan Chen, Ying Zhou, Qingjie Chen, Yuewen Sun

Original Paper

Network pharmacology-based anti-pancreatic cancer potential of kaempferol and catechin of Trema orientalis L. through computational approach

Shreni Agrawal, Richa Das, Amit Kumar Singh, Pradeep Kumar, Praveen Kumar Shukla, Indrani Bhattacharya, Amit Kumar Tripathi, Sunil Kumar Mishra, Kavindra Nath Tiwari

Open Access Original Paper

Toxoplasma gondii-derived antigen modifies tumor microenvironment of Ehrlich solid carcinoma murine model and enhances immunotherapeutic activity of cyclophosphamide

Cherine A. Ismail, Maha M. Eissa, Maha R. Gaafar, Layla K. Younis, Nahla El Skhawy

Original Paper

YAP transduction drives triple-negative breast cancer aggressiveness through modulating the EGFR‒AKT axis in patient-derived xenograft cells

Sulfath Thottungal Parambil, Santhosh Kumar R. Thankayyan, Gisha Rose Antony, Ajeesh Babu Littleflower, Paul Augustine, Thara Somanathan, Lakshmi Subhadradevi

Open Access Original Paper

Investigation of oncolytic effect of recombinant Newcastle disease virus in primary and metastatic oral melanoma

Supaporn Numpadit, Chiaki Ito, Takaaki Nakaya, Katsuro Hagiwara

Original Paper

The effects of KIR2DL4 stimulated NK-92 cells on the apoptotic pathways of HER2 + /HER-breast cancer cells

Nil Kilic, Mohammadreza Dastouri, Irfan Kandemir, Erkan Yilmaz

Original Paper

Extracellular vesicles, hyperadhesive von willebrand factor, and outcomes of gastric cancer: a clinical observational study

Wei Cai, Min Wang, Chen-yu Wang, Chan-yuan Zhao, Xiao-yu Zhang, Quan Zhou, Wen-jie Zhao, Feng Yang, Chen-li Zhang, Ai-jun Yang, Jing-fei Dong, Min Li

Original Paper

Zoledronic acid induces ferroptosis by upregulating POR in osteosarcoma

Hong Jiacong, Yang Qirui, Li Haonan, Song Yichang, Chen Yan, Chen Keng

Original Paper

Association between homologous recombination gene variants and efficacy of oxaliplatin-based chemotherapy in advanced pancreatic cancer: prospective multicenter observational study

Tomohiro Kondo, Masashi Kanai, Junichi Matsubara, Daisuke Yamaguchi, Takashi Ura, Tadayuki Kou, Toshinao Itani, Motoo Nomura, Taro Funakoshi, Akira Yokoyama, Keitaro Doi, Masashi Tamaoki, Michio Yoshimura, Norimitsu Uza, Takahiro Yamada, Toshihiko Masui, Sachiko Minamiguchi, Shigemi Matsumoto, Hideki Ishikawa, Manabu Muto

Original Paper

Efficacy and safety of HAIC alone vs. HAIC combined with lenvatinib for treatment of advanced hepatocellular carcinoma

Fang Long, Shali Chen, Ruidong Li, Yinsheng Lin, Jian Han, Jiandong Guo, Yongxin Chen, Chengzhi Li, Peng Song

Open Access Original Paper

Cryopreventive temperatures prior to chemotherapy

A. Ibrahim, E. Camci, L. Khairallah, M. Jontell, J. Walladbegi

Open Access Original Paper

HIF1α-dependent and independent pathways regulate the expression of PD-L1 in prostate cancer

Erasmia T. Xanthopoulou, Christos Kakouratos, Christos Nanos, Anastasia G. Gkegka, Christos Kalaitzis, Alexandra Giatromanolaki, Michael I. Koukourakis

Original Paper

ErbB2-upregulated HK1 and HK2 promote breast cancer cell proliferation, migration and invasion

