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Journal of Assisted Reproduction and Genetics

Erschienen in:

01.11.2012 | Assisted Reproduction Technologies

The predictive value of high-magnification sperm morphology examination on ICSI outcomes in the presence of oocyte dysmorphisms

verfasst von: Amanda Souza Setti, Daniela Paes Almeida Ferreira Braga, Rita Cassia Savio Figueira, Assumpto Iaconelli Jr., Edson Borges Jr.

Erschienen in: Journal of Assisted Reproduction and Genetics | Ausgabe 11/2012

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Abstract

Purpose

To evaluate the relationship between oocyte dysmorphisms and IMSI outcomes

Methods

Data of IMSI cycles performed in 332 patients were included in this study. Patients were included only if presented more than four and less than 30 oocytes upon oocyte retrieval. Patients who underwent IMSI were matched, concerning female age and sperm parameters, with patients who underwent ICSI in the same period (n = 332). The two groups (ICSI and IMSI) were compared with regard to treatment outcomes. The influence of IMSI on fertilization and embryo quality on D3 and D5, when oocyte dysmorphisms were present was analyzed.

Results

A total of 6444 oocytes were morphologically evaluated and injected. Regardless of the oocyte quality, IMSI performance was a determinant of the increased odds of development to high quality embryo on D3 (OR: 1.98; CI: 1.54–2.56) and D5 (OR: 3.27; CI: 1.61–6.66).

Conclusions

The selection of a morphologically normal spermatozoon under high-magnification is associated with increased embryo quality, regardless of the oocyte morphology. The injection of a spermatozoon, selected under high-magnification, into a morphologically normal oocyte leads to the highest probability of developing high quality embryos.

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Titel: The predictive value of high-magnification sperm morphology examination on ICSI outcomes in the presence of oocyte dysmorphisms
verfasst von: Amanda Souza Setti
Daniela Paes Almeida Ferreira Braga
Rita Cassia Savio Figueira
Assumpto Iaconelli Jr.
Edson Borges Jr.
Publikationsdatum: 01.11.2012
Verlag: Springer US
Erschienen in: Journal of Assisted Reproduction and Genetics / Ausgabe 11/2012
Print ISSN: 1058-0468
Elektronische ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-012-9868-x

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The predictive value of high-magnification sperm morphology examination on ICSI outcomes in the presence of oocyte dysmorphisms