Erschienen in:
01.01.2011 | Editorial
Swept under the carpet? The role of mucociliary clearance in ventilator-induced lung injury
verfasst von:
Cory M. Yamashita, Ruud A. W. Veldhuizen
Erschienen in:
Intensive Care Medicine
|
Ausgabe 1/2011
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Excerpt
Mechanical ventilation (MV) remains one of the major areas of intensive research in critical care and respiratory medicine [
1]. This intervention acts as a life-saving tool in a diverse range of clinical scenarios, but is associated with a host of potentially deleterious side-effects. Its widespread use in the intensive care setting underscores the importance of investigating both causes and mechanisms by which this supportive treatment may be harmful. Experimental and clinical studies have focussed on the effects of mechanical ventilation on either causing direct lung injury, propagating existing lung injury or predisposing the lung to subsequent complications. …