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Experimental Brain Research

Erschienen in:

01.07.2019 | Research Article

Transcranial alternating current stimulation over the prefrontal cortex enhances episodic memory recognition

verfasst von: Tomonori Nomura, Akihiko Asao, Ayumi Kumasaka

Erschienen in: Experimental Brain Research | Ausgabe 7/2019

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Abstract

It remains unknown whether transcranial alternating current stimulation (tACS) affects episodic memory and the effect of gamma oscillations delivered to the left prefrontal cortex (PFC) on long-term memory retention has not been fully investigated. We examined whether tACS over the left PFC enhances recognition of episodic memory. The study enrolled 36 healthy young adult volunteers. The participants were randomly assigned to either a tACS group [n = 18; 14 females; mean age ± standard deviation (SD): 21.2 ± 0.4 years] or a sham-control group [n = 18; 14 females; mean age ± SD: 21.2 ± 0.4 years]. Participants received either tACS or sham stimulation both during the learning task that was conducted on day 1 and during a recognition task on day 2. The recognition task was also conducted on days 1 and 7, and response accuracy was measured at all three time points (days 1, 2, and 7). Patients in the tACS group were better able to retain long-term memory than those in the sham-control group. These findings suggest that tACS over the left PFC enhances recognition of episodic memory in healthy young adults.

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Titel: Transcranial alternating current stimulation over the prefrontal cortex enhances episodic memory recognition
verfasst von: Tomonori Nomura
Akihiko Asao
Ayumi Kumasaka
Publikationsdatum: 01.07.2019
Verlag: Springer Berlin Heidelberg
Erschienen in: Experimental Brain Research / Ausgabe 7/2019
Print ISSN: 0014-4819
Elektronische ISSN: 1432-1106
DOI: https://doi.org/10.1007/s00221-019-05543-w

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