Xuejiao Ma, Jingruo Chen, Bohan Huang, Shiqi Fu, Shuai Qu, Rong Yu, Yuhua Zhao

Review Article

The impact of hypoxia on extracellular vesicle secretome profile of cancer

Keywan Mortezaee, Jamal Majidpoor

Review Article

Understanding the functional relevance of oral neutrophils, phenotype and properties in OSCC

Sudhansubala Lenka, Rajesh Kumar Bhola, Pavankumar R. Varanasi, Sanat Kumar Bhuyan, Ruchi Bhuyan

Review Article

Establishing the applicability of cancer vaccines in combination with chemotherapeutic entities: current aspect and achievable prospects

Nirjari Kothari, Humzah Postwala, Aanshi Pandya, Aayushi Shah, Yesha Shah, Mehul R. Chorawala

Open Access Review Article

Revisiting macrophages in ovarian cancer microenvironment: development, function and interaction

Amr Ahmed El-Arabey, Samia S. Alkhalil, Samia T. Al-Shouli, Maaweya E. Awadalla, Heba W. Alhamdi, Taghreed N. Almanaa, Samah Saif Eldin M. Mohamed, Mohnad Abdalla

Review Article

Molecular mechanisms augmenting resistance to current therapies in clinics among cervical cancer patients

Soumik Das, Achsha Babu, Tamma Medha, Gnanasambandan Ramanathan, Anirban Goutam Mukherjee, Uddesh Ramesh Wanjari, Reshma Murali, Sandra Kannampuzha, Abilash Valsala Gopalakrishnan, Kaviyarasi Renu, Debottam Sinha, C. George Priya Doss

Review Article

l-Asparaginase as the gold standard in the treatment of acute lymphoblastic leukemia: a comprehensive review

María Tosta Pérez, Lisandra Herrera Belén, Pablo Letelier, Yolanda Calle, Adalberto Pessoa, Jorge G. Farías

Review Article

A review of recent advances in the novel therapeutic targets and immunotherapy for lung cancer

Avinash Khadela, Humzah Postwala, Deval Rana, Hetvi Dave, Ketan Ranch, Sai H. S. Boddu

Review Article

CAR-modified immune cells as a rapidly evolving approach in the context of cancer immunotherapies

Mohammed Hikmat Faeq, Maysoon Al-Haideri, Talar Ahmad Merza Mohammad, Farshad gharebakhshi, Faroogh Marofi, Safa Tahmasebi, Shadan Modaresahmadi

Short Communication

Myofascial pain syndrome in the oncologic patient: general considerations

Leonado Arce Gálvez, Claudia Liliana Buitrago Martín, Christian Vladimir Guauque Marcelo, Rafael Enrico Valencia Gómez

Erhebliches Risiko für Kehlkopfkrebs bei mäßiger Dysplasie

29.05.2024 Larynxkarzinom Nachrichten

Fast ein Viertel der Personen mit mäßig dysplastischen Stimmlippenläsionen entwickelt einen Kehlkopftumor. Solche Personen benötigen daher eine besonders enge ärztliche Überwachung.

15% bedauern gewählte Blasenkrebs-Therapie

29.05.2024 Urothelkarzinom Nachrichten

Ob Patienten und Patientinnen mit neu diagnostiziertem Blasenkrebs ein Jahr später Bedauern über die Therapieentscheidung empfinden, wird einer Studie aus England zufolge von der Radikalität und dem Erfolg des Eingriffs beeinflusst.

Erhöhtes Risiko fürs Herz unter Checkpointhemmer-Therapie

28.05.2024 Nebenwirkungen der Krebstherapie Nachrichten

Kardiotoxische Nebenwirkungen einer Therapie mit Immuncheckpointhemmern mögen selten sein – wenn sie aber auftreten, wird es für Patienten oft lebensgefährlich. Voruntersuchung und Monitoring sind daher obligat.

Costims – das nächste heiße Ding in der Krebstherapie?

28.05.2024 Onkologische Immuntherapie Nachrichten

„Kalte“ Tumoren werden heiß – CD28-kostimulatorische Antikörper sollen dies ermöglichen. Am besten könnten diese in Kombination mit BiTEs und Checkpointhemmern wirken. Erste klinische Studien laufen bereits.

